ES8606494A1 - Un metodo de producir un peptido o polipeptido sintetico. - Google Patents
Un metodo de producir un peptido o polipeptido sintetico.Info
- Publication number
- ES8606494A1 ES8606494A1 ES529232A ES529232A ES8606494A1 ES 8606494 A1 ES8606494 A1 ES 8606494A1 ES 529232 A ES529232 A ES 529232A ES 529232 A ES529232 A ES 529232A ES 8606494 A1 ES8606494 A1 ES 8606494A1
- Authority
- ES
- Spain
- Prior art keywords
- falciparum
- dna molecules
- plasmodium falciparum
- expression
- antigenicity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 241000223960 Plasmodium falciparum Species 0.000 title abstract 6
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 239000002299 complementary DNA Substances 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 3
- 102000036639 antigens Human genes 0.000 abstract 3
- 108091007433 antigens Proteins 0.000 abstract 3
- 108020004999 messenger RNA Proteins 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
- C07K14/445—Plasmodium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
- F02B—INTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
- F02B75/00—Other engines
- F02B75/02—Engines characterised by their cycles, e.g. six-stroke
- F02B2075/022—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
- F02B2075/027—Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
METODO DE PRODUCIR UN PEPTIDO O POLIPEPTIDO SINTETICO. COMPRENDE: A) CULTIVAR UNA CELULA HUESPED QUE CONTIENE: I) UNA MOLECULA DE ADN RECOMBINANTE QUE COMPRENDE UNA SECUENCIA DE NUCLEOTIDOS CAPAZ DE SER EXPRESADA COMO UN POLIPEPTIDO QUE MUESTRA LA ANTIGENICIDAD DE UN ANTIGENO DE P. FALCIPARUM (LIMITADA OPERATIVAMENTE A UNA SECUENCIA DE CONTROL DE EXPRESION); O II) UN VEHICULO O VECTOR DE CLONACION DE ADN RECOMBINANTE QUE TIENE INSERTADA EN EL UNA SECUENCIA DE NUCLEOTIDOS CAPAZ DE SER EXPRESADA COMO UN POLIPEPTIDO QUE MUESTRA LA ANTIGENICIDAD DE UN ANTIGENO DE P. FALCIPARUM (ESTANDO DICHA SECUENCIA OPERATIVAMENTE UNIDA A UNA SECUENCIA DE CONTROL DE EXPRESION); Y B) RECUPERAR DICHO PEPTIDO O POLIPEPTIDO DEL CULTIVO. SE UTILIZA EN FARMACOLOGIA EN EL TRATAMIENTO Y LA PREVENCION DE LA MALARIA.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPF784383 | 1983-01-28 | ||
AUPF978883 | 1983-06-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8606494A1 true ES8606494A1 (es) | 1986-04-16 |
ES529232A0 ES529232A0 (es) | 1986-04-16 |
Family
ID=25642630
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES529232A Expired ES8606494A1 (es) | 1983-01-28 | 1984-01-27 | Un metodo de producir un peptido o polipeptido sintetico. |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0134799B1 (es) |
JP (1) | JPH06225786A (es) |
AU (1) | AU569722B2 (es) |
DE (1) | DE3486110D1 (es) |
DK (1) | DK467484D0 (es) |
ES (1) | ES8606494A1 (es) |
GB (1) | GB2143830B (es) |
GR (1) | GR81750B (es) |
IL (1) | IL70776A (es) |
MY (1) | MY102594A (es) |
NO (1) | NO843872L (es) |
OA (1) | OA07823A (es) |
PT (1) | PT78032B (es) |
SG (1) | SG41089G (es) |
WO (1) | WO1984002917A1 (es) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2145092B (en) * | 1983-01-28 | 1988-04-07 | Univ New York | Protective peptide antigen |
EP0135108A3 (en) * | 1983-08-12 | 1988-07-13 | Rockefeller University | Nucleotide hybridization assay for protozoan parasites |
