PL1868614T3 - Schemat dawkowania do leczenia urazowego uszkodzenia mózgu progesteronem - Google Patents
Schemat dawkowania do leczenia urazowego uszkodzenia mózgu progesteronemInfo
- Publication number
- PL1868614T3 PL1868614T3 PL06748657T PL06748657T PL1868614T3 PL 1868614 T3 PL1868614 T3 PL 1868614T3 PL 06748657 T PL06748657 T PL 06748657T PL 06748657 T PL06748657 T PL 06748657T PL 1868614 T3 PL1868614 T3 PL 1868614T3
- Authority
- PL
- Poland
- Prior art keywords
- progesterone
- treatment
- brain injury
- dosage regimen
- traumatic brain
- Prior art date
Links
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 title abstract 5
- 229960003387 progesterone Drugs 0.000 title abstract 2
- 239000000186 progesterone Substances 0.000 title abstract 2
- 208000030886 Traumatic Brain injury Diseases 0.000 title 1
- 230000009529 traumatic brain injury Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 4
- 208000001738 Nervous System Trauma Diseases 0.000 abstract 3
- 210000003169 central nervous system Anatomy 0.000 abstract 3
- 208000028412 nervous system injury Diseases 0.000 abstract 3
- 206010030113 Oedema Diseases 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 230000016273 neuron death Effects 0.000 abstract 1
- 239000000583 progesterone congener Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66472805P | 2005-03-24 | 2005-03-24 | |
| US72966305P | 2005-10-24 | 2005-10-24 | |
| PCT/US2006/010797 WO2006102596A2 (en) | 2005-03-24 | 2006-03-24 | Dosage regimen for the treatment of a traumatic brain injury with progesterone |
| EP06748657A EP1868614B1 (en) | 2005-03-24 | 2006-03-24 | Dosage regimen for the treatment of a traumatic brain injury with progesterone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1868614T3 true PL1868614T3 (pl) | 2013-01-31 |
Family
ID=36987966
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08167618T PL2030622T3 (pl) | 2005-03-24 | 2006-03-24 | Wskazanie dawkowania progesteronu w leczeniu urazowego uszkodzenia mózgu |
| PL06748657T PL1868614T3 (pl) | 2005-03-24 | 2006-03-24 | Schemat dawkowania do leczenia urazowego uszkodzenia mózgu progesteronem |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08167618T PL2030622T3 (pl) | 2005-03-24 | 2006-03-24 | Wskazanie dawkowania progesteronu w leczeniu urazowego uszkodzenia mózgu |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US20090325920A1 (pl) |
| EP (5) | EP2030622B1 (pl) |
| JP (5) | JP5394059B2 (pl) |
| AT (2) | ATE520404T1 (pl) |
| AU (2) | AU2006226811B2 (pl) |
| CA (2) | CA2602950C (pl) |
| CY (2) | CY1111478T1 (pl) |
| DE (1) | DE602006020353D1 (pl) |
| DK (2) | DK1868614T3 (pl) |
| ES (2) | ES2428313T3 (pl) |
| HR (2) | HRP20120688T1 (pl) |
| PL (2) | PL2030622T3 (pl) |
| PT (2) | PT1868614E (pl) |
| RS (1) | RS52471B (pl) |
| WO (2) | WO2006102596A2 (pl) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1868614E (pt) * | 2005-03-24 | 2012-11-23 | Univ Emory | Regime de dosagem para o tratamento de uma lesão cerebral traumática com progesterona |
| US7473687B2 (en) * | 2005-03-24 | 2009-01-06 | Emory University | Methods for the treatment of a traumatic central nervous system injury |
| EP2052724A1 (en) * | 2007-10-26 | 2009-04-29 | sanofi-aventis | Use of norgestimate as a selective inhibitor of TRPC3, TRPC6 and TRPC6 and TRPC7 ion channel |
| CA2955684A1 (en) | 2008-02-26 | 2009-09-03 | Emory University | Steroid analogues for neuroprotection |
| RU2366466C1 (ru) * | 2008-03-25 | 2009-09-10 | Олег Васильевич Онысько | Способ лечения черепно-мозговой травмы |
| BRPI0918868B8 (pt) | 2008-09-18 | 2021-05-25 | Naurex Inc | compostos moduladores do receptor de nmda e composições compreendendo os mesmos |
