HK1123551A1 - Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl) amino benzonitrile - Google Patents

Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl) amino benzonitrile

Info

Publication number
HK1123551A1
HK1123551A1 HK09100991.0A HK09100991A HK1123551A1 HK 1123551 A1 HK1123551 A1 HK 1123551A1 HK 09100991 A HK09100991 A HK 09100991A HK 1123551 A1 HK1123551 A1 HK 1123551A1
Authority
HK
Hong Kong
Prior art keywords
pyrimidinyl
dihydro
oxo
preparing
amino benzonitrile
Prior art date
Application number
HK09100991.0A
Other languages
English (en)
Inventor
Didier Philippe Robert Schils
Alfred Elisabeth Stappers
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of HK1123551A1 publication Critical patent/HK1123551A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
HK09100991.0A 2005-05-26 2009-02-04 Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl) amino benzonitrile HK1123551A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05104531 2005-05-26
US68599305P 2005-05-31 2005-05-31
PCT/EP2006/062606 WO2006125809A1 (en) 2005-05-26 2006-05-24 Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl)amino benzonitrile

Publications (1)

Publication Number Publication Date
HK1123551A1 true HK1123551A1 (en) 2009-06-19

Family

ID=35822492

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09100991.0A HK1123551A1 (en) 2005-05-26 2009-02-04 Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl) amino benzonitrile

Country Status (20)

Country Link
US (2) US8101752B2 (xx)
EP (1) EP1888537B1 (xx)
JP (2) JP5148483B2 (xx)
CN (1) CN101248051B (xx)
AU (1) AU2006251163C1 (xx)
BR (1) BRPI0611038B8 (xx)
CA (1) CA2609716C (xx)
DK (1) DK1888537T3 (xx)
ES (1) ES2437202T3 (xx)
HK (1) HK1123551A1 (xx)
HR (1) HRP20131133T1 (xx)
IN (1) IN2014DN04588A (xx)
ME (1) ME01612B (xx)
MX (1) MX2007014881A (xx)
PL (1) PL1888537T3 (xx)
PT (1) PT1888537E (xx)
RS (1) RS53062B (xx)
RU (1) RU2458056C2 (xx)
SI (1) SI1888537T1 (xx)
WO (1) WO2006125809A1 (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007014881A (es) * 2005-05-26 2008-02-15 Tibotec Pharm Ltd Procedimiento para preparar 4-(1,6-dihidro-6-oxo-2-pirimidinil) amino benzonitrilo.
WO2012125993A1 (en) 2011-03-17 2012-09-20 Teva Pharmaceutical Industries Ltd. Solid state forms of rilpivirine base, and rilipivirine salts
US10112972B2 (en) 2012-03-13 2018-10-30 Octapharma Ag Process for production of fibrinogen and fibrinogen produced thereby
CN103058936B (zh) * 2013-01-23 2016-01-06 宁波九胜创新医药科技有限公司 4-[(4-氯-2-嘧啶基)氨基]苯腈的制备方法
CN103193719B (zh) * 2013-04-08 2015-07-22 宁波九胜创新医药科技有限公司 一种4-[(4-羟基-2-嘧啶基)氨基]苯腈的制备方法
CN114933567B (zh) * 2022-04-29 2023-07-11 武汉工程大学 一种2-甲硫基-4-嘧啶酮的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63502B1 (en) 1989-04-21 1995-05-03 Zeneca Ltd Aminopyrimidine derivatives useful for treating cardiovascular disorders
DE3923979A1 (de) 1989-07-20 1991-01-24 Merck Patent Gmbh Verfahren zur herstellung von aromatischen nitrilen
RU2037483C1 (ru) * 1989-07-20 1995-06-19 Мерк Патент Гмбх Способ получения замещенных ароматических нитрилов
WO1999050250A1 (en) * 1998-03-27 1999-10-07 Janssen Pharmaceutica N.V. Hiv inhibiting pyrimidine derivatives
OA11674A (en) * 1998-11-10 2005-01-12 Janssen Pharmaceutica Nv HIV Replication inhibiting pyrimidines.
EA005423B1 (ru) * 1999-09-24 2005-02-24 Янссен Фармацевтика Н.В. Противовирусные композиции
DK1282607T3 (en) * 2000-05-08 2016-02-01 Janssen Pharmaceutica Nv Prodrugs of HIV replication inhibiting pyrimidines
JO3429B1 (ar) * 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
EP1448556A1 (en) 2001-11-01 2004-08-25 Janssen Pharmaceutica N.V. Heteroaryl amines as glycogen synthase kinase 3beta inhibitors (gsk3 inhibitors)
CN101481356B (zh) * 2002-08-09 2012-07-11 詹森药业有限公司 制备4-[[4-[[4-(2-氰基乙烯基)-2,6-二甲基苯基]氨基]-2-嘧啶基]氨基]苄腈的方法
US7432378B2 (en) * 2003-09-30 2008-10-07 Janssen Pharmaceutica, N.V. Benzoimidazole compounds
MX2007014881A (es) * 2005-05-26 2008-02-15 Tibotec Pharm Ltd Procedimiento para preparar 4-(1,6-dihidro-6-oxo-2-pirimidinil) amino benzonitrilo.

Also Published As

Publication number Publication date
CA2609716A1 (en) 2006-11-30
ME01612B (me) 2014-09-20
RU2007148968A (ru) 2009-07-10
CA2609716C (en) 2014-10-14
AU2006251163C1 (en) 2012-07-12
CN101248051A (zh) 2008-08-20
MX2007014881A (es) 2008-02-15
ES2437202T3 (es) 2014-01-09
JP5148483B2 (ja) 2013-02-20
PL1888537T3 (pl) 2014-02-28
AU2006251163A1 (en) 2006-11-30
EP1888537B1 (en) 2013-09-11
BRPI0611038B1 (pt) 2022-02-08
WO2006125809A1 (en) 2006-11-30
AU2006251163B2 (en) 2012-03-08
JP5580385B2 (ja) 2014-08-27
HRP20131133T1 (hr) 2014-01-03
BRPI0611038B8 (pt) 2022-10-25
IN2014DN04588A (xx) 2015-07-10
RS53062B (en) 2014-04-30
SI1888537T1 (sl) 2014-01-31
PT1888537E (pt) 2013-11-26
BRPI0611038A2 (pt) 2010-08-10
JP2008545680A (ja) 2008-12-18
US8101752B2 (en) 2012-01-24
US20080171878A1 (en) 2008-07-17
US8618291B2 (en) 2013-12-31
EP1888537A1 (en) 2008-02-20
RU2458056C2 (ru) 2012-08-10
CN101248051B (zh) 2013-07-17
US20120083606A1 (en) 2012-04-05
JP2013040194A (ja) 2013-02-28
DK1888537T3 (da) 2013-12-09

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