IL174950A0 - Amidomethyl-subsituted 2-(4-sulfonilamino)-3-hydroxy-3,4-dihydro-2h-chromium-6-yl-derivatives and drugs containing said compounds - Google Patents

Amidomethyl-subsituted 2-(4-sulfonilamino)-3-hydroxy-3,4-dihydro-2h-chromium-6-yl-derivatives and drugs containing said compounds

Info

Publication number
IL174950A0
IL174950A0 IL174950A IL17495006A IL174950A0 IL 174950 A0 IL174950 A0 IL 174950A0 IL 174950 A IL174950 A IL 174950A IL 17495006 A IL17495006 A IL 17495006A IL 174950 A0 IL174950 A0 IL 174950A0
Authority
IL
Israel
Prior art keywords
sulfonilamino
amidomethyl
subsituted
dihydro
chromium
Prior art date
Application number
IL174950A
Other versions
IL174950A (en
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of IL174950A0 publication Critical patent/IL174950A0/en
Publication of IL174950A publication Critical patent/IL174950A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL174950A 2003-10-17 2006-04-11 Amidomethyl-subsituted 2 - (4 - sulfonilamino) - 3 - hydroxy - 3, 4 - dihydro -2h - chromen - 6 - yl -derivatives and drugs containing said compounds IL174950A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10348298A DE10348298A1 (en) 2003-10-17 2003-10-17 Amidomethyl-substituted 2- (4-sulfonylamino) -3-hydroxy-3,4-dihydro-2H-chromen-6-ylderivade, processes and intermediates for their preparation, and medicaments containing these compounds
PCT/EP2004/052539 WO2005037780A2 (en) 2003-10-17 2004-10-14 Amidomethyl-substituted 2-(4-sulfonilamino)-3-hidroxy-3,4-dihydro-2h-chromium-6-yl-derivatives and drugs containing said compounds

Publications (2)

Publication Number Publication Date
IL174950A0 true IL174950A0 (en) 2006-08-20
IL174950A IL174950A (en) 2010-06-30

Family

ID=34442032

Family Applications (1)

Application Number Title Priority Date Filing Date
IL174950A IL174950A (en) 2003-10-17 2006-04-11 Amidomethyl-subsituted 2 - (4 - sulfonilamino) - 3 - hydroxy - 3, 4 - dihydro -2h - chromen - 6 - yl -derivatives and drugs containing said compounds

Country Status (25)

Country Link
EP (1) EP1678130B1 (en)
JP (1) JP4791968B2 (en)
KR (1) KR20060129170A (en)
CN (1) CN100532375C (en)
AR (1) AR046106A1 (en)
AT (1) ATE405547T1 (en)
AU (1) AU2004281195B2 (en)
BR (1) BRPI0415523A (en)
CA (1) CA2542813C (en)
DE (3) DE10348298A1 (en)
DK (1) DK1678130T3 (en)
ES (1) ES2313126T3 (en)
HK (1) HK1096960A1 (en)
HR (1) HRP20080602T3 (en)
IL (1) IL174950A (en)
MX (1) MXPA06003958A (en)
NO (1) NO20062202L (en)
PL (1) PL1678130T3 (en)
PT (1) PT1678130E (en)
RU (1) RU2355685C2 (en)
SI (1) SI1678130T1 (en)
TW (1) TWI321564B (en)
UA (1) UA82907C2 (en)
WO (1) WO2005037780A2 (en)
ZA (1) ZA200602788B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1871758B1 (en) * 2005-04-12 2010-08-25 Abbott Products GmbH Aminoalkyl-amidomethyl-substituted 2- (4-sulphonylamino) -3-hydroxy-3 , 4-dihydro-2h-cromen-6-yl derivatives and their use as potassium channel blockers
US7714150B2 (en) 2005-04-12 2010-05-11 Solvay Pharmaceuticals Gmbh Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chroman-6-yl derivatives
JP4943429B2 (en) * 2005-07-22 2012-05-30 メルク・シャープ・エンド・ドーム・コーポレイション Potassium channel inhibitor
GB0525164D0 (en) 2005-12-09 2006-01-18 Xention Discovery Ltd Compounds
GB0815781D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB0815782D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
GB0815784D0 (en) 2008-08-29 2008-10-08 Xention Ltd Novel potassium channel blockers
NO3175985T3 (en) 2011-07-01 2018-04-28
JP2015504923A (en) 2012-01-27 2015-02-16 ギリアード サイエンシーズ, インコーポレイテッド Combination therapy using late sodium ion channel blockers and potassium ion channel blockers
WO2014134419A1 (en) 2013-03-01 2014-09-04 Gilead Sciences, Inc. Use of ikach blockers for the treatment of cardiac diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ282172B6 (en) * 1992-11-30 1997-05-14 Smithkline Beecham Plc Benzopyran analogs process for preparing such compounds, pharmaceutical composition containing such compounds and the use thereof
DE19546736A1 (en) * 1995-12-14 1997-06-19 Hoechst Ag Substituted chromanylsulfonyl (thio) ureas, process for their preparation and their use in the manufacture of pharmaceutical preparations
WO2000012077A1 (en) * 1998-09-01 2000-03-09 Bristol-Myers Squibb Company Potassium channel inhibitors and method
WO2000058300A1 (en) * 1999-03-25 2000-10-05 Nissan Chemical Industries, Ltd. Chroman derivatives
JP2000336085A (en) * 1999-03-25 2000-12-05 Nissan Chem Ind Ltd Chroman derivative
AU781365B2 (en) * 1999-12-21 2005-05-19 Icagen, Inc. Potassium channel inhibitors

Also Published As

Publication number Publication date
CA2542813A1 (en) 2005-04-28
WO2005037780A2 (en) 2005-04-28
TW200523259A (en) 2005-07-16
HRP20080602T3 (en) 2008-12-31
RU2355685C2 (en) 2009-05-20
PT1678130E (en) 2008-10-08
CN100532375C (en) 2009-08-26
DE502004007916D1 (en) 2008-10-02
DE112004001659D2 (en) 2006-08-10
NO20062202L (en) 2006-07-03
CN1894233A (en) 2007-01-10
CA2542813C (en) 2011-08-30
EP1678130B1 (en) 2008-08-20
MXPA06003958A (en) 2006-07-05
ES2313126T3 (en) 2009-03-01
IL174950A (en) 2010-06-30
EP1678130A2 (en) 2006-07-12
AU2004281195A2 (en) 2005-04-28
PL1678130T3 (en) 2009-01-30
JP4791968B2 (en) 2011-10-12
DK1678130T3 (en) 2008-12-01
DE10348298A1 (en) 2005-05-19
BRPI0415523A (en) 2006-12-26
JP2007516235A (en) 2007-06-21
ZA200602788B (en) 2008-01-30
HK1096960A1 (en) 2007-06-15
SI1678130T1 (en) 2008-12-31
ATE405547T1 (en) 2008-09-15
UA82907C2 (en) 2008-05-26
KR20060129170A (en) 2006-12-15
TWI321564B (en) 2010-03-11
AU2004281195A1 (en) 2005-04-28
AR046106A1 (en) 2005-11-23
AU2004281195B2 (en) 2010-12-16
RU2006116629A (en) 2007-11-27
WO2005037780A3 (en) 2007-10-18

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Legal Events

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FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees