HK1144956A1 - Sdf-1 binding nucleic acids and the use thereof sdf-1 - Google Patents
Sdf-1 binding nucleic acids and the use thereof sdf-1Info
- Publication number
- HK1144956A1 HK1144956A1 HK10111312.6A HK10111312A HK1144956A1 HK 1144956 A1 HK1144956 A1 HK 1144956A1 HK 10111312 A HK10111312 A HK 10111312A HK 1144956 A1 HK1144956 A1 HK 1144956A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- sdf
- nucleic acids
- binding nucleic
- binding
- acids
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- C12N2310/00—Structure or type of the nucleic acid
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/351—Conjugate
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- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Rheumatology (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07015379 | 2007-08-06 | ||
EP08008312 | 2008-04-30 | ||
EP08011024 | 2008-06-18 | ||
PCT/EP2008/006473 WO2009019007A2 (en) | 2007-08-06 | 2008-08-06 | Sdf-1 binding nucleic acids and the use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1144956A1 true HK1144956A1 (en) | 2011-03-18 |
Family
ID=39867983
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK10111312.6A HK1144956A1 (en) | 2007-08-06 | 2010-12-06 | Sdf-1 binding nucleic acids and the use thereof sdf-1 |
Country Status (21)
Country | Link |
---|---|
US (3) | US8772257B2 (ja) |
EP (1) | EP2190991B1 (ja) |
JP (1) | JP5815945B2 (ja) |
KR (1) | KR101589442B1 (ja) |
CN (1) | CN101796188B (ja) |
AU (1) | AU2008285939B2 (ja) |
BR (1) | BRPI0815094B8 (ja) |
CA (1) | CA2695061C (ja) |
DK (1) | DK2190991T3 (ja) |
ES (1) | ES2768051T3 (ja) |
HK (1) | HK1144956A1 (ja) |
HR (1) | HRP20200117T1 (ja) |
HU (1) | HUE047459T2 (ja) |
LT (1) | LT2190991T (ja) |
MX (1) | MX2010001490A (ja) |
PL (1) | PL2190991T3 (ja) |
PT (1) | PT2190991T (ja) |
RU (1) | RU2612388C2 (ja) |
SG (2) | SG10201600632QA (ja) |
SI (1) | SI2190991T1 (ja) |
WO (1) | WO2009019007A2 (ja) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2135949E (pt) * | 2006-02-14 | 2013-01-07 | Noxxon Pharma Ag | Ácidos nucleicos que se ligam à mcp-1 |
JP5380287B2 (ja) | 2006-07-18 | 2014-01-08 | ノクソン・ファルマ・アクチエンゲゼルシャフト | Sdf−1結合核酸 |
PT2190991T (pt) * | 2007-08-06 | 2019-12-16 | Noxxon Pharma Ag | Ácidos nucleicos que se ligam a sdf 1 e a sua utilização |
WO2012025251A1 (en) | 2010-08-27 | 2012-03-01 | Noxxon Pharma Ag | Nucleic acids for treatment of chronic complications of diabetes |
DK2613789T3 (en) | 2010-09-09 | 2018-07-23 | Noxxon Pharma Ag | SDF-1-binding nucleic acids and their use in cancer treatment |
JP5843189B2 (ja) * | 2011-03-15 | 2016-01-13 | 国立大学法人名古屋大学 | Sdf−1阻害剤を含有した軟骨組織再生用組成物 |
WO2013155347A1 (en) * | 2012-04-11 | 2013-10-17 | Izumi Raquel | Bruton's tyrosine kinase inhibitors for hematopoietic mobilization |
EP3733868A3 (en) | 2013-10-28 | 2021-01-13 | DOTS Technology Corp. | Allergen detection |
JP6532141B2 (ja) * | 2014-09-26 | 2019-06-19 | ヘリックスミス カンパニー リミテッド | 肝細胞増殖因子及びストローマ細胞由来因子1αを用いた末梢動脈疾患の予防または治療用組成物 |
WO2016197491A1 (en) * | 2015-06-12 | 2016-12-15 | Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences | A three-dimensional tissue scaffold with stem cell attracting element and use thereof |
GB201522223D0 (en) * | 2015-12-16 | 2016-01-27 | Ucl Business Plc | Therapeutic T cells |
US11371045B2 (en) * | 2016-04-15 | 2022-06-28 | Noxxon Pharma Ag | Method of modulating the number and the distribution of tumor-infiltrating leukocytes in tumors |
