HK1096971A1 - Processes for preparing bicyclo[3.1.0] hexane derivatives, and intermediates thereto - Google Patents

Processes for preparing bicyclo[3.1.0] hexane derivatives, and intermediates thereto

Info

Publication number
HK1096971A1
HK1096971A1 HK07104000.3A HK07104000A HK1096971A1 HK 1096971 A1 HK1096971 A1 HK 1096971A1 HK 07104000 A HK07104000 A HK 07104000A HK 1096971 A1 HK1096971 A1 HK 1096971A1
Authority
HK
Hong Kong
Prior art keywords
intermediates
processes
hexane derivatives
preparing bicyclo
bicyclo
Prior art date
Application number
HK07104000.3A
Other languages
English (en)
Inventor
Frederick W Hartner
Lushi Tan
Nobuyoshi Yasuda
Naoki Yoshikawa
Original Assignee
Taisho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co Ltd filed Critical Taisho Pharmaceutical Co Ltd
Publication of HK1096971A1 publication Critical patent/HK1096971A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/08—Saturated compounds having a carboxyl group bound to a six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/50—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms being part of the same condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/74—Esters of carboxylic acids having an esterified carboxyl group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/04—Compounds containing oxirane rings containing only hydrogen and carbon atoms in addition to the ring oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
HK07104000.3A 2003-11-07 2007-04-17 Processes for preparing bicyclo[3.1.0] hexane derivatives, and intermediates thereto HK1096971A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51839103P 2003-11-07 2003-11-07
PCT/US2004/036574 WO2005047215A2 (en) 2003-11-07 2004-11-03 Processes for preparing bicyclo [3.1.0] hexane derivatives, and intermediates thereto

Publications (1)

Publication Number Publication Date
HK1096971A1 true HK1096971A1 (en) 2007-06-15

Family

ID=34590258

Family Applications (2)

Application Number Title Priority Date Filing Date
HK07104000.3A HK1096971A1 (en) 2003-11-07 2007-04-17 Processes for preparing bicyclo[3.1.0] hexane derivatives, and intermediates thereto
HK10105009.6A HK1139124A1 (en) 2003-11-07 2010-05-24 Processes for preparing bicyclo [3.1.0] hexane derivatives, and intermediates thereto

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK10105009.6A HK1139124A1 (en) 2003-11-07 2010-05-24 Processes for preparing bicyclo [3.1.0] hexane derivatives, and intermediates thereto

Country Status (11)

Country Link
US (1) US7786314B2 (zh)
EP (1) EP1689727A4 (zh)
JP (1) JP4742239B2 (zh)
KR (1) KR101204145B1 (zh)
CN (2) CN100475800C (zh)
AU (1) AU2004289652B8 (zh)
CA (1) CA2544560C (zh)
HK (2) HK1096971A1 (zh)
RU (1) RU2388747C2 (zh)
TW (1) TWI347316B (zh)
WO (1) WO2005047215A2 (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5309680B2 (ja) * 2008-05-09 2013-10-09 大正製薬株式会社 フッ素化エステル化合物の製造方法及びその中間体
EP2679570A3 (en) 2008-05-21 2014-07-02 Taisho Pharmaceutical Co., Ltd. Method of producing bicyclo[3.1.0]hexane derivative
EP2502897B1 (en) * 2009-11-18 2014-07-09 Taisho Pharmaceutical Co., Ltd. Method for producing optically active bicyclo [3.1.0]hexane derivative using enzyme
IL277071B1 (en) 2018-03-08 2024-03-01 Incyte Corp Aminopyrizine diol compounds as PI3K–y inhibitors
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750566A (en) 1994-08-12 1998-05-12 Eli Lilly And Company Synthetic excitatory amino acids
ZA983930B (en) 1997-05-14 1999-11-08 Lilly Co Eli Excitatory amino acid receptor modulators.
ATE269293T1 (de) * 1998-08-31 2004-07-15 Taisho Pharmaceutical Co Ltd 6-fluoro(3.1.0)hexan-derivate
JP4194715B2 (ja) * 1998-08-31 2008-12-10 大正製薬株式会社 ６−フルオロビシクロ［３．１．０］ヘキサン誘導体
JP2000072731A (ja) * 1998-08-31 2000-03-07 Taisho Pharmaceut Co Ltd ４−置換−２−アミノビシクロ［３．１．０］ヘキサン−２，６−ジカルボン酸誘導体及び製薬用組成物
PE20001236A1 (es) 1998-11-13 2000-11-10 Lilly Co Eli Moduladores del receptor de aminoacidos excitadores
CN1134400C (zh) * 1999-03-25 2004-01-14 大正制药株式会社 新的羧酸衍生物及其制备方法
AU2001267855B2 (en) 2000-06-28 2005-09-08 Taisho Pharmaceutical Co., Ltd. Intermediate and process for producing fluorinated carboxylic acid derivative from the same
JP4124656B2 (ja) * 2001-03-14 2008-07-23 大正製薬株式会社 ビシクロカルボン酸誘導体の製造方法

Also Published As

Publication number Publication date
AU2004289652A1 (en) 2005-05-26
KR101204145B1 (ko) 2012-11-22
CA2544560C (en) 2014-01-07
EP1689727A4 (en) 2008-12-31
WO2005047215A2 (en) 2005-05-26
CN100475800C (zh) 2009-04-08
CN1898224A (zh) 2007-01-17
US20070112030A1 (en) 2007-05-17
RU2006119924A (ru) 2007-12-27
KR20060131771A (ko) 2006-12-20
HK1139124A1 (en) 2010-09-10
AU2004289652B8 (en) 2011-01-20
RU2388747C2 (ru) 2010-05-10
EP1689727A2 (en) 2006-08-16
JP2007513070A (ja) 2007-05-24
JP4742239B2 (ja) 2011-08-10
TW200530178A (en) 2005-09-16
AU2004289652B2 (en) 2010-09-16
CN101654410A (zh) 2010-02-24
CA2544560A1 (en) 2005-05-26
WO2005047215A3 (en) 2005-07-14
US7786314B2 (en) 2010-08-31
CN101654410B (zh) 2013-03-06
TWI347316B (en) 2011-08-21

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20141103