HK1105785A1 - Mammalian-type glycosylation in plants - Google Patents

Mammalian-type glycosylation in plants

Info

Publication number
HK1105785A1
HK1105785A1 HK07111001.7A HK07111001A HK1105785A1 HK 1105785 A1 HK1105785 A1 HK 1105785A1 HK 07111001 A HK07111001 A HK 07111001A HK 1105785 A1 HK1105785 A1 HK 1105785A1
Authority
HK
Hong Kong
Prior art keywords
plants
mammalian
normally
present
plant
Prior art date
Application number
HK07111001.7A
Other languages
English (en)
Inventor
Hendrikus Antonius Cornelis Bakker
Hendrik Jan Bosch
Original Assignee
Stichting Dienst Landbouwkundi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting Dienst Landbouwkundi filed Critical Stichting Dienst Landbouwkundi
Publication of HK1105785A1 publication Critical patent/HK1105785A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1051Hexosyltransferases (2.4.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C12N15/8258Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon for the production of oral vaccines (antigens) or immunoglobulins

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
HK07111001.7A 1999-10-26 2007-10-11 Mammalian-type glycosylation in plants HK1105785A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99203523 1999-10-26
EP99203524 1999-10-26

Publications (1)

Publication Number Publication Date
HK1105785A1 true HK1105785A1 (en) 2008-02-22

Family

ID=26153384

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07111001.7A HK1105785A1 (en) 1999-10-26 2007-10-11 Mammalian-type glycosylation in plants

Country Status (17)

