HK1096660A1 - - Google Patents

Info

Publication number
HK1096660A1
HK1096660A1 HK07101193.6A HK07101193A HK1096660A1 HK 1096660 A1 HK1096660 A1 HK 1096660A1 HK 07101193 A HK07101193 A HK 07101193A HK 1096660 A1 HK1096660 A1 HK 1096660A1
Authority
HK
Hong Kong
Application number
HK07101193.6A
Inventor
Stephane Horvath
Marie-Noelle Auguste
Gerard Damien
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of HK1096660A1 publication Critical patent/HK1096660A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Medicinal Preparation (AREA)
HK07101193.6A 2005-02-28 2007-02-01 HK1096660A1 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0501990A FR2882556B1 (fr) 2005-02-28 2005-02-28 Forme cristalline gamma d du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent

Publications (1)

Publication Number Publication Date
HK1096660A1 true HK1096660A1 (da) 2007-06-08

Family

ID=34954879

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07101193.6A HK1096660A1 (da) 2005-02-28 2007-02-01

Country Status (43)

Country Link
US (3) US7361651B2 (da)
EP (1) EP1695709B1 (da)
JP (1) JP4628975B2 (da)
KR (1) KR100827503B1 (da)
CN (1) CN100432057C (da)
AP (1) AP2112A (da)
AR (1) AR056931A1 (da)
AT (1) ATE397933T1 (da)
AU (1) AU2006200855B2 (da)
BR (1) BRPI0600696A (da)
CA (1) CA2537404C (da)
CO (1) CO5770095A1 (da)
CR (1) CR8246A (da)
CU (1) CU23615B7 (da)
CY (1) CY1108220T1 (da)
DE (1) DE602006001411D1 (da)
DK (1) DK1695709T3 (da)
EA (1) EA008532B1 (da)
EC (1) ECSP066376A (da)
ES (1) ES2308688T3 (da)
FR (1) FR2882556B1 (da)
GE (1) GEP20084468B (da)
GT (1) GT200600086A (da)
HK (1) HK1096660A1 (da)
HR (1) HRP20080417T5 (da)
IL (1) IL173960A0 (da)
MA (1) MA28132A1 (da)
ME (2) ME01394B (da)
MY (1) MY157933A (da)
NO (1) NO338482B1 (da)
NZ (1) NZ545579A (da)
PE (1) PE20061070A1 (da)
PL (1) PL1695709T3 (da)
PT (1) PT1695709E (da)
RS (1) RS50600B (da)
SA (1) SA06270041B1 (da)
SG (1) SG125233A1 (da)
SI (1) SI1695709T1 (da)
TW (1) TWI314142B (da)
UA (1) UA81340C2 (da)
UY (1) UY29407A1 (da)
WO (1) WO2006092494A1 (da)
ZA (1) ZA200601760B (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2868777B1 (fr) * 2004-04-13 2006-05-26 Servier Lab Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
FR2882554B1 (fr) * 2005-02-28 2007-05-04 Servier Lab Forme critalline beta d du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2882556B1 (fr) * 2005-02-28 2007-05-04 Servier Lab Forme cristalline gamma d du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2882555B1 (fr) * 2005-02-28 2007-05-04 Servier Lab Forme cristalline gamma du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2882553B1 (fr) * 2005-02-28 2007-05-04 Servier Lab Forme cristalline beta du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2891826B1 (fr) * 2005-10-11 2007-12-28 Servier Lab Forme cristalline 