HK1056681A1 - Gabapentin analogues for sleep disorders - Google Patents

Gabapentin analogues for sleep disorders

Info

Publication number
HK1056681A1
HK1056681A1 HK03109027A HK03109027A HK1056681A1 HK 1056681 A1 HK1056681 A1 HK 1056681A1 HK 03109027 A HK03109027 A HK 03109027A HK 03109027 A HK03109027 A HK 03109027A HK 1056681 A1 HK1056681 A1 HK 1056681A1
Authority
HK
Hong Kong
Prior art keywords
sleep disorders
gabapentin analogues
gabapentin
analogues
compounds
Prior art date
Application number
HK03109027A
Other languages
English (en)
Inventor
Justin Stephen Bryans
Leonard Theodore Meltzer
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of HK1056681A1 publication Critical patent/HK1056681A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK03109027A 2000-06-26 2003-12-11 Gabapentin analogues for sleep disorders HK1056681A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21417100P 2000-06-26 2000-06-26
PCT/US2001/016343 WO2002000209A2 (en) 2000-06-26 2001-05-18 Gabapentin analogues for sleep disorders

Publications (1)

Publication Number Publication Date
HK1056681A1 true HK1056681A1 (en) 2004-02-27

Family

ID=22798045

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03109027A HK1056681A1 (en) 2000-06-26 2003-12-11 Gabapentin analogues for sleep disorders

Country Status (24)

Country Link
US (1) US7141606B2 (zh)
EP (1) EP1296671B1 (zh)
JP (1) JP3909842B2 (zh)
KR (1) KR100785182B1 (zh)
CN (1) CN1279900C (zh)
AT (1) ATE390133T1 (zh)
AU (2) AU2001264736B2 (zh)
BR (1) BR0111913A (zh)
CA (1) CA2414008C (zh)
CZ (1) CZ20024110A3 (zh)
DE (1) DE60133389T2 (zh)
DK (1) DK1296671T3 (zh)
ES (1) ES2300332T3 (zh)
HK (1) HK1056681A1 (zh)
HU (1) HUP0300833A3 (zh)
IL (2) IL152770A0 (zh)
MX (1) MXPA02010668A (zh)
NZ (1) NZ522480A (zh)
PL (1) PL359872A1 (zh)
PT (1) PT1296671E (zh)
SK (1) SK17922002A3 (zh)
TW (1) TWI298020B (zh)
WO (1) WO2002000209A2 (zh)
ZA (1) ZA200209418B (zh)

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TNSN03094A1 (fr) 2001-04-19 2005-12-23 Warner Lambert Co Amino-acides condenses bicycliques ou tricycliques
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
WO2002100344A2 (en) 2001-06-11 2002-12-19 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
MXPA03011565A (es) 2001-06-11 2004-10-28 Xenoport Inc Profarmacos de analogos de gaba, composiciones y usos de las mismas.
EP1485082A4 (en) 2002-02-19 2009-12-30 Xenoport Inc PROCESS FOR THE SYNTHESIS OF PROMEDICAMENTS FROM 1-ACYL-ALKYL DERIVATIVES AND CORRESPONDING COMPOSITIONS
WO2003080588A1 (en) 2002-03-20 2003-10-02 Xenoport Cyclic 1-(acyloxy)-alkyl prodrugs of gaba analogs, compositions and uses thereof
WO2003099338A2 (en) 2002-05-17 2003-12-04 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
AU2003297927A1 (en) 2002-12-11 2004-06-30 Xenoport, Inc. Prodrugs of fused gaba analogs, pharmaceutical compositions and uses thereof
EP1572184A1 (en) * 2002-12-13 2005-09-14 Warner-Lambert Company Gabapentin analogues for fibromyalgia and other related disorders
CA2451267A1 (en) * 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
WO2004093827A2 (en) * 2003-03-25 2004-11-04 Kiel Laboratories, Inc. Phenolic acid salts of gabapentin in solid dosage forms and methods of use
EP1670451A4 (en) 2003-09-11 2009-10-21 Xenoport Inc TREATMENT AND / OR PREVENTION OF URINARY INCONTINENCE AND PROMOTERS OF GABA ANALOGS
WO2005027850A2 (en) 2003-09-17 2005-03-31 Xenoport, Inc. Treating or preventing restless legs syndrome using prodrugs of gaba analogs
JP4308263B2 (ja) 2003-10-14 2009-08-05 ゼノポート，インコーポレイティド γ−アミノ酪酸アナログの結晶形
JP4613031B2 (ja) * 2004-05-06 2011-01-12 エスエス製薬株式会社 催眠剤組成物
JP2005325070A (ja) * 2004-05-14 2005-11-24 Ss Pharmaceut Co Ltd 睡眠改善剤
JP2008518971A (ja) 2004-11-04 2008-06-05 ゼノポート，インコーポレイティド ガバペンチンプロドラッグ持続放出経口薬剤
CA2612186A1 (en) 2005-06-23 2007-01-04 Emory University Imaging agents
KR20070070307A (ko) * 2005-08-24 2007-07-04 에스에스 세야쿠 가부시키 가이샤 수면 개선 의약 조성물
WO2007102058A1 (en) * 2006-03-06 2007-09-13 Pfizer Products Inc. Alpha-2-delta ligands for non-restorative sleep
EP2250148B1 (en) 2008-01-25 2016-08-17 XenoPort, Inc. Crystalline form of calcium-salts of (3s)-aminomethyl-5-methyl-hexanoic acids and methods of use
US8062870B2 (en) 2008-01-25 2011-11-22 Xenoport, Inc. Enantiomerically resolving acyloxyalkyl thiocarbonates used in synthesizing acyloxyalkyl carbamate prodrugs
US7868043B2 (en) 2008-01-25 2011-01-11 Xenoport, Inc. Mesophasic forms of (3S)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
CN102216257B (zh) 2008-10-08 2015-11-25 凯飞药业公司 Gaba偶联物及其使用方法
CA2783699C (en) 2009-12-08 2019-01-15 Case Western Reserve University Primary amine compounds for treating ocular disorders
US9066853B2 (en) 2013-01-15 2015-06-30 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable fiber
EP2948139B1 (en) 2013-01-28 2019-06-12 Lopez, Hector, L. Methods of improving tolerability, pharmacodynamics, and efficacy of b-alanine and use therefor
JP7381000B2 (ja) * 2016-05-26 2023-11-15 株式会社アミノアップ 睡眠改善剤
JP7441181B2 (ja) 2018-05-14 2024-02-29 エックスジーン ファーマシューティカル インク． ナプロキセンとプレガバリンの１－（アシルオキシ）－アルキルカルバメート薬品複合体の結晶形態

