HK1116796A1 - Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands - Google Patents

Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands

Info

Publication number
HK1116796A1
HK1116796A1 HK08111412.9A HK08111412A HK1116796A1 HK 1116796 A1 HK1116796 A1 HK 1116796A1 HK 08111412 A HK08111412 A HK 08111412A HK 1116796 A1 HK1116796 A1 HK 1116796A1
Authority
HK
Hong Kong
Prior art keywords
sulphonamide derivatives
ligands
functional
aminoaryl
aminoaryl sulphonamide
Prior art date
Application number
HK08111412.9A
Other languages
English (en)
Inventor
Venkata Satya Nirogi Ramakrishna
Vikas Shreekrishna Shirsath
Rama Sastri Kambhampati
Santosh Vishwakarma
Nagaraj Vishwottam Kandikere
Srinivasulu Kota
Venkateswarlu Jasti
Original Assignee
Suven Life Sciences Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suven Life Sciences Ltd filed Critical Suven Life Sciences Ltd
Publication of HK1116796A1 publication Critical patent/HK1116796A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Nutrition Science (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Semiconductor Integrated Circuits (AREA)
  • Insulated Gate Type Field-Effect Transistor (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
HK08111412.9A 2005-08-12 2008-10-15 Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands HK1116796A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1127CH2005 2005-08-12
PCT/IN2005/000345 WO2007020652A1 (fr) 2005-08-12 2005-10-26 Dérivés de sulphonamide aminoaryles comme ligands fonctionnels 5-ht6.

Publications (1)

Publication Number Publication Date
HK1116796A1 true HK1116796A1 (en) 2009-01-02

Family

ID=36130030

Family Applications (1)

Application Number Title Priority Date Filing Date
HK08111412.9A HK1116796A1 (en) 2005-08-12 2008-10-15 Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands

Country Status (23)

Country Link
US (1) US7998981B2 (fr)
EP (1) EP1919896B1 (fr)
JP (1) JP5091138B2 (fr)
KR (1) KR101016972B1 (fr)
CN (1) CN101258144B (fr)
AT (1) ATE452885T1 (fr)
AU (1) AU2005335620B2 (fr)
BR (1) BRPI0520579B8 (fr)
CA (1) CA2618636C (fr)
CY (1) CY1110276T1 (fr)
DE (1) DE602005018554D1 (fr)
DK (1) DK1919896T3 (fr)
EA (1) EA013875B1 (fr)
ES (1) ES2337167T3 (fr)
HK (1) HK1116796A1 (fr)
MX (1) MX2008002018A (fr)
NO (1) NO340511B1 (fr)
NZ (1) NZ566495A (fr)
PL (1) PL1919896T3 (fr)
PT (1) PT1919896E (fr)
SI (1) SI1919896T1 (fr)
WO (1) WO2007020652A1 (fr)
ZA (1) ZA200801276B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007343063B2 (en) 2007-01-08 2011-02-17 Suven Life Sciences Limited 5-(Heterocyclyl)alkyl-N-(arylsulfonyl)indole compounds and their use as 5-HT6 ligands
DK2155674T3 (da) 2007-05-03 2011-09-26 Suven Life Sciences Ltd Aminoalkoxy-aryl-sulfonamidforbindelser og anvendelse heraf som 5-HT6-ligander
WO2009053997A1 (fr) * 2007-10-26 2009-04-30 Suven Life Sciences Limited Composés d'aminoarylsulfonamide et leur utilisation comme ligands de 5-ht6
US8318725B2 (en) 2008-09-17 2012-11-27 Suven Life Sciences Limited Aryl indolyl sulfonamide compounds and their use as 5-HT6 ligands
KR101463190B1 (ko) * 2010-01-05 2014-11-18 수벤 라이프 사이언시스 리미티드 ５­ｈｔ６ 수용체 리간드인 술폰 화합물
CN102153884B (zh) * 2011-02-16 2013-06-19 连云港清泰化工有限公司 一种墨水型染料及其制备方法与用途
JP6454346B2 (ja) 2013-12-20 2019-01-16 サンシャイン・レイク・ファーマ・カンパニー・リミテッドＳｕｎｓｈｉｎｅ Ｌａｋｅ Ｐｈａｒｍａ Ｃｏ．，Ｌｔｄ． 芳香族複素環式化合物及び医薬におけるその応用
EP3166924B1 (fr) 2014-07-08 2019-02-20 Sunshine Lake Pharma Co., Ltd. Dérivés hétérocycliques aromatiques et leurs applications pharmaceutiques

