HK1067642A1 - Novel galactosylceramide analogs and beta-glucocerebrosidase activators, external skin preparations and method of activating beta-glucocerebrosidase using the analogs - Google Patents

Novel galactosylceramide analogs and beta-glucocerebrosidase activators, external skin preparations and method of activating beta-glucocerebrosidase using the analogs

Info

Publication number
HK1067642A1
HK1067642A1 HK05100756A HK05100756A HK1067642A1 HK 1067642 A1 HK1067642 A1 HK 1067642A1 HK 05100756 A HK05100756 A HK 05100756A HK 05100756 A HK05100756 A HK 05100756A HK 1067642 A1 HK1067642 A1 HK 1067642A1
Authority
HK
Hong Kong
Prior art keywords
glucocerebrosidase
analogs
beta
novel
activators
Prior art date
Application number
HK05100756A
Other languages
English (en)
Inventor
Rie Uematsu
Fumio Nakajima
Masahiro Yoshida
Kyoko Fukunaga
Mariko Hara
Shintaro Inoue
Shinichiro Nishimura
Original Assignee
Kao Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kao Corp filed Critical Kao Corp
Publication of HK1067642A1 publication Critical patent/HK1067642A1/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cosmetics (AREA)
HK05100756A 2001-06-28 2005-01-28 Novel galactosylceramide analogs and beta-glucocerebrosidase activators, external skin preparations and method of activating beta-glucocerebrosidase using the analogs HK1067642A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001196016A JP4070966B2 (ja) 2001-06-28 2001-06-28 新規ガラクトシルセラミド類縁体及び用途
PCT/JP2002/006532 WO2003002584A1 (fr) 2001-06-28 2002-06-27 Nouveaux analogues de galactosylceramide et activateurs de $g(b)-glucocerebrosidase, preparations externes pour la peau et procede d'activation de $g(b)-glucocerebrosidase au moyen d'analogues

Publications (1)

Publication Number Publication Date
HK1067642A1 true HK1067642A1 (en) 2005-04-15

Family

ID=19033898

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05100756A HK1067642A1 (en) 2001-06-28 2005-01-28 Novel galactosylceramide analogs and beta-glucocerebrosidase activators, external skin preparations and method of activating beta-glucocerebrosidase using the analogs

Country Status (9)

