PL1928883T3 - Sposób otrzymywania chlorowodorku irynotekanu - Google Patents
Sposób otrzymywania chlorowodorku irynotekanuInfo
- Publication number
- PL1928883T3 PL1928883T3 PL06708892T PL06708892T PL1928883T3 PL 1928883 T3 PL1928883 T3 PL 1928883T3 PL 06708892 T PL06708892 T PL 06708892T PL 06708892 T PL06708892 T PL 06708892T PL 1928883 T3 PL1928883 T3 PL 1928883T3
- Authority
- PL
- Poland
- Prior art keywords
- preparation
- irinotecan hydrochloride
- irinotecan
- hydrochloride
- Prior art date
Links
- 229960000779 irinotecan hydrochloride Drugs 0.000 title 1
- GURKHSYORGJETM-WAQYZQTGSA-N irinotecan hydrochloride (anhydrous) Chemical compound Cl.C1=C2C(CC)=C3CN(C(C4=C([C@@](C(=O)OC4)(O)CC)C=4)=O)C=4C3=NC2=CC=C1OC(=O)N(CC1)CCC1N1CCCCC1 GURKHSYORGJETM-WAQYZQTGSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65052305P | 2005-02-08 | 2005-02-08 | |
| PCT/FI2006/000033 WO2006084941A2 (en) | 2005-02-08 | 2006-02-06 | Process for the preparation of irinotecan hydrochloride |
| EP06708892.2A EP1928883B1 (en) | 2005-02-08 | 2006-02-06 | Process for the preparation of irinotecan hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1928883T3 true PL1928883T3 (pl) | 2014-03-31 |
Family
ID=36593037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL06708892T PL1928883T3 (pl) | 2005-02-08 | 2006-02-06 | Sposób otrzymywania chlorowodorku irynotekanu |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7767813B2 (pl) |
| EP (1) | EP1928883B1 (pl) |
| JP (1) | JP5133704B2 (pl) |
| CA (1) | CA2591074C (pl) |
| ES (1) | ES2437573T3 (pl) |
| PL (1) | PL1928883T3 (pl) |
| WO (1) | WO2006084941A2 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007035709A2 (en) * | 2005-09-20 | 2007-03-29 | Scinopharm Singapore Pte, Ltd. | Novel crystal forms of irinotecan hydrochloride |
| US8546573B2 (en) | 2009-11-18 | 2013-10-01 | Cadila Healthcare Limited | Process for the preparation of 7-ethyl-10-[4-(1-piperidino)-1-piperdino] carbonyloxy-camptothecin hydrochloride trihydrate |
| CN102643283A (zh) * | 2012-05-08 | 2012-08-22 | 江苏红豆杉生物科技有限公司 | 一种制备盐酸伊立替康三水合物纯品的方法 |
| KR101327720B1 (ko) * | 2013-02-15 | 2013-11-11 | 제일약품주식회사 | 이리노테칸의 제조방법 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4473692A (en) | 1981-09-04 | 1984-09-25 | Kabushiki Kaisha Yakult Honsha | Camptothecin derivatives and process for preparing same |
| JPS6019790A (ja) * | 1983-07-14 | 1985-01-31 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| US4747692A (en) * | 1986-02-04 | 1988-05-31 | Harrison Roger D | Beverage dispenser |
| US5053512A (en) | 1987-04-14 | 1991-10-01 | Research Triangle Institute | Total synthesis of 20(S) and 20(R)-camptothecin and compthothecin derivatives |
| US4894456A (en) | 1987-03-31 | 1990-01-16 | Research Triangle Institute | Synthesis of camptothecin and analogs thereof |
| TW438775B (en) | 1995-04-07 | 2001-06-07 | Pharmacia & Upjohn Co Llc | Novel intermediates and process for the manufacture of camptothecin derivatives (CPT-11) and related compounds |
| SK1732001A3 (en) * | 1998-08-05 | 2001-06-11 | Aventis Pharma Sa | Use of camptothecin derivatives, with reduced gastrointestinal toxicity |
| AR035684A1 (es) | 2001-02-21 | 2004-06-23 | Yakult Honsha Kk | Procedimiento para preparar 2'-amino-5'-hidroxipropiofenona, uso de la misma para la preparacion de analogos de camptotecina, procedimiento para prepararlos, compuestos intermediarios, procedimiento para preparar una cetona triciclica utilizada en la sintesis de analogos de camptotecina |
| DE60314378T2 (de) | 2002-03-01 | 2008-02-28 | Pfizer Italia S.R.L. | Kristalline polymorphe form von irinotecanhydrochlorid |
| BR0309284A (pt) * | 2002-04-17 | 2005-02-22 | Pharmacia Corp | Compostos úteis na preparação de derivados de camptotecina |
| US20050267141A1 (en) | 2004-05-28 | 2005-12-01 | Phytogen Life Sciences Inc. | Process to prepare camptothecin derivatives |
| WO2006016203A1 (en) * | 2004-08-09 | 2006-02-16 | Shilpa Medicare Limited | An improved process for the preparation of irinotecan hydrochloride trihydrate |
| EP1846412B1 (en) * | 2005-02-07 | 2009-10-21 | Fermion Oy | Process for the manufacturing of 7-ethyl-10-hydroxy camptothecin |
-
2006
- 2006-02-06 JP JP2007553633A patent/JP5133704B2/ja not_active Expired - Fee Related
- 2006-02-06 US US11/883,581 patent/US7767813B2/en not_active Expired - Fee Related
- 2006-02-06 WO PCT/FI2006/000033 patent/WO2006084941A2/en not_active Ceased
- 2006-02-06 ES ES06708892.2T patent/ES2437573T3/es active Active
- 2006-02-06 PL PL06708892T patent/PL1928883T3/pl unknown
- 2006-02-06 CA CA2591074A patent/CA2591074C/en not_active Expired - Fee Related
- 2006-02-06 EP EP06708892.2A patent/EP1928883B1/en not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| EP1928883B1 (en) | 2013-10-30 |
| ES2437573T3 (es) | 2014-01-13 |
| US20080161572A1 (en) | 2008-07-03 |
| JP2008529992A (ja) | 2008-08-07 |
| US7767813B2 (en) | 2010-08-03 |
| CA2591074A1 (en) | 2006-08-17 |
| CA2591074C (en) | 2015-01-20 |
| EP1928883A2 (en) | 2008-06-11 |
| WO2006084941A2 (en) | 2006-08-17 |
| WO2006084941A3 (en) | 2007-01-25 |
| JP5133704B2 (ja) | 2013-01-30 |
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