ATE520404T1 - Verfahren zur behandlung einer verletzung des zentralen nervensystems durch ausschleichende verabreichung von progesteron - Google Patents
Verfahren zur behandlung einer verletzung des zentralen nervensystems durch ausschleichende verabreichung von progesteronInfo
- Publication number
- ATE520404T1 ATE520404T1 AT06739662T AT06739662T ATE520404T1 AT E520404 T1 ATE520404 T1 AT E520404T1 AT 06739662 T AT06739662 T AT 06739662T AT 06739662 T AT06739662 T AT 06739662T AT E520404 T1 ATE520404 T1 AT E520404T1
- Authority
- AT
- Austria
- Prior art keywords
- nervous system
- central nervous
- system injury
- progesterone
- teader
- Prior art date
Links
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 5
- 208000001738 Nervous System Trauma Diseases 0.000 title abstract 4
- 210000003169 central nervous system Anatomy 0.000 title abstract 4
- 208000028412 nervous system injury Diseases 0.000 title abstract 4
- 229960003387 progesterone Drugs 0.000 title abstract 2
- 239000000186 progesterone Substances 0.000 title abstract 2
- 206010030113 Oedema Diseases 0.000 abstract 1
- 230000008030 elimination Effects 0.000 abstract 1
- 238000003379 elimination reaction Methods 0.000 abstract 1
- 208000028867 ischemia Diseases 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 230000016273 neuron death Effects 0.000 abstract 1
- 239000000583 progesterone congener Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66472805P | 2005-03-24 | 2005-03-24 | |
US72966305P | 2005-10-24 | 2005-10-24 | |
PCT/US2006/010984 WO2006102644A2 (en) | 2005-03-24 | 2006-03-24 | Methods for the treatment of central nervous system injury via a tapered administration of progesterone |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE520404T1 true ATE520404T1 (de) | 2011-09-15 |
Family
ID=36987966
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06739662T ATE520404T1 (de) | 2005-03-24 | 2006-03-24 | Verfahren zur behandlung einer verletzung des zentralen nervensystems durch ausschleichende verabreichung von progesteron |
AT08167618T ATE499104T1 (de) | 2005-03-24 | 2006-03-24 | Progesterone dosierungsanweisung in der behandlung einer traumatischen verletzung des gehirns |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT08167618T ATE499104T1 (de) | 2005-03-24 | 2006-03-24 | Progesterone dosierungsanweisung in der behandlung einer traumatischen verletzung des gehirns |
Country Status (16)
Country | Link |
---|---|
US (4) | US20090221544A1 (de) |
EP (5) | EP1871382B1 (de) |
JP (5) | JP5394059B2 (de) |
AT (2) | ATE520404T1 (de) |
AU (2) | AU2006226811B2 (de) |
CA (2) | CA2601715C (de) |
CY (2) | CY1111478T1 (de) |
DE (1) | DE602006020353D1 (de) |
DK (2) | DK1868614T3 (de) |
ES (2) | ES2428313T3 (de) |
HK (3) | HK1112579A1 (de) |
HR (2) | HRP20110198T1 (de) |
PL (2) | PL2030622T3 (de) |
PT (2) | PT2030622E (de) |
RS (1) | RS52471B (de) |
WO (2) | WO2006102596A2 (de) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7473687B2 (en) * | 2005-03-24 | 2009-01-06 | Emory University | Methods for the treatment of a traumatic central nervous system injury |
ES2428313T3 (es) | 2005-03-24 | 2013-11-07 | Emory University | Métodos para el tratamiento de lesiones del sistema nervioso central mediante un protocolo de administración decreciente |
