HK1075044A1 - Crystalline polymorphic form of irinotecan hydrochloride - Google Patents
Crystalline polymorphic form of irinotecan hydrochlorideInfo
- Publication number
- HK1075044A1 HK1075044A1 HK05107303A HK05107303A HK1075044A1 HK 1075044 A1 HK1075044 A1 HK 1075044A1 HK 05107303 A HK05107303 A HK 05107303A HK 05107303 A HK05107303 A HK 05107303A HK 1075044 A1 HK1075044 A1 HK 1075044A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- polymorphic form
- irinotecan hydrochloride
- crystalline polymorphic
- crystalline
- irinotecan
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36068402P | 2002-03-01 | 2002-03-01 | |
| PCT/EP2003/001948 WO2003074527A1 (en) | 2002-03-01 | 2003-02-26 | Crystalline polymorphic form of irinotecan hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1075044A1 true HK1075044A1 (en) | 2005-12-02 |
Family
ID=27789001
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK05107303A HK1075044A1 (en) | 2002-03-01 | 2005-08-22 | Crystalline polymorphic form of irinotecan hydrochloride |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1487840B1 (ru) |
| JP (1) | JP2005525367A (ru) |
| KR (1) | KR20040091083A (ru) |
| CN (1) | CN1276923C (ru) |
| AR (1) | AR038618A1 (ru) |
| AT (1) | ATE364610T1 (ru) |
| AU (1) | AU2003215594A1 (ru) |
| BR (1) | BR0308133A (ru) |
| CA (1) | CA2477926A1 (ru) |
| DE (1) | DE60314378T2 (ru) |
| DK (1) | DK1487840T3 (ru) |
| ES (1) | ES2287495T3 (ru) |
| HK (1) | HK1075044A1 (ru) |
| IL (1) | IL163820A0 (ru) |
| MX (1) | MXPA04008484A (ru) |
| NO (1) | NO20044138L (ru) |
| NZ (1) | NZ534999A (ru) |
| PE (1) | PE20030923A1 (ru) |
| PL (1) | PL372318A1 (ru) |
| PT (1) | PT1487840E (ru) |
| RU (1) | RU2300535C2 (ru) |
| TW (1) | TWI270374B (ru) |
| WO (1) | WO2003074527A1 (ru) |
| ZA (1) | ZA200406927B (ru) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ541990A (en) * | 2003-02-25 | 2009-04-30 | Yakult Honsha Kk | Method for preparing polymorphism of irinotecan hydrochloride |
| ES2245891B1 (es) * | 2004-07-09 | 2006-11-16 | Clinmet S.L. | "metodo para la obtencion de un excipiente universal para la administracion oral de principios activos farmaceuticos y composiciones de excipientes resultantes del metodo". |
| CA2590756C (en) * | 2004-12-21 | 2014-09-02 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Stereoselective process and crystalline forms of a camptothecin |
| US7910737B2 (en) | 2005-02-07 | 2011-03-22 | Fermion Oy | Process for the manufacturing of 7-ethyl-10-hydroxy camptothecin |
| ES2430375T3 (es) | 2005-02-08 | 2013-11-20 | Fermion Oy | Procedimiento para la producción de cloruro de [1,4']bipiperidinil-1'-carbonilo o su clorhidrato |
| PL1928883T3 (pl) | 2005-02-08 | 2014-03-31 | Fermion Oy | Sposób otrzymywania chlorowodorku irynotekanu |
| US7435818B2 (en) * | 2005-09-20 | 2008-10-14 | Scinopharm Taiwan, Ltd. | Crystal forms of irinotecan hydrochloride |
| CN101318964B (zh) * | 2007-06-07 | 2010-12-15 | 上海迪赛诺医药发展有限公司 | 盐酸伊立替康新晶型及其制备方法 |
| FR2918279B1 (fr) * | 2007-07-05 | 2010-10-22 | Aventis Pharma Sa | Combinaisons antitumorales contenant un agent inhibiteur de vegf et de l'irinotecan |
| IT1391757B1 (it) * | 2008-11-11 | 2012-01-27 | Antibioticos Spa | Irinotecan cloridrato cristallino e metodi per la sua preparazione |
| CN101659667B (zh) * | 2009-09-07 | 2011-11-02 | 重庆泰濠制药有限公司 | 一种盐酸伊立替康的纯化方法 |
| US8546573B2 (en) | 2009-11-18 | 2013-10-01 | Cadila Healthcare Limited | Process for the preparation of 7-ethyl-10-[4-(1-piperidino)-1-piperdino] carbonyloxy-camptothecin hydrochloride trihydrate |
| JO3283B1 (ar) | 2011-04-26 | 2018-09-16 | Sanofi Sa | تركيب يتضمن أفليبيرسيبت, حمض فولينيك, 5- فلورويوراسيل (5- Fu) وإرينوسيتان (FOLFIRI) |