6 du chlorhydrate de l'ivabradine, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2891827B1 (fr) * 2005-10-11 2007-12-28 Servier Lab Forme cristalline deltad du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2894825B1 (fr) * 2005-12-21 2010-12-03 Servier Lab Nouvelle association d'un inhibiteur du courant if sinusal et d'un inhibiteur de l'enzyme de conversion et les compositions pharmaceutiques qui la contiennent
ES2381771T3 (es) 2006-11-30 2012-05-31 Cadila Healthcare Limited Procedimiento para la preparación de hidrocloruro de ivabradina
CN101353325B (zh) * 2007-07-27 2011-11-09 上海优拓医药科技有限公司 稳定型盐酸伊伐布雷定结晶及其制备方法
EP2471780B1 (en) 2007-05-30 2014-11-26 Ind-Swift Laboratories Limited Crystalline Ivabradine Oxalate Salts and Polymorphs Thereof
ES2402765T3 (es) 2008-12-22 2013-05-08 Krka, D.D., Novo Mesto Procedimiento de preparación de ivabradina
CN101774969B (zh) 2009-01-13 2012-07-04 江苏恒瑞医药股份有限公司 硫酸伊伐布雷定及其i型结晶的制备方法
EA201290772A1 (ru) 2010-02-12 2013-02-28 КРКА, д.д., НОВО МЕСТО Новые формы ивабрадина гидрохлорида
HUP1000245A2 (en) 2010-05-07 2011-11-28 Richter Gedeon Nyrt Industrial process for the production ivabradin salts
WO2012025940A1 (en) 2010-08-25 2012-03-01 Cadila Healthcare Limited Polymorphic form of ivabradine hydrochloride and process for preparation thereof
US9440924B2 (en) 2011-08-02 2016-09-13 Sandoz Ag Acetone solvate of ivabradine hydrochloride
EP2773621B1 (en) 2011-11-04 2015-12-30 Synthon BV A process for making crystalline delta-form of ivabradine hydrochloride
EP2589594A1 (en) * 2011-11-04 2013-05-08 Urquima S.A. Ivabradine hydrochloride Form IV
EP2780327A1 (en) 2011-11-14 2014-09-24 Cadila Healthcare Limited Polymorphic forms of ivabradine hydrochloride
WO2014114341A1 (en) 2013-01-24 2014-07-31 Synthon Bv Process for making ivabradine
CZ305096B6 (cs) 2013-10-02 2015-04-29 Zentiva, K.S. Pevná forma Ivabradin hydrochloridu a (S)-mandlové kyseliny a její farmaceutická kompozice
WO2015001133A1 (en) 2013-12-12 2015-01-08 Synthon B.V. Pharmaceutical composition comprising amorphous ivabradine
ES2717715T3 (es) 2014-02-14 2019-06-24 Synthon Bv Composición farmacéutica que comprende polimorfo IV de clorhidrato de ivabradina
CZ2014478A3 (cs) 2014-07-10 2015-09-16 Zentiva, K.S. Pevná forma Ivabradin hydrochloridu a (R)-mandlové kyseliny a její farmaceutická kompozice
TWI598360B (zh) * 2016-12-19 2017-09-11 義守大學 Ｆｓｂｍ重組蛋白及其用途
EP3366282A1 (en) 2017-02-28 2018-08-29 Sanovel Ilac Sanayi ve Ticaret A.S. Solid oral pharmaceutical compositions of ivabradine
TR201703066A2 (tr) 2017-02-28 2018-09-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi İvabradi̇ni̇n kati oral farmasöti̇k kompozi̇syonlari
IT202000025312A1 (it) 2020-10-26 2022-04-26 Cambrex Profarmaco Milano S R L Processi per la preparazione di polimorfi di ivabradina hcl

