HK1105997A1 - Mature dendritic cell compositions and methods for culturing same - Google Patents
Mature dendritic cell compositions and methods for culturing sameInfo
- Publication number
- HK1105997A1 HK1105997A1 HK07113385.9A HK07113385A HK1105997A1 HK 1105997 A1 HK1105997 A1 HK 1105997A1 HK 07113385 A HK07113385 A HK 07113385A HK 1105997 A1 HK1105997 A1 HK 1105997A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- dendritic cells
- agonist
- signaling
- methods
- receptor
- Prior art date
Links
- 210000004443 dendritic cell Anatomy 0.000 title abstract 9
- 238000000034 method Methods 0.000 title abstract 5
- 238000012258 culturing Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000011664 signaling Effects 0.000 abstract 3
- 108010029697 CD40 Ligand Proteins 0.000 abstract 2
- 101150013553 CD40 gene Proteins 0.000 abstract 2
- 102100032937 CD40 ligand Human genes 0.000 abstract 2
- 239000000556 agonist Substances 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 230000002163 immunogen Effects 0.000 abstract 2
- 230000003308 immunostimulating effect Effects 0.000 abstract 2
- 108010085650 interferon gamma receptor Proteins 0.000 abstract 2
- 230000028327 secretion Effects 0.000 abstract 2
- 102100036301 C-C chemokine receptor type 7 Human genes 0.000 abstract 1
- 229940123189 CD40 agonist Drugs 0.000 abstract 1
- 101000716065 Homo sapiens C-C chemokine receptor type 7 Proteins 0.000 abstract 1
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 1
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 abstract 1
- 102100040245 Tumor necrosis factor receptor superfamily member 5 Human genes 0.000 abstract 1
- 230000001270 agonistic effect Effects 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 230000001052 transient effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/463—Cellular immunotherapy characterised by recombinant expression
- A61K39/4635—Cytokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/46449—Melanoma antigens
- A61K39/464491—Melan-A/MART
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/36—Lipids
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/02—Compounds of the arachidonic acid pathway, e.g. prostaglandins, leukotrienes
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/22—Colony stimulating factors (G-CSF, GM-CSF)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
-
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/52—CD40, CD40-ligand (CD154)
-
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2510/00—Genetically modified cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Communicable Diseases (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US52251204P | 2004-10-07 | 2004-10-07 | |
PCT/US2005/036304 WO2006042177A2 (en) | 2004-10-07 | 2005-10-07 | Mature dendritic cell compositions and methods for culturing same |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1105997A1 true HK1105997A1 (en) | 2008-02-29 |
Family
ID=36148973
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK07113385.9A HK1105997A1 (en) | 2004-10-07 | 2007-12-07 | Mature dendritic cell compositions and methods for culturing same |
Country Status (14)
Country | Link |
---|---|
