HK1106136A1 - Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases - Google Patents

Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases

Info

Publication number
HK1106136A1
HK1106136A1 HK07111416.6A HK07111416A HK1106136A1 HK 1106136 A1 HK1106136 A1 HK 1106136A1 HK 07111416 A HK07111416 A HK 07111416A HK 1106136 A1 HK1106136 A1 HK 1106136A1
Authority
HK
Hong Kong
Prior art keywords
treatment
drug resistant
quinoline derivatives
substituted quinoline
mycobacterial diseases
Prior art date
Application number
HK07111416.6A
Other languages
English (en)
Inventor
Koenraad Jozef Lodewijk Marcel Andries
Jozef Frans Elisabetha Van Gestel
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34929150&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1106136(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of HK1106136A1 publication Critical patent/HK1106136A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
HK07111416.6A 2004-05-28 2007-10-23 Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases HK1106136A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04102402 2004-05-28
PCT/EP2005/052371 WO2005117875A1 (en) 2004-05-28 2005-05-24 Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases

Publications (1)

Publication Number Publication Date
HK1106136A1 true HK1106136A1 (en) 2008-03-07

Family

ID=34929150

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07111416.6A HK1106136A1 (en) 2004-05-28 2007-10-23 Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases

Country Status (35)

Country Link
US (2) US20070249667A1 (ja)
EP (1) EP1753427B1 (ja)
JP (2) JP5081617B2 (ja)
KR (2) KR101371653B1 (ja)
CN (2) CN102908347A (ja)
AP (1) AP2037A (ja)
AR (1) AR049127A1 (ja)
AT (1) ATE390925T1 (ja)
AU (1) AU2005249231B2 (ja)
BR (1) BRPI0510414B1 (ja)
CA (1) CA2566544C (ja)
CL (1) CL2009001980A1 (ja)
CY (1) CY1110388T1 (ja)
DE (1) DE602005005810T2 (ja)
DK (1) DK1753427T3 (ja)
EA (1) EA010651B1 (ja)
ES (1) ES2306146T3 (ja)
HK (1) HK1106136A1 (ja)
HR (1) HRP20080307T3 (ja)
IL (1) IL179630A (ja)
JO (1) JO2524B1 (ja)
ME (1) ME01105B (ja)
MX (1) MXPA06013888A (ja)
MY (1) MY140611A (ja)
NO (1) NO338624B1 (ja)
NZ (1) NZ550840A (ja)
PA (1) PA8635201A1 (ja)
PL (1) PL1753427T3 (ja)
PT (1) PT1753427E (ja)
RS (1) RS50585B (ja)
SI (1) SI1753427T1 (ja)
TW (1) TWI363625B (ja)
UA (1) UA90267C2 (ja)
WO (1) WO2005117875A1 (ja)
ZA (1) ZA200609899B (ja)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5081617B2 (ja) * 2004-05-28 2012-11-28 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 薬剤耐性マイコバクテリア性疾患の処置のための置換キノリン誘導体の使用
EA009779B1 (ru) * 2004-12-24 2008-04-28 Янссен Фармацевтика Н.В. Лечение латентного туберкулёза
CA2528849C (en) * 2005-06-08 2014-01-14 Janssen Pharmaceutica N.V. Quinoline derivatives as antibacterial agents
JP5349730B2 (ja) * 2005-06-09 2013-11-20 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 抗バクテリア剤としてのキノリン誘導体
JO3270B1 (ar) * 2005-06-28 2018-09-16 Janssen Pharmaceutica Nv مشتقات كوينولين بصفة عوامل مضادة للبكتيريا
JO2752B1 (en) * 2005-06-28 2014-03-15 شركة جانسين فارماسوتيكا ان. في Quinoline derivatives acting as antibacterial agents
BRPI0613999B8 (pt) * 2005-06-28 2021-05-25 Janssen Pharmaceutica Nv uso de um composto derivado de quinolina, o referido composto, sua combinação, composição farmacêutica, uso da referida combinação, e produto