| WO2010088409A2 (en) * | 2009-01-30 | 2010-08-05 | Emory University | Methods of neuroprotection using neuroprotective steroids and a vitamin d |
| US8951968B2 (en) | 2009-10-05 | 2015-02-10 | Northwestern University | Methods of treating depression and other related diseases |
| US10987361B2 (en) | 2010-02-08 | 2021-04-27 | Shenzhen Evergreen Therapeutics Co., Ltd. | Treating auto-immune and auto-inflammatory diseases |
| WO2011097571A2 (en) | 2010-02-08 | 2011-08-11 | Prairie Pharmaceuticals, Llc | Methods for the use of progestogen as a glucocorticoid sensitizer |
| US10993879B2 (en) * | 2010-02-08 | 2021-05-04 | Shenzhen Evergreen Therapeutics Co., Ltd. | Pulmonary delivery of progestogen |
| US20110262502A1 (en) * | 2010-02-08 | 2011-10-27 | Prairie Pharmaceuticals LLC | Pulmonary delivery of 17-hydroxyprogesterone caproate (17-hpc) |
| TW201138782A (en) | 2010-04-26 | 2011-11-16 | Besins Healthcare Lu Sarl | Low-oil pharmaceutical emulsion compositions comprising progestogen |
| KR20140043078A (ko) * | 2011-04-27 | 2014-04-08 | 노오쓰웨스턴 유니버시티 | 알츠하이머병, 헌팅톤병, 자폐증 또는 기타 장애의 치료 방법 |
| WO2013043985A1 (en) | 2011-09-23 | 2013-03-28 | The Regents Of The University Of California | Edible oils to enhance delivery of orally administered steroids |
| CA2862076C (en) * | 2012-01-23 | 2020-04-21 | Sage Therapeutics, Inc. | Neuroactive steroid formulations and methods of treating cns disorders |
| US20130210785A1 (en) | 2012-02-15 | 2013-08-15 | Emory University | Progesterone analogs and uses related thereto |
| JP2015508791A (ja) | 2012-02-29 | 2015-03-23 | ビー.ブラウン メルズンゲン アーゲーB.Braun Melsungen Ag | オキアミリン脂質を含むホルモン含有乳剤 |
| RU2498826C1 (ru) * | 2012-05-14 | 2013-11-20 | Федеральное государственное бюджетное учреждение науки Комплексный научно-исследовательский институт им. Х.И. Ибрагимова Российской академии наук | Способ лечения больных с черепно-мозговой травмой |
| WO2014031792A2 (en) | 2012-08-21 | 2014-02-27 | Sage Therapeutics | Methods of treating epilepsy or tatus epilepticus |
| DK2925327T3 (da) | 2012-11-30 | 2024-03-25 | Univ California | Allopregnanolon til behandling, reduktion eller lindring af symptomer på fødselsdepression |
| CA2898863A1 (en) | 2013-01-29 | 2014-08-07 | Naurex, Inc. | Spiro-lactam nmda receptor modulators and uses thereof |
| PH12015501596B1 (en) | 2013-01-29 | 2023-12-06 | Aptinyx Inc | Spiro-lactam nmda receptor modulators and uses thereof |
| CA2898861C (en) | 2013-01-29 | 2021-07-20 | Naurex, Inc. | Spiro-lactam nmda receptor modulators and uses thereof |
| CN105026401A (zh) | 2013-01-29 | 2015-11-04 | 诺雷克斯股份有限公司 | 螺-内酰胺nmda受体调节剂及其用途 |
| WO2014120800A1 (en) | 2013-01-29 | 2014-08-07 | Naurex, Inc. | Spiro-lactam nmda receptor modulators and uses thereof |
| EP3033350B1 (en) | 2013-08-12 | 2021-07-28 | Emory University | Progesterone phosphate analogs and uses related thereto |
| JOP20200195A1 (ar) | 2014-09-08 | 2017-06-16 | Sage Therapeutics Inc | سترويدات وتركيبات نشطة عصبياً، واستخداماتها |
| US10231979B2 (en) * | 2015-08-07 | 2019-03-19 | Indiana University Research And Technology Corporation | Modulation of inflammation using progesterone metabolites |
| HK1258616A1 (zh) | 2016-03-08 | 2019-11-15 | Sage Therapeutics, Inc. | 神经活性类固醇、组合物、及其用途 |
| WO2017201285A1 (en) | 2016-05-19 | 2017-11-23 | Aptinyx Inc. | Spiro-lactam nmda receptor modulators and uses thereof |
| EA201892657A1 (ru) | 2016-05-19 | 2019-05-31 | Аптиникс Инк. | Спиролактамовые модуляторы nmda-рецептора и их применение |
| WO2018026792A1 (en) | 2016-08-01 | 2018-02-08 | Aptinyx Inc. | Spiro-lactam and bis-spiro-lactam nmda receptor modulators and uses thereof |
| IL286107B2 (en) | 2016-08-01 | 2024-09-01 | Aptinyx Inc | Spiro-lactam nmda receptor modulators and usesthereof |