Country Link
US (3) US7781647B2 (fr)
EP (3) EP1772518B1 (fr)
JP (1) JP4890712B2 (fr)
AT (2) ATE478150T1 (fr)
AU (1) AU1738401A (fr)
BR (1) BRPI0015031B1 (fr)
CA (2) CA2389217C (fr)
DE (2) DE60035285T2 (fr)
DK (2) DK1228231T3 (fr)
ES (1) ES2288882T3 (fr)
HK (1) HK1105785A1 (fr)
IL (6) IL149271A0 (fr)
MX (1) MXPA02004142A (fr)
NZ (1) NZ518532A (fr)
PT (2) PT1228231E (fr)
TR (1) TR200201121T2 (fr)
WO (1) WO2001031045A1 (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2350063T3 (es) 1998-12-09 2011-01-17 Phyton Holdings, Llc Método para fabricación de glicoproteínas que tienen glicosilación de tipo humano.
EP1224309A2 (fr) * 1999-10-21 2002-07-24 Monsanto Company Modification post-traductionnelle de proteines de recombinaison produites dans les plantes
DK1228231T3 (da) 1999-10-26 2007-10-29 Plant Res Int Bv Mammal-type glycosylering i planter
JP5623683B2 (ja) * 2000-03-22 2014-11-12 フィトン ホールディングス,リミティド ライアビリティ カンパニー 動物型糖鎖付加機能をもつ植物細胞
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
US7632983B2 (en) * 2000-07-31 2009-12-15 Biolex Therapeutics, Inc. Expression of monoclonal antibodies in duckweed
US8022270B2 (en) 2000-07-31 2011-09-20 Biolex Therapeutics, Inc. Expression of biologically active polypeptides in duckweed
JP2005505234A (ja) 2001-01-19 2005-02-24 ザ ダウ ケミカル カンパニー 植物細胞によるヒト型糖鎖をもつ糖タンパク質の分泌生産方法
EP1367881A2 (fr) * 2001-03-06 2003-12-10 The Dow Chemical Company Cellule vegetale comportant une fonction d'addition de chaine de sucres de type animal
GB2377446B (en) * 2001-07-13 2005-06-29 Lars Erik Berglund Expression of cobalamin binding proteins in transgenic plants
AU2013205262B2 (en) * 2002-03-19 2016-02-25 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
AU2008202355B2 (en) * 2002-03-19 2011-04-07 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
AU2003219418B2 (en) * 2002-03-19 2008-02-28 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
US7897842B2 (en) * 2002-03-19 2011-03-01 Plant Research International B.V. GnTIII expression in plants
AR042145A1 (es) * 2002-11-27 2005-06-08 Dow Agrociences Llc Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
ES2542885T3 (es) * 2003-01-22 2015-08-12 Roche Glycart Ag Constructos de fusión y uso de los mismos para producir anticuerpos con mayor afinidad de unión al receptor de Fc y función efectora
EP1536229A1 (fr) * 2003-11-26 2005-06-01 Plant Research International B.V. Méthode pour identifier un profil biomoleculair
CN104611245A (zh) * 2004-04-15 2015-05-13 格利科菲公司 在低等真核生物中产生半乳糖基化糖蛋白
CA2567952C (fr) 2004-05-31 2016-02-02 The Kitasato Institute Vaccins oraux antiprotozoaires a base de plantes transgeniques
CA2570566A1 (fr) * 2004-06-25 2006-01-12 Altor Bioscience Corporation Production d'un facteur tissulaire chez des plantes
JP2006288210A (ja) 2005-04-05 2006-10-26 National Institute Of Advanced Industrial & Technology 糖転移酵素遺伝子の導入による生体内糖鎖伸長の技術
AU2006268851B2 (en) * 2005-07-12 2011-06-30 Greenovation Biotech Gmbh Improvements in or relating to protein production
CA2637252A1 (fr) 2006-01-17 2007-07-26 Biolex Therapeutics, Inc. Plantes et cellules vegetales dont l'expression de la a(1,3)-fucosyl-transferase et de la b(1,2)-xylosyltransferase est inhibee
JP5502328B2 (ja) * 2006-02-09 2014-05-28 メディカゴ インコーポレイテッド 植物体中でのシアル酸の合成
EP1878747A1 (fr) 2006-07-11 2008-01-16 greenovation Biotech GmbH Anticorps glyco-modifiés
BRPI0810443A2 (pt) * 2007-04-17 2016-09-27 Plant Res Int Bv glicosilação do tipo em mamífero em plantas através da expressão de glicosiltransferases de não mamíferos
AU2013203379B2 (en) * 2007-04-17 2016-01-21 Stichting Dienst Landbouwkundig Onderzoek Mammalian-type glycosylation in plants by expression of non-mammalian glycosyltransferases
AU2008253212A1 (en) * 2007-05-21 2008-11-27 Bayer Bioscience N.V. Methods and means for producing glycoproteins with altered glycosylation pattern in higher plants
PL2155880T3 (pl) * 2007-06-15 2017-06-30 Medicago Inc. Modyfikacja wytwarzania glikoproteiny w roślinach
CN102165062B (zh) 2008-07-18 2017-09-08 麦迪卡格公司 新的流感病毒免疫表位
US8232073B2 (en) 2009-01-02 2012-07-31 Zacharon Pharmaceuticals, Inc. Quantification of non-reducing end glycan residual compounds
US9029530B2 (en) 2009-01-02 2015-05-12 Biomarin Pharmaceutical Inc. Detection of oligosaccharides
US8809009B2 (en) 2009-01-02 2014-08-19 Biomarin Pharmaceutical Inc. Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker
EP2411529A4 (fr) * 2009-03-27 2012-09-19 Zacharon Pharmaceuticals Inc Modulateurs de la biosynthèse des glycanes n-liés
US8846373B2 (en) 2011-07-29 2014-09-30 The University Of Wyoming Methods of using a bacterial GlcNAc-6-P 2′- epimerase to promote sialylation of glycoconjugates
US9816107B2 (en) 2011-07-29 2017-11-14 The University Of Wyoming Transgenic insect cells comprising a bacterial GlcNAc-6-P 2′-epimerase
WO2013119419A1 (fr) 2012-02-08 2013-08-15 North Carolina State University Traitement de maladies allergiques avec des anticorps recombinants
US20140115728A1 (en) 2012-10-24 2014-04-24 A. Joseph Tector Double knockout (gt/cmah-ko) pigs, organs and tissues
EP3538558A4 (fr) 2016-11-09 2020-07-15 North Carolina State University Traitement de maladies allergiques au moyen d'une protéine chimérique
WO2018098572A1 (fr) 2016-12-01 2018-06-07 Plantform Corporation Plante transgénique à activité fucosyltransférase et xylosyltransférase réduite
JP6934666B2 (ja) * 2018-01-18 2021-09-15 国立研究開発法人産業技術総合研究所 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法
WO2019183437A1 (fr) 2018-03-23 2019-09-26 North Carolina State University Procédés et compositions pour un anticorps dirigé contre un récepteur ige de haute affinité
USD1034550S1 (en) * 2022-12-19 2024-07-09 Shenzhen Xunweijia Technology Development Co., Ltd. Microphone
USD1034549S1 (en) * 2022-12-19 2024-07-09 Shenzhen Xunweijia Technology Development Co., Ltd. Microphone

