HK1051533A1 - Substituted 1,3-diaryl-2-pyridine-2-yl-3-(pyridine-2-ylamino)-propanol derivatives, methods for their production, pharmaceutical compositions containing the same and their use. - Google Patents
Substituted 1,3-diaryl-2-pyridine-2-yl-3-(pyridine-2-ylamino)-propanol derivatives, methods for their production, pharmaceutical compositions containing the same and their use.Info
- Publication number
- HK1051533A1 HK1051533A1 HK03103726A HK03103726A HK1051533A1 HK 1051533 A1 HK1051533 A1 HK 1051533A1 HK 03103726 A HK03103726 A HK 03103726A HK 03103726 A HK03103726 A HK 03103726A HK 1051533 A1 HK1051533 A1 HK 1051533A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pyridine
- ylamino
- diaryl
- substituted
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19845406A DE19845406C2 (de) | 1998-10-02 | 1998-10-02 | Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
PCT/EP1999/006933 WO2000020393A1 (fr) | 1998-10-02 | 1999-09-18 | Derives de 1,3-diaryl-2-pyridine-2-yl-3-(pyridine-2-ylamino)propanol substitues, procedes permettant de les preparer, medicaments contenant lesdits composes et leur utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1051533A1 true HK1051533A1 (en) | 2003-08-08 |
Family
ID=7883187
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK03103726A HK1051533A1 (en) | 1998-10-02 | 2003-05-27 | Substituted 1,3-diaryl-2-pyridine-2-yl-3-(pyridine-2-ylamino)-propanol derivatives, methods for their production, pharmaceutical compositions containing the same and their use. |
Country Status (23)
Country | Link |
---|---|
US (1) | US6596728B1 (fr) |
EP (1) | EP1117642B1 (fr) |
JP (1) | JP4544746B2 (fr) |
KR (1) | KR100609255B1 (fr) |
CN (1) | CN1173951C (fr) |
AR (1) | AR021845A1 (fr) |
AT (1) | ATE267809T1 (fr) |
AU (1) | AU757689B2 (fr) |
BR (1) | BR9915027B1 (fr) |
CA (1) | CA2345985C (fr) |
CZ (1) | CZ299569B6 (fr) |
DE (2) | DE19845406C2 (fr) |
DK (1) | DK1117642T3 (fr) |
ES (1) | ES2219066T3 (fr) |
HK (1) | HK1051533A1 (fr) |
HU (1) | HU226688B1 (fr) |
ID (1) | ID29249A (fr) |
PL (1) | PL205034B1 (fr) |
PT (1) | PT1117642E (fr) |
RU (1) | RU2224748C2 (fr) |
TR (1) | TR200100896T2 (fr) |
WO (1) | WO2000020393A1 (fr) |
ZA (1) | ZA200102587B (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030063462A (ko) | 2000-12-21 | 2003-07-28 | 아벤티스 파마 도이칠란트 게엠베하 | 디페닐 아제티디논 유도체, 이의 제조 방법, 이들화합물을 함유하는 약제 및 이의 용도 |
CN1638801A (zh) * | 2001-08-22 | 2005-07-13 | 安万特医药德国有限公司 | 芳基取代的丙醇胺衍生物与其他活性成分的联用产品及其应用 |
DE10219987A1 (de) * | 2002-05-03 | 2004-04-08 | Aventis Pharma Deutschland Gmbh | Optisch aktive β-Aminoketone, optisch aktive 1,3-Aminoalkohole und Verfahren zu deren Herstellung |
US7161008B2 (en) * | 2002-05-03 | 2007-01-09 | Sanofi - Aventis Deutschland GmbH | Optically active β-aminoketones, optically active 1,3-amino alcohols and processes for preparing them |
GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
AU2004283751B2 (en) * | 2003-10-24 | 2011-05-19 | Exelixis, Inc. | p70S6 kinase modulators and method of use |
WO2011150286A2 (fr) | 2010-05-26 | 2011-12-01 | Satiogen Pharmaceuticals,Inc. | Inhibiteurs et satiogènes de recyclage d'acide biliaire pour traitement du diabète, de l'obésité et d'états inflammatoires gastro-intestinaux |
CA2852957C (fr) | 2011-10-28 | 2020-08-04 | Lumena Pharmaceuticals, Inc. | Inhibiteurs du recyclage de l'acide biliaire pour traitement de l'hypercholemie et de la maladie cholestatique hepatique |
