HK1128242A1 - Indication of dosage of progesterone in the treatment of a traumatic brain injury - Google Patents
Indication of dosage of progesterone in the treatment of a traumatic brain injuryInfo
- Publication number
- HK1128242A1 HK1128242A1 HK09107489.4A HK09107489A HK1128242A1 HK 1128242 A1 HK1128242 A1 HK 1128242A1 HK 09107489 A HK09107489 A HK 09107489A HK 1128242 A1 HK1128242 A1 HK 1128242A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- progesterone
- dosage
- indication
- treatment
- brain injury
- Prior art date
Links
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 title abstract 5
- 229960003387 progesterone Drugs 0.000 title abstract 2
- 239000000186 progesterone Substances 0.000 title abstract 2
- 208000030886 Traumatic Brain injury Diseases 0.000 title 1
- 230000009529 traumatic brain injury Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 4
- 208000001738 Nervous System Trauma Diseases 0.000 abstract 3
- 210000003169 central nervous system Anatomy 0.000 abstract 3
- 208000028412 nervous system injury Diseases 0.000 abstract 3
- 206010030113 Oedema Diseases 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 230000016273 neuron death Effects 0.000 abstract 1
- 239000000583 progesterone congener Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66472805P | 2005-03-24 | 2005-03-24 | |
US72966305P | 2005-10-24 | 2005-10-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1128242A1 true HK1128242A1 (en) | 2009-10-23 |
Family
ID=36987966
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK08107067.5A HK1112579A1 (en) | 2005-03-24 | 2008-06-25 | Dosage regimen for the treatment of a traumatic brain injury with progesterone |
HK08107230.7A HK1112581A1 (en) | 2005-03-24 | 2008-06-30 | Methods for the treatment of central nervous system injury via a tapered administration of progesterone |
HK09107489.4A HK1128242A1 (en) | 2005-03-24 | 2009-08-14 | Indication of dosage of progesterone in the treatment of a traumatic brain injury |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK08107067.5A HK1112579A1 (en) | 2005-03-24 | 2008-06-25 | Dosage regimen for the treatment of a traumatic brain injury with progesterone |
HK08107230.7A HK1112581A1 (en) | 2005-03-24 | 2008-06-30 | Methods for the treatment of central nervous system injury via a tapered administration of progesterone |
Country Status (16)
Country | Link |
---|---|
US (4) | US20090221544A1 (xx) |
EP (5) | EP1871382B1 (xx) |
JP (5) | JP5295755B2 (xx) |
AT (2) | ATE520404T1 (xx) |
AU (2) | AU2006226811B2 (xx) |
CA (2) | CA2601715C (xx) |
CY (2) | CY1111478T1 (xx) |
DE (1) | DE602006020353D1 (xx) |
DK (2) | DK1868614T3 (xx) |
ES (2) | ES2428313T3 (xx) |
HK (3) | HK1112579A1 (xx) |
HR (2) | HRP20110198T1 (xx) |
PL (2) | PL1868614T3 (xx) |
PT (2) | PT2030622E (xx) |
RS (1) | RS52471B (xx) |
WO (2) | WO2006102596A2 (xx) |
Families Citing this family (40)
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US7473687B2 (en) | 2005-03-24 | 2009-01-06 | Emory University | Methods for the treatment of a traumatic central nervous system injury |
ES2428313T3 (es) | 2005-03-24 | 2013-11-07 | Emory University | Métodos para el tratamiento de lesiones del sistema nervioso central mediante un protocolo de administración decreciente |
EP2052724A1 (en) * | 2007-10-26 | 2009-04-29 | sanofi-aventis | Use of norgestimate as a selective inhibitor of TRPC3, TRPC6 and TRPC6 and TRPC7 ion channel |
EP2260052A4 (en) | 2008-02-26 | 2013-01-16 | Univ Emory | STEROIDANALOGA FOR NEUROPROTEKTION |
MX2011003015A (es) | 2008-09-18 | 2011-11-18 | Univ Northwestern | Moduladores del receptor de n-metil-d-aspartato, y usos de los mismos. |
WO2010088409A2 (en) * | 2009-01-30 | 2010-08-05 | Emory University | Methods of neuroprotection using neuroprotective steroids and a vitamin d |
US8951968B2 (en) | 2009-10-05 | 2015-02-10 | Northwestern University | Methods of treating depression and other related diseases |
