HK1080836A1 - Isoquinoline derivatives - Google Patents

Isoquinoline derivatives

Info

Publication number
HK1080836A1
HK1080836A1 HK06100541A HK06100541A HK1080836A1 HK 1080836 A1 HK1080836 A1 HK 1080836A1 HK 06100541 A HK06100541 A HK 06100541A HK 06100541 A HK06100541 A HK 06100541A HK 1080836 A1 HK1080836 A1 HK 1080836A1
Authority
HK
Hong Kong
Prior art keywords
isoquinoline derivatives
isoquinoline
derivatives
Prior art date
Application number
HK06100541A
Other languages
English (en)
Inventor
Andrea Cesura
Rosa Maria Rodriguez Sarmiento
Michelangelo Scalone
Andrew William Thomas
Rene Wyler
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1080836A1 publication Critical patent/HK1080836A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
HK06100541A 2002-04-26 2006-01-13 Isoquinoline derivatives HK1080836A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02009253 2002-04-26
PCT/EP2003/003845 WO2003091219A1 (en) 2002-04-26 2003-04-14 Isoquinoline derivatives

Publications (1)

Publication Number Publication Date
HK1080836A1 true HK1080836A1 (en) 2006-05-04

Family

ID=29265896

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06100541A HK1080836A1 (en) 2002-04-26 2006-01-13 Isoquinoline derivatives

Country Status (31)

Country Link
US (1) US6818774B2 (xx)
EP (1) EP1501804B1 (xx)
JP (1) JP4322685B2 (xx)
KR (1) KR100681585B1 (xx)
CN (1) CN1310890C (xx)
AR (1) AR039651A1 (xx)
AT (1) ATE440821T1 (xx)
AU (1) AU2003227614B2 (xx)
BR (1) BR0309562A (xx)
CA (1) CA2483461C (xx)
DE (1) DE60328978D1 (xx)
DK (1) DK1501804T3 (xx)
ES (1) ES2329354T3 (xx)
GT (1) GT200300095A (xx)
HK (1) HK1080836A1 (xx)
HR (1) HRP20040952A2 (xx)
IL (1) IL164677A0 (xx)
MX (1) MXPA04010537A (xx)
MY (1) MY133527A (xx)
NO (1) NO20044571L (xx)
NZ (1) NZ535885A (xx)
PA (1) PA8572001A1 (xx)
PE (1) PE20040594A1 (xx)
PL (1) PL373697A1 (xx)
PT (1) PT1501804E (xx)
RU (1) RU2318812C2 (xx)
SI (1) SI1501804T1 (xx)
TW (1) TWI278451B (xx)
UY (1) UY27786A1 (xx)
WO (1) WO2003091219A1 (xx)
ZA (1) ZA200408281B (xx)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY150088A (en) 2003-05-19 2013-11-29 Irm Llc Immunosuppressant compounds and compositions
JP4728962B2 (ja) * 2003-05-19 2011-07-20 アイアールエム・リミテッド・ライアビリティ・カンパニー 免疫抑制化合物および組成物
EP1638551B1 (en) * 2003-05-19 2011-12-21 Irm Llc Immunosuppressant compounds and compositions
MXPA06002310A (es) 2003-08-29 2006-05-25 Ono Pharmaceutical Co Compuesto capaz de enlazarse al receptor s1p y uso farmaceutico del mismo.
CN101407471A (zh) 2003-08-29 2009-04-15 小野药品工业株式会社 能够结合s1p受体的化合物及其药物用途
CA2543287A1 (en) * 2003-10-23 2005-05-06 F.Hoffmann-La Roche Ag Benzazepine derivatives as mao-b inhibitors
SI1751111T1 (sl) 2004-03-01 2015-04-30 Actelion Pharmaceuticals Ltd. Substituirani 1,2,3,4-tetrahidroizokinolinski derivati
PL1826197T3 (pl) 2004-12-13 2012-06-29 Ono Pharmaceutical Co Pochodna kwasu aminokarboksylowego i jej zastosowanie lecznicze
CA2595339C (en) * 2005-01-28 2014-08-19 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for producing isochromane and derivatives thereof
UA90708C2 (ru) 2005-02-25 2010-05-25 Ф. Хоффманн-Ля Рош Аг Таблетки с улучшенной дисперсностью лекарственного вещества
NZ567540A (en) 2005-12-22 2010-07-30 Newron Pharm Spa 2-Phenylethylamino derivatives as calcium and/or sodium channel modulators
MX2008011647A (es) * 2006-03-15 2008-09-22 Actelion Pharmaceuticals Ltd Derivados de tetrahidroisoquinolina para mejorar la funcion de la memoria.
WO2007122591A2 (en) 2006-04-26 2007-11-01 Actelion Pharmaceuticals Ltd Pyrazolo-tetrahydro pyridine derivatives as orexin receptor antagonists
KR101220182B1 (ko) 2009-02-25 2013-01-11 에스케이바이오팜 주식회사 치환된 아졸 유도체 화합물, 이를 포함하는 약제학적 조성물 및 이를 이용한 파킨슨씨 병 치료방법
CN105315204B (zh) * 2014-07-04 2018-02-09 中南大学 7‑氨基‑1,4‑二氢异喹啉‑3(2h)‑酮衍生物及其合成方法和用途
CN105585527B (zh) * 2015-12-17 2018-06-26 浙江工业大学 2-(3,4-二氢异喹啉-1(2h)-亚基)乙腈类化合物及其应用
CN105461626B (zh) * 2015-12-17 2018-05-08 浙江工业大学 芳环或稠杂环联3,4-二氢异喹啉类共轭结构化合物及其应用
WO2018183171A1 (en) * 2017-03-27 2018-10-04 Bristol-Myers Squibb Company Substituted isoquionline derivatives as immunomudulators
CN114591238B (zh) * 2022-03-25 2022-11-15 邦恩泰(山东)生物医药科技集团股份有限公司 一种异喹啉类药物中间体的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6448269B1 (en) * 1993-07-22 2002-09-10 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists
US5731324A (en) * 1993-07-22 1998-03-24 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists
US6137002A (en) * 1993-07-22 2000-10-24 Eli Lilly And Company Glycoprotein IIb/IIIa antagonists
IL110172A (en) * 1993-07-22 2001-10-31 Lilly Co Eli Bicycle compounds and pharmaceuticals containing them
US5679715A (en) 1995-06-07 1997-10-21 Harris; Richard Y. Method for treating multiple sclerosis
WO1997033572A1 (en) 1996-03-15 1997-09-18 Somerset Pharmaceuticals, Inc. Method for preventing and treating peripheral neurophathy by administering selegiline
WO2001034172A2 (en) 1999-11-05 2001-05-17 Vela Pharmaceuticals Inc. Methods and compositions for treating reward deficiency syndrome