EP2052724A1 (de) | 2007-10-26 | 2009-04-29 | sanofi-aventis | Verwendung von Norgestimat als selektivem Hemmer der Ionenkanäle TRPC3, TRPC6 sowie TRPC6 und TRPC7 |
WO2009108804A2 (en) | 2008-02-26 | 2009-09-03 | Emory University | Steroid analogues for neuroprotection |
ES2553968T3 (es) | 2008-09-18 | 2015-12-15 | Northwestern University | Moduladores del receptor NMDA y sus usos |
US20110306579A1 (en) * | 2009-01-30 | 2011-12-15 | Emory University | Methods of neuroprotection using neuroprotective steroids and a vitamin d |
US8951968B2 (en) | 2009-10-05 | 2015-02-10 | Northwestern University | Methods of treating depression and other related diseases |
US20110262502A1 (en) * | 2010-02-08 | 2011-10-27 | Prairie Pharmaceuticals LLC | Pulmonary delivery of 17-hydroxyprogesterone caproate (17-hpc) |
US10993879B2 (en) * | 2010-02-08 | 2021-05-04 | Shenzhen Evergreen Therapeutics Co., Ltd. | Pulmonary delivery of progestogen |
US10987361B2 (en) | 2010-02-08 | 2021-04-27 | Shenzhen Evergreen Therapeutics Co., Ltd. | Treating auto-immune and auto-inflammatory diseases |
WO2011097571A2 (en) | 2010-02-08 | 2011-08-11 | Prairie Pharmaceuticals, Llc | Methods for the use of progestogen as a glucocorticoid sensitizer |
TW201138782A (en) | 2010-04-26 | 2011-11-16 | Besins Healthcare Lu Sarl | Low-oil pharmaceutical emulsion compositions comprising progestogen |
KR20190037359A (ko) * | 2011-04-27 | 2019-04-05 | 노오쓰웨스턴 유니버시티 | 알츠하이머병, 헌팅톤병, 자폐증 또는 기타 장애의 치료 방법 |
WO2013043985A1 (en) | 2011-09-23 | 2013-03-28 | The Regents Of The University Of California | Edible oils to enhance delivery of orally administered steroids |
CN112472814A (zh) * | 2012-01-23 | 2021-03-12 | 萨奇治疗股份有限公司 | 神经活性类固醇制剂和治疗中枢神经系统障碍的方法 |
US20130210785A1 (en) | 2012-02-15 | 2013-08-15 | Emory University | Progesterone analogs and uses related thereto |
EP2819650A1 (de) | 2012-02-29 | 2015-01-07 | B. Braun Melsungen AG | Hormonhaltige emulsion mit krillphospholipiden |
RU2498826C1 (ru) * | 2012-05-14 | 2013-11-20 | Федеральное государственное бюджетное учреждение науки Комплексный научно-исследовательский институт им. Х.И. Ибрагимова Российской академии наук | Способ лечения больных с черепно-мозговой травмой |
RU2667010C2 (ru) * | 2012-08-21 | 2018-09-13 | Сейдж Терапьютикс, Инк. | Способы лечения эпилепсии или эпилептического статуса |
EP4335505A3 (de) | 2012-11-30 | 2024-06-05 | The Regents of The University of California | Antikonvulsive aktivität von steroiden |
MX2015009772A (es) | 2013-01-29 | 2016-05-31 | Aptinyx Inc | Moduladores de receptores nmda de espiro-lactama y sus usos. |
CN105026401A (zh) | 2013-01-29 | 2015-11-04 | 诺雷克斯股份有限公司 | 螺-内酰胺nmda受体调节剂及其用途 |
CN105229010A (zh) | 2013-01-29 | 2016-01-06 | 阿普廷伊克斯股份有限公司 | 螺-内酰胺nmda受体调节剂及其用途 |
US9708335B2 (en) | 2013-01-29 | 2017-07-18 | Apytinyx Inc. | Spiro-lactam NMDA receptor modulators and uses thereof |
KR102280616B1 (ko) | 2013-01-29 | 2021-07-21 | 앱티닉스 인크. | 스피로-락탐 nmda 수용체 조절인자 및 그의 용도 |
US9802978B2 (en) | 2013-08-12 | 2017-10-31 | Emory University | Progesterone phosphate analogs and uses related thereto |