Family Cites Families (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5455790A (en) 1977-10-05 1979-05-04 Tomoyuki Tajima Production of erythropoetin
JPS5616496A (en) 1979-07-20 1981-02-17 Sumitomo Chem Co Ltd Recovery of erythropoietin
JPS5653696A (en) 1979-10-09 1981-05-13 Ajinomoto Co Inc Isolation of erythropoietin by adsorption
JPS56108798A (en) 1980-02-01 1981-08-28 Green Cross Corp:The Purification of erythropoietin
JPS57149228A (en) 1981-03-11 1982-09-14 Ajinomoto Co Inc Novel erythropoietin and its preparation
JPS57169424A (en) 1981-04-10 1982-10-19 Toyo Shinyaku Kk Preparation of erythropoietin
US4956282A (en) * 1985-07-29 1990-09-11 Calgene, Inc. Mammalian peptide expression in plant cells
US5179198A (en) 1988-07-11 1993-01-12 Hidechika Okada Glycoprotein and gene coding therefor
US5202422A (en) 1989-10-27 1993-04-13 The Scripps Research Institute Compositions containing plant-produced glycopolypeptide multimers, multimeric proteins and method of their use
US5959177A (en) 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
WO1991016449A1 (fr) 1990-04-16 1991-10-31 The Trustees Of The University Of Pennsylvania Compositions saccharides et procedes et appareil servant a les synthetiser
ATE210150T1 (de) 1991-04-18 2001-12-15 Toray Industries Verfahren zur herstellung von interleukin-6 zusammensetzungen
US5874271A (en) 1992-08-21 1999-02-23 Takara Shuzo Co., Ltd. Human glycosyltransferase gene, compounds and method for inhibiting cancerous metastasis
JPH08503373A (ja) 1992-11-27 1996-04-16 チバ−ガイギー アクチェンゲゼルシャフト グリコシルトランスフェラーゼ活性を有するタンパク質
WO1995002683A1 (fr) 1993-07-15 1995-01-26 Neose Pharmaceuticals Procede de synthese de compositions de saccharide
WO1995018217A1 (fr) 1993-12-24 1995-07-06 The Institute Of Physical And Chemical Research Nouvelle synthetase a chaine de sucres, et procede pour produire cette derniere
JP2854803B2 (ja) * 1994-04-28 1999-02-10 理化学研究所 新規糖鎖合成酵素
JP2839232B2 (ja) * 1993-12-24 1998-12-16 理化学研究所 新規糖鎖合成酵素
WO1995021248A1 (fr) * 1994-02-03 1995-08-10 The Scripps Research Institute Procede d'utilisation du virus de la mosaique du tabac pour surproduire des peptides et des proteines
US5723755A (en) * 1995-05-16 1998-03-03 Francis E. Lefaivre Large scale production of human or animal proteins using plant bioreactors
US5939288A (en) 1995-06-07 1999-08-17 Iowa State University Research Foundation, Inc. Plant secretory signal peptides and nectarins
FR2736930B1 (fr) 1995-07-17 1997-09-19 Biocem Procede de production, par des cellules vegetales, de proteines heminiques, proteines ainsi obtenues et produits contenant ces proteines
AU6504796A (en) 1995-07-20 1997-02-18 Washington State University Research Foundation Production of secreted foreign polypeptides in plant cell culture
EP0816503B1 (fr) 1996-01-24 2006-07-05 Toyo Boseki Kabushiki Kaisha Alpha-1-6 fucosyltransferases
CA2233705A1 (fr) 1996-08-02 1998-02-12 The Austin Research Institute Acides nucleiques ameliores codant une glycosyltransferase chimere
DE69823046T2 (de) 1997-01-16 2005-03-31 Neose Technologies, Inc. Praktische in vitro sialylierung von rekombinanten glykpproteinen
US6087115A (en) 1997-01-22 2000-07-11 Cornell Research Foundation, Inc. Methods of identifying negative antagonists for G protein coupled receptors
JP3921271B2 (ja) 1997-05-16 2007-05-30 生化学工業株式会社 グルクロン酸転移酵素をコードするdna
JP4003093B2 (ja) 1997-07-29 2007-11-07 東洋紡績株式会社 糖類の製造方法
AU1585999A (en) 1997-11-12 1999-05-31 Neurotherapeutics Methods for the detection and treatment of disease using a glycosyltransferase
DE19754622A1 (de) 1997-12-09 1999-06-10 Antje Von Dr Schaewen Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität
US6096546A (en) 1998-01-30 2000-08-01 Board Of Trustees, Rutgers, The State University Of New Jersey Methods for recovering polypeptides from plants and portions thereof
FR2774379B1 (fr) 1998-01-30 2002-03-29 Groupe Limagrain Holding Procede de production, par des cellules vegetales, d'alpha 1-antitrypsine et de ses variantes, et produits contenant l'alpha-antitrypsine ainsi obtenue
US5955282A (en) * 1998-04-03 1999-09-21 Incyte Pharmaceuticals, Inc. Human galactosyltransferases
US20030175884A1 (en) 2001-08-03 2003-09-18 Pablo Umana Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
AU3657899A (en) 1998-04-20 1999-11-08 James E. Bailey Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity
