HK1098122A1 - Stereoselective synthesis of vitamin d analogues - Google Patents

Stereoselective synthesis of vitamin d analogues

Info

Publication number
HK1098122A1
HK1098122A1 HK07104320.6A HK07104320A HK1098122A1 HK 1098122 A1 HK1098122 A1 HK 1098122A1 HK 07104320 A HK07104320 A HK 07104320A HK 1098122 A1 HK1098122 A1 HK 1098122A1
Authority
HK
Hong Kong
Prior art keywords
analogues
vitamin
stereoselective synthesis
stereoselective
synthesis
Prior art date
Application number
HK07104320.6A
Other languages
English (en)
Inventor
Thomas Peter Sabroe
Martin John Calverley
Original Assignee
Leo Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharma As filed Critical Leo Pharma As
Publication of HK1098122A1 publication Critical patent/HK1098122A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/72—Benzo[c]thiophenes; Hydrogenated benzo[c]thiophenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK07104320.6A 2004-03-18 2007-04-24 Stereoselective synthesis of vitamin d analogues HK1098122A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US55396204P 2004-03-18 2004-03-18
DKPA200400454 2004-03-22
PCT/DK2005/000161 WO2005087719A1 (en) 2004-03-18 2005-03-10 Stereoselective synthesis of vitamin d analogues

Publications (1)

Publication Number Publication Date
HK1098122A1 true HK1098122A1 (en) 2007-07-13

Family

ID=34961016

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07104320.6A HK1098122A1 (en) 2004-03-18 2007-04-24 Stereoselective synthesis of vitamin d analogues

Country Status (18)

Country Link
EP (1) EP1730108B1 (de)
JP (1) JP4667450B2 (de)
KR (1) KR100859277B1 (de)
CN (1) CN1934078B (de)
AR (1) AR048274A1 (de)
AT (1) ATE390411T1 (de)
BR (1) BRPI0507318A (de)
CA (1) CA2555260C (de)
CY (1) CY1108156T1 (de)
DE (2) DE602005005645T2 (de)
ES (1) ES2304686T3 (de)
HK (1) HK1098122A1 (de)
IL (1) IL176718A (de)
PL (1) PL1730108T3 (de)
RU (1) RU2380359C2 (de)
SI (1) SI1730108T1 (de)
TW (1) TWI324063B (de)
WO (1) WO2005087719A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4744507B2 (ja) * 2004-04-02 2011-08-10 レオ ファーマ アクティーゼルスカブ ビタミンｄ類似体の合成に有用な中間体の新規製造法
CA2646856C (en) 2006-03-17 2013-05-07 Leo Pharma A/S Isomerisation of pharmaceutical intermediates
US8013189B2 (en) * 2007-09-21 2011-09-06 Basf Se Accelerated amide and ester reductions with amine boranes and additives
US8716334B2 (en) * 2008-06-17 2014-05-06 Ben Gurion University Of The Negev Research And Development Authority Substituted cyclohexylidene-ethylidene-octahydro-indene compounds
CN103265528B (zh) * 2013-05-10 2015-05-06 湖南千金湘江药业股份有限公司 埃索美拉唑镁的制备方法
CN106908524B (zh) * 2015-12-23 2021-05-04 重庆华邦胜凯制药有限公司 卡泊三醇中间体l及其潜在基因毒性杂质的分离与测定方法
CN107643354B (zh) * 2016-07-22 2022-02-01 重庆华邦胜凯制药有限公司 卡泊三醇起始原料a及相关杂质的分离与测定方法
ES2945426B2 (es) * 2021-12-30 2024-01-22 Laboratorios Vinas S A Procedimiento para obtener epímeros 24S a partir de derivados de vitaminas D y procedimiento de obtención de vitaminas D relacionado

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987000834A1 (en) * 1985-08-02 1987-02-12 Leo Pharmaceutical Products Ltd. A/S Novel vitamin d analogues
JPH075542B2 (ja) * 1988-09-14 1995-01-25 呉羽化学工業株式会社 ビタミンｄ▲下３▼誘導体及びその製造方法
US5247104A (en) * 1992-11-04 1993-09-21 Wisconsin Alumni Research Foundation Preparation of 1α, 24-dihydroxyvitamin D analogs
US5449668A (en) * 1993-06-04 1995-09-12 Duphar International Research B.V. Vitamin D compounds and method of preparing these compounds
GB9524812D0 (en) * 1995-12-05 1996-02-07 Leo Pharm Prod Ltd Chemical compounds
GB9622590D0 (en) * 1996-10-30 1997-01-08 Leo Pharm Prod Ltd Chemical compounds
US6262283B1 (en) * 1996-12-06 2001-07-17 Magainin Pharmaceuticals Inc. Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds
AU758792B2 (en) * 1998-10-23 2003-03-27 Teijin Limited Vitamin D3 derivatives and remedies for inflammatory respiratory diseases containing the same

Also Published As

Publication number Publication date
ES2304686T3 (es) 2008-10-16
EP1730108A1 (de) 2006-12-13
JP4667450B2 (ja) 2011-04-13
CA2555260C (en) 2011-12-06
CN1934078A (zh) 2007-03-21
KR100859277B1 (ko) 2008-09-19
ATE390411T1 (de) 2008-04-15
KR20060134045A (ko) 2006-12-27
CN1934078B (zh) 2011-07-06
CA2555260A1 (en) 2005-09-22
BRPI0507318A (pt) 2007-06-26
DE602005005645T2 (de) 2009-06-18
AR048274A1 (es) 2006-04-12
CY1108156T1 (el) 2014-02-12
DE05706821T1 (de) 2008-02-07
TW200539866A (en) 2005-12-16
IL176718A (en) 2007-07-04
EP1730108B1 (de) 2008-03-26
TWI324063B (en) 2010-05-01
WO2005087719A1 (en) 2005-09-22
PL1730108T3 (pl) 2008-09-30
DE602005005645D1 (de) 2008-05-08
RU2380359C2 (ru) 2010-01-27
RU2006129922A (ru) 2008-02-27
JP2007529433A (ja) 2007-10-25
SI1730108T1 (sl) 2008-08-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230310