HK1152898A1 - Beta turn peptidomimetic cyclic compounds for treating dry eye - Google Patents

Beta turn peptidomimetic cyclic compounds for treating dry eye

Info

Publication number
HK1152898A1
HK1152898A1 HK11107167.9A HK11107167A HK1152898A1 HK 1152898 A1 HK1152898 A1 HK 1152898A1 HK 11107167 A HK11107167 A HK 11107167A HK 1152898 A1 HK1152898 A1 HK 1152898A1
Authority
HK
Hong Kong
Prior art keywords
dry eye
cyclic compounds
treating dry
beta turn
peptidomimetic cyclic
Prior art date
Application number
HK11107167.9A
Other languages
English (en)
Chinese (zh)
Inventor
Garth Cumberlidge
Karen Meerovitch
Teresa Lama
Uri H Saragovi
Original Assignee
Mimetogen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mimetogen Pharmaceuticals Inc filed Critical Mimetogen Pharmaceuticals Inc
Publication of HK1152898A1 publication Critical patent/HK1152898A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/12—Cyclic peptides with only normal peptide bonds in the ring
    • C07K5/123—Tripeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
HK11107167.9A 2008-04-04 2011-07-11 Beta turn peptidomimetic cyclic compounds for treating dry eye HK1152898A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12303608P 2008-04-04 2008-04-04
US20887309P 2009-02-27 2009-02-27
PCT/US2009/002121 WO2009123761A1 (en) 2008-04-04 2009-04-03 Beta-turn peptidomimetic cyclic compounds for treating dry eye

Publications (1)

Publication Number Publication Date
HK1152898A1 true HK1152898A1 (en) 2012-03-16

Family

ID=40897413

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11107167.9A HK1152898A1 (en) 2008-04-04 2011-07-11 Beta turn peptidomimetic cyclic compounds for treating dry eye

Country Status (10)

Country Link
US (4) US8293713B2 (de)
EP (1) EP2271337B1 (de)
JP (2) JP5480242B2 (de)
KR (1) KR101565185B1 (de)
CN (1) CN102046166B (de)
AU (1) AU2009232352B2 (de)
CA (1) CA2720141C (de)
ES (1) ES2521515T3 (de)
HK (1) HK1152898A1 (de)
WO (1) WO2009123761A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2720141C (en) 2008-04-04 2014-01-28 Mimetogen Pharmaceuticals Inc. Beta-turn peptidomimetic cyclic compounds for treating dry eye
AU2013277637C1 (en) * 2012-06-22 2019-10-24 Mimetogen Pharmaceuticals Inc. Synthesis of beta-turn peptidomimetic cyclic compounds
KR20150004652A (ko) 2013-07-03 2015-01-13 삼성디스플레이 주식회사 표시 패널, 이를 포함하는 표시 장치 및 이를 이용하는 영상 표시 방법
JP6267003B2 (ja) * 2014-02-27 2018-01-24 参天製薬株式会社 ジクアホソルまたはその塩およびレバミピドまたはその塩を組み合わせたことを特徴とする涙液分泌促進剤
US10624781B2 (en) 2015-01-12 2020-04-21 Kedalion Therapeutics, Inc. Micro-droplet delivery device and methods
JP2018515153A (ja) 2015-04-10 2018-06-14 ケダリオン セラピューティックス，インコーポレイテッド 交換式アンプルを備えた圧電式ディスペンサ
KR102056257B1 (ko) 2015-07-09 2019-12-16 미메토젠 파르마슈티칼스 인크. 베타-턴 펩티도미메틱 사이클릭 염의 용액상 합성 및 결정화
KR101718733B1 (ko) 2015-08-21 2017-03-22 국제약품 주식회사 레바미피드의 가용화 방법 및 이에 의해 제조된 안구건조증 치료용 액제
CA3016546A1 (en) 2016-03-04 2017-09-08 James M. Rynerson Method of treating an eye disorder by inhibiting or disrupting bacterial biofilm formation
KR20230107693A (ko) 2017-01-20 2023-07-17 노파르티스 아게 압전 유체 분배기
CN111712219A (zh) 2017-12-08 2020-09-25 科达莱昂治疗公司 流体递送对准系统
CN110092799B (zh) * 2018-01-29 2021-11-12 广州丹康医药生物有限公司 一种环状化合物、其制备方法和应用
US11679028B2 (en) 2019-03-06 2023-06-20 Novartis Ag Multi-dose ocular fluid delivery system
BR112022020948A2 (pt) 2020-04-17 2023-04-11 Kedallion Therapeutics Inc Sistema de distribuição livre de conservantes hidrodinamicamente atuado
US11938057B2 (en) 2020-04-17 2024-03-26 Bausch + Lomb Ireland Limited Hydrodynamically actuated preservative free dispensing system
JP2024520670A (ja) * 2021-06-02 2024-05-24 ザ テキサス エーアンドエム ユニヴァーシティ システム Ｔｒｋ受容体の選択的小分子アゴニスト及び部分アゴニスト
WO2023069255A1 (en) * 2021-10-20 2023-04-27 Stealth Biotherapeutics Inc. Methods and compositions comprising peptidomimitics for treating, preventing, inhibiting, ameliorating or delaying the onset of ophthalmic conditions
CA3234071A1 (en) * 2021-10-20 2023-04-27 Stealth Biotherapeutics Inc. Methods and compositions comprising peptidomimitics for treating, preventing, inhibiting, ameliorating or delaying the onset of ophthalmic conditions