EP1917245A1 (de) 2005-08-21 2008-05-07 Abbott GmbH & Co. KG Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren
UA97813C2 (uk) * 2006-12-05 2012-03-26 Янссен Фармацевтика Н.В. Фумаратна сіль (альфа s, бета r)-6-бром-альфа-[2-(диметиламіно)етил]-2-метоксі-альфа-1-нафталеніл-бета-феніл-3-хінолінетанолу
JO2970B1 (en) * 2006-12-06 2016-03-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2683B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2725B1 (en) * 2006-12-06 2013-09-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2684B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
JO2685B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
JO3271B1 (ar) * 2006-12-06 2018-09-16 Janssen Pharmaceutica Nv مشتقات الكوينولين المضادة للجراثيم
MD4009C2 (ro) * 2008-07-15 2010-08-31 Институт Химии Академии Наук Молдовы Utilizarea 1-metil-4-(N-metilaminobutil-4)-β-carbolinei în calitate de remediu antituberculos
RU2404971C2 (ru) * 2008-12-02 2010-11-27 ЗАО "Фарм-Синтез" Новые производные хинолина, способ их получения, их применение для лечения микобактериальных инфекций, фармацевтическая композиция на их основе
EP2475365A1 (en) * 2009-09-11 2012-07-18 Vertex Pharmaceuticals Incorporated Compositions of n-benzyl-3-(4-chlorophenyl)-2-[methyl-[2-oxo-2-(3,4,5-trimethoxyphenyl) acetyl]amino]-n-[3-(4-pyri(dyl)-1-[2-[4-pyridyl)ethyl]propyl]propanamide and uses thereof
CN102249935B (zh) * 2010-05-17 2015-05-20 中国人民解放军军事医学科学院毒物药物研究所 芳香2-丁醇类化合物及其医药用途
ES2607879T3 (es) 2012-04-27 2017-04-04 Janssen Pharmaceutica N.V. Derivados de quinolina antibacterianos
EP2841425B1 (en) 2012-04-27 2016-03-23 Janssen Pharmaceutica, N.V. Antibacterial quinoline derivatives
US9878982B2 (en) * 2014-07-14 2018-01-30 Cisen Pharmaceutical Co., Ltd. Pyridine derivatives and anti-mycobacterial use thereof
CN105330595B (zh) * 2014-07-14 2019-12-10 上海嘉坦医药科技有限公司 吡啶衍生物及其作为抗分支杆菌的应用
PT3250182T (pt) 2015-01-27 2023-07-07 Janssen Pharmaceutica Nv Composições dispersíveis
CN106279017A (zh) * 2015-05-21 2017-01-04 重庆圣华曦药业股份有限公司 贝达喹啉晶型、组合物及其制备方法
RU2018111482A (ru) * 2015-10-20 2019-11-21 Чжэцзян Хисунь Фармасьютикал Ко., Лтд. Кристаллические формы бедаквилин фумарата и способы их получения
CN108473428B (zh) * 2016-01-13 2021-07-23 上海嘉坦医药科技有限公司 一种吡啶衍生物类化合物的制备方法及其中间体和晶型
KR102355154B1 (ko) 2016-03-07 2022-01-26 더 글로벌 얼라이언스 포 티비 드러그 디벨롭먼트, 잉크. 항박테리아 화합물 및 그의 용도
CN107243008B (zh) * 2017-04-13 2021-03-30 中国科学院广州生物医药与健康研究院 吡唑并[1,5-a]吡啶类化合物的新应用及一种治疗脓肿分枝杆菌感染的组合物
US11407742B2 (en) * 2017-09-01 2022-08-09 The Kitasato Institute Compound having therapeutic activity against mycobacterium avium complex infection, and method for producing same
WO2020047596A1 (en) * 2018-09-04 2020-03-12 Monash University Antibacterial compounds and methods of use
CN113271930A (zh) 2019-01-09 2021-08-17 詹森药业有限公司 治疗非结核分枝杆菌疾病的组合
CN110804016B (zh) * 2019-12-05 2022-11-04 福建省微生物研究所 抗结核分枝杆菌的二芳基喹啉衍生物
TW202233168A (zh) 2020-11-12 2022-09-01 比利時商健生藥品公司 治療非結核分枝桿菌疾病的藥物組分之組合
CN117050006A (zh) * 2022-05-13 2023-11-14 广州嘉越医药科技有限公司 一种吡啶衍生物、中间体、制备方法和应用
WO2023227123A1 (zh) * 2022-05-27 2023-11-30 广州嘉越医药科技有限公司 吡啶衍生物的用途
WO2023232838A1 (en) 2022-05-31 2023-12-07 Janssen Pharmaceutica Nv Bedaquiline for use in the treatment of leprosy