EP3689364A1 (en) | 2010-02-08 | 2020-08-05 | Shenzhen Evergreen Therapeutics Co., Ltd. | Methods for the use of progestogen as a glucocorticoid sensitizer |
US20110262502A1 (en) * | 2010-02-08 | 2011-10-27 | Prairie Pharmaceuticals LLC | Pulmonary delivery of 17-hydroxyprogesterone caproate (17-hpc) |
US10993879B2 (en) * | 2010-02-08 | 2021-05-04 | Shenzhen Evergreen Therapeutics Co., Ltd. | Pulmonary delivery of progestogen |
US10987361B2 (en) | 2010-02-08 | 2021-04-27 | Shenzhen Evergreen Therapeutics Co., Ltd. | Treating auto-immune and auto-inflammatory diseases |
TW201138782A (en) | 2010-04-26 | 2011-11-16 | Besins Healthcare Lu Sarl | Low-oil pharmaceutical emulsion compositions comprising progestogen |
CA2834286A1 (en) * | 2011-04-27 | 2012-11-01 | Northwestern University | Methods of treating alzheimer's disease, huntington's disease, autism, and other disorders |
WO2013043985A1 (en) | 2011-09-23 | 2013-03-28 | The Regents Of The University Of California | Edible oils to enhance delivery of orally administered steroids |
BR112014018110B1 (pt) * | 2012-01-23 | 2022-06-07 | Sage Therapeutics, Inc | Composições farmacêutica aquosas formuladas para administração parenteral e uso de alopregnanolona e sulfobutiléter-b-ciclodextrina |
US20130210785A1 (en) | 2012-02-15 | 2013-08-15 | Emory University | Progesterone analogs and uses related thereto |
EP2819650A1 (en) | 2012-02-29 | 2015-01-07 | B. Braun Melsungen AG | Hormone containing emulsion comprising krill phospholipids |
RU2498826C1 (ru) * | 2012-05-14 | 2013-11-20 | Федеральное государственное бюджетное учреждение науки Комплексный научно-исследовательский институт им. Х.И. Ибрагимова Российской академии наук | Способ лечения больных с черепно-мозговой травмой |
EP2887944B1 (en) * | 2012-08-21 | 2021-10-06 | Sage Therapeutics, Inc. | Allopregnanolone for treating refractory status epilepticus |
CA2892811A1 (en) | 2012-11-30 | 2014-06-05 | The Regents Of The University Of California | Allopregnanolone and a sulfobutylether-b-cyclodextrin salt for the treatment of post-partum depression |
BR112015018092A2 (pt) | 2013-01-29 | 2017-07-18 | Naurex Inc | moduladores de receptor de nmda de espiro-lactama e usos dos mesmos |
WO2014120800A1 (en) | 2013-01-29 | 2014-08-07 | Naurex, Inc. | Spiro-lactam nmda receptor modulators and uses thereof |
LT3514158T (lt) | 2013-01-29 | 2023-02-10 | Aptinyx Inc. | Spirolaktaminiai nmda receptoriaus moduliatoriai ir jų panaudojimas |
EA201591404A1 (ru) | 2013-01-29 | 2016-01-29 | Аптиникс Инк. | Спиролактамные модуляторы рецептора nmda и их применение |
EA032153B1 (ru) | 2013-01-29 | 2019-04-30 | Аптиникс Инк. | Спиролактамные модуляторы nmda-рецептора и их применение |
DK3033350T3 (da) | 2013-08-12 | 2021-08-30 | Univ Emory | Progesterone fosfatanaloger og anvendelser relateret dertil |
US10231979B2 (en) * | 2015-08-07 | 2019-03-19 | Indiana University Research And Technology Corporation | Modulation of inflammation using progesterone metabolites |
EP3426257A4 (en) | 2016-03-08 | 2019-11-13 | Sage Therapeutics, Inc. | NEUROACTIVE STEROIDS, COMPOSITIONS AND USES THEREOF |
WO2017201285A1 (en) | 2016-05-19 | 2017-11-23 | Aptinyx Inc. | Spiro-lactam nmda receptor modulators and uses thereof |
MX2018014202A (es) | 2016-05-19 | 2019-06-20 | Aptinyx Inc | Moduladores del receptor espiro-lactama n-metil-d-aspartato y usos de los mismos. |
BR112019001923A2 (pt) | 2016-08-01 | 2019-05-14 | Aptinyx Inc. | moduladores de nmda de espiro-lactama e métodos de sua utilização |
AU2017305240B2 (en) | 2016-08-01 | 2021-12-09 | Aptinyx Inc. | Spiro-lactam NMDA receptor modulators and uses thereof |
AU2017306152A1 (en) | 2016-08-01 | 2019-01-31 | Aptinyx Inc. | Spiro-lactam NMDA receptor modulators and uses thereof |
PE20190500A1 (es) | 2016-08-01 | 2019-04-10 | Aptinyx Inc | Moduladores del receptor nmda spiro-lactam y uso de los mismos |
MX2019001322A (es) | 2016-08-01 | 2019-09-11 | Aptinyx Inc | Moduladores del receptor nmda spiro-lactam y bis-spiro-lactam y uso de los mismos. |
JP7210599B2 (ja) | 2018-01-31 | 2023-01-23 | アプティニックス インコーポレイテッド | スピロラクタム系nmda受容体修飾因子およびその使用 |