US10231979B2 (en) * | 2015-08-07 | 2019-03-19 | Indiana University Research And Technology Corporation | Modulation of inflammation using progesterone metabolites |
CN109414444A (zh) | 2016-03-08 | 2019-03-01 | 萨奇治疗股份有限公司 | 神经活性类固醇、其组合物及用途 |
WO2017201285A1 (en) | 2016-05-19 | 2017-11-23 | Aptinyx Inc. | Spiro-lactam nmda receptor modulators and uses thereof |
CA3024606C (en) | 2016-05-19 | 2019-09-03 | Aptinyx Inc. | Spiro-lactam nmda receptor modulators and uses thereof |
AU2017305240B2 (en) | 2016-08-01 | 2021-12-09 | Aptinyx Inc. | Spiro-lactam NMDA receptor modulators and uses thereof |
SG11201900558RA (en) | 2016-08-01 | 2019-02-27 | Aptinyx Inc | Spiro-lactam nmda receptor modulators and uses thereof |
SG10202101055VA (en) | 2016-08-01 | 2021-03-30 | Aptinyx Inc | Spiro-lactam nmda receptor modulators and uses thereof |
CN109661398B (zh) | 2016-08-01 | 2022-07-05 | 阿普廷伊克斯股份有限公司 | 螺-内酰胺和二-螺-内酰胺nmda受体调节剂及其用途 |
WO2018026798A1 (en) | 2016-08-01 | 2018-02-08 | Aptinyx Inc. | Spiro-lactam nmda modulators and methods of using same |
MX2020008107A (es) | 2018-01-31 | 2020-09-25 | Aptinyx Inc | Moduladores del receptor nmda espiro-lactama y usos de los mismos. |
EP3935581A4 (de) | 2019-03-04 | 2022-11-30 | Iocurrents, Inc. | Datenkompression und -kommunikation mit maschinenlernung |
US12012413B2 (en) | 2019-11-11 | 2024-06-18 | Tenacia Biotechnology (Hong Kong) Co., Limited | Methods of treating painful diabetic peripheral neuropathy |
WO2023102149A1 (en) * | 2021-12-02 | 2023-06-08 | MarvelBiome, Inc. | Methods and uses of microbiome compositions, components, or metabolites for treating vagus nerve associated diseases, disorders, and conditions |
WO2024059056A1 (en) * | 2022-09-12 | 2024-03-21 | Emory University | Methods of managing traumatic brain injury |
Family Cites Families (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5217085A (en) | 1975-07-30 | 1977-02-08 | Ono Pharmaceut Co Ltd | Method of quantitative determination of free fatty acids in serum usin g fatty acid activating enzymes |
US4404366A (en) * | 1980-05-06 | 1983-09-13 | Miles Laboratories, Inc. | Beta-galactosyl-umbelliferone-labeled hapten conjugates |
US4369250A (en) | 1981-07-31 | 1983-01-18 | Sherwood Medical Industries Inc. | Fatty acid determination |
USRE35517E (en) * | 1987-08-25 | 1997-05-20 | University Of Southern California | Method, compositions, and compounds for modulating brain excitability |
EP0382790A4 (en) | 1987-08-25 | 1991-03-27 | Kelvin W. Gee | Compositions and methods for alleviating stress, anxiety and seizure activity |
US5232917A (en) * | 1987-08-25 | 1993-08-03 | University Of Southern California | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series |
US5120723A (en) * | 1987-08-25 | 1992-06-09 | University Of Southern California | Method, compositions, and compounds for modulating brain excitability |
US5512429A (en) | 1989-09-19 | 1996-04-30 | British Technology Group Limited | Assay for enzyme activity |
GB9105707D0 (en) | 1991-03-18 | 1991-05-01 | Wilton David C | Assay |
US5114388A (en) * | 1991-07-26 | 1992-05-19 | True Fitness Technology, Inc. | Stair simulator exerciser with adjustable incline |
US5212167A (en) * | 1991-09-12 | 1993-05-18 | Trustees Of Boston University | Modulation of receptor-mediated ion transport |
