HK1096960A1 - Amidomethyl-substituted 2-(4-sulfonilamino)-3-hidroxy-3,4-dihydro-2h- chromium-6-yl-derivatives and drugs containing said compounds - Google Patents

Amidomethyl-substituted 2-(4-sulfonilamino)-3-hidroxy-3,4-dihydro-2h- chromium-6-yl-derivatives and drugs containing said compounds

Info

Publication number
HK1096960A1
HK1096960A1 HK07102051.5A HK07102051A HK1096960A1 HK 1096960 A1 HK1096960 A1 HK 1096960A1 HK 07102051 A HK07102051 A HK 07102051A HK 1096960 A1 HK1096960 A1 HK 1096960A1
Authority
HK
Hong Kong
Prior art keywords
sulfonilamino
hidroxy
amidomethyl
dihydro
chromium
Prior art date
Application number
HK07102051.5A
Other languages
English (en)
Inventor
D Sykes
B Moloney
L Marrison
D Ziegler
M Mlinaric
C Boecker
R Brueckner
M Weske
K Witte
Y Fischer
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of HK1096960A1 publication Critical patent/HK1096960A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK07102051.5A 2003-10-17 2007-02-23 Amidomethyl-substituted 2-(4-sulfonilamino)-3-hidroxy-3,4-dihydro-2h- chromium-6-yl-derivatives and drugs containing said compounds HK1096960A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10348298A DE10348298A1 (de) 2003-10-17 2003-10-17 Amidomethyl-substituierte 2-(4-Sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-ylderivade, Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
PCT/EP2004/052539 WO2005037780A2 (de) 2003-10-17 2004-10-14 Amidomethyl-substituierte 2-(4-sulfonilamino)-3-hidroxy-3,4-dihydro-2h-chromen-6-yl-derivate, verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
HK1096960A1 true HK1096960A1 (en) 2007-06-15

Family

ID=34442032

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07102051.5A HK1096960A1 (en) 2003-10-17 2007-02-23 Amidomethyl-substituted 2-(4-sulfonilamino)-3-hidroxy-3,4-dihydro-2h- chromium-6-yl-derivatives and drugs containing said compounds

Country Status (25)

Country Link
EP (1) EP1678130B1 (zh)
JP (1) JP4791968B2 (zh)
KR (1) KR20060129170A (zh)
CN (1) CN100532375C (zh)
AR (1) AR046106A1 (zh)
AT (1) ATE405547T1 (zh)
AU (1) AU2004281195B2 (zh)
BR (1) BRPI0415523A (zh)
CA (1) CA2542813C (zh)
DE (3) DE10348298A1 (zh)
DK (1) DK1678130T3 (zh)
ES (1) ES2313126T3 (zh)
HK (1) HK1096960A1 (zh)
HR (1) HRP20080602T3 (zh)
IL (1) IL174950A (zh)
MX (1) MXPA06003958A (zh)
NO (1) NO20062202L (zh)
PL (1) PL1678130T3 (zh)
PT (1) PT1678130E (zh)
RU (1) RU2355685C2 (zh)
SI (1) SI1678130T1 (zh)
TW (1) TWI321564B (zh)
UA (1) UA82907C2 (zh)
WO (1) WO2005037780A2 (zh)
ZA (1) ZA200602788B (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1871758B1 (en) * 2005-04-12 2010-08-25 Abbott Products GmbH Aminoalkyl-amidomethyl-substituted 2- (4-sulphonylamino) -3-hydroxy-3 , 4-dihydro-2h-cromen-6-yl derivatives and their use as potassium channel blockers
US7714150B2 (en) 2005-04-12 2010-05-11 Solvay Pharmaceuticals Gmbh Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chroman-6-yl derivatives
JP4943429B2 (ja) * 2005-07-22 2012-05-30 メルク・シャープ・エンド・ドーム・コーポレイション カリウムチャネル阻害剤
GB0525164D0 (en) 2005-12-09 2006-01-18 Xention Discovery Ltd Compounds
GB0815781D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB0815782D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB0815784D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
NO3175985T3 (zh) 2011-07-01 2018-04-28
JP2015504923A (ja) 2012-01-27 2015-02-16 ギリアード サイエンシーズ, インコーポレイテッド 後期ナトリウムイオンチャネル遮断剤およびカリウムイオンチャネル遮断剤を使用する併用療法
WO2014134419A1 (en) 2013-03-01 2014-09-04 Gilead Sciences, Inc. Use of ikach blockers for the treatment of cardiac diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ282172B6 (cs) * 1992-11-30 1997-05-14 Smithkline Beecham Plc Benzpyranové analogy pro léčení úzkosti, mánie, deprese nebo symptomů po přerušení podávání drog nebo léčiv, způsob přípravy těchto sloučenin, jejich použití a farmaceutický prostředek obsahující tyto sloučeniny
DE19546736A1 (de) * 1995-12-14 1997-06-19 Hoechst Ag Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate
WO2000012077A1 (en) * 1998-09-01 2000-03-09 Bristol-Myers Squibb Company Potassium channel inhibitors and method
WO2000058300A1 (fr) * 1999-03-25 2000-10-05 Nissan Chemical Industries, Ltd. Derives du chroman
JP2000336085A (ja) * 1999-03-25 2000-12-05 Nissan Chem Ind Ltd クロマン誘導体
AU781365B2 (en) * 1999-12-21 2005-05-19 Icagen, Inc. Potassium channel inhibitors

Also Published As

Publication number Publication date
CA2542813A1 (en) 2005-04-28
WO2005037780A2 (de) 2005-04-28
TW200523259A (en) 2005-07-16
HRP20080602T3 (en) 2008-12-31
RU2355685C2 (ru) 2009-05-20
PT1678130E (pt) 2008-10-08
CN100532375C (zh) 2009-08-26
DE502004007916D1 (de) 2008-10-02
DE112004001659D2 (de) 2006-08-10
NO20062202L (no) 2006-07-03
CN1894233A (zh) 2007-01-10
CA2542813C (en) 2011-08-30
EP1678130B1 (de) 2008-08-20
MXPA06003958A (es) 2006-07-05
ES2313126T3 (es) 2009-03-01
IL174950A (en) 2010-06-30
EP1678130A2 (de) 2006-07-12
IL174950A0 (en) 2006-08-20
AU2004281195A2 (en) 2005-04-28
PL1678130T3 (pl) 2009-01-30
JP4791968B2 (ja) 2011-10-12
DK1678130T3 (da) 2008-12-01
DE10348298A1 (de) 2005-05-19
BRPI0415523A (pt) 2006-12-26
JP2007516235A (ja) 2007-06-21
ZA200602788B (en) 2008-01-30
SI1678130T1 (sl) 2008-12-31
ATE405547T1 (de) 2008-09-15
UA82907C2 (en) 2008-05-26
KR20060129170A (ko) 2006-12-15
TWI321564B (en) 2010-03-11
AU2004281195A1 (en) 2005-04-28
AR046106A1 (es) 2005-11-23
AU2004281195B2 (en) 2010-12-16
RU2006116629A (ru) 2007-11-27
WO2005037780A3 (de) 2007-10-18

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20131014