| US10961189B2 (en) | 2016-08-01 | 2021-03-30 | Aptinyx Inc. | Spiro-lactam NMDA receptor modulators and uses thereof |
| CA3031537A1 (en) | 2016-08-01 | 2018-02-08 | Aptinyx Inc. | Spiro-lactam nmda receptor modulators and uses thereof |
| CN109843889B (zh) | 2016-08-01 | 2022-03-15 | 阿普廷伊克斯股份有限公司 | 螺-内酰胺nmda调节剂和使用其的方法 |
| US11578072B2 (en) | 2018-01-31 | 2023-02-14 | Aptinyx Inc. | Spiro-lactam NMDA receptor modulators and uses thereof |
| WO2020157206A1 (en) * | 2019-01-31 | 2020-08-06 | University Of Geneva | Prospective markers in traumatic brain injury (tbi) |
| US11216742B2 (en) | 2019-03-04 | 2022-01-04 | Iocurrents, Inc. | Data compression and communication using machine learning |
| US12012413B2 (en) | 2019-11-11 | 2024-06-18 | Tenacia Biotechnology (Hong Kong) Co., Limited | Methods of treating painful diabetic peripheral neuropathy |
| EP4440342A4 (en) * | 2021-12-02 | 2026-03-11 | Marvelbiome Inc | METHODS AND USES OF MICROBIOME COMPOSITIONS, COMPONENTS OR METABOLITES FOR THE TREATMENT OF DISEASES, DISORDERS AND CONDITIONS ASSOCIATED WITH THE VAGUE NERVE |
| US20230293722A1 (en) * | 2022-01-05 | 2023-09-21 | Metaqor Llc | Compositions and Methods for Treating Neurological-associated Disorders |
| WO2024059056A1 (en) * | 2022-09-12 | 2024-03-21 | Emory University | Methods of managing traumatic brain injury |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5217085A (en) | 1975-07-30 | 1977-02-08 | Ono Pharmaceut Co Ltd | Method of quantitative determination of free fatty acids in serum usin g fatty acid activating enzymes |
| US4404366A (en) * | 1980-05-06 | 1983-09-13 | Miles Laboratories, Inc. | Beta-galactosyl-umbelliferone-labeled hapten conjugates |
| US4369250A (en) | 1981-07-31 | 1983-01-18 | Sherwood Medical Industries Inc. | Fatty acid determination |
| USRE35517E (en) * | 1987-08-25 | 1997-05-20 | University Of Southern California | Method, compositions, and compounds for modulating brain excitability |
| US5120723A (en) * | 1987-08-25 | 1992-06-09 | University Of Southern California | Method, compositions, and compounds for modulating brain excitability |
| US5232917A (en) * | 1987-08-25 | 1993-08-03 | University Of Southern California | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series |
| EP0382790A4 (en) | 1987-08-25 | 1991-03-27 | Kelvin W. Gee | Compositions and methods for alleviating stress, anxiety and seizure activity |
| US5512429A (en) | 1989-09-19 | 1996-04-30 | British Technology Group Limited | Assay for enzyme activity |
| GB9105707D0 (en) | 1991-03-18 | 1991-05-01 | Wilton David C | Assay |
| US5114388A (en) * | 1991-07-26 | 1992-05-19 | True Fitness Technology, Inc. | Stair simulator exerciser with adjustable incline |
| US5212167A (en) * | 1991-09-12 | 1993-05-18 | Trustees Of Boston University | Modulation of receptor-mediated ion transport |
| US5206415A (en) * | 1991-12-20 | 1993-04-27 | Washington University | Tricyclic steroid analogs |
| SK286051B6 (sk) * | 1993-01-19 | 2008-02-05 | Endorecherche Inc. | Použitie prekurzora pohlavného steroidu na prípravu liečiva na prevenciu alebo liečenie znížených alebo nevyrovnaných koncentrácií pohlavných steroidov |
| US5776923A (en) * | 1993-01-19 | 1998-07-07 | Endorecherche, Inc. | Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone |
| DE4311870C2 (de) | 1993-04-10 | 1998-07-30 | Altramed Holdings Ltd | Verwendung eines Anti-Östrigens zur Therapie und Prophylaxe von Demenz-Erkrankungen |
| US5763431A (en) * | 1993-08-20 | 1998-06-09 | Jackson; Meyer B. | Method for regulating neuropeptide hormone secretion |
| AU7569194A (en) * | 1993-08-20 | 1995-03-21 | Meyer B. Jackson | Method for regulating neuropeptide hormone secretion |