IL126967A (en) 1998-11-09 2002-09-12 Lightech Electronics Ind Ltd Electronic transformer for lighting
JP2002530087A (ja) 1998-11-18 2002-09-17 ネオーズ テクノロジーズ, インコーポレイテッド オリゴ糖の安価な産生
ES2350063T3 (es) 1998-12-09 2011-01-17 Phyton Holdings, Llc Método para fabricación de glicoproteínas que tienen glicosilación de tipo humano.
AT408446B (de) 1999-02-18 2001-11-26 Altmann Friedrich Dr Fucosyltransferase-gen
JP2000245470A (ja) 1999-02-26 2000-09-12 Noda Inst For Scient Res 植物細胞間液による外来ポリペプチドの製造方法
JP2002537796A (ja) 1999-03-02 2002-11-12 ヒューマン ジノーム サイエンシーズ, インコーポレイテッド ヒトグリコシル化酵素
JP2000287692A (ja) 1999-04-09 2000-10-17 Mitsui Chemicals Inc 糖タンパク質の有するn−結合型糖鎖の組成中、分岐数が異なる糖鎖の含有割合を制御する方法
BR0014858A (pt) 1999-10-15 2002-07-16 Calgene Llc Métodos e vetores para recombinação de sìtio especìfico em plastìdios de células de plantas
EP1224309A2 (fr) * 1999-10-21 2002-07-24 Monsanto Company Modification post-traductionnelle de proteines de recombinaison produites dans les plantes
DK1228231T3 (da) 1999-10-26 2007-10-29 Plant Res Int Bv Mammal-type glycosylering i planter
WO2001031044A1 (fr) 1999-10-26 2001-05-03 Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. Gonadotrophines dans les plantes
JP2001546898A (en) 1999-12-21 2003-06-10 Kyowa Hakko Kogyo Kk MODIFIED alpha -1,2-FUCOSYLTRANSFERASE GENE AND PROCESS FOR PRODUCING alpha -1,2-FUCOSYLTRANSFERASE AND FUCOSE-CONTAINING SUGAR CHAIN
DE60044038D1 (de) 1999-12-30 2010-04-29 Knut Kleesiek Xylosyltransferase und isoformen
FR2803307A1 (fr) 1999-12-30 2001-07-06 Centre Nat Rech Scient Lignees de lymphocytes t cd4 specifiques de type th1 et procede pour leur induction ex vivo
AU2001235285A1 (en) 2000-02-24 2001-09-03 University Of Guelph Method of modulating glycosylation pathways
US20020174453A1 (en) 2001-04-18 2002-11-21 Henry Daniell Production of antibodies in transgenic plastids
AT409381B (de) 2000-03-03 2002-07-25 Gloessl Josef Dr Xylosyltransferase-gen
FR2808286B1 (fr) 2000-04-26 2004-12-17 Agronomique Inst Nat Rech Nouvelle glucosidase i de plante et son application a la production de proteines recombinantes a glycosylation modifiee
AU2001250573A1 (en) 2000-04-28 2001-11-12 Michel Xilinas Treatment of pathological conditions influenced by the action of matrix metalloproteinases (mmps) using phanquinone
WO2001088117A2 (fr) 2000-05-12 2001-11-22 Neose Technologies, Inc. Modification in vitro de motifs de glycosylation de glycopeptides recombines
DK1522590T3 (da) 2000-06-28 2009-12-21 Glycofi Inc Fremgangsmåde til fremstilling af modificerede glykoproteiner
AU2002222965A1 (en) 2000-07-19 2002-01-30 Digimarc Corporation Print media with embedded messages for controlling printing
TW519716B (en) * 2000-12-19 2003-02-01 Tokyo Electron Ltd Wafer bias drive for a plasma source
JP2005505234A (ja) 2001-01-19 2005-02-24 ザ ダウ ケミカル カンパニー 植物細胞によるヒト型糖鎖をもつ糖タンパク質の分泌生産方法
EP1367881A2 (fr) 2001-03-06 2003-12-10 The Dow Chemical Company Cellule vegetale comportant une fonction d'addition de chaine de sucres de type animal
WO2003001187A1 (fr) 2001-06-22 2003-01-03 Siemens Building Technologies Ag Systeme video-detecteur de fumee et procede de verification
WO2003007661A1 (fr) 2001-07-09 2003-01-23 Ibiden Co., Ltd. Appareil de chauffage en ceramique et article en ceramique soude
SE519261C2 (sv) 2001-07-17 2003-02-04 Sca Hygiene Prod Ab Absorberande alster
WO2003007861A1 (fr) 2001-07-20 2003-01-30 Cutmed Ltd. Systeme pour realiser une operation de micro-forage chez un homme ou un animal et son procede d'utilisation
US20030175755A1 (en) 2002-03-05 2003-09-18 Yoshihiro Abiko Method of collecting data for estimation of susceptibility to periodontal disease
AU2003219418B2 (en) 2002-03-19 2008-02-28 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
US7897842B2 (en) 2002-03-19 2011-03-01 Plant Research International B.V. GnTIII expression in plants
DE10229635C1 (de) 2002-07-02 2003-07-10 Ise Gmbh Überrollschutzsystem für Kraftfahrzeuge
AR042145A1 (es) 2002-11-27 2005-06-08 Dow Agrociences Llc Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
AU2006268851B2 (en) * 2005-07-12 2011-06-30 Greenovation Biotech Gmbh Improvements in or relating to protein production
BRPI0810443A2 (pt) 2007-04-17 2016-09-27 Plant Res Int Bv glicosilação do tipo em mamífero em plantas através da expressão de glicosiltransferases de não mamíferos