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US534859A (en) * 1895-02-26 Condenser for ice-machines
DE3119874A1 (de) * 1981-05-19 1982-12-09 Dr. Karl Thomae Gmbh, 7950 Biberach "benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel"
DE3418270A1 (de) * 1984-05-17 1985-11-21 Dr. Karl Thomae Gmbh, 7950 Biberach Neue aminotetralinderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE69133158T2 (de) 1990-08-29 2003-07-17 Humanetics Corp Behandlungsverfahren zur förderung des gewichtsverlustes unter verwendung eines substituierten delta-5-androstens
FR2681862B1 (fr) * 1991-09-27 1993-11-12 Adir Cie Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent.
FR2818552B1 (fr) 2000-12-26 2003-02-07 Servier Lab Compositions pharmaceutique solide thermoformable pour la liberation controlee d'ivabradine
FR2868777B1 (fr) * 2004-04-13 2006-05-26 Servier Lab Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
FR2882553B1 (fr) * 2005-02-28 2007-05-04 Servier Lab Forme cristalline beta du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2882554B1 (fr) * 2005-02-28 2007-05-04 Servier Lab Forme critalline beta d du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2882555B1 (fr) * 2005-02-28 2007-05-04 Servier Lab Forme cristalline gamma du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2882556B1 (fr) * 2005-02-28 2007-05-04 Servier Lab Forme cristalline gamma d du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2891826B1 (fr) * 2005-10-11 2007-12-28 Servier Lab Forme cristalline 6 du chlorhydrate de l'ivabradine, son procede de preparation et les compositions pharmaceutiques qui la contiennent
FR2891827B1 (fr) * 2005-10-11 2007-12-28 Servier Lab Forme cristalline deltad du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent

Also Published As

Publication number Publication date
UY29407A1 (es) 2006-07-31
CO5770095A1 (es) 2007-06-29
MA28132A1 (fr) 2006-09-01
IL173960A0 (en) 2006-07-05
HRP20080417T5 (en) 2008-11-30
DE602006001411D1 (de) 2008-07-24
FR2882556A1 (fr) 2006-09-01
PL1695709T3 (pl) 2008-10-31
ME01394B (me) 2013-12-20
AU2006200855B2 (en) 2010-12-23
ME02750B (me) 2010-05-07
PT1695709E (pt) 2008-07-04
TW200640871A (en) 2006-12-01
CA2537404A1 (fr) 2006-08-28
EP1695709B1 (fr) 2008-06-11
GEP20084468B (en) 2008-08-25
US20090318420A1 (en) 2009-12-24
JP4628975B2 (ja) 2011-02-09
AP2112A (en) 2010-03-03
TWI314142B (en) 2009-09-01
US7872001B2 (en) 2011-01-18
EA200600323A1 (ru) 2006-08-25
WO2006092494A1 (fr) 2006-09-08
HRP20080417T3 (en) 2008-09-30
CN1827601A (zh) 2006-09-06
CA2537404C (fr) 2010-04-13
KR20060095503A (ko) 2006-08-31
SA06270041B1 (ar) 2010-03-08
PE20061070A1 (es) 2006-11-18
CN100432057C (zh) 2008-11-12
RS50600B (sr) 2010-05-07
CY1108220T1 (el) 2014-02-12
AP2006003522A0 (en) 2006-02-28
NO338482B1 (no) 2016-08-22
US7361651B2 (en) 2008-04-22
SG125233A1 (en) 2006-09-29
ATE397933T1 (de) 2008-07-15
BRPI0600696A (pt) 2007-05-08
NZ545579A (en) 2007-01-26
ZA200601760B (en) 2008-04-30
MY157933A (en) 2016-08-15
CR8246A (es) 2008-01-21
FR2882556B1 (fr) 2007-05-04
CU23615B7 (es) 2011-01-27
UA81340C2 (en) 2007-12-25
AR056931A1 (es) 2007-11-07
ES2308688T3 (es) 2008-12-01
ECSP066376A (es) 2006-11-16
GT200600086A (es) 2006-11-02
SI1695709T1 (sl) 2008-10-31
EP1695709A1 (fr) 2006-08-30
NO20060949L (no) 2006-08-29
US20080153804A1 (en) 2008-06-26
CU20060038A7 (es) 2008-06-30
DK1695709T3 (da) 2008-09-29
US20060194964A1 (en) 2006-08-31
EA008532B1 (ru) 2007-06-29
KR100827503B1 (ko) 2008-05-06
AU2006200855A1 (en) 2006-09-14
JP2006241157A (ja) 2006-09-14

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