US5206415A (en) * | 1991-12-20 | 1993-04-27 | Washington University | Tricyclic steroid analogs |
ATE275957T1 (de) * | 1993-01-19 | 2004-10-15 | Endorech Inc | Therapeutische verwendungen und verabreichungsysteme von dehydroepiandrosteron |
US5776923A (en) * | 1993-01-19 | 1998-07-07 | Endorecherche, Inc. | Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone |
DE4311870C2 (de) | 1993-04-10 | 1998-07-30 | Altramed Holdings Ltd | Verwendung eines Anti-Östrigens zur Therapie und Prophylaxe von Demenz-Erkrankungen |
AU7569194A (en) * | 1993-08-20 | 1995-03-21 | Meyer B. Jackson | Method for regulating neuropeptide hormone secretion |
US5763431A (en) * | 1993-08-20 | 1998-06-09 | Jackson; Meyer B. | Method for regulating neuropeptide hormone secretion |
US5939545A (en) * | 1994-02-14 | 1999-08-17 | Cocensys, Inc. | Method, compositions, and compounds for allosteric modulation of the gaba receptor by members of the androstane and pregnane series |
US5633011A (en) * | 1994-08-04 | 1997-05-27 | Alza Corporation | Progesterone replacement therapy |
FR2727117A1 (fr) * | 1994-11-18 | 1996-05-24 | Geffard Michel | Utilisation de conjugues de la polylysine pour la preparation de medicaments utiles dans le traitement des maladies neurodegeneratives et des affections degeneratives a caractere autoimmun |
US5767117A (en) * | 1994-11-18 | 1998-06-16 | The General Hospital Corporation | Method for treating vascular headaches |
US5741899A (en) * | 1995-02-02 | 1998-04-21 | Cell Genesys, Inc. | Chimeric receptors comprising janus kinase for regulating cellular pro liferation |
GEP20012530B (en) * | 1995-06-06 | 2001-09-25 | Cocensys Inc | Neuroactive Steroids of the Androstane and Pregnane Series |
AU706541B2 (en) * | 1995-06-09 | 1999-06-17 | Euro-Celtique S.A. | Formulations and methods for providing prolonged local anesthesia |
US5888996A (en) * | 1995-07-26 | 1999-03-30 | Trustees Of Boston University | Inhibition of NMDA receptor activity and modulation of glutamate-mediated synaptic activity |
WO1997043989A1 (en) | 1996-05-22 | 1997-11-27 | Diversified Pharmaceuticals, Inc. | Compositions, methods and devices for the transdermal delivery of drugs |
US5763492A (en) * | 1996-10-01 | 1998-06-09 | Duguesne University Of The Holy Ghost | Methods for effecting memory enhancement mediated by non-steroidal sulfatase inhibitors |
DE69809223T2 (de) | 1997-05-02 | 2003-07-24 | Wyeth Corp | 5-alpha-pregnan-3-beta-ol-20-one 3-sulfate für di behandlung von tumoren und zns krankheiten |
US6245757B1 (en) * | 1997-10-03 | 2001-06-12 | Research Corporation Technologies, Inc. | Use of progestins to treat ischemic event |
US6174547B1 (en) * | 1999-07-14 | 2001-01-16 | Alza Corporation | Dosage form comprising liquid formulation |
US6268223B1 (en) | 1999-08-27 | 2001-07-31 | Viatech Imagin, Llc | Assay for detecting damage to the central nervous system |
US20020072509A1 (en) * | 2000-10-11 | 2002-06-13 | Stein Donald Gerald | Methods for the treatment of a traumatic central nervous system injury |
US7473687B2 (en) * | 2005-03-24 | 2009-01-06 | Emory University | Methods for the treatment of a traumatic central nervous system injury |