| US5939545A (en) * | 1994-02-14 | 1999-08-17 | Cocensys, Inc. | Method, compositions, and compounds for allosteric modulation of the gaba receptor by members of the androstane and pregnane series |
| US5633011A (en) * | 1994-08-04 | 1997-05-27 | Alza Corporation | Progesterone replacement therapy |
| US5767117A (en) * | 1994-11-18 | 1998-06-16 | The General Hospital Corporation | Method for treating vascular headaches |
| FR2727117A1 (fr) * | 1994-11-18 | 1996-05-24 | Geffard Michel | Utilisation de conjugues de la polylysine pour la preparation de medicaments utiles dans le traitement des maladies neurodegeneratives et des affections degeneratives a caractere autoimmun |
| US6077947A (en) * | 1995-02-02 | 2000-06-20 | Cell Genesys, Inc. | DNA encoding an intracellular chimeric receptor comprising Janus kinase |
| ATE284895T1 (de) * | 1995-06-06 | 2005-01-15 | Euro Celtique Sa | Neuroaktive steroide der androstan- und pregnanreihe |
| ATE267587T1 (de) * | 1995-06-09 | 2004-06-15 | Euro Celtique Sa | Formulierungen und verfahren für eine verlängerte lokalanästhesie |
| US5888996A (en) * | 1995-07-26 | 1999-03-30 | Trustees Of Boston University | Inhibition of NMDA receptor activity and modulation of glutamate-mediated synaptic activity |
| CA2256365A1 (en) | 1996-05-22 | 1997-11-27 | Diversified Pharmaceuticals, Inc. | Compositions, methods and devices for the transdermal delivery of drugs |
| US5763492A (en) * | 1996-10-01 | 1998-06-09 | Duguesne University Of The Holy Ghost | Methods for effecting memory enhancement mediated by non-steroidal sulfatase inhibitors |
| CA2289006A1 (en) | 1997-05-02 | 1998-11-12 | American Home Products Corporation | Pregnan-3-ol-20-ones |
| US6245757B1 (en) * | 1997-10-03 | 2001-06-12 | Research Corporation Technologies, Inc. | Use of progestins to treat ischemic event |
| US6174547B1 (en) * | 1999-07-14 | 2001-01-16 | Alza Corporation | Dosage form comprising liquid formulation |
| US6268223B1 (en) | 1999-08-27 | 2001-07-31 | Viatech Imagin, Llc | Assay for detecting damage to the central nervous system |
| US20020072509A1 (en) * | 2000-10-11 | 2002-06-13 | Stein Donald Gerald | Methods for the treatment of a traumatic central nervous system injury |
| PT1868614E (pt) * | 2005-03-24 | 2012-11-23 | Univ Emory | Regime de dosagem para o tratamento de uma lesão cerebral traumática com progesterona |
| US7473687B2 (en) * | 2005-03-24 | 2009-01-06 | Emory University | Methods for the treatment of a traumatic central nervous system injury |
-
2006
- 2006-03-24 PT PT06748657T patent/PT1868614E/pt unknown
- 2006-03-24 AU AU2006226811A patent/AU2006226811B2/en not_active Ceased
- 2006-03-24 EP EP08167618A patent/EP2030622B1/en not_active Expired - Lifetime
- 2006-03-24 AT AT06739662T patent/ATE520404T1/de not_active IP Right Cessation
- 2006-03-24 JP JP2008503262A patent/JP5394059B2/ja not_active Expired - Fee Related
- 2006-03-24 PT PT08167618T patent/PT2030622E/pt unknown
- 2006-03-24 DK DK06748657.1T patent/DK1868614T3/da active
- 2006-03-24 DK DK08167618.1T patent/DK2030622T3/da active
- 2006-03-24 WO PCT/US2006/010797 patent/WO2006102596A2/en not_active Ceased
- 2006-03-24 US US11/909,278 patent/US20090325920A1/en not_active Abandoned
- 2006-03-24 US US11/909,276 patent/US20090221544A1/en not_active Abandoned
- 2006-03-24 EP EP06739662A patent/EP1871382B1/en not_active Expired - Lifetime
- 2006-03-24 EP EP11177154.9A patent/EP2431042B1/en not_active Expired - Lifetime
- 2006-03-24 CA CA2602950A patent/CA2602950C/en not_active Expired - Fee Related
- 2006-03-24 AU AU2006226774A patent/AU2006226774B2/en not_active Ceased
- 2006-03-24 EP EP06748657A patent/EP1868614B1/en not_active Expired - Lifetime
- 2006-03-24 PL PL08167618T patent/PL2030622T3/pl unknown
- 2006-03-24 PL PL06748657T patent/PL1868614T3/pl unknown
