HK1152041A1 - Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene a4 hydrolase - Google Patents

Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene a4 hydrolase

Info

Publication number
HK1152041A1
HK1152041A1 HK11106213.5A HK11106213A HK1152041A1 HK 1152041 A1 HK1152041 A1 HK 1152041A1 HK 11106213 A HK11106213 A HK 11106213A HK 1152041 A1 HK1152041 A1 HK 1152041A1
Authority
HK
Hong Kong
Prior art keywords
yloxy
phenyl
thiazolopyrazin
thiazolopyridin
leukotriene
Prior art date
Application number
HK11106213.5A
Other languages
English (en)
Inventor
Genesis M Bacani
Diego Broggini
Eugene Y Cheung
Christa C Chrovian
Xiaohu Deng
Anne M Fourine
Laurent Gomez
Cheryl A Grice
Aaron M Kearney
Adrienne M Landry-Bayle
Alice Lee-Dutra
Jimmy T Liang
Susanne Lochner
Neelakandha S Mani
Alejandro Santillan
Kathleen C Sappey
Kia Sepassi
Virginia M Tanis
Alvah T Wickboldt
John J M Wiener
Hartmut Zinser
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1152041A1 publication Critical patent/HK1152041A1/xx

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
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    • A61P11/06—Antiasthmatics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
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  • Immunology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HK11106213.5A 2008-04-11 2011-06-16 Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene a4 hydrolase HK1152041A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4434908P 2008-04-11 2008-04-11
US14912909P 2009-02-02 2009-02-02
PCT/US2009/040070 WO2009126806A2 (en) 2008-04-11 2009-04-09 Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene a4 hydrolase

Publications (1)

Publication Number Publication Date
HK1152041A1 true HK1152041A1 (en) 2012-02-17

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HK11106213.5A HK1152041A1 (en) 2008-04-11 2011-06-16 Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene a4 hydrolase
HK11112776.2A HK1158208A1 (en) 2008-04-11 2011-11-24 Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene a4 hydrolase

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US (3) US7939527B2 (ja)
EP (2) EP2336125B1 (ja)
JP (2) JP5530423B2 (ja)
KR (1) KR101228378B1 (ja)
CN (1) CN102056933B (ja)
AR (1) AR072353A1 (ja)
AU (1) AU2009234140B2 (ja)
BR (1) BRPI0911336A2 (ja)
CA (1) CA2721099C (ja)
CL (1) CL2009000877A1 (ja)
CO (1) CO6260069A2 (ja)
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DK (2) DK2336125T3 (ja)
EA (1) EA018802B1 (ja)
EC (1) ECSP10010558A (ja)
ES (2) ES2400875T3 (ja)
HK (2) HK1152041A1 (ja)
HN (1) HN2010002074A (ja)
HR (2) HRP20130278T1 (ja)
IL (2) IL208480A (ja)
JO (1) JO2911B1 (ja)
MX (1) MX2010011154A (ja)
MY (1) MY157597A (ja)
NI (1) NI201000168A (ja)
NZ (2) NZ599853A (ja)
PE (1) PE20091779A1 (ja)
PH (1) PH12013500094A1 (ja)
PL (2) PL2336125T3 (ja)
PT (2) PT2268646E (ja)
RS (2) RS53081B (ja)
SI (2) SI2336125T1 (ja)
SV (1) SV2010003694A (ja)
TW (2) TW201420100A (ja)
UY (1) UY31760A (ja)
WO (1) WO2009126806A2 (ja)
ZA (1) ZA201008054B (ja)

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