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IL212888A0 (en) 2011-07-31
WO2001031045A1 (fr) 2001-05-03
TR200201121T2 (tr) 2003-01-21
EP1228231B1 (fr) 2007-06-20
PT1228231E (pt) 2007-09-25
US8193415B2 (en) 2012-06-05
AU1738401A (en) 2001-05-08
PT1772518E (pt) 2010-10-28
US20110030108A1 (en) 2011-02-03
NZ518532A (en) 2004-02-27
ES2288882T3 (es) 2008-02-01
JP4890712B2 (ja) 2012-03-07
DK1772518T3 (da) 2010-11-22
IL212889A0 (en) 2011-07-31
IL204883A (en) 2012-05-31
DK1228231T3 (da) 2007-10-29
EP2251426A1 (fr) 2010-11-17
US8907163B2 (en) 2014-12-09
BR0015031A (pt) 2002-06-18
EP1772518A3 (fr) 2007-04-18
CA2389217C (fr) 2016-12-06
ATE478150T1 (de) 2010-09-15
DE60035285T2 (de) 2008-02-21
DE60044858D1 (de) 2010-09-30
CA2925231A1 (fr) 2001-05-03
IL149271A (en) 2010-11-30
US20120237972A1 (en) 2012-09-20
IL212888A (en) 2017-12-31
CA2389217A1 (fr) 2001-05-03
EP1772518A2 (fr) 2007-04-11
MXPA02004142A (es) 2003-08-20
US7781647B2 (en) 2010-08-24
DE60035285D1 (de) 2007-08-02
IL212887A0 (en) 2011-07-31
EP1772518B1 (fr) 2010-08-18
IL149271A0 (en) 2002-11-10
JP2003512076A (ja) 2003-04-02
US20080003680A1 (en) 2008-01-03
ATE365219T1 (de) 2007-07-15
EP1228231A1 (fr) 2002-08-07

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