Also Published As

Publication number Publication date
RU2004134575A (ru) 2005-07-20
AU2003227614B2 (en) 2008-06-26
NZ535885A (en) 2007-05-31
US6818774B2 (en) 2004-11-16
AR039651A1 (es) 2005-03-02
BR0309562A (pt) 2005-02-15
HRP20040952A2 (en) 2005-06-30
DE60328978D1 (de) 2009-10-08
CA2483461A1 (en) 2003-11-06
WO2003091219A1 (en) 2003-11-06
CN1649844A (zh) 2005-08-03
US20030225122A1 (en) 2003-12-04
JP4322685B2 (ja) 2009-09-02
PA8572001A1 (es) 2003-12-10
TW200307670A (en) 2003-12-16
JP2005533761A (ja) 2005-11-10
PL373697A1 (en) 2005-09-05
MY133527A (en) 2007-11-30
RU2318812C2 (ru) 2008-03-10
KR100681585B1 (ko) 2007-02-09
SI1501804T1 (sl) 2009-12-31
ZA200408281B (en) 2005-10-14
IL164677A0 (en) 2005-12-18
EP1501804B1 (en) 2009-08-26
TWI278451B (en) 2007-04-11
UY27786A1 (es) 2003-10-31
CA2483461C (en) 2010-12-21
KR20040104628A (ko) 2004-12-10
MXPA04010537A (es) 2005-01-25
PE20040594A1 (es) 2004-08-30
ATE440821T1 (de) 2009-09-15
PT1501804E (pt) 2009-10-29
NO20044571L (no) 2004-10-22
DK1501804T3 (da) 2009-10-12
AU2003227614A1 (en) 2003-11-10
CN1310890C (zh) 2007-04-18
ES2329354T3 (es) 2009-11-25
GT200300095A (es) 2004-01-15
EP1501804A1 (en) 2005-02-02

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20110414