HK1058043A1 - Process for the production of 16,17-[(cyclohexylmethylen)bis(oxy)]-11,21- dihydroxy-pregna-1,4-dien-3,20-dion or its 21-isobutyrat by transketalisation ; - Google Patents

Process for the production of 16,17-[(cyclohexylmethylen)bis(oxy)]-11,21- dihydroxy-pregna-1,4-dien-3,20-dion or its 21-isobutyrat by transketalisation ;

Info

Publication number
HK1058043A1
HK1058043A1 HK04100855.0A HK04100855A HK1058043A1 HK 1058043 A1 HK1058043 A1 HK 1058043A1 HK 04100855 A HK04100855 A HK 04100855A HK 1058043 A1 HK1058043 A1 HK 1058043A1
Authority
HK
Hong Kong
Prior art keywords
oxy
bis
cyclohexylmethylen
isobutyrat
transketalisation
Prior art date
Application number
HK04100855.0A
Other languages
English (en)
Inventor
Beate Schmidt
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Publication of HK1058043A1 publication Critical patent/HK1058043A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Liquid Crystal Substances (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HK04100855.0A 2000-11-10 2004-02-09 Process for the production of 16,17-[(cyclohexylmethylen)bis(oxy)]-11,21- dihydroxy-pregna-1,4-dien-3,20-dion or its 21-isobutyrat by transketalisation ; HK1058043A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00124626 2000-11-10
PCT/EP2001/012808 WO2002038584A1 (en) 2000-11-10 2001-11-06 Process for the production of 16,17-[(cyclohexylmethylen)bis(oxy)]-11,21-dihydroxy-pregna-1,4-dien-3,20-dion or its 21-isobutyrat by transketalisation

Publications (1)

Publication Number Publication Date
HK1058043A1 true HK1058043A1 (en) 2004-04-30

Family

ID=8170345

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04100855.0A HK1058043A1 (en) 2000-11-10 2004-02-09 Process for the production of 16,17-[(cyclohexylmethylen)bis(oxy)]-11,21- dihydroxy-pregna-1,4-dien-3,20-dion or its 21-isobutyrat by transketalisation ;

Country Status (23)

Country Link
US (1) US7468433B2 (xx)
EP (1) EP1335929B1 (xx)
JP (1) JP4456811B2 (xx)
KR (2) KR100809510B1 (xx)
CN (1) CN1264855C (xx)
AT (1) ATE478888T1 (xx)
AU (1) AU2953602A (xx)
BR (1) BR0115220A (xx)
CA (1) CA2430196C (xx)
CZ (1) CZ303885B6 (xx)
DE (1) DE60142920D1 (xx)
EA (1) EA006231B1 (xx)
ES (1) ES2351184T3 (xx)
HK (1) HK1058043A1 (xx)
HU (1) HU228432B1 (xx)
IL (1) IL155274A0 (xx)
MX (1) MXPA03004123A (xx)
NO (1) NO325286B1 (xx)
NZ (1) NZ525707A (xx)
PL (1) PL205674B1 (xx)
SK (1) SK287545B6 (xx)
WO (1) WO2002038584A1 (xx)
ZA (1) ZA200303121B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100404545C (zh) * 2003-03-27 2008-07-23 尼科梅德有限责任公司 具有规定粒径的结晶环缩松的制备方法
MY143936A (en) * 2003-03-27 2011-07-29 Nycomed Gmbh Process for preparing crystalline ciclesonide with defined particle size
CN100338089C (zh) * 2004-08-12 2007-09-19 重庆医药工业研究院有限责任公司 一种哮喘病治疗药物环索奈德的新的制备方法
CN100345864C (zh) * 2004-10-29 2007-10-31 天津药业研究院有限公司 一种治疗呼吸道疾病的甾体药物的制备方法及其中间体
WO2007054974A2 (en) * 2005-09-28 2007-05-18 Arch Pharmalab Limited A green chemistry process for the preparation of pregnadiene esters
WO2008015696A2 (en) * 2006-05-23 2008-02-07 Cadila Healthcare Limited Process for preparing ciclesonide
JP2010503722A (ja) 2006-09-19 2010-02-04 シプラ・リミテッド シクレソニドとその結晶変異体の調製方法
US9109005B2 (en) 2012-02-23 2015-08-18 Boehringer Ingelheim International Gmbh Method for manufacturing of ciclesonide
US10233210B2 (en) 2015-01-30 2019-03-19 Coral Drugs Pvt. Ltd. Process for preparation of glucocorticoid steroids
KR20220119529A (ko) 2016-06-02 2022-08-29 애브비 인코포레이티드 글루코코르티코이드 수용체 작용제 및 이의 면역접합체
ES2877659T3 (es) 2017-12-01 2021-11-17 Abbvie Inc Agonista del receptor de glucocorticoides y sus inmunoconjugados