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US4087544A (en) 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
DE2460891C2 (de) 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US5084479A (en) 1990-01-02 1992-01-28 Warner-Lambert Company Novel methods for treating neurodegenerative diseases
US6197819B1 (en) 1990-11-27 2001-03-06 Northwestern University Gamma amino butyric acid analogs and optical isomers
US5510381A (en) 1995-05-15 1996-04-23 Warner-Lambert Company Method of treatment of mania and bipolar disorder
DE19525598C2 (de) * 1995-07-13 1997-09-25 Max Planck Gesellschaft Schlafmittel
EA001214B1 (ru) * 1996-03-14 2000-12-25 Варнер-Ламберт Компани Новые мостиковые циклические аминокислоты как фармацевтически применимые вещества
US6372792B1 (en) * 1996-04-26 2002-04-16 Guy Chouinard Method for treating anxiety, anxiety disorders and insomnia
DK1032555T3 (da) * 1997-10-27 2006-07-17 Warner Lambert Co Cykliske aminosyrer og derivater deraf, som er anvendelige som lægemidler
US6306910B1 (en) * 1998-07-09 2001-10-23 Warner-Lambert Company Use of Gaba-analogues for treating insomnia
ES2185591T3 (es) * 1999-06-02 2003-05-01 Warner Lambert Co Amino hererociclos utiles como agentes farmaceuticos.
HN2000000224A (es) * 1999-10-20 2001-04-11 Warner Lambert Co Aminoacidos biciclicos como agentes farmaceuticos
EP1237847B1 (en) * 1999-12-08 2006-05-17 Warner-Lambert Company Llc Method for the stereoselective synthesis of cyclic amino acids
GB9930083D0 (en) * 1999-12-20 2000-02-09 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
CN1436075A (zh) 2003-08-13
IL152770A0 (en) 2003-06-24
EP1296671A2 (en) 2003-04-02
HUP0300833A2 (hu) 2003-08-28
DE60133389T2 (de) 2008-06-26
US7141606B2 (en) 2006-11-28
CZ20024110A3 (cs) 2003-10-15
ATE390133T1 (de) 2008-04-15
NZ522480A (en) 2005-06-24
WO2002000209A2 (en) 2002-01-03
DK1296671T3 (da) 2008-06-16
US20030212133A1 (en) 2003-11-13
MXPA02010668A (es) 2003-03-10
TWI298020B (en) 2008-06-21
ZA200209418B (en) 2005-03-10
AU2001264736B2 (en) 2006-04-27
JP2004501189A (ja) 2004-01-15
KR100785182B1 (ko) 2007-12-11
JP3909842B2 (ja) 2007-04-25
BR0111913A (pt) 2004-01-06
DE60133389D1 (de) 2008-05-08
CN1279900C (zh) 2006-10-18
SK17922002A3 (sk) 2003-11-04
AU6473601A (en) 2002-01-08
CA2414008C (en) 2011-04-26
ES2300332T3 (es) 2008-06-16
KR20030019455A (ko) 2003-03-06
CA2414008A1 (en) 2002-01-03
WO2002000209A3 (en) 2003-01-16
PL359872A1 (en) 2004-09-06
IL152770A (en) 2009-12-24
HUP0300833A3 (en) 2009-08-28
PT1296671E (pt) 2008-05-09
EP1296671B1 (en) 2008-03-26

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130518