- 2006-03-24 WO PCT/US2006/010984 patent/WO2006102644A2/en not_active Ceased
- 2006-03-24 DE DE602006020353T patent/DE602006020353D1/de not_active Expired - Lifetime
- 2006-03-24 CA CA2601715A patent/CA2601715C/en not_active Expired - Fee Related
- 2006-03-24 HR HRP20120688TT patent/HRP20120688T1/hr unknown
- 2006-03-24 ES ES11177154T patent/ES2428313T3/es not_active Expired - Lifetime
- 2006-03-24 RS RS20120433A patent/RS52471B/sr unknown
- 2006-03-24 EP EP12163432A patent/EP2494976A1/en not_active Withdrawn
- 2006-03-24 AT AT08167618T patent/ATE499104T1/de active
- 2006-03-24 JP JP2008503227A patent/JP5295755B2/ja not_active Expired - Fee Related
- 2006-03-24 ES ES06748657T patent/ES2392454T3/es not_active Expired - Lifetime
-
2011
- 2011-03-17 HR HR20110198T patent/HRP20110198T1/hr unknown
- 2011-05-20 CY CY20111100496T patent/CY1111478T1/el unknown
- 2011-08-17 JP JP2011178655A patent/JP2011225629A/ja not_active Withdrawn
-
2012
- 2012-04-24 US US13/454,503 patent/US20120245133A1/en not_active Abandoned
- 2012-07-16 US US13/550,148 patent/US8614203B2/en not_active Expired - Fee Related
- 2012-10-25 CY CY20121101012T patent/CY1113253T1/el unknown
-
2013
- 2013-07-12 JP JP2013146680A patent/JP2013234191A/ja not_active Withdrawn
- 2013-12-20 JP JP2013263682A patent/JP5496407B2/ja not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL1868614T3 (pl) | Schemat dawkowania do leczenia urazowego uszkodzenia mózgu progesteronem | |
| WO2008039898A3 (en) | Methods for the treatment of a traumatic central nervous system injury | |
| Deutsch et al. | Progesterone's role in neuroprotection, a review of the evidence | |
| MX2020008680A (es) | Terapia de combinacion con apilimod y agentes glutamatergicos. | |
| WO2016025635A3 (en) | Combination therapy for treating cancer | |
| EP4269439A3 (en) | Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns | |
| WO2012106444A3 (en) | Methods, devices and systems for treating insomnia by inducing frontal cerebral hypothermia | |
| EP1648385A4 (en) | SYSTEM AND METHOD FOR THE PHOTODYNAMIC TREATMENT OF COMBUSTIONS, WOUNDS AND RELATED SKIN DISEASES | |
| WO2009126931A3 (en) | Therapy for bipolar disorder and mania with buprenorphine | |
| WO2005070052A3 (en) | Use of photodynamic therapy to enhance treatment with immuno-modulating agents | |
| FI3370760T3 (fi) | Plasminogeenivajauksen plasminogeenikorvaushoito | |
| MY202377A (en) | Treating gastric cancer using combination therapies comprising liposomal irinotecan, oxaliplatin, 5-fluorouracil (and leucovorin) | |
| PH12018502134A1 (en) | Methods of treating pediatric cancers | |
| WO2016043874A3 (en) | Combination therapy for treating cancer | |
| WO2003092617A3 (en) | Combinations for the treatment of inflammatory skin disorders | |
| WO2004012662A3 (en) | Improved treatment of cancer with glutamine | |
| WO2017042633A3 (en) | Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns | |
| WO2008033440A3 (en) | Treatment of hyperproliferative diseases with anthraquinones | |
| SI1913947T1 (sl) | Kombinirana terapija za zdravljenje raka | |
| WO2005118601A3 (en) | Sulfonylethyl phosphorodiamidates for use in the treatment of cancer | |
| WO2007134203A3 (en) | Anticancer treatments with a combination of docetaxel and ecteinascidin | |
| PL1704860T3 (pl) | Pochodne benzamidyny do leczenia i zapobiegania zapaleniu śluzówki | |
| MX2019001337A (es) | Métodos para tratar y prevenir efectos secundarios por tratamiento de cáncer. | |
| Axelrod et al. | The combination of entospletinib and vincristine demonstrates synergistic activity in a broad panel of hematological cancer cell lines and anti-tumor efficacy in a DLBCL xenograft model | |
| WO2006096458A3 (en) | Treatment of hyperproliferative diseases with anthraquinones |