HK1121491A1 - Method for nucleic acid replication and novel artificial base pairs - Google Patents

Method for nucleic acid replication and novel artificial base pairs

Info

Publication number
HK1121491A1
HK1121491A1 HK09101422.7A HK09101422A HK1121491A1 HK 1121491 A1 HK1121491 A1 HK 1121491A1 HK 09101422 A HK09101422 A HK 09101422A HK 1121491 A1 HK1121491 A1 HK 1121491A1
Authority
HK
Hong Kong
Prior art keywords
nucleic acid
base pairs
novel artificial
acid replication
artificial base
Prior art date
Application number
HK09101422.7A
Other languages
English (en)
Inventor
Ichiro Hirao
Shigeyuki Yokoyama
Original Assignee
Riken
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riken filed Critical Riken
Publication of HK1121491A1 publication Critical patent/HK1121491A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/34Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044Pyrrole radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK09101422.7A 2005-12-09 2009-02-16 Method for nucleic acid replication and novel artificial base pairs HK1121491A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2005356883 2005-12-09
JP2006189806 2006-07-10
PCT/JP2006/324484 WO2007066737A1 (ja) 2005-12-09 2006-12-07 核酸の複製の方法及び新規人工塩基対

Publications (1)

Publication Number Publication Date
HK1121491A1 true HK1121491A1 (en) 2009-04-24

Family

ID=38122882

Family Applications (1)

Application Number Title Priority Date Filing Date
HK09101422.7A HK1121491A1 (en) 2005-12-09 2009-02-16 Method for nucleic acid replication and novel artificial base pairs

Country Status (9)

Country Link
US (1) US8030478B2 (ja)
EP (1) EP1970445B1 (ja)
JP (1) JP5146957B2 (ja)
KR (1) KR101404374B1 (ja)
CN (1) CN101365791B (ja)
AU (1) AU2006323745B2 (ja)
CA (1) CA2642657A1 (ja)
HK (1) HK1121491A1 (ja)
WO (1) WO2007066737A1 (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5649018B2 (ja) 2005-08-04 2015-01-07 タグシクス・バイオ株式会社 新規人工塩基対及びその利用
WO2009099073A1 (ja) * 2008-02-07 2009-08-13 The University Of Tokyo 非天然塩基を含む改変tRNA及びその用途
AU2009232716B2 (en) * 2008-03-31 2015-02-05 Tagcyx Biotechnologies Novel DNA capable of being amplified by PCR with high selectivity and high efficiency
US8895712B2 (en) 2009-10-06 2014-11-25 Riken Artificial base pair capable of forming specific base pair
JP6307675B2 (ja) 2011-11-18 2018-04-11 タグシクス・バイオ株式会社 標的タンパク質に結合する核酸断片
JP2016531122A (ja) 2013-08-08 2016-10-06 ザ スクリップス リサーチ インスティテュートThe Scripps Research Institute 非天然ヌクレオチドの取り込みによるインビトロの核酸の部位特異的な酵素標識のための方法
EP3129493B1 (en) 2014-04-09 2021-07-07 The Scripps Research Institute Import of unnatural or modified nucleoside triphosphates into cells via nucleic acid triphosphate transporters
US10760083B2 (en) * 2015-10-30 2020-09-01 Tagcyx Biotechnologies Inc. DNA aptamer that binds to vWF
WO2017106767A1 (en) 2015-12-18 2017-06-22 The Scripps Research Institute Production of unnatural nucleotides using a crispr/cas9 system
CN109661232B (zh) * 2016-05-23 2023-03-03 纽约哥伦比亚大学董事会 核苷酸衍生物及其使用方法
EP4163293A1 (en) 2016-06-24 2023-04-12 The Scripps Research Institute Novel nucleoside triphosphate transporter and uses thereof
AU2018300069A1 (en) 2017-07-11 2020-02-27 Synthorx, Inc. Incorporation of unnatural nucleotides and methods thereof
WO2019028425A1 (en) 2017-08-03 2019-02-07 Synthorx, Inc. CONJUGATES OF CYTOKINE FOR THE TREATMENT OF AUTOIMMUNE DISEASES
MX2020008772A (es) 2018-02-26 2020-10-01 Synthorx Inc Conjugados de il-15, y sus usos.
US20190292596A1 (en) * 2018-03-21 2019-09-26 Roche Molecular Systems, Inc. Modified nucleoside phosphates with high thermal stability
CN113518830A (zh) * 2019-01-31 2021-10-19 新加坡科技研究局 对具有非天然碱基对的核酸进行测序的方法
MX2021009259A (es) 2019-02-06 2021-08-24 Synthorx Inc Conjugados de il-2 y metodos de uso del mismo.
JP2022538784A (ja) 2019-06-14 2022-09-06 ザ スクリプス リサーチ インスティテュート 半合成生物における複製、転写および翻訳のための試薬ならびに方法
CN111214484B (zh) * 2020-01-21 2021-04-06 北京工商大学 一种共轭聚合物和聚集诱导发光小分子共掺的纳米粒子及其制备方法和应用
KR20230123501A (ko) * 2020-12-18 2023-08-23 탁시스 바이오 가부시키가이샤 Dna 앱타머의 스크리닝에 사용 가능한 신규 인공 염기를갖는 디옥시리보뉴클레오시드, 디옥시리보뉴클레오티드, 및 이를 함유하는 핵산
KR20220125170A (ko) 2021-03-04 2022-09-14 전북대학교산학협력단 인공 염기 화합물, 이를 포함하는 핵산 및 이의 용도, 및 핵산 제조 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1152009B2 (en) * 1999-02-12 2017-09-06 Daiichi Sankyo Company, Limited Novel nucleosides and oligonucleotide analogues
JP3893057B2 (ja) 1999-07-15 2007-03-14 独立行政法人科学技術振興機構 新規な核酸塩基対
WO2004007713A1 (ja) 2002-07-17 2004-01-22 Riken 新規な非天然型塩基を有するヌクレオシド又はヌクレオチド及びその利用
JP4956802B2 (ja) 2003-09-10 2012-06-20 独立行政法人理化学研究所 非天然型塩基を有するヌクレオシド又はヌクレオチド及びその利用
JP5649018B2 (ja) 2005-08-04 2015-01-07 タグシクス・バイオ株式会社 新規人工塩基対及びその利用

Also Published As

Publication number Publication date
JPWO2007066737A1 (ja) 2009-05-21
AU2006323745A1 (en) 2007-06-14
CN101365791A (zh) 2009-02-11
EP1970445B1 (en) 2012-09-26
JP5146957B2 (ja) 2013-02-20
EP1970445A4 (en) 2009-07-29
US8030478B2 (en) 2011-10-04
KR101404374B1 (ko) 2014-06-09
CN101365791B (zh) 2012-07-25
US20100036111A1 (en) 2010-02-11
WO2007066737A1 (ja) 2007-06-14
KR20080093986A (ko) 2008-10-22
EP1970445A1 (en) 2008-09-17
AU2006323745B2 (en) 2012-11-22
CA2642657A1 (en) 2007-06-14

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