AU584881B2 (en) * | 1984-02-21 | 1989-06-08 | British Technology Group Limited | Improvements in or relating to the production of malaria vaccines |
IL74409A (en) * | 1984-02-22 | 1994-08-26 | Wellcome Found | Cloning of the p195 gene of p. falciparum and fragments thereof |
US5126264A (en) * | 1984-09-11 | 1992-06-30 | The Walter & Eliza Hall Institute Of Medical Research | The RESA and FIRA antigens of plasmodium falciparum |
IL76338A (en) * | 1984-09-11 | 1994-08-26 | Saramane Pty Ltd | Plasmodium plasmodium immunogenic polypeptides, AND molecules encoding them, a method for preparing the polypeptides and preparations containing the polypeptide |
CN86100979A (zh) * | 1985-02-07 | 1986-12-17 | 史密丝克莱恩贝克曼公司 | 疟疾疫苗的制备方法 |
AU5293486A (en) * | 1985-02-07 | 1986-08-14 | Smithkline Beckman Corporation | Malaria vaccine against plasmodium falciparum |
WO1986004922A1 (en) * | 1985-02-20 | 1986-08-28 | Memorial Sloan-Kettering Cancer Center | cDNA CODING FOR PLASMODIUM FALCIPARUM GLYCOPHORIN BINDING PROTEINS WEIGHING 130,000 DALTONS AND 155,000 DALTONS |
ZW8386A1 (en) * | 1985-04-11 | 1986-07-23 | Inst Medical W & E Hall | Highly repetitive antigens of plasmodium falciparum |
IL79880A0 (en) * | 1985-08-29 | 1986-11-30 | Inst Medical W & E Hall | Recombinant virus |
IL81026A0 (en) * | 1985-12-24 | 1987-03-31 | Inst Medical W & E Hall | Peptides for immunizing against plasmodium falciparum,dna molecules coding for them and compositions containing said peptides |
IL81890A0 (en) * | 1986-03-14 | 1987-10-20 | Saramane Pty Ltd | Polypeptides providing protective immunity against malaria |
US5006514A (en) * | 1986-03-20 | 1991-04-09 | Sawai Pharmaceutical Co., Ltd. | α,α-trehalose trimycolates and pharmaceutical compositions |
FR2610631B1 (fr) * | 1987-02-09 | 1989-11-24 | Pasteur Institut | Molecules comportant au moins une sequence peptidique porteuse d'un ou plusieurs, epitope caracteristique d'une proteine produite par p. falciparum dans les hepatocytes, et leurs utilisations, notamment pour le diagnostic du paludisme ou dans des compositions de vaccins contre le paludisme |
FR2672290B1 (fr) | 1991-02-05 | 1995-04-21 | Pasteur Institut | Sequences peptidiques specifiques des stades hepatiques de p. falciparum porteuses d'epitopes capables de stimuler les lymphocytes t. |
DE3741057A1 (de) * | 1987-03-18 | 1988-09-29 | Behringwerke Ag | Klonierung von malaria-spezifischen dna-sequenzen:isolierung des gens fuer das 140 kd protein |
ZA888983B (en) * | 1987-12-01 | 1989-08-30 | Saramane Pty Ltd | Rhoptry antigen of plasmodium falciparum |
GB2228936A (en) * | 1988-02-12 | 1990-09-12 | Saramane Pty Ltd | Rhoptry membrane antigen of plasmodium falciparum |
GB8819209D0 (en) * | 1988-08-12 | 1988-09-14 | Research Corp Ltd | Polypeptide & dna encoding same |
US5231168A (en) * | 1988-09-16 | 1993-07-27 | Statens Seruminstitut | Malaria antigen |
GB8905857D0 (en) * | 1989-03-14 | 1989-04-26 | Hoffmann La Roche | Plasmodium merozoite rhoptries antigen |
CA2011031C (en) * | 1989-03-14 | 2000-07-18 | Robert George Ridley | Plasmodium merozoite rhoptries antigen and derivatives thereof |
GB9002512D0 (en) * | 1990-02-05 | 1990-04-04 | 3I Res Expl Ltd | Polypeptides and dna encoding same |
