HK1090065A1 - Preparation of somatostatin peptides - Google Patents

Preparation of somatostatin peptides

Info

Publication number
HK1090065A1
HK1090065A1 HK06110468A HK06110468A HK1090065A1 HK 1090065 A1 HK1090065 A1 HK 1090065A1 HK 06110468 A HK06110468 A HK 06110468A HK 06110468 A HK06110468 A HK 06110468A HK 1090065 A1 HK1090065 A1 HK 1090065A1
Authority
HK
Hong Kong
Prior art keywords
preparation
somatostatin peptides
somatostatin
peptides
Prior art date
Application number
HK06110468A
Other languages
English (en)
Inventor
Hellstern Heribert
Pachinger Werner
Parikoszovich Walter
Wietfeld Bernhard
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HK1090065A1 publication Critical patent/HK1090065A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • C07K14/6555Somatostatins at least 1 amino acid in D-form
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
HK06110468A 2003-08-08 2006-09-20 Preparation of somatostatin peptides HK1090065A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0318682.2A GB0318682D0 (en) 2003-08-08 2003-08-08 Organic compounds
PCT/EP2004/008850 WO2005014624A2 (en) 2003-08-08 2004-08-06 Preparation of somatostatin peptides

Publications (1)

Publication Number Publication Date
HK1090065A1 true HK1090065A1 (en) 2006-12-15

Family

ID=27839906

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06110468A HK1090065A1 (en) 2003-08-08 2006-09-20 Preparation of somatostatin peptides

Country Status (35)

Country Link
US (1) US7615609B2 (is)
EP (1) EP1654280B8 (is)
JP (1) JP4580928B2 (is)
KR (1) KR101136633B1 (is)
CN (2) CN1832962A (is)
AR (1) AR045327A1 (is)
AT (1) ATE394424T1 (is)
AU (1) AU2004262570B2 (is)
BR (1) BRPI0413437B1 (is)
CA (1) CA2534224C (is)
CO (1) CO5660271A2 (is)
CY (1) CY1108775T1 (is)
DE (1) DE602004013599D1 (is)
DK (1) DK1654280T3 (is)
EC (1) ECSP066352A (is)
ES (1) ES2307039T3 (is)
GB (1) GB0318682D0 (is)
HK (1) HK1090065A1 (is)
HR (1) HRP20080350T3 (is)
IL (1) IL173272A (is)
IS (1) IS2894B (is)
MA (1) MA27982A1 (is)
MX (1) MXPA06001525A (is)
MY (1) MY141731A (is)
NO (1) NO338367B1 (is)
NZ (1) NZ544961A (is)
PE (2) PE20050356A1 (is)
PL (1) PL1654280T3 (is)
PT (1) PT1654280E (is)
RU (1) RU2360921C2 (is)
SI (1) SI1654280T1 (is)
TN (1) TNSN06045A1 (is)
TW (1) TWI345570B (is)
WO (1) WO2005014624A2 (is)
ZA (1) ZA200600584B (is)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5331817B2 (ja) * 2007-12-03 2013-10-30 イタルファルマコ ソシエタ ペル アチオニ 新規な非選択的ソマトスタチン類似体
EP2067786A1 (en) 2007-12-07 2009-06-10 ITALFARMACO S.p.A. Novel non selective analogs of somatostatin
ES2522167T3 (es) 2010-01-05 2014-11-13 National Dong Hwa University Formulación anticancerosa
CN103467575B (zh) * 2013-08-22 2016-03-02 深圳翰宇药业股份有限公司 一种帕西瑞肽的制备方法
CN103641894B (zh) * 2013-12-06 2015-10-28 深圳翰宇药业股份有限公司 一种治疗库欣病的多肽药物的制备方法
EP3233899B1 (en) * 2014-12-19 2020-06-24 Auro Peptides LTD A process for the preparation of pasireotide
CN106188231B (zh) * 2015-05-25 2021-10-22 中国医学科学院药物研究所 帕西瑞肽五肽中间体的合成与应用
CN114621326B (zh) * 2020-12-10 2023-12-26 武汉武药科技有限公司 门冬氨酸帕瑞肽及其中间体和其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3303345A1 (de) * 1983-02-02 1984-08-02 Hoechst Ag, 6230 Frankfurt Cyclische peptide mit somatostatin-wirkung
EP0255224A3 (en) 1986-06-30 1990-04-18 Merck & Co. Inc. Cyclic and bridged cyclic somatostatin analogs useful as analgesic agents
US5811512A (en) 1991-08-22 1998-09-22 The Trustees Of The University Of Pennsylvania Non-peptide peptidomimetics and related cyclic hexapeptides
SG48977A1 (en) * 1993-06-23 1998-05-18 Diatide Inc Radiolabeled peptides
US5770687A (en) 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
US6355613B1 (en) 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
GB0018891D0 (en) * 2000-08-01 2000-09-20 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
CN1832962A (zh) 2006-09-13
CA2534224A1 (en) 2005-02-17
TNSN06045A1 (en) 2007-10-03
CN102127155B (zh) 2013-11-27
BRPI0413437A (pt) 2006-10-10
NZ544961A (en) 2008-08-29
PT1654280E (pt) 2008-08-18
RU2360921C2 (ru) 2009-07-10
KR20060070541A (ko) 2006-06-23
EP1654280A2 (en) 2006-05-10
MY141731A (en) 2010-06-15
CY1108775T1 (el) 2014-04-09
MXPA06001525A (es) 2006-05-15
US7615609B2 (en) 2009-11-10
AR045327A1 (es) 2005-10-26
PL1654280T3 (pl) 2008-10-31
PE20050356A1 (es) 2005-06-17
KR101136633B1 (ko) 2012-04-18
MA27982A1 (fr) 2006-07-03
WO2005014624A3 (en) 2005-09-22
IS2894B (is) 2014-09-15
TW200524955A (en) 2005-08-01
ATE394424T1 (de) 2008-05-15
DK1654280T3 (da) 2008-09-29
SI1654280T1 (sl) 2008-10-31
NO20061125L (no) 2006-05-08
CO5660271A2 (es) 2006-07-31
AU2004262570A1 (en) 2005-02-17
IL173272A (en) 2012-03-29
IL173272A0 (en) 2006-06-11
ZA200600584B (en) 2006-12-27
ES2307039T3 (es) 2008-11-16
CN102127155A (zh) 2011-07-20
BRPI0413437B1 (pt) 2017-12-12
AU2004262570B2 (en) 2008-06-19
JP2007526899A (ja) 2007-09-20
HRP20080350T3 (en) 2008-08-31
WO2005014624A2 (en) 2005-02-17
EP1654280B8 (en) 2008-08-13
EP1654280B1 (en) 2008-05-07
GB0318682D0 (en) 2003-09-10
RU2006106721A (ru) 2007-09-20
DE602004013599D1 (de) 2008-06-19
JP4580928B2 (ja) 2010-11-17
IS8338A (is) 2006-03-02
US20060258838A1 (en) 2006-11-16
TWI345570B (en) 2011-07-21
NO338367B1 (no) 2016-08-15
ECSP066352A (es) 2006-08-30
CA2534224C (en) 2012-03-27
PE20091210A1 (es) 2009-09-07

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Legal Events

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PE Patent expired

Effective date: 20240801