HK1154589A1 - 螺酮縮醇衍生物的結晶及其製備方法 - Google Patents
螺酮縮醇衍生物的結晶及其製備方法Info
- Publication number
- HK1154589A1 HK1154589A1 HK11108698.5A HK11108698A HK1154589A1 HK 1154589 A1 HK1154589 A1 HK 1154589A1 HK 11108698 A HK11108698 A HK 11108698A HK 1154589 A1 HK1154589 A1 HK 1154589A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- crystal
- production
- spiroketal derivative
- spiroketal
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/04—Carbocyclic radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008162073 | 2008-06-20 | ||
| PCT/JP2009/061226 WO2009154276A1 (ja) | 2008-06-20 | 2009-06-19 | スピロケタール誘導体の結晶およびその製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1154589A1 true HK1154589A1 (zh) | 2012-04-27 |
Family
ID=41434188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK11108698.5A HK1154589A1 (zh) | 2008-06-20 | 2011-08-17 | 螺酮縮醇衍生物的結晶及其製備方法 |
Country Status (25)
| Country | Link |
|---|---|
| US (2) | US8569520B2 (zh) |
| EP (3) | EP3170834B8 (zh) |
| JP (2) | JP4823385B2 (zh) |
| KR (1) | KR101856784B1 (zh) |
| CN (1) | CN102046645B (zh) |
| AR (1) | AR072211A1 (zh) |
| AU (1) | AU2009261129A1 (zh) |
| CA (1) | CA2727923A1 (zh) |
| CL (1) | CL2010001485A1 (zh) |
| CO (1) | CO6351798A2 (zh) |
| CR (1) | CR20110033A (zh) |
| EC (1) | ECSP11010773A (zh) |
| ES (1) | ES2907611T3 (zh) |
| HK (1) | HK1154589A1 (zh) |
| IL (1) | IL210098A0 (zh) |
| MA (1) | MA32530B1 (zh) |
| MX (1) | MX2010014023A (zh) |
| NZ (1) | NZ589961A (zh) |
| PE (1) | PE20110115A1 (zh) |
| PL (1) | PL3170834T3 (zh) |
| RU (1) | RU2011101972A (zh) |
| SG (1) | SG193795A1 (zh) |
| TW (1) | TW201011043A (zh) |
| WO (1) | WO2009154276A1 (zh) |
| ZA (1) | ZA201100016B (zh) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011074675A1 (ja) * | 2009-12-18 | 2011-06-23 | 中外製薬株式会社 | スピロケタール誘導体の製造方法 |
| WO2012115249A1 (ja) * | 2011-02-25 | 2012-08-30 | 中外製薬株式会社 | スピロケタール誘導体の結晶 |
| MX355016B (es) * | 2011-10-06 | 2018-04-02 | Bayer Ip Gmbh | Heterociclilpiri(mi)dinilpirazoles como fungicidas. |
| RU2700164C2 (ru) * | 2013-12-27 | 2019-09-13 | Чугаи Сейяку Кабусики Кайся | Твердые препараты, содержащие тофоглифлозин, и способ их получения |
| CN106188190B (zh) * | 2016-07-28 | 2020-08-25 | 迪嘉药业集团有限公司 | 一种托格列净一水合物的制备方法 |
| CN109843279A (zh) | 2016-10-19 | 2019-06-04 | 勃林格殷格翰国际有限公司 | 包含ssao/vap-1抑制剂和sglt2抑制剂的药物组合、其用途 |
| CN108640958B (zh) * | 2017-05-05 | 2021-03-30 | 镇江圣安医药有限公司 | 异苯并呋喃衍生物、其药物组合物和制剂以及用途 |
| EP3781166A1 (en) | 2018-04-17 | 2021-02-24 | Boehringer Ingelheim International GmbH | Pharmaceutical composition, methods for treating and uses thereof |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL63968A (en) * | 1980-10-01 | 1985-10-31 | Glaxo Group Ltd | Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it |
| HU196775B (en) | 1986-08-05 | 1989-01-30 | Richter Gedeon Vegyeszet | Process for production of morfologically unique new modifications of famotidin and medical compositions containing such substances |
| PT98344B (pt) | 1991-07-17 | 1999-04-30 | Lneti Lab Nac De Eng Tec Ind D | Processo para a obtencao de espirocetais labdanicos do tipo ambar cinzento |