WO2020180424A1 (en) | 2019-03-04 | 2020-09-10 | Iocurrents, Inc. | Data compression and communication using machine learning |
US12012413B2 (en) | 2019-11-11 | 2024-06-18 | Tenacia Biotechnology (Hong Kong) Co., Limited | Methods of treating painful diabetic peripheral neuropathy |
US20230190709A1 (en) * | 2021-12-02 | 2023-06-22 | MarvelBiome, Inc. | Methods and uses of microbiome compositions, components, or metabolites for treating vagus nerve associated diseases, disorders, and conditions |
WO2024059056A1 (en) * | 2022-09-12 | 2024-03-21 | Emory University | Methods of managing traumatic brain injury |
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US7473687B2 (en) * | 2005-03-24 | 2009-01-06 | Emory University | Methods for the treatment of a traumatic central nervous system injury |
ES2428313T3 (es) * | 2005-03-24 | 2013-11-07 | Emory University | Métodos para el tratamiento de lesiones del sistema nervioso central mediante un protocolo de administración decreciente |
-
2006
- 2006-03-24 ES ES11177154T patent/ES2428313T3/es active Active
- 2006-03-24 WO PCT/US2006/010797 patent/WO2006102596A2/en active Application Filing
- 2006-03-24 PL PL06748657T patent/PL1868614T3/pl unknown
- 2006-03-24 PT PT08167618T patent/PT2030622E/pt unknown
- 2006-03-24 AU AU2006226811A patent/AU2006226811B2/en not_active Ceased
- 2006-03-24 RS RS20120433A patent/RS52471B/en unknown
- 2006-03-24 PT PT06748657T patent/PT1868614E/pt unknown
- 2006-03-24 EP EP06739662A patent/EP1871382B1/en active Active
- 2006-03-24 PL PL08167618T patent/PL2030622T3/pl unknown
- 2006-03-24 US US11/909,276 patent/US20090221544A1/en not_active Abandoned
- 2006-03-24 AT AT06739662T patent/ATE520404T1/de not_active IP Right Cessation
- 2006-03-24 ES ES06748657T patent/ES2392454T3/es active Active
- 2006-03-24 AT AT08167618T patent/ATE499104T1/de active
- 2006-03-24 CA CA2601715A patent/CA2601715C/en not_active Expired - Fee Related
- 2006-03-24 CA CA2602950A patent/CA2602950C/en not_active Expired - Fee Related
- 2006-03-24 JP JP2008503227A patent/JP5295755B2/ja not_active Expired - Fee Related
- 2006-03-24 DK DK06748657.1T patent/DK1868614T3/da active
- 2006-03-24 DK DK08167618.1T patent/DK2030622T3/da active
- 2006-03-24 EP EP12163432A patent/EP2494976A1/en not_active Withdrawn
- 2006-03-24 JP JP2008503262A patent/JP5394059B2/ja not_active Expired - Fee Related
- 2006-03-24 AU AU2006226774A patent/AU2006226774B2/en not_active Ceased
- 2006-03-24 EP EP08167618A patent/EP2030622B1/en active Active
- 2006-03-24 DE DE602006020353T patent/DE602006020353D1/de active Active
- 2006-03-24 WO PCT/US2006/010984 patent/WO2006102644A2/en active Application Filing
- 2006-03-24 EP EP11177154.9A patent/EP2431042B1/en active Active
- 2006-03-24 EP EP06748657A patent/EP1868614B1/en active Active
- 2006-03-24 US US11/909,278 patent/US20090325920A1/en not_active Abandoned
-
2008
- 2008-06-25 HK HK08107067.5A patent/HK1112579A1/xx not_active IP Right Cessation
- 2008-06-30 HK HK08107230.7A patent/HK1112581A1/xx not_active IP Right Cessation
-
2009
- 2009-08-14 HK HK09107489.4A patent/HK1128242A1/xx not_active IP Right Cessation
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2011
- 2011-03-17 HR HR20110198T patent/HRP20110198T1/hr unknown
- 2011-05-20 CY CY20111100496T patent/CY1111478T1/el unknown
- 2011-08-17 JP JP2011178655A patent/JP2011225629A/ja not_active Withdrawn
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2012
- 2012-04-24 US US13/454,503 patent/US20120245133A1/en not_active Abandoned
- 2012-07-16 US US13/550,148 patent/US8614203B2/en active Active
- 2012-08-30 HR HRP20120688TT patent/HRP20120688T1/hr unknown
- 2012-10-25 CY CY20121101012T patent/CY1113253T1/el unknown
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2013
- 2013-07-12 JP JP2013146680A patent/JP2013234191A/ja not_active Withdrawn
- 2013-12-20 JP JP2013263682A patent/JP5496407B2/ja not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20190326 |