HK1100922A1 - Method for the separation of intermediates which may be used for the preparation of escitalopram - Google Patents

Method for the separation of intermediates which may be used for the preparation of escitalopram

Info

Publication number
HK1100922A1
HK1100922A1 HK07108652.5A HK07108652A HK1100922A1 HK 1100922 A1 HK1100922 A1 HK 1100922A1 HK 07108652 A HK07108652 A HK 07108652A HK 1100922 A1 HK1100922 A1 HK 1100922A1
Authority
HK
Hong Kong
Prior art keywords
escitalopram
intermediates
separation
preparation
Prior art date
Application number
HK07108652.5A
Other languages
English (en)
Inventor
Lars Ole Lyngsoe
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36603240&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1100922(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of HK1100922A1 publication Critical patent/HK1100922A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/32—Separation; Purification; Stabilisation; Use of additives
    • C07C253/34—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/53—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK07108652.5A 2004-02-12 2007-08-09 Method for the separation of intermediates which may be used for the preparation of escitalopram HK1100922A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200400217 2004-02-12
PCT/DK2005/000075 WO2005077891A1 (en) 2004-02-12 2005-02-02 Method for the separation of intermediates which may be used for the preparation of escitalopram

Publications (1)

Publication Number Publication Date
HK1100922A1 true HK1100922A1 (en) 2007-10-05

Family

ID=36603240

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07108652.5A HK1100922A1 (en) 2004-02-12 2007-08-09 Method for the separation of intermediates which may be used for the preparation of escitalopram

Country Status (27)

Country Link
US (1) US7582780B2 (xx)
EP (1) EP1716108B1 (xx)
JP (1) JP4975450B2 (xx)
KR (1) KR101156495B1 (xx)
CN (1) CN1918112B (xx)
AR (1) AR047522A1 (xx)
AT (1) ATE411278T1 (xx)
AU (1) AU2005212455A1 (xx)
BR (1) BRPI0507580B8 (xx)
CA (1) CA2555980C (xx)
DK (1) DK1716108T3 (xx)
EA (1) EA012503B1 (xx)
ES (1) ES2315832T3 (xx)
HK (1) HK1100922A1 (xx)
IL (1) IL177365A0 (xx)
MY (1) MY144749A (xx)
NZ (1) NZ548441A (xx)
PE (1) PE20051139A1 (xx)
PL (1) PL1716108T3 (xx)
PT (1) PT1716108E (xx)
RS (1) RS50689B (xx)
SI (1) SI1716108T1 (xx)
TW (1) TWI339651B (xx)
UA (1) UA86403C2 (xx)
UY (1) UY28743A1 (xx)
WO (1) WO2005077891A1 (xx)
ZA (1) ZA200606639B (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100548974C (zh) * 2007-10-11 2009-10-14 浙江大学 西酞普兰中间体的萃取分离方法
CN108640856B (zh) * 2018-06-11 2021-06-25 淮阴工学院 一种依地普仑中间体的不对称合成方法及其中间体

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
WO2000023431A1 (en) 1998-10-20 2000-04-27 H. Lundbeck A/S Method for the preparation of citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991486A1 (it) 1999-07-06 2001-01-06 Vis Farmaceutici S P A Processo per la sintesi di citalopram
EP1228056B1 (en) 1999-10-25 2004-09-22 H. Lundbeck A/S Method for the preparation of citalopram
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NZ521201A (en) 2000-03-13 2004-02-27 H Method for the preparation of citalopram
EP1265881A1 (en) 2000-03-13 2002-12-18 H. Lundbeck A/S Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
IL151488A0 (en) 2000-03-14 2003-04-10 Lundbeck & Co As H Method for the preparation of citalopram
EA200200982A1 (ru) 2000-03-16 2003-02-27 Х.Лундбекк А/С Способ получения 5-циано-1-(4-фторфенил)-1,3-дигидроизобензофуранов
AR034612A1 (es) 2001-06-25 2004-03-03 Lundbeck & Co As H Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
AR034759A1 (es) * 2001-07-13 2004-03-17 Lundbeck & Co As H Metodo para la preparacion de escitalopram
IL159326A0 (en) * 2001-07-31 2004-06-01 Lundbeck & Co As H Crystalline composition containing escitalopram
IS7239A (is) * 2001-12-14 2004-04-29 H. Lundbeck A/S Aðferð til framleiðslu á essítalóprami
ES2194597B2 (es) * 2002-01-25 2004-08-01 Esteve Quimica, S.A. Procedimiento para la obtencion de citalopram.
GB0204607D0 (en) * 2002-02-27 2002-04-10 Matrix Lab Ltd Process
CA2381341A1 (en) * 2002-04-09 2003-10-09 Torcan Chemical Ltd. Process and intermediates for preparing escitalopram
PE20040991A1 (es) * 2002-08-12 2004-12-27 Lundbeck & Co As H Separacion de intermediarios para la preparacion de escitalopram
EP1581483B1 (en) * 2002-12-23 2012-06-06 H. Lundbeck A/S A PROCESS FOR THE PREPARATION OF RACEMIC CITALOPRAM DIOL AND/OR i S- /i OR i R- /i CITALOPRAM DIOLS AND THE USE OF SUCH DIOLS FOR THE PREPARATION OF RACEMIC CITALOPRAM, i R- /i CITALOPRAM AND/OR i S- /i CITALOPRAM

Also Published As

Publication number Publication date
SI1716108T1 (sl) 2009-02-28
PL1716108T3 (pl) 2009-04-30
EA200601469A1 (ru) 2006-12-29
CN1918112A (zh) 2007-02-21
PE20051139A1 (es) 2006-01-28
EP1716108A1 (en) 2006-11-02
WO2005077891A1 (en) 2005-08-25
RS50689B (sr) 2010-06-30
EA012503B1 (ru) 2009-10-30
ES2315832T3 (es) 2009-04-01
ATE411278T1 (de) 2008-10-15
BRPI0507580B8 (pt) 2021-05-25
CN1918112B (zh) 2011-11-23
TW200530210A (en) 2005-09-16
PT1716108E (pt) 2008-12-31
EP1716108B1 (en) 2008-10-15
US7582780B2 (en) 2009-09-01
CA2555980C (en) 2010-08-03
BRPI0507580B1 (pt) 2018-01-09
US20070190624A1 (en) 2007-08-16
AR047522A1 (es) 2006-01-25
KR101156495B1 (ko) 2012-07-06
BRPI0507580A (pt) 2007-07-31
JP4975450B2 (ja) 2012-07-11
MY144749A (en) 2011-10-31
CA2555980A1 (en) 2005-08-25
AU2005212455A1 (en) 2005-08-25
IL177365A0 (en) 2006-12-10
KR20060116222A (ko) 2006-11-14
UY28743A1 (es) 2005-09-30
UA86403C2 (uk) 2009-04-27
DK1716108T3 (da) 2009-01-19
TWI339651B (en) 2011-04-01
NZ548441A (en) 2009-12-24
ZA200606639B (en) 2007-12-27
JP2007524678A (ja) 2007-08-30

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