Country Link
US (2) US7183261B2 (zh)
EP (1) EP1408045B1 (zh)
JP (1) JP4070966B2 (zh)
KR (1) KR100739250B1 (zh)
CN (1) CN1247605C (zh)
DE (1) DE60232449D1 (zh)
HK (1) HK1067642A1 (zh)
TW (2) TWI322151B (zh)
WO (1) WO2003002584A1 (zh)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101936685B1 (ko) * 2011-11-16 2019-01-11 (주)아모레퍼시픽 글리코실 세라마이드 유사 화합물, 이의 제조방법 및 이를 함유하는 화장료 조성물
JP5918168B2 (ja) * 2012-04-27 2016-05-18 富士フイルム株式会社 β−グルコセレブロシダーゼ活性増強剤
WO2014053482A1 (en) 2012-10-03 2014-04-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the prophylactic treatment of bacterial superinfections post-influenza with invariant nkt cell agonists
KR101589633B1 (ko) * 2014-09-18 2016-02-01 한국과학기술연구원 당세라마이드 유도체 및 이의 제조방법
EP3215509B1 (en) 2014-11-06 2020-02-26 Lysosomal Therapeutics Inc. Substituted pyrrolo[1,2-a]pyrimidines and their use in the treatment of medical disorders
EP4406616A3 (en) 2014-11-06 2024-11-06 Bial-R&D Investments, S.A. Substituted pyrazolo(1,5-a)pyrimidines and their use in the treatment of medical disorders
WO2016073889A1 (en) 2014-11-06 2016-05-12 Lysosomal Therapeutics Inc. Substituted imidazo[1,5-a]pyrimidines and their use in the treatment of medical disorders
WO2017027848A1 (en) * 2015-08-12 2017-02-16 The Arizona Board Of Regents On Behalf Of The University Of Arizona Glycosylated peptides with pseudoproline residues and having enhanced half-lives and ability to cross the blood brain barrier
US10709758B2 (en) 2015-09-03 2020-07-14 The Board Of Regents Of The University Of Oklahoma Peptide inhibitors of clostridium difficile toxin B (TcdB) toxin
JP7034935B2 (ja) 2016-04-06 2022-03-14 リソソーマル・セラピューティクス・インコーポレイテッド ピロロ［１，２－ａ］ピリミジニルカルボキサミド化合物および医学的障害の処置におけるその使用
KR20230104752A (ko) 2016-04-06 2023-07-10 비알 - 알&디 인베스트먼츠, 에스.에이. 피라졸로[1,5-a]피리미디닐 카르복스아미드 화합물및 의학적 장애의 치료에서의 그의 용도
JP7046827B2 (ja) 2016-04-06 2022-04-04 リソソーマル・セラピューティクス・インコーポレイテッド イミダゾ［１，５－ａ］ピリミジニルカルボキサミド化合物および医学的障害の処置におけるその使用
EP3452455A4 (en) 2016-05-05 2019-11-13 Lysosomal Therapeutics Inc. SUBSTITUTED IMDAZO [1,2-] PYRIDINES, SUBSTITUTED IMIDAZO [1,2-] PYRAZINES, RELATED COMPOUNDS AND THEIR USE IN THE TREATMENT OF ILLNESSES
WO2017192930A1 (en) 2016-05-05 2017-11-09 Lysosomal Therapeutics Inc. SUBSTITUTED IMIDAZO[1,2-b]PYRIDAZINES, SUBSTITUTED IMIDAZO[1,5-b]PYRIDAZINES, RELATED COMPOUNDS, AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS
WO2017207040A1 (en) 2016-06-01 2017-12-07 Vib Vzw ANTI-CANCER THERAPY USING A LEPTIN ANTAGONIST AND AN iNKT-CELL ACTIVATOR
US10933126B2 (en) 2018-05-03 2021-03-02 The Board Of Regents Of The University Of Oklahoma Clostridium difficile immunogenic compositions and methods of use
FR3147951A1 (fr) * 2023-04-19 2024-10-25 Paris Sciences Et Lettres Particules de monosaccharides modifies par une chaine hydrophobe et de cyclodextrine.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07110872B2 (ja) * 1990-09-25 1995-11-29 株式会社ディ・ディ・エス研究所 酸性糖脂質及び微粒子キャリヤー
JP2774417B2 (ja) 1991-08-07 1998-07-09 株式会社ディ・ディ・エス研究所 ペプチド骨格を有する分枝鎖型糖複合体及び微粒子キャリヤー
IT1271624B (it) 1994-03-21 1997-06-04 Lifegroup Spa Derivati glucosidici di n-acil alchilamine capaci di esercitare effetto o neuroprotettivo utilizzabili nelle patologie acute e croniche del sistema nervoso centrale correlate ad eccitotossicita'
JP2896321B2 (ja) * 1994-10-27 1999-05-31 鐘紡株式会社 β−グルコセレブロシダーゼの活性化方法

Also Published As

Publication number Publication date
EP1408045A4 (en) 2005-12-28
EP1408045A1 (en) 2004-04-14
CN1247605C (zh) 2006-03-29
DE60232449D1 (de) 2009-07-09
CN1522263A (zh) 2004-08-18
JP2003012684A (ja) 2003-01-15
EP1408045B1 (en) 2009-05-27
KR100739250B1 (ko) 2007-07-12
US20070111951A1 (en) 2007-05-17
TW201002734A (en) 2010-01-16
KR20040048381A (ko) 2004-06-09
WO2003002584A1 (fr) 2003-01-09
US20040242499A1 (en) 2004-12-02
TWI322151B (zh) 2010-03-21
JP4070966B2 (ja) 2008-04-02
US7183261B2 (en) 2007-02-27

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Legal Events

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PE Patent expired

Effective date: 20220626