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880368A (en) * 1983-10-24 1989-11-14 Siegfried C. Hasl In-mold label transfer apparatus
ES8506753A1 (es) 1983-11-24 1985-08-01 Frumtost Zyma S A Procedimiento para la obtencion de un corticoide de accion antipsoriatica
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
SE8604059D0 (sv) * 1986-09-25 1986-09-25 Astra Pharma Prod A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives
GR1001529B (el) 1990-09-07 1994-03-31 Elmuquimica Farm Sl Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης.
FR2675146A1 (fr) 1991-04-10 1992-10-16 Roussel Uclaf Nouveaux derives sterouides de la pregna-1,4-diene-3,20-dione, leur preparation, leur application a la preparation de derives 16,17-methylene dioxy substitues et nouveaux intermediaires.
US5733901A (en) * 1993-04-02 1998-03-31 Byk Gulden Lomberg Chemische Fabrik Gmbh Prednisolone derivatives
DE19635498A1 (de) 1996-09-03 1998-03-26 Byk Gulden Lomberg Chem Fab Verfahren zur Epimerenanreicherung

Also Published As

Publication number Publication date
IL155274A0 (en) 2003-11-23
CZ303885B6 (cs) 2013-06-12
JP4456811B2 (ja) 2010-04-28
US7468433B2 (en) 2008-12-23
ES2351184T3 (es) 2011-02-01
HUP0302220A3 (en) 2007-11-28
ATE478888T1 (de) 2010-09-15
CA2430196A1 (en) 2002-05-16
CN1264855C (zh) 2006-07-19
EP1335929B1 (en) 2010-08-25
NO20031964L (no) 2003-04-30
KR20070116185A (ko) 2007-12-06
WO2002038584A1 (en) 2002-05-16
SK287545B6 (sk) 2011-01-04
HUP0302220A2 (hu) 2003-10-28
PL205674B1 (pl) 2010-05-31
HU228432B1 (hu) 2013-03-28
EP1335929A1 (en) 2003-08-20
NZ525707A (en) 2004-11-26
NO325286B1 (no) 2008-03-17
SK5552003A3 (en) 2003-08-05
DE60142920D1 (de) 2010-10-07
AU2953602A (en) 2002-05-21
CA2430196C (en) 2010-01-26
NO20031964D0 (no) 2003-04-30
US20050080063A1 (en) 2005-04-14
KR20030081329A (ko) 2003-10-17
CN1473164A (zh) 2004-02-04
KR100809510B1 (ko) 2008-03-04
EA200300504A1 (ru) 2003-12-25
MXPA03004123A (es) 2004-09-10
EA006231B1 (ru) 2005-10-27
JP2004513181A (ja) 2004-04-30
PL361616A1 (en) 2004-10-04
ZA200303121B (en) 2004-04-23
BR0115220A (pt) 2003-10-07

Similar Documents

Publication Publication Date Title
EP0164636A3 (en) A process for the preparation of 16,17 acetals of pregnane derivatives and compounds obtained therefrom
HK1058043A1 (en) Process for the production of 16,17-[(cyclohexylmethylen)bis(oxy)]-11,21- dihydroxy-pregna-1,4-dien-3,20-dion or its 21-isobutyrat by transketalisation ;
BG96166A (bg) Метод за получаване на будезонид
EE03927B1 (et) Meetod R-epimeeri suhtelise sisalduse suurendamiseks [11B,16a(R/S)]-16,17-[(tsükloheksüülmetüleen)bis(oksü)]-11-hüdroksü-21-(2-metüül-1-oksopropoksü)pregna-1,4-dieen-3,20-diooni R/S-epimeerses segus ja selle segu valmistamismeetod
GR910100353A (en) Process for the obtainment of a new pregna-1,4-diene-3,20-dione -16-17-acetal-21 esters
WO1998043936A3 (en) Improved methods of manufacturing betulinic acid
WO2001051451A3 (en) Methods for manufacturing betulinic acid
WO2002026759A3 (de) 17α-FLUORALKYLSTEROIDE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE VERBINDUNGEN ENTHALTENDE PHARMAZEUTISCHE ZUSAMMENSETZUNGEN
AU567934B2 (en) Preparation 21-hydroxy-20-keto-delta 16 steroids and intermediates
PL358032A1 (en) New application of 22r-(11, 16)-16,17-[butylidene-bis-oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione
ATE277071T1 (de) Durch 11-beta-aryl-17,17-spirothiolan substituierte steroide
MXPA03005372A (es) Androgenos 14 (15) -insaturados, 15- y/o 16-sustituidos, con perfil de actividad mixto androgenico-progestacional.
MXPA03011751A (es) Proceso para preparar 21-acetato de 11b,17a, 21-trihidroxi-6a-metilpregna-1, 4-dieno-3, 20- diona.
WO2004033478A3 (en) Fatty acid modified forms of glucocorticoids and their use as anti-inflammatory
MXPA04002758A (es) Transacetalizacion estereoselectiva de acetonido c-22 esteroidal.
WO2004074305A3 (en) Process for the production of 2-oxa-3-one androstane derivatives
GR3033940T3 (en) PREPARATION OF (11-g(b),16-g(b))-21-(3-CARBOXY-3-OXOPROPOXY)-11-HYDROXY-2'-METHYL-5'H-PREGNA-1,4-DIENO 17,16-D]OXAZOLE-3,20-DIONE
NO941919L (no) Fremgangsmåte for fremstilling av steroide peracylglycosider
AU2503099A (en) Method for producing a factor viii/von willebrand factor complex
JPS54148770A (en) Steroid derivative

Legal Events

Date Code Title Description
CHRG Changes in the register

Free format text: CORRECTION OF THE NAME OF THE INVENTOR FROM BEATE GUTTERER TO BEATE SCHMIDT

PE Patent expired

Effective date: 20211105