KR20020028385A (ko) * | 2000-10-09 | 2002-04-17 | 박제철 | 마커를 이용한 말라리아 원충에 감염된 모기 검출방법 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5434837B2 (es) * | 1972-02-08 | 1979-10-29 | ||
DE3033776A1 (de) * | 1980-09-09 | 1982-04-22 | Behringwerke Ag, 3550 Marburg | Verfahren zur vermehrung von protozoen |
FI64813C (fi) * | 1980-12-31 | 1984-01-10 | Ilkka Antero Palva | Foerfarande foer producering av ett utvalt aeggviteaemne och vid foerfarandet anvaenda rekombinantplasmidvektorer |
GB2145092B (en) * | 1983-01-28 | 1988-04-07 | Univ New York | Protective peptide antigen |
JPS57156421A (en) * | 1981-03-24 | 1982-09-27 | Nippon Koutai Kenkyusho:Kk | Malaria vaccine and its preparation |
IL65496A (en) * | 1981-04-15 | 1985-10-31 | Wellcome Found | Protozoal antigen,its preparation and vaccine containing it |
JPS5810524A (ja) * | 1981-04-15 | 1983-01-21 | ザ・ウエルカム・フアウンデ−シヨン・リミテツド | 保護誘発、蛋白性抗原 |
DE3280028D1 (en) * | 1981-05-21 | 1989-12-28 | Wellcome Found | Protozoal antigen |
GB2099300B (en) * | 1981-05-21 | 1985-02-27 | Wellcome Found | Antigens from parasites of the genus plasmodium |
WO1983002896A1 (en) * | 1982-02-17 | 1983-09-01 | D'antonio, Lawrence, E. | Method for the purification of parasite antigenic factors |
DE3221881A1 (de) * | 1982-06-09 | 1983-12-15 | Münchener Apparatebau Kimmel GmbH, 8012 Ottobrunn | Verfahren zur herstellung eines impfstoffs gegen parasitaere krankheitserreger |
-
1983
- 1983-01-28 AU AU23842/84A patent/AU569722B2/en not_active Ceased
-
1984
- 1984-01-25 IL IL70776A patent/IL70776A/xx not_active IP Right Cessation
- 1984-01-26 GR GR73633A patent/GR81750B/el unknown
- 1984-01-27 DE DE8484900598T patent/DE3486110D1/de not_active Expired - Fee Related
- 1984-01-27 ES ES529232A patent/ES8606494A1/es not_active Expired
- 1984-01-27 WO PCT/AU1984/000016 patent/WO1984002917A1/en active IP Right Grant
- 1984-01-27 EP EP84900598A patent/EP0134799B1/en not_active Expired - Lifetime
- 1984-01-27 PT PT78032A patent/PT78032B/pt unknown
- 1984-01-27 GB GB08424104A patent/GB2143830B/en not_active Expired
- 1984-09-25 OA OA58399A patent/OA07823A/xx unknown
- 1984-09-27 NO NO843872A patent/NO843872L/no unknown
- 1984-09-28 DK DK467484A patent/DK467484D0/da not_active Application Discontinuation
-
1987
- 1987-09-11 MY MYPI87001636A patent/MY102594A/en unknown
-
1989
- 1989-07-07 SG SG410/89A patent/SG41089G/en unknown
-
1993
- 1993-10-27 JP JP5268818A patent/JPH06225786A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0134799A4 (en) | 1985-07-30 |
IL70776A0 (en) | 1984-04-30 |
AU569722B2 (en) | 1988-02-18 |
SG41089G (en) | 1989-12-22 |
OA07823A (en) | 1986-11-20 |
PT78032A (en) | 1984-02-01 |
AU2384284A (en) | 1984-08-09 |
IL70776A (en) | 1991-09-16 |
DE3486110D1 (de) | 1993-04-29 |
DE3486110T2 (es) | 1993-09-09 |
GB2143830A (en) | 1985-02-20 |
GB2143830B (en) | 1987-02-25 |
PT78032B (en) | 1986-03-27 |
DK467484A (da) | 1984-09-28 |
MY102594A (en) | 1992-08-17 |
GR81750B (es) | 1984-12-12 |
NO843872L (no) | 1984-09-27 |
GB8424104D0 (en) | 1984-10-31 |
EP0134799A1 (en) | 1985-03-27 |
JPH06225786A (ja) | 1994-08-16 |
EP0134799B1 (en) | 1993-03-24 |
ES529232A0 (es) | 1986-04-16 |
WO1984002917A1 (en) | 1984-08-02 |
DK467484D0 (da) | 1984-09-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20010301 |