| CN102866126B (zh) * | 2011-07-05 | 2016-03-23 | 重庆华邦制药有限公司 | 一种定量测定化合物中晶型比例的方法 |
| CN102311443B (zh) * | 2011-08-24 | 2014-07-16 | 上海北卡医药技术有限公司 | 盐酸伊立替康的新晶型及其制备方法 |
| RU2529831C2 (ru) * | 2012-11-30 | 2014-09-27 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Российский университет дружбы народов" (РУДН) | Способ лечения рака толстой кишки |
| LT3170005T (lt) | 2014-07-18 | 2019-07-10 | Sanofi | Paciento, įtariamo, kad serga vėžiu, gydymo afliberceptu rezultato prognozavimo būdas |
| KR102293907B1 (ko) * | 2015-06-30 | 2021-08-26 | 한미약품 주식회사 | 이리노테칸 함유 경구용 고형제제 및 그 제조방법 |
| KR102066402B1 (ko) * | 2017-12-22 | 2020-01-15 | 대화제약 주식회사 | 이리노테칸 또는 그의 약제학적으로 허용가능한 염을 포함하는 경구투여용 약제학적 조성물 |
| US10919905B2 (en) * | 2019-05-16 | 2021-02-16 | Scinopharm Taiwan, Ltd. | Polymorphism for irinotecan free base |
-
2003
- 2003-02-26 MX MXPA04008484A patent/MXPA04008484A/es not_active Application Discontinuation
- 2003-02-26 EP EP03743335A patent/EP1487840B1/en not_active Expired - Lifetime
- 2003-02-26 BR BR0308133-8A patent/BR0308133A/pt not_active IP Right Cessation
- 2003-02-26 DE DE60314378T patent/DE60314378T2/de not_active Expired - Fee Related
- 2003-02-26 DK DK03743335T patent/DK1487840T3/da active
- 2003-02-26 CN CNB038072726A patent/CN1276923C/zh not_active Expired - Fee Related
- 2003-02-26 WO PCT/EP2003/001948 patent/WO2003074527A1/en active IP Right Grant
- 2003-02-26 NZ NZ534999A patent/NZ534999A/en unknown
- 2003-02-26 IL IL16382003A patent/IL163820A0/xx unknown
- 2003-02-26 AU AU2003215594A patent/AU2003215594A1/en not_active Abandoned
- 2003-02-26 KR KR10-2004-7013621A patent/KR20040091083A/ko not_active Application Discontinuation
- 2003-02-26 RU RU2004129307/04A patent/RU2300535C2/ru not_active IP Right Cessation
- 2003-02-26 PL PL03372318A patent/PL372318A1/xx not_active Application Discontinuation
- 2003-02-26 JP JP2003572995A patent/JP2005525367A/ja not_active Withdrawn
- 2003-02-26 PT PT03743335T patent/PT1487840E/pt unknown
- 2003-02-26 ES ES03743335T patent/ES2287495T3/es not_active Expired - Lifetime
- 2003-02-26 AT AT03743335T patent/ATE364610T1/de not_active IP Right Cessation
- 2003-02-26 CA CA002477926A patent/CA2477926A1/en not_active Abandoned
- 2003-02-27 TW TW092104194A patent/TWI270374B/zh not_active IP Right Cessation
- 2003-02-28 AR ARP030100656A patent/AR038618A1/es unknown
- 2003-02-28 PE PE2003000196A patent/PE20030923A1/es not_active Application Discontinuation
-
2004
- 2004-08-31 ZA ZA200406927A patent/ZA200406927B/en unknown
- 2004-09-29 NO NO20044138A patent/NO20044138L/no not_active Application Discontinuation
-
2005
- 2005-08-22 HK HK05107303A patent/HK1075044A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2477926A1 (en) | 2003-09-12 |
| KR20040091083A (ko) | 2004-10-27 |
| PE20030923A1 (es) | 2003-10-29 |
| ZA200406927B (en) | 2006-06-28 |
| TWI270374B (en) | 2007-01-11 |
| TW200303753A (en) | 2003-09-16 |
| CN1276923C (zh) | 2006-09-27 |
| PT1487840E (pt) | 2007-09-11 |
| DE60314378T2 (de) | 2008-02-28 |
| NO20044138L (no) | 2004-11-29 |
| JP2005525367A (ja) | 2005-08-25 |
| AU2003215594A1 (en) | 2003-09-16 |
| NZ534999A (en) | 2007-03-30 |
| RU2300535C2 (ru) | 2007-06-10 |
| EP1487840A1 (en) | 2004-12-22 |
| DE60314378D1 (en) | 2007-07-26 |
| WO2003074527A1 (en) | 2003-09-12 |
| CN1642958A (zh) | 2005-07-20 |
| EP1487840B1 (en) | 2007-06-13 |
| RU2004129307A (ru) | 2005-04-10 |
| IL163820A0 (en) | 2005-12-18 |
| PL372318A1 (en) | 2005-07-11 |
| ATE364610T1 (de) | 2007-07-15 |
| DK1487840T3 (da) | 2007-07-16 |
| BR0308133A (pt) | 2005-01-04 |
| MXPA04008484A (es) | 2004-12-06 |
| ES2287495T3 (es) | 2007-12-16 |
| AR038618A1 (es) | 2005-01-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20110226 |