| GB9426103D0 (en) | 1994-12-23 | 1995-02-22 | Merck Sharp & Dohme | Therapeutic agents |
| JP2000044534A (ja) * | 1998-07-28 | 2000-02-15 | Mitsui Chemicals Inc | Ｎ保護基アミノ酸の製造法 |
| US6946559B2 (en) | 2000-02-02 | 2005-09-20 | Banyu Pharmaceutical Co., Ltd. | Method of converting functional group through halogen-metal exchange reaction |
| JP3849024B2 (ja) | 2003-03-26 | 2006-11-22 | 国立大学法人 東京大学 | 有機亜鉛錯体およびその製造方法 |
| TW200637869A (en) * | 2005-01-28 | 2006-11-01 | Chugai Pharmaceutical Co Ltd | The spiroketal derivatives and the use as therapeutical agent for diabetes of the same |
| ATE549341T1 (de) | 2005-12-23 | 2012-03-15 | Ecobiotics Ltd | Spiroketale |
| WO2007140191A2 (en) | 2006-05-23 | 2007-12-06 | Theracos, Inc. | Glucose transport inhibitors and methods of use |
| TWI403516B (zh) | 2006-07-27 | 2013-08-01 | Chugai Pharmaceutical Co Ltd | To replace spirocyclic alcohol derivatives, and its use as a therapeutic agent for diabetes |
| JP5791983B2 (ja) | 2011-07-07 | 2015-10-07 | 三井化学株式会社 | 樹脂組成物、これを用いたポリイミド金属積層体、及び電子回路用基板 |
-
2009
- 2009-06-18 TW TW098120460A patent/TW201011043A/zh unknown
- 2009-06-19 US US13/000,208 patent/US8569520B2/en active Active
- 2009-06-19 PL PL16202285T patent/PL3170834T3/pl unknown
- 2009-06-19 AR ARP090102252A patent/AR072211A1/es not_active Application Discontinuation
- 2009-06-19 RU RU2011101972/04A patent/RU2011101972A/ru not_active Application Discontinuation
- 2009-06-19 EP EP16202285.9A patent/EP3170834B8/en active Active
- 2009-06-19 CA CA2727923A patent/CA2727923A1/en not_active Abandoned
- 2009-06-19 PE PE2010001159A patent/PE20110115A1/es not_active Application Discontinuation
- 2009-06-19 ES ES16202285T patent/ES2907611T3/es active Active
- 2009-06-19 KR KR1020117000778A patent/KR101856784B1/ko active IP Right Grant
- 2009-06-19 EP EP22155547.7A patent/EP4036100A1/en not_active Withdrawn
- 2009-06-19 JP JP2010517979A patent/JP4823385B2/ja active Active
- 2009-06-19 SG SG2013061510A patent/SG193795A1/en unknown
- 2009-06-19 EP EP09766724.0A patent/EP2308886B1/en active Active
- 2009-06-19 MX MX2010014023A patent/MX2010014023A/es not_active Application Discontinuation
- 2009-06-19 NZ NZ589961A patent/NZ589961A/xx not_active IP Right Cessation
- 2009-06-19 CN CN200980119081.4A patent/CN102046645B/zh active Active
- 2009-06-19 AU AU2009261129A patent/AU2009261129A1/en not_active Abandoned
- 2009-06-19 WO PCT/JP2009/061226 patent/WO2009154276A1/ja active Application Filing
-
2010
- 2010-12-19 IL IL210098A patent/IL210098A0/en unknown
- 2010-12-20 MA MA33442A patent/MA32530B1/fr unknown
- 2010-12-20 CL CL2010001485A patent/CL2010001485A1/es unknown
-
2011
- 2011-01-03 ZA ZA2011/00016A patent/ZA201100016B/en unknown
- 2011-01-19 CR CR20110033A patent/CR20110033A/es not_active Application Discontinuation
- 2011-01-20 EC EC2011010773A patent/ECSP11010773A/es unknown
- 2011-01-20 CO CO11005627A patent/CO6351798A2/es not_active Application Discontinuation
- 2011-08-17 HK HK11108698.5A patent/HK1154589A1/zh unknown
- 2011-09-05 JP JP2011193271A patent/JP5485237B2/ja active Active
-
2013
- 2013-09-24 US US14/034,880 patent/US9163051B2/en active Active
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