US (4) | US8822223B2 (xx) |
EP (2) | EP2251418B1 (xx) |
JP (2) | JP5269412B2 (xx) |
KR (1) | KR101243577B1 (xx) |
CN (1) | CN101080487B (xx) |
AT (1) | ATE489455T1 (xx) |
AU (1) | AU2005294150B2 (xx) |
CA (1) | CA2577125C (xx) |
DE (1) | DE602005025005D1 (xx) |
DK (1) | DK1809737T3 (xx) |
ES (1) | ES2861199T3 (xx) |
HK (1) | HK1105997A1 (xx) |
TW (1) | TWI382843B (xx) |
WO (1) | WO2006042177A2 (xx) |
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CN101080487B (zh) | 2004-10-07 | 2012-11-14 | 阿戈斯治疗公司 | 成熟树突细胞组合物及其培养方法 |
US8513008B2 (en) | 2004-10-07 | 2013-08-20 | Argos Therapeutics, Inc. | Mature dendritic cell compositions and methods for culturing same |
CN101155914B (zh) | 2005-04-08 | 2013-03-06 | 阿戈斯治疗公司 | 树状细胞组合物和方法 |
US20090074711A1 (en) * | 2006-09-07 | 2009-03-19 | University Of Southhampton | Human therapies using chimeric agonistic anti-human cd40 antibody |
CN101522210B (zh) | 2006-09-18 | 2017-03-22 | 阿肯色大学评议会 | 增强免疫应答的组合物和方法 |
WO2008097926A2 (en) * | 2007-02-02 | 2008-08-14 | Yale University | Transient transfection with rna |
US10155038B2 (en) | 2007-02-02 | 2018-12-18 | Yale University | Cells prepared by transient transfection and methods of use thereof |
US9249423B2 (en) | 2007-02-02 | 2016-02-02 | Yale University | Method of de-differentiating and re-differentiating somatic cells using RNA |
DE102007006736B4 (de) | 2007-02-07 | 2012-01-12 | Dagmar Briechle | In-vitro Testkit zur tierversuchsfreien Bestimmung des sensibilisierenden Potentials einer Substanz |
MX2009011384A (es) | 2007-04-25 | 2010-03-18 | Immurx Inc | Combinaciones adyuvantes que comprenden un activador de nkt, un agonista de cd40 y opcionalmente un antígeno y uso de las mismas para inducir un aumento sinergístico en la inmunidad celular. |
PL2201100T3 (pl) * | 2007-09-14 | 2016-10-31 | Wzmacnianie zdolności ludzkich komórek prezentujących antygen do stymulacji komórek T i ich zastosowanie w szczepieniu | |
US9408909B2 (en) | 2007-09-14 | 2016-08-09 | Vrije Universiteit Brussel | Enhancing the T-cell stimulatory capacity of human antigen presenting cells in vitro and in vivo and its use in vaccination |
EP2201100B1 (en) * | 2007-09-14 | 2016-03-16 | Vrije Universiteit Brussel | Enhancing the t-cells stimulatory capacity of human antigen presenting cells and their use in vaccination |
NZ585776A (en) * | 2007-10-30 | 2012-07-27 | Univ Arkansas | Compositions and methods of enhancing immune responses to flagellated bacterium |
PL2214701T3 (pl) * | 2007-11-01 | 2017-01-31 | The Board Of Trustees Of The University Of Arkansas | Kompozycje i sposoby wzmacniania odpowiedzi odpornościowych na Eimeria |
EP2072617A1 (en) * | 2007-12-12 | 2009-06-24 | Trimed Biotech GmbH | Method for producing dendritic cells |
US20090263828A1 (en) * | 2008-04-16 | 2009-10-22 | Franco Lori | Novel assay for precursor T-cells having high proliferative capacity (PHPC-asay) |
CN102307989B (zh) | 2008-11-14 | 2015-04-22 | 生物载体株式会社 | 用于产生树突细胞的方法 |
US20110268757A1 (en) | 2008-12-03 | 2011-11-03 | Institut Pasteur | Use of phenol-soluble modulins for vaccine development |
US20120185969A1 (en) * | 2009-09-04 | 2012-07-19 | Syngenta Participations Ag | Stacking of translational enhancer elements to increase polypeptide expression in plants |