CA3050691A1 (en) | 2017-01-17 | 2018-07-26 | Dana-Farber Cancer Institute, Inc. | Compositions and methods for treating lysosomal storage diseases and disorders |
US20230301950A1 (en) | 2020-06-26 | 2023-09-28 | Raqualia Pharma Inc. | Method for selecting cancer patients for whom combination therapy with retinoid and cancer therapeutic agent is effective, and combination medicament with retinoid and cancer therapeutic agent |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6011020A (en) * | 1990-06-11 | 2000-01-04 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligand complexes |
US5567588A (en) * | 1990-06-11 | 1996-10-22 | University Research Corporation | Systematic evolution of ligands by exponential enrichment: Solution SELEX |
US5840867A (en) | 1991-02-21 | 1998-11-24 | Gilead Sciences, Inc. | Aptamer analogs specific for biomolecules |
US5582981A (en) | 1991-08-14 | 1996-12-10 | Gilead Sciences, Inc. | Method for identifying an oligonucleotide aptamer specific for a target |
WO1999048528A1 (fr) * | 1998-03-24 | 1999-09-30 | Chugai Seiyaku Kabushiki Kaisha | Inhibiteurs de vascularisation |
NZ514091A (en) * | 1999-03-11 | 2004-01-30 | Rmf Dictagene S | Vascular adhesion molecules and modulation of their function |
JP2003502282A (ja) * | 1999-04-08 | 2003-01-21 | ザ ゼネラル ホスピタル コーポレーション | ヒト転移性細胞の作用因子源から離れた意図された移動 |
US6949243B1 (en) * | 1999-11-24 | 2005-09-27 | Schering Corporation | Methods of inhibiting metastasis |
EP1133988A1 (en) | 2000-03-11 | 2001-09-19 | Biognostik Gesellschaft für biomolekulare Diagnostik mbH | Mixture comprising an inhibitor or suppressor of a gene and a molecule binding to an expression product of that gene |
WO2001094420A1 (en) * | 2000-06-05 | 2001-12-13 | The Trustees Of Columbia University In The City Of New York | Identification and use of human bone marrow-derived endothelial progenitor cells to improve myocardial function after ischemic injury |
JP4233092B2 (ja) | 2001-06-07 | 2009-03-04 | ケモセントリックス, インコーポレイテッド | 細胞移動アッセイ |
US7468253B2 (en) | 2001-06-07 | 2008-12-23 | Chemocentryx, Inc. | Method for multiple chemokine receptor screening for antagonists using RAM assay |
GB0225833D0 (en) * | 2002-11-06 | 2002-12-11 | Univ Leeds | Nucleic acid ligands and uses therefor |
CA2989941A1 (en) | 2004-09-23 | 2006-03-30 | Arc Pharmaceuticals, Inc. | Pharmaceutical compostions and methods relating to inhibiting fibrous adhesions or inflammatory disease using low sulphate fucans |
EP1817414B1 (de) * | 2004-11-29 | 2010-07-14 | Noxxon Pharma AG | Vasopressin bindende l-nukleinsäure |
JP2009531283A (ja) * | 2006-02-02 | 2009-09-03 | アラーガン、インコーポレイテッド | 眼系疾患の処置のための組成物および方法 |
JP5380287B2 (ja) * | 2006-07-18 | 2014-01-08 | ノクソン・ファルマ・アクチエンゲゼルシャフト | Sdf−1結合核酸 |
MX2009003306A (es) * | 2006-10-02 | 2009-04-23 | Medarex Inc | Anticuerpos humanos que se unen a cxcr4 y sus usos. |
EP2407558A1 (en) * | 2006-10-31 | 2012-01-18 | Noxxon Pharma AG | Methods for the detection of a single- or double-stranded nucleic acid molecule |
US8114608B2 (en) * | 2006-11-30 | 2012-02-14 | University Of Virginia Patent Foundation | Methods for treating and diagnosing fibrotic and fibroproliferative diseases |
PT2190991T (pt) * | 2007-08-06 | 2019-12-16 | Noxxon Pharma Ag | Ácidos nucleicos que se ligam a sdf 1 e a sua utilização |
US20090274687A1 (en) * | 2008-05-02 | 2009-11-05 | University Of Miami | Attenuation of hypoxia induced cardiovascular disorders |
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