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399558A (en) * 1993-11-24 1995-03-21 Pathogenesis Corporation Isoflavonoid antibacterial compounds, compositions and use
EP0936866A4 (en) * 1996-10-28 2001-04-11 Dept Of The Army Us Government COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING ANTIBIOTIC RESIST INFECTIONS
US6103905A (en) * 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
SI2301544T1 (sl) * 2002-07-25 2013-01-31 Janssen Pharmaceutica, N.V. Derivati kinolina kot vmesne spojine za mikobakterijske inhibitorje
JP5081617B2 (ja) * 2004-05-28 2012-11-28 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ 薬剤耐性マイコバクテリア性疾患の処置のための置換キノリン誘導体の使用
CA2528849C (en) * 2005-06-08 2014-01-14 Janssen Pharmaceutica N.V. Quinoline derivatives as antibacterial agents

Also Published As

Publication number Publication date
EA010651B1 (ru) 2008-10-30
EP1753427A1 (en) 2007-02-21
CA2566544A1 (en) 2005-12-15
RS50585B (sr) 2010-05-07
ME01105B (me) 2013-03-20
AU2005249231B2 (en) 2010-11-11
DK1753427T3 (da) 2008-07-21
KR20070017393A (ko) 2007-02-09
IL179630A (en) 2011-05-31
MXPA06013888A (es) 2007-01-26
JP5675718B2 (ja) 2015-02-25
DE602005005810D1 (de) 2008-05-15
EP1753427B1 (en) 2008-04-02
CL2009001980A1 (es) 2010-04-16
AP2037A (en) 2009-10-09
BRPI0510414B1 (pt) 2022-04-05
ES2306146T3 (es) 2008-11-01
SI1753427T1 (sl) 2008-10-31
AU2005249231A1 (en) 2005-12-15
CN102908347A (zh) 2013-02-06
AR049127A1 (es) 2006-06-28
PA8635201A1 (es) 2006-05-16
JO2524B1 (en) 2010-03-17
NO338624B1 (no) 2016-09-19
NZ550840A (en) 2010-01-29
KR20130024969A (ko) 2013-03-08
BRPI0510414A (pt) 2007-10-23
CA2566544C (en) 2012-04-17
ATE390925T1 (de) 2008-04-15
CN1976704B (zh) 2012-12-05
PT1753427E (pt) 2008-07-04
US20100168133A1 (en) 2010-07-01
UA90267C2 (ru) 2010-04-26
HRP20080307T3 (en) 2008-07-31
ZA200609899B (en) 2009-01-28
JP2008500992A (ja) 2008-01-17
KR101371653B1 (ko) 2014-03-07
PL1753427T3 (pl) 2008-09-30
WO2005117875A1 (en) 2005-12-15
TW200608974A (en) 2006-03-16
CN1976704A (zh) 2007-06-06
MY140611A (en) 2009-12-31
NO20066041L (no) 2007-02-27
AP2006003828A0 (en) 2006-12-31
JP2012229239A (ja) 2012-11-22
EA200602260A1 (ru) 2007-04-27
TWI363625B (en) 2012-05-11
CY1110388T1 (el) 2015-04-29
JP5081617B2 (ja) 2012-11-28
US20070249667A1 (en) 2007-10-25
IL179630A0 (en) 2007-07-04
DE602005005810T2 (de) 2009-04-09

Similar Documents

Publication Publication Date Title
AP2037A (en) Use of substituted quinoline derivatives for the treatment of drug resistant mycobacterial diseases
HUS1500034I1 (hu) Indolidon-származékok fibrózisos betegségek kezelésére vagy megelõzésére
HK1113797A1 (en) Quinoline derivative for the treatment of retinal diseases
HK1186125A1 (en) Quinoline derivatives for the treatment of latent tuberculosis
GB0312832D0 (en) 2-amino-pyridine derivatives useful for the treatment of diseases
HK1096083A1 (en) Sulfonamide derivatives for the treatment of diseases
AP2006003669A0 (en) Sulfonamide derivatives for the treatment of diseases
IL184124A0 (en) Medicaments for the treatment or prevention of fibrotic diseases
ZA200705160B (en) Quinoline derivatives for the treatment of latent tuberculosis
GB0425054D0 (en) Formamide derivatives for the treatment of diseases
GB0408297D0 (en) Indole derivatives for the treatment of diseases
GB0312842D0 (en) 2-amino-pyridine derivatives useful for the treatment of diseases
GB0312840D0 (en) 2-amino-pyridine derivatives useful for the treatment of diseases
GB0406387D0 (en) Sulfonamide derivatives for the treatment of diseases
GB0406388D0 (en) Sulfonamide derivatives for the treatment of diseases
IL176564A0 (en) Sulfonamide derivatives for the treatment of diseases