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2143992T3 (es) * 1991-11-25 2000-06-01 Pfizer Derivados de 5-(hetero- o carbociclilamino)-indol, su preparacion y uso como 5-ht1 agonistas.
DZ2376A1 (fr) 1996-12-19 2002-12-28 Smithkline Beecham Plc Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant.
BR9810991A (pt) 1997-07-11 2000-08-08 Smithkline Beecham Plc Novos compostos
GB9801392D0 (en) 1998-01-22 1998-03-18 Smithkline Beecham Plc Novel compounds
GB9803411D0 (en) 1998-02-18 1998-04-15 Smithkline Beecham Plc Novel compounds
GB9926302D0 (en) 1999-11-05 2000-01-12 Smithkline Beecham Plc Novel compounds
DK1355900T3 (da) * 2000-12-22 2006-09-11 Wyeth Corp Heterocyclylalkylindol- eller -azaindolforbindelser som 5-hydroxytryptamin-6-ligander
CA2438099A1 (fr) 2001-02-08 2002-12-12 Memory Pharmaceuticals Corporation Trifluoromethylpurines en tant qu'inhibiteurs de la phosphodiesterase 4
US6565829B2 (en) * 2001-08-03 2003-05-20 Pharmacia & Upjohn Company 5-arylsulfonyl indoles useful for treating disease
WO2003065046A2 (fr) 2002-02-01 2003-08-07 Bayer Healthcare Ag Moyens diagnostiques et therapeutiques pour la prevention et le traitement de maladies associees au nouveau recepteur 5-ht6 humain
US20070270432A1 (en) 2002-02-05 2007-11-22 James Hagan Novel Method
WO2003072548A1 (fr) * 2002-02-22 2003-09-04 Pharmacia & Upjohn Company Derives de pyridyl sulfone utilises comme antagonistes du recepteur 5-ht
KR100657056B1 (ko) * 2002-06-05 2006-12-13 에프. 호프만-라 로슈 아게 중추 신경계 장애의 치료를 위한 5-ｈｔ6-수용체조절제로서 1-설폰일-4-아미노알콕시 인돌 유도체
WO2004035047A1 (fr) * 2002-10-18 2004-04-29 F. Hoffmann-La Roche Ag Indoles 4-piperazinyle benzenesulfonyle presentant une affinite pour le recepteur 5-ht6
WO2004048331A1 (fr) 2002-11-28 2004-06-10 Suven Life Sciences Limited N-arylalkyl-3-aminoalcoxyindoles et leur utilisation en tant que ligands des recepteurs 5-ht
KR100776118B1 (ko) 2002-11-28 2007-11-15 수벤 라이프 사이언시스 리미티드 엔-아릴술포닐-3-아미노알콕시인돌
KR100818508B1 (ko) 2002-11-28 2008-03-31 수벤 라이프 사이언시스 리미티드 세로토닌 수용체 친화력을 가지는 엔-아릴술포닐-3-치환인돌, 그 제조방법 및 그를 포함하는 약제학적 조성물
NZ540841A (en) 2002-12-18 2008-08-29 Suven Life Sciences Ltd Tetracyclic 3-substituted indoles having serotonin receptor affinity
EP1663193B1 (fr) * 2003-09-12 2012-04-04 Merck Serono SA Derives de sulfonamide pour le traitement du diabete

Also Published As

Publication number Publication date
NO340511B1 (no) 2017-05-02
MX2008002018A (es) 2008-03-27
AU2005335620A1 (en) 2007-02-22
PL1919896T3 (pl) 2010-05-31
DK1919896T3 (da) 2010-04-19
KR101016972B1 (ko) 2011-02-25
CA2618636A1 (fr) 2007-02-22
WO2007020652A1 (fr) 2007-02-22
ATE452885T1 (de) 2010-01-15
CN101258144A (zh) 2008-09-03
EA013875B1 (ru) 2010-08-30
KR20080039984A (ko) 2008-05-07
US7998981B2 (en) 2011-08-16
ES2337167T3 (es) 2010-04-21
BRPI0520579B8 (pt) 2021-05-25
AU2005335620B2 (en) 2009-12-10
EA200800573A1 (ru) 2008-08-29
PT1919896E (pt) 2010-02-26
CN101258144B (zh) 2012-05-30
CA2618636C (fr) 2011-01-18
JP5091138B2 (ja) 2012-12-05
SI1919896T1 (sl) 2010-04-30
NZ566495A (en) 2010-06-25
CY1110276T1 (el) 2015-01-14
EP1919896B1 (fr) 2009-12-23
JP2009504633A (ja) 2009-02-05
US20100168168A1 (en) 2010-07-01
BRPI0520579B1 (pt) 2019-08-06
ZA200801276B (en) 2009-02-25
NO20080705L (no) 2008-05-06
BRPI0520579A2 (pt) 2009-11-10
EP1919896A1 (fr) 2008-05-14
DE602005018554D1 (de) 2010-02-04

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20201027