DK2190991T3 - SDF-1-Bindende nucleinsyrer og anvendelsen deraf - Google Patents
SDF-1-Bindende nucleinsyrer og anvendelsen deraf Download PDFInfo
- Publication number
- DK2190991T3 DK2190991T3 DK08801526.8T DK08801526T DK2190991T3 DK 2190991 T3 DK2190991 T3 DK 2190991T3 DK 08801526 T DK08801526 T DK 08801526T DK 2190991 T3 DK2190991 T3 DK 2190991T3
- Authority
- DK
- Denmark
- Prior art keywords
- sdf
- nucleic acids
- binding nucleic
- binding
- acids
- Prior art date
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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- C12N2310/00—Structure or type of the nucleic acid
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- C12N2310/16—Aptamers
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Physics & Mathematics (AREA)
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Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07015379 | 2007-08-06 | ||
EP08008312 | 2008-04-30 | ||
EP08011024 | 2008-06-18 | ||
PCT/EP2008/006473 WO2009019007A2 (en) | 2007-08-06 | 2008-08-06 | Sdf-1 binding nucleic acids and the use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2190991T3 true DK2190991T3 (da) | 2020-02-10 |
Family
ID=39867983
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08801526.8T DK2190991T3 (da) | 2007-08-06 | 2008-08-06 | SDF-1-Bindende nucleinsyrer og anvendelsen deraf |
Country Status (21)
Country | Link |
---|---|
US (3) | US8772257B2 (da) |
EP (1) | EP2190991B1 (da) |
JP (1) | JP5815945B2 (da) |
KR (1) | KR101589442B1 (da) |
CN (1) | CN101796188B (da) |
AU (1) | AU2008285939B2 (da) |
BR (1) | BRPI0815094B8 (da) |
CA (1) | CA2695061C (da) |
DK (1) | DK2190991T3 (da) |
ES (1) | ES2768051T3 (da) |
HK (1) | HK1144956A1 (da) |
HR (1) | HRP20200117T1 (da) |
HU (1) | HUE047459T2 (da) |
LT (1) | LT2190991T (da) |
MX (1) | MX2010001490A (da) |
PL (1) | PL2190991T3 (da) |
PT (1) | PT2190991T (da) |
RU (1) | RU2612388C2 (da) |
SG (2) | SG10201600632QA (da) |
SI (1) | SI2190991T1 (da) |
WO (1) | WO2009019007A2 (da) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE510014T1 (de) * | 2006-02-14 | 2011-06-15 | Noxxon Pharma Ag | Mcp-i-bindende nukleinsäuren |
ES2663404T3 (es) | 2006-07-18 | 2018-04-12 | Noxxon Pharma Ag | Ácidos nucleicos de unión a SDF-1 |
JP5815945B2 (ja) | 2007-08-06 | 2015-11-17 | ノクソン・ファルマ・アクチエンゲゼルシャフト | Sdf−1結合核酸およびその使用 |
WO2012025251A1 (en) | 2010-08-27 | 2012-03-01 | Noxxon Pharma Ag | Nucleic acids for treatment of chronic complications of diabetes |
MX357770B (es) * | 2010-09-09 | 2018-07-24 | Noxxon Pharma Ag Star | Ácidos nucleicos de enlace sdf-1 y el uso de los mismos en el tratamiento de cáncer. |
JP5843189B2 (ja) * | 2011-03-15 | 2016-01-13 | 国立大学法人名古屋大学 | Sdf−1阻害剤を含有した軟骨組織再生用組成物 |
WO2013155347A1 (en) * | 2012-04-11 | 2013-10-17 | Izumi Raquel | Bruton's tyrosine kinase inhibitors for hematopoietic mobilization |
CN105849323A (zh) | 2013-10-28 | 2016-08-10 | 多茨设备公司 | 过敏原检测 |
CN107073078B (zh) * | 2014-09-26 | 2021-07-06 | 赫利世弥斯株式会社 | 利用肝细胞生长因子和基质细胞衍生因子1α的用于预防或治疗外周动脉疾病的组合物 |
US11213613B2 (en) * | 2015-06-12 | 2022-01-04 | Institute Of Genetics And Developmental Biology, Chinese Academy Of Sciences | Three-dimensional tissue scaffold with stem cell attracting element and use thereof |
GB201522223D0 (en) * | 2015-12-16 | 2016-01-27 | Ucl Business Plc | Therapeutic T cells |
EP3443095A1 (en) * | 2016-04-15 | 2019-02-20 | Noxxon Pharma AG | Method of modulating the number and the distribution of tumor-infiltrating leukocytes in tumors |