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8917217D0 (en) * 1989-07-27 1989-09-13 Smith & Nephew Ophthalmic compositions
US5545617A (en) * 1993-11-12 1996-08-13 The Schepens Eye Research Institute, Inc. Therapeutic regulation of abnormal conjunctival goblet cell mucous secretion
EP1041996A4 (de) * 1997-12-22 2003-05-14 Human Genome Sciences Inc Keratinozyten wachstumsfaktor-2 formulierungen
JP2001064198A (ja) * 1999-08-24 2001-03-13 Teika Seiyaku Kk 角膜疾患治療剤
WO2001052843A1 (en) * 2000-01-18 2001-07-26 Mcgill University β-TURN PEPTIDOMIMETIC CYCLIC COMPOUNDS
DE602005012812D1 (de) 2005-06-13 2009-04-02 Primm Srl Heterodimere Peptide mit NGF Aktivität und deren Verwendung zur Behandlung von neurodegenerativen Krankheiten
EP1921087A1 (de) 2006-11-10 2008-05-14 Primm S.R.L. Verfahren zur Herstellung von cyclischen Peptiden
JP5576659B2 (ja) * 2006-12-05 2014-08-20 ザ ロイヤル インスティテューション フォー ジ アドバンスメント オブ ラーニング／ マギル ユニバーシティ Ｔｒｋレセプター調節因子の使用方法
CA2720141C (en) * 2008-04-04 2014-01-28 Mimetogen Pharmaceuticals Inc. Beta-turn peptidomimetic cyclic compounds for treating dry eye
ES2512717T3 (es) * 2009-02-27 2014-10-24 Mimetogen Pharmaceuticals Inc. Compuestos cíclicos peptidomiméticos para el tratamiento de la retinitis pigmentosa
AU2013277637C1 (en) * 2012-06-22 2019-10-24 Mimetogen Pharmaceuticals Inc. Synthesis of beta-turn peptidomimetic cyclic compounds

Also Published As

Publication number Publication date
US20140274910A1 (en) 2014-09-18
KR101565185B1 (ko) 2015-11-02
JP5870348B2 (ja) 2016-02-24
CA2720141C (en) 2014-01-28
JP2014080447A (ja) 2014-05-08
CN102046166A (zh) 2011-05-04
JP2011516477A (ja) 2011-05-26
US20160082072A1 (en) 2016-03-24
CN102046166B (zh) 2012-10-17
AU2009232352A1 (en) 2009-10-08
US20120322747A1 (en) 2012-12-20
CA2720141A1 (en) 2009-10-08
JP5480242B2 (ja) 2014-04-23
EP2271337A1 (de) 2011-01-12
AU2009232352B2 (en) 2013-09-05
US8293713B2 (en) 2012-10-23
US8748391B2 (en) 2014-06-10
KR20110010712A (ko) 2011-02-07
ES2521515T3 (es) 2014-11-12
US9156882B2 (en) 2015-10-13
EP2271337B1 (de) 2014-09-03
WO2009123761A1 (en) 2009-10-08
US20110105410A1 (en) 2011-05-05
US9707267B2 (en) 2017-07-18

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