HK1136846A1 - Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy - Google Patents

Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy

Info

Publication number
HK1136846A1
HK1136846A1 HK10103472.9A HK10103472A HK1136846A1 HK 1136846 A1 HK1136846 A1 HK 1136846A1 HK 10103472 A HK10103472 A HK 10103472A HK 1136846 A1 HK1136846 A1 HK 1136846A1
Authority
HK
Hong Kong
Prior art keywords
therapy
cells
methods
conditioned media
cell expansion
Prior art date
Application number
HK10103472.9A
Other languages
English (en)
Chinese (zh)
Inventor
Meretzki Shai
Aberman Zami
Burger Ora
Original Assignee
Pluristem Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38522837&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1136846(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pluristem Ltd filed Critical Pluristem Ltd
Publication of HK1136846A1 publication Critical patent/HK1136846A1/xx

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0668—Mesenchymal stem cells from other natural sources
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
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    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • A61P7/06—Antianaemics
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653—Adipocytes; Adipose tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0669—Bone marrow stromal cells; Whole bone marrow
    • A—HUMAN NECESSITIES
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • C12N2513/00—3D culture
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    • C12N2531/00—Microcarriers
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers

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  • Health & Medical Sciences (AREA)
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  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Developmental Biology & Embryology (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
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  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Neurosurgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
HK10103472.9A 2006-03-23 2010-04-08 Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy HK1136846A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78476906P 2006-03-23 2006-03-23
US84708806P 2006-09-26 2006-09-26
PCT/IL2007/000380 WO2007108003A2 (en) 2006-03-23 2007-03-22 Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy

Publications (1)

Publication Number Publication Date
HK1136846A1 true HK1136846A1 (en) 2010-07-09

Family

ID=38522837

Family Applications (5)

Application Number Title Priority Date Filing Date
HK10103472.9A HK1136846A1 (en) 2006-03-23 2010-04-08 Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
HK13104666.0A HK1177759A1 (zh) 2006-03-23 2012-01-17 用於細胞展開的方法以及由其生產的細胞和條件培養基用於治療的用途
HK14100827.3A HK1187950A1 (en) 2006-03-23 2012-01-17 Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
HK12100543.8A HK1160174A1 (en) 2006-03-23 2012-01-17 Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
HK16105449.8A HK1217513A1 (zh) 2006-03-23 2016-05-12 細胞擴增方法和藉此產生的細胞和條件培養基用於治療的用途

Family Applications After (4)

Application Number Title Priority Date Filing Date
HK13104666.0A HK1177759A1 (zh) 2006-03-23 2012-01-17 用於細胞展開的方法以及由其生產的細胞和條件培養基用於治療的用途
HK14100827.3A HK1187950A1 (en) 2006-03-23 2012-01-17 Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
HK12100543.8A HK1160174A1 (en) 2006-03-23 2012-01-17 Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
HK16105449.8A HK1217513A1 (zh) 2006-03-23 2016-05-12 細胞擴增方法和藉此產生的細胞和條件培養基用於治療的用途

Country Status (21)

Country Link
US (2) US20110129447A1 (pl)
EP (5) EP2548951B1 (pl)
JP (3) JP5733894B2 (pl)
KR (2) KR101490449B1 (pl)
CN (1) CN105296415A (pl)
AU (1) AU2007228341B2 (pl)
BR (1) BRPI0709349A2 (pl)
CA (1) CA2646384C (pl)
DK (2) DK2626417T3 (pl)
ES (3) ES2549528T3 (pl)
HK (5) HK1136846A1 (pl)
HR (1) HRP20160538T1 (pl)
HU (1) HUE028796T2 (pl)
IL (1) IL236213A (pl)
MX (1) MX2008012085A (pl)
PL (2) PL2366775T3 (pl)
PT (3) PT2626417E (pl)
RU (1) RU2433177C2 (pl)
SG (1) SG170761A1 (pl)
SI (1) SI2548951T1 (pl)
WO (1) WO2007108003A2 (pl)

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US8790637B2 (en) 2003-06-27 2014-07-29 DePuy Synthes Products, LLC Repair and regeneration of ocular tissue using postpartum-derived cells
US9592258B2 (en) 2003-06-27 2017-03-14 DePuy Synthes Products, Inc. Treatment of neurological injury by administration of human umbilical cord tissue-derived cells
US9572840B2 (en) 2003-06-27 2017-02-21 DePuy Synthes Products, Inc. Regeneration and repair of neural tissue using postpartum-derived cells
EP2336298B1 (en) 2003-06-27 2016-02-17 DePuy Synthes Products, Inc. Postpartum cells derived from placental tissue and methods of making and using the same
WO2007070870A1 (en) 2005-12-16 2007-06-21 Ethicon, Inc. Compositions and methods for inhibiting adverse immune response in histocompatibility-mismatched transplantation
US9125906B2 (en) 2005-12-28 2015-09-08 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using umbilical cord tissue-derived cells
CA2646384C (en) * 2006-03-23 2020-03-24 Pluristem Ltd. Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
US9102915B2 (en) 2006-11-13 2015-08-11 DePuy Synthes Products, Inc. In vitro expansion of postpartum-derived cells using microcarriers
KR20150039214A (ko) * 2007-02-12 2015-04-09 안트로제네시스 코포레이션 태반 줄기세포를 이용한 염증 질환의 치료
JP5162784B2 (ja) * 2007-07-11 2013-03-13 日東電工株式会社 細胞培養基材及びその製造方法並びに細胞培養方法
AU2013267050B2 (en) * 2007-09-19 2016-01-07 Pluristem Ltd. Adherent cells from adipose or placenta tissues and use thereof in therapy
PT2200622E (pt) * 2007-09-19 2012-11-06 Pluristem Ltd Células aderentes provenientes de tecido adiposo ou placentário e respetiva utilização terapêutica
EP2641606A1 (en) 2008-05-27 2013-09-25 Pluristem Ltd. Methods of treating inflammatory colon diseases
RU2563518C2 (ru) 2008-08-20 2015-09-20 Антродженезис Корпорейшн Улучшенная клеточная композиция и способы ее получения
US8524496B2 (en) * 2008-09-02 2013-09-03 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
EP2334310B1 (en) * 2008-09-02 2016-06-29 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
EP2331957B1 (en) * 2008-09-02 2016-11-02 Pluristem Ltd. Methods of selection of cells for transplantation
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