WO2006096458A3 - Treatment of hyperproliferative diseases with anthraquinones - Google Patents

Treatment of hyperproliferative diseases with anthraquinones Download PDF

Info

Publication number
WO2006096458A3
WO2006096458A3 PCT/US2006/007452 US2006007452W WO2006096458A3 WO 2006096458 A3 WO2006096458 A3 WO 2006096458A3 US 2006007452 W US2006007452 W US 2006007452W WO 2006096458 A3 WO2006096458 A3 WO 2006096458A3
Authority
WO
WIPO (PCT)
Prior art keywords
anthraquinones
treatment
hyperproliferative diseases
relates
hyperproliferative disorders
Prior art date
Application number
PCT/US2006/007452
Other languages
French (fr)
Other versions
WO2006096458A2 (en
Inventor
Jeffrey L Cleland
Alvin Wong
Original Assignee
Novacea Inc
Jeffrey L Cleland
Alvin Wong
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novacea Inc, Jeffrey L Cleland, Alvin Wong filed Critical Novacea Inc
Priority to EP06736721A priority Critical patent/EP1853243A2/en
Priority to CA002598249A priority patent/CA2598249A1/en
Priority to JP2007558228A priority patent/JP2008531720A/en
Priority to AU2006220886A priority patent/AU2006220886A1/en
Priority to US11/520,034 priority patent/US20070117784A1/en
Publication of WO2006096458A2 publication Critical patent/WO2006096458A2/en
Publication of WO2006096458A3 publication Critical patent/WO2006096458A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

The invention relates to anthraquinone compounds having activity for treating hyperproliferative disorders. Further, the invention relates to methods of using the compounds, alone or in combination with one or more other active agents or treatments, to treat hyperproliferative disorders.
PCT/US2006/007452 2005-03-04 2006-03-03 Treatment of hyperproliferative diseases with anthraquinones WO2006096458A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP06736721A EP1853243A2 (en) 2005-03-04 2006-03-03 Treatment of hyperproliferative diseases with anthraquinones
CA002598249A CA2598249A1 (en) 2005-03-04 2006-03-03 Treatment of hyperproliferative diseases with anthraquinones
JP2007558228A JP2008531720A (en) 2005-03-04 2006-03-03 Treatment of hyperproliferative diseases with anthraquinone
AU2006220886A AU2006220886A1 (en) 2005-03-04 2006-03-03 Treatment of hyperproliferative diseases with anthraquinones
US11/520,034 US20070117784A1 (en) 2005-03-04 2006-09-13 Treatment of hyperproliferative diseases with anthraquinones

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65837105P 2005-03-04 2005-03-04
US60/658,371 2005-03-04

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/520,034 Continuation-In-Part US20070117784A1 (en) 2005-03-04 2006-09-13 Treatment of hyperproliferative diseases with anthraquinones

Publications (2)

Publication Number Publication Date
WO2006096458A2 WO2006096458A2 (en) 2006-09-14
WO2006096458A3 true WO2006096458A3 (en) 2007-12-13

Family

ID=36953858

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/007452 WO2006096458A2 (en) 2005-03-04 2006-03-03 Treatment of hyperproliferative diseases with anthraquinones

Country Status (6)

Country Link
EP (1) EP1853243A2 (en)
JP (1) JP2008531720A (en)
CN (1) CN101193644A (en)
AU (1) AU2006220886A1 (en)
CA (1) CA2598249A1 (en)
WO (1) WO2006096458A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110287112A1 (en) * 2009-01-30 2011-11-24 Ono Pharmaceutical Co., Ltd. Prostate cancer progression inhibitor and progression inhibition method
GB201214169D0 (en) 2012-08-08 2012-09-19 Biostatus Ltd New compounds and uses thereof
CN107184563A (en) * 2017-05-31 2017-09-22 潘小平 Micro-capsule, the preparation method and use of Physcion and its derivative

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4604463A (en) * 1983-07-14 1986-08-05 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
US5132327A (en) * 1989-10-13 1992-07-21 National Research Development Corporation Anti-cancer compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4604463A (en) * 1983-07-14 1986-08-05 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
US5132327A (en) * 1989-10-13 1992-07-21 National Research Development Corporation Anti-cancer compounds

Also Published As

Publication number Publication date
JP2008531720A (en) 2008-08-14
CN101193644A (en) 2008-06-04
EP1853243A2 (en) 2007-11-14
CA2598249A1 (en) 2006-09-14
AU2006220886A1 (en) 2006-09-14
WO2006096458A2 (en) 2006-09-14

Similar Documents

Publication Publication Date Title
WO2008033440A3 (en) Treatment of hyperproliferative diseases with anthraquinones
WO2007098089A3 (en) Treatment of hyperproliferative diseases with methotrexate n-oxide and analogs
GB2442915B (en) Perylenequinone derivatives and uses thereof
TW200740804A (en) Glucokinase activators
WO2007098091A3 (en) Treatment of hyperproliferative diseases with vinca alkaloid n-oxide and analogs
WO2005116088A3 (en) Methods and compositions for treating diseases and disorders associated with siglec-8 expressing cells
ATE521608T1 (en) GLUCOKINASE ACTIVATORS
WO2007117381A3 (en) 2 -aminopyridine analogs as glucokinase activators
MX2007010560A (en) Roflumilast for the treatment of diabetes mellitus.
WO2007127505A3 (en) Use of sulfonamide derivatives in the treatment of disorders of the metabolism and the nervous system
WO2008118718A3 (en) 2-aminopyridine analogs as glucokinase activators
WO2006124913A3 (en) Compositions and methods for the treatment of disorders of the central and peripheral nervous systems
WO2007076161A3 (en) Compounds with therapeutic activity
WO2009045464A8 (en) Methods of treating neurological autoimmune disorders with cyclophosphamide
WO2006020680A3 (en) Heterocyclic compounds as pharmaceutical agents
WO2004096216A3 (en) Use of a topical medicament comprising riluzole
WO2008029169A3 (en) Method of treating respiratory disorders
WO2006086693A3 (en) Medical devices
WO2007136741A3 (en) N-desmethyl-doxepin and methods of using the same to treat sleep disorders
WO2008157747A8 (en) Use of inhibition of exonuclease 1 in methods for therapy and diagnostic of neurodegenerative diseases, eye diseases, and mitochondrial disorders
WO2007130501A3 (en) Combination therapy for treatment of cancer
HK1102626A1 (en) Compositions and methods for the treatment and prevention of hyperproliferative diseases
WO2008155390A3 (en) Use of inhibitors of sirtuins and/or ampk for the preparation of a medicament for the treatment of polyalanine diseases.
ZA200609220B (en) Method of treating dry eye disorders and uveitis
WO2006096458A3 (en) Treatment of hyperproliferative diseases with anthraquinones

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200680006584.7

Country of ref document: CN

WWE Wipo information: entry into national phase

Ref document number: 11520034

Country of ref document: US

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWP Wipo information: published in national office

Ref document number: 11520034

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 2006220886

Country of ref document: AU

ENP Entry into the national phase

Ref document number: 2598249

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2006736721

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2007558228

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

ENP Entry into the national phase

Ref document number: 2006220886

Country of ref document: AU

Date of ref document: 20060303

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: RU