ES2428313T3 (es) * | 2005-03-24 | 2013-11-07 | Emory University | Métodos para el tratamiento de lesiones del sistema nervioso central mediante un protocolo de administración decreciente |
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2006
- 2006-03-24 ES ES11177154T patent/ES2428313T3/es active Active
- 2006-03-24 EP EP06739662A patent/EP1871382B1/de active Active
- 2006-03-24 PT PT08167618T patent/PT2030622E/pt unknown
- 2006-03-24 CA CA2601715A patent/CA2601715C/en not_active Expired - Fee Related
- 2006-03-24 PT PT06748657T patent/PT1868614E/pt unknown
- 2006-03-24 CA CA2602950A patent/CA2602950C/en not_active Expired - Fee Related
- 2006-03-24 AT AT06739662T patent/ATE520404T1/de not_active IP Right Cessation
- 2006-03-24 US US11/909,276 patent/US20090221544A1/en not_active Abandoned
- 2006-03-24 WO PCT/US2006/010797 patent/WO2006102596A2/en active Application Filing
- 2006-03-24 EP EP08167618A patent/EP2030622B1/de active Active
- 2006-03-24 RS RS20120433A patent/RS52471B/en unknown
- 2006-03-24 EP EP06748657A patent/EP1868614B1/de active Active
- 2006-03-24 DE DE602006020353T patent/DE602006020353D1/de active Active
- 2006-03-24 ES ES06748657T patent/ES2392454T3/es active Active
- 2006-03-24 AT AT08167618T patent/ATE499104T1/de active
- 2006-03-24 EP EP12163432A patent/EP2494976A1/de not_active Withdrawn
- 2006-03-24 AU AU2006226811A patent/AU2006226811B2/en not_active Ceased
- 2006-03-24 PL PL08167618T patent/PL2030622T3/pl unknown
- 2006-03-24 PL PL06748657T patent/PL1868614T3/pl unknown
- 2006-03-24 DK DK06748657.1T patent/DK1868614T3/da active
- 2006-03-24 JP JP2008503262A patent/JP5394059B2/ja not_active Expired - Fee Related
- 2006-03-24 JP JP2008503227A patent/JP5295755B2/ja not_active Expired - Fee Related
- 2006-03-24 AU AU2006226774A patent/AU2006226774B2/en not_active Ceased
- 2006-03-24 US US11/909,278 patent/US20090325920A1/en not_active Abandoned
- 2006-03-24 EP EP11177154.9A patent/EP2431042B1/de active Active
- 2006-03-24 DK DK08167618.1T patent/DK2030622T3/da active
- 2006-03-24 WO PCT/US2006/010984 patent/WO2006102644A2/en active Application Filing
-
2008
- 2008-06-25 HK HK08107067.5A patent/HK1112579A1/xx not_active IP Right Cessation
- 2008-06-30 HK HK08107230.7A patent/HK1112581A1/xx not_active IP Right Cessation
-
2009
- 2009-08-14 HK HK09107489.4A patent/HK1128242A1/xx not_active IP Right Cessation
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2011
- 2011-03-17 HR HR20110198T patent/HRP20110198T1/hr unknown
- 2011-05-20 CY CY20111100496T patent/CY1111478T1/el unknown
- 2011-08-17 JP JP2011178655A patent/JP2011225629A/ja not_active Withdrawn
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2012
- 2012-04-24 US US13/454,503 patent/US20120245133A1/en not_active Abandoned
- 2012-07-16 US US13/550,148 patent/US8614203B2/en active Active
- 2012-08-30 HR HRP20120688TT patent/HRP20120688T1/hr unknown
- 2012-10-25 CY CY20121101012T patent/CY1113253T1/el unknown
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2013
- 2013-07-12 JP JP2013146680A patent/JP2013234191A/ja not_active Withdrawn
- 2013-12-20 JP JP2013263682A patent/JP5496407B2/ja not_active Expired - Fee Related
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