IN2012DN05053A (xx) * | 2009-12-04 | 2015-10-09 | Stem Cell & Regenerative Medicine Internatioinal Inc | |
UA110024C2 (uk) | 2010-01-21 | 2015-11-10 | Вакцинний вектор і спосіб посилення імунної відповіді | |
KR102007132B1 (ko) | 2010-06-09 | 2019-08-05 | 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 | 캄필로박터 감염을 감소시키기 위한 백신 및 방법 |
WO2013088114A1 (en) * | 2011-12-12 | 2013-06-20 | Cell Medica Limited | Process of expanding t cells |
NZ711019A (en) | 2013-02-14 | 2019-07-26 | Univ Arkansas | Compositions and methods of enhancing immune responses to eimeria or limiting eimeria infection |
EP2968423A4 (en) | 2013-03-15 | 2016-11-09 | Univ Arkansas | COMPOSITIONS AND METHODS FOR INCREASING IMMUNE REACTIONS AGAINST ENTERAL PATHOGENES |
JP2016081562A (ja) | 2014-10-09 | 2016-05-16 | ソニー株式会社 | 表示装置、表示装置の製造方法および電子機器 |
CA2979388A1 (en) * | 2015-03-12 | 2016-09-15 | Health Research, Inc. | Enrichment of cd16+ monocytes to improve dendritic cell vaccine quality |
CN105670994A (zh) * | 2016-02-28 | 2016-06-15 | 深圳爱生再生医学科技有限公司 | Dc诱导剂及其应用 |
CN118165113A (zh) * | 2016-04-26 | 2024-06-11 | 科济生物医药(上海)有限公司 | 一种改善免疫应答细胞功能的方法 |
BR112018072592A2 (pt) | 2016-05-03 | 2019-04-16 | The Board Of Trustees Of The University Of Arkansas | vetor de vacina de levedura que inclui polipeptídeos imunoestimulantes e antigênicos, e métodos de uso dos mesmos |
EP3706765A4 (en) | 2017-11-07 | 2021-07-14 | Coimmune, Inc. | METHODS AND USES FOR DENDRITIC CELL THERAPY |
CA3104387A1 (en) * | 2018-06-19 | 2019-12-26 | Fondazione Telethon | Production of engineered dendritic cells and uses thereof |
WO2020018413A1 (en) * | 2018-07-15 | 2020-01-23 | Enochian BioPharma, Inc. | Methods and compositions using recombinant dendritic cells for cancer therapy |
CN109797209B (zh) * | 2019-01-04 | 2021-07-16 | 中国人民解放军第二军医大学 | 一种树突状细胞和/或趋化性树突状细胞和/或其趋化状态和功能的特异性生物标志物 |
MX2021012471A (es) * | 2019-04-11 | 2022-01-04 | Univ Arkansas | Aptameros de adn especificos de cd40 como adyuvantes de vacunas. |
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AU2005294150B2 (en) | 2011-06-16 |
AU2005294150A1 (en) | 2006-04-20 |
EP1809737B1 (en) | 2010-11-24 |
CN101080487B (zh) | 2012-11-14 |
ES2861199T3 (es) | 2021-10-06 |
EP2251418A1 (en) | 2010-11-17 |
US20150072431A1 (en) | 2015-03-12 |
DE602005025005D1 (de) | 2011-01-05 |
WO2006042177A2 (en) | 2006-04-20 |
KR101243577B1 (ko) | 2013-03-20 |
TWI382843B (zh) | 2013-01-21 |
EP2251418B1 (en) | 2021-03-17 |
US20060078994A1 (en) | 2006-04-13 |
EP1809737B9 (en) | 2011-10-05 |
WO2006042177A3 (en) | 2007-02-01 |
CN101080487A (zh) | 2007-11-28 |
US11248209B2 (en) | 2022-02-15 |
US9556455B2 (en) | 2017-01-31 |
JP2008515439A (ja) | 2008-05-15 |
EP1809737A2 (en) | 2007-07-25 |
DK1809737T3 (da) | 2011-03-07 |
JP5269412B2 (ja) | 2013-08-21 |
US20080145931A1 (en) | 2008-06-19 |
ATE489455T1 (de) | 2010-12-15 |
KR20070101233A (ko) | 2007-10-16 |
TW200630491A (en) | 2006-09-01 |
JP2013121352A (ja) | 2013-06-20 |
US20170096640A1 (en) | 2017-04-06 |
CA2577125C (en) | 2016-01-12 |
US8822223B2 (en) | 2014-09-02 |
CA2577125A1 (en) | 2006-04-20 |
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