CA2853285C (fr) | 2011-10-28 | 2020-05-05 | Lumena Pharmaceuticals, Inc. | Inhibiteurs du recyclage de l'acide biliaire pour traitement de maladies cholestatiques hepatiques pediatriques |
KR20160002773A (ko) | 2013-03-15 | 2016-01-08 | 루메나 파마수티컬즈, 인코포레이티드 | 원발성 담관염 및 염증성 장 질환 치료용 담즙산 재순환 억제제 |
RU2015139732A (ru) | 2013-03-15 | 2017-04-24 | ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи | Ингибиторы рециркуляции желчных кислот для лечения пищевода барретта и гастроэзофагеальной рефлюксной болезни |
JP6361168B2 (ja) * | 2013-06-17 | 2018-07-25 | Jsr株式会社 | 液晶配向剤、液晶配向膜、液晶表示素子、液晶表示素子の製造方法、重合体及び化合物 |
WO2020167964A1 (fr) | 2019-02-12 | 2020-08-20 | Mirum Pharmaceuticals, Inc. | Réponse dépendant du génotype et de la dose à un asbti chez des patients ayant une déficience de pompe d'exportation de sel biliaire |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0000816A1 (fr) * | 1977-08-06 | 1979-02-21 | Beecham Group Plc | Dérivés substitués d'aminopyridines, leurs procédés de préparation et compositions pharmaceutiques les contenant |
PT869121E (pt) * | 1997-04-04 | 2004-10-29 | Aventis Pharma Gmbh | Derivados de propanolamina hipolipidemicos |
DE19845402B4 (de) * | 1998-10-02 | 2005-04-07 | Aventis Pharma Deutschland Gmbh | Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
DE19845405C2 (de) * | 1998-10-02 | 2000-07-13 | Aventis Pharma Gmbh | Arylsubstituierte Propanolaminderivate und deren Verwendung |
-
1998
- 1998-10-02 DE DE19845406A patent/DE19845406C2/de not_active Expired - Fee Related
-
1999
- 1999-09-18 PL PL347096A patent/PL205034B1/pl unknown
- 1999-09-18 AT AT99948791T patent/ATE267809T1/de active
- 1999-09-18 EP EP99948791A patent/EP1117642B1/fr not_active Expired - Lifetime
- 1999-09-18 BR BRPI9915027-1A patent/BR9915027B1/pt not_active IP Right Cessation
- 1999-09-18 TR TR2001/00896T patent/TR200100896T2/xx unknown
- 1999-09-18 PT PT99948791T patent/PT1117642E/pt unknown
- 1999-09-18 WO PCT/EP1999/006933 patent/WO2000020393A1/fr active IP Right Grant
- 1999-09-18 ID IDW20010736A patent/ID29249A/id unknown
- 1999-09-18 CA CA2345985A patent/CA2345985C/fr not_active Expired - Fee Related
- 1999-09-18 KR KR1020017004096A patent/KR100609255B1/ko not_active IP Right Cessation
- 1999-09-18 ES ES99948791T patent/ES2219066T3/es not_active Expired - Lifetime
- 1999-09-18 DE DE59909606T patent/DE59909606D1/de not_active Expired - Lifetime
- 1999-09-18 CZ CZ20011152A patent/CZ299569B6/cs not_active IP Right Cessation
- 1999-09-18 DK DK99948791T patent/DK1117642T3/da active
- 1999-09-18 JP JP2000574510A patent/JP4544746B2/ja not_active Expired - Fee Related
- 1999-09-18 HU HU0103533A patent/HU226688B1/hu not_active IP Right Cessation
- 1999-09-18 RU RU2001111841/04A patent/RU2224748C2/ru not_active IP Right Cessation
- 1999-09-18 AU AU61926/99A patent/AU757689B2/en not_active Ceased
- 1999-09-18 CN CNB99811636XA patent/CN1173951C/zh not_active Expired - Fee Related
- 1999-09-30 AR ARP990104960A patent/AR021845A1/es active IP Right Grant
- 1999-10-01 US US09/410,083 patent/US6596728B1/en not_active Expired - Lifetime
-
2001
- 2001-03-29 ZA ZA200102587A patent/ZA200102587B/en unknown
-
2003
- 2003-05-27 HK HK03103726A patent/HK1051533A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20150918 |