AU2018210853B2 (en) | 2017-01-17 | 2023-09-28 | Children's Medical Center Corporation | Compositions and methods for treating lysosomal storage diseases and disorders |
WO2018136434A1 (en) | 2017-01-17 | 2018-07-26 | Children's Medical Center Corporation | Compositions and methods for diagnosing and treating peroxisomal diseases |
CN115997122A (zh) | 2020-06-26 | 2023-04-21 | 拉夸里亚创药株式会社 | 类维生素a与癌治疗剂的组合疗法有效的癌患者的选择方法、及类维生素a与癌治疗剂的组合药物 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6011020A (en) * | 1990-06-11 | 2000-01-04 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligand complexes |
US5567588A (en) * | 1990-06-11 | 1996-10-22 | University Research Corporation | Systematic evolution of ligands by exponential enrichment: Solution SELEX |
US5840867A (en) * | 1991-02-21 | 1998-11-24 | Gilead Sciences, Inc. | Aptamer analogs specific for biomolecules |
US5582981A (en) * | 1991-08-14 | 1996-12-10 | Gilead Sciences, Inc. | Method for identifying an oligonucleotide aptamer specific for a target |
EP1072273B1 (en) * | 1998-03-24 | 2006-07-26 | Chugai Seiyaku Kabushiki Kaisha | Vascularization inhibitors |
DE60045681D1 (de) * | 1999-03-11 | 2011-04-14 | Merck Serono Sa | Vaskuläre adhesionsmoleküle und modulierung ihrer funktion |
EP1169348B1 (en) * | 1999-04-08 | 2016-02-24 | The General Hospital Corporation | Purposeful movement of human migratory cells away from an agent source |
US6949243B1 (en) * | 1999-11-24 | 2005-09-27 | Schering Corporation | Methods of inhibiting metastasis |
EP1133988A1 (en) * | 2000-03-11 | 2001-09-19 | Biognostik Gesellschaft für biomolekulare Diagnostik mbH | Mixture comprising an inhibitor or suppressor of a gene and a molecule binding to an expression product of that gene |
JP5414958B2 (ja) * | 2000-06-05 | 2014-02-12 | ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク | ヒト骨髄由来内皮前駆細胞の同定、及び虚血性傷害後の心筋細胞の機能を改善するためのヒト骨髄由来内皮前駆細胞の使用 |
WO2002101350A2 (en) * | 2001-06-07 | 2002-12-19 | Chemocentryx | Cell migration assay |
US7468253B2 (en) * | 2001-06-07 | 2008-12-23 | Chemocentryx, Inc. | Method for multiple chemokine receptor screening for antagonists using RAM assay |
GB0225833D0 (en) * | 2002-11-06 | 2002-12-11 | Univ Leeds | Nucleic acid ligands and uses therefor |
EP1809303B1 (en) * | 2004-09-23 | 2019-03-06 | ARC Medical Devices, Inc. | Pharmaceutical compositions and methods relating to inhibiting fibrous adhesions or inflammatory disease using low sulphate fucans |
CN101111598B (zh) * | 2004-11-29 | 2013-03-27 | 诺松制药股份公司 | 结合加压素的l-核酸 |
EP1993584B1 (en) * | 2006-02-02 | 2012-05-30 | Allergan, Inc. | Inhibitors of CXCR4 activity for use in the treatment of ocular disorders |
ES2663404T3 (es) * | 2006-07-18 | 2018-04-12 | Noxxon Pharma Ag | Ácidos nucleicos de unión a SDF-1 |
CA2665239A1 (en) * | 2006-10-02 | 2008-05-22 | Medarex, Inc. | Human antibodies that bind cxcr4 and uses thereof |
EP2407558A1 (en) * | 2006-10-31 | 2012-01-18 | Noxxon Pharma AG | Methods for the detection of a single- or double-stranded nucleic acid molecule |
EP2100140B1 (en) * | 2006-11-30 | 2015-05-06 | University Of Virginia Patent Foundation | Methods for diagnosing fibrotic lung diseases |
JP5815945B2 (ja) * | 2007-08-06 | 2015-11-17 | ノクソン・ファルマ・アクチエンゲゼルシャフト | Sdf−1結合核酸およびその使用 |
US20090274687A1 (en) * | 2008-05-02 | 2009-11-05 | University Of Miami | Attenuation of hypoxia induced cardiovascular disorders |
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