PL1622926T3 - Nowy sposób i produkty pośrednie wytwarzania związków 19-norsteroidów fluorowcowanych w pozycji 17 - Google Patents

Nowy sposób i produkty pośrednie wytwarzania związków 19-norsteroidów fluorowcowanych w pozycji 17

Info

Publication number
PL1622926T3
PL1622926T3 PL04742578T PL04742578T PL1622926T3 PL 1622926 T3 PL1622926 T3 PL 1622926T3 PL 04742578 T PL04742578 T PL 04742578T PL 04742578 T PL04742578 T PL 04742578T PL 1622926 T3 PL1622926 T3 PL 1622926T3
Authority
PL
Poland
Prior art keywords
steroids
intermediates
preparation
novel method
halogen compounds
Prior art date
Application number
PL04742578T
Other languages
English (en)
Inventor
François Nique
Christian Moratille
Patrick Roussel
Joelle Bousquet
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of PL1622926T3 publication Critical patent/PL1622926T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
PL04742578T 2003-04-29 2004-04-27 Nowy sposób i produkty pośrednie wytwarzania związków 19-norsteroidów fluorowcowanych w pozycji 17 PL1622926T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0305222A FR2854403B1 (fr) 2003-04-29 2003-04-29 Nouveau procede et intermediaires de preparation de composes 19-nor-steroides 17-halogenes
EP04742578A EP1622926B1 (fr) 2003-04-29 2004-04-27 Nouveau procede et intermediaires de preparation de composes 19-nor-stero des-17-halogenes
PCT/FR2004/001011 WO2004096829A2 (fr) 2003-04-29 2004-04-27 Nouveau procede et intermediaires de preparation de composes 19-nor-steroïdes-17-halogenes

Publications (1)

Publication Number Publication Date
PL1622926T3 true PL1622926T3 (pl) 2009-12-31

Family

ID=33155513

Family Applications (1)

Application Number Title Priority Date Filing Date
PL04742578T PL1622926T3 (pl) 2003-04-29 2004-04-27 Nowy sposób i produkty pośrednie wytwarzania związków 19-norsteroidów fluorowcowanych w pozycji 17

Country Status (15)

Country Link
US (1) US7449572B2 (pl)
EP (1) EP1622926B1 (pl)
JP (1) JP4629030B2 (pl)
AR (1) AR044103A1 (pl)
AT (1) ATE435869T1 (pl)
CY (1) CY1109434T1 (pl)
DE (1) DE602004021918D1 (pl)
DK (1) DK1622926T3 (pl)
ES (1) ES2328927T3 (pl)
FR (1) FR2854403B1 (pl)
PL (1) PL1622926T3 (pl)
PT (1) PT1622926E (pl)
SI (1) SI1622926T1 (pl)
TW (1) TW200510448A (pl)
WO (1) WO2004096829A2 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2854402B1 (fr) * 2003-04-29 2008-07-04 Aventis Pharma Sa Nouveau procede et intermediaires de preparation de composes 19-nor-steroides
HU227112B1 (hu) * 2006-06-14 2010-07-28 Richter Gedeon Nyrt Ipari eljárás 17-alfa-acetoxi-11-béta-[4-(N,N-dimetil-amino)-fenil]-19-norpregna-4,9-dién-3,20-dion elõállítására és új intermedierek az eljáráshoz
CA2933590C (en) 2013-12-11 2023-10-03 Sloan-Kettering Institute For Cancer Research Glucocorticoid inhibitors for treatment of prostate cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3264327A (en) * 1962-07-27 1966-08-02 Syntex Corp 17alpha-fluoro-, 17beta-chlorofluoroacetoxy- and 17beta-methyl-delta4-and delta5-androstene derivatives
FR2528434B1 (fr) * 1982-06-11 1985-07-19 Roussel Uclaf Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament
FR2640977A2 (en) * 1982-06-11 1990-06-29 Roussel Uclaf New position-11 substituted 19-norsteroids and their application as medicinal products.
FR2771096B1 (fr) * 1997-11-17 2000-08-11 Hoechst Marion Roussel Inc Nouveaux 19-nor steroides, substitues en position 11beta, procede et intermediaires de preparation, application comme medicaments et compositions pharmaceutiques les renfermant
FR2780060B1 (fr) * 1998-06-23 2000-08-04 Hoechst Marion Roussel Inc Nouveaux 19-nor steroides 17-halogenes, procede et intermediaires de preparation, application comme medicaments et compositions pharmaceutiques les renfermant
FR2854402B1 (fr) * 2003-04-29 2008-07-04 Aventis Pharma Sa Nouveau procede et intermediaires de preparation de composes 19-nor-steroides

Also Published As

Publication number Publication date
PT1622926E (pt) 2009-09-07
CY1109434T1 (el) 2014-08-13
FR2854403A1 (fr) 2004-11-05
SI1622926T1 (sl) 2009-12-31
JP2006525290A (ja) 2006-11-09
WO2004096829A3 (fr) 2005-02-03
WO2004096829A2 (fr) 2004-11-11
ES2328927T3 (es) 2009-11-19
AR044103A1 (es) 2005-08-24
US7449572B2 (en) 2008-11-11
JP4629030B2 (ja) 2011-02-09
US20040224933A1 (en) 2004-11-11
DE602004021918D1 (de) 2009-08-20
FR2854403B1 (fr) 2008-07-11
EP1622926B1 (fr) 2009-07-08
EP1622926A2 (fr) 2006-02-08
DK1622926T3 (da) 2009-11-16
TW200510448A (en) 2005-03-16
ATE435869T1 (de) 2009-07-15

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