HK1046358A1 - 生長激素配方 - Google Patents

生長激素配方 Download PDF

Info

Publication number
HK1046358A1
HK1046358A1 HK02106653.3A HK02106653A HK1046358A1 HK 1046358 A1 HK1046358 A1 HK 1046358A1 HK 02106653 A HK02106653 A HK 02106653A HK 1046358 A1 HK1046358 A1 HK 1046358A1
Authority
HK
Hong Kong
Prior art keywords
growth hormone
phosphate buffered
buffered solution
formulation
hormone formulations
Prior art date
Application number
HK02106653.3A
Other languages
English (en)
Chinese (zh)
Inventor
Siebold Bernhard
Stevens John
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26315757&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1046358(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9916252.1A external-priority patent/GB9916252D0/en
Priority claimed from GBGB9918902.9A external-priority patent/GB9918902D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HK1046358A1 publication Critical patent/HK1046358A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
HK02106653.3A 1999-07-12 2000-07-11 生長激素配方 HK1046358A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9916252.1 1999-07-12
GBGB9916252.1A GB9916252D0 (en) 1999-07-12 1999-07-12 Growth hormone formulation
GBGB9918902.9A GB9918902D0 (en) 1999-08-12 1999-08-12 Growth hormone formulation
GB9918902.9 1999-08-12
PCT/GB2000/002664 WO2001003741A1 (en) 1999-07-12 2000-07-11 Growth hormone formulations

Publications (1)

Publication Number Publication Date
HK1046358A1 true HK1046358A1 (zh) 2003-01-10

Family

ID=26315757

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02106653.3A HK1046358A1 (zh) 1999-07-12 2000-07-11 生長激素配方

Country Status (25)

Country Link
US (1) US20060029635A1 (OSRAM)
EP (1) EP1194170B1 (OSRAM)
JP (3) JP2003504346A (OSRAM)
KR (1) KR20020031388A (OSRAM)
CN (1) CN1360506A (OSRAM)
AR (1) AR024728A1 (OSRAM)
AT (1) ATE386501T1 (OSRAM)
AU (1) AU775107C (OSRAM)
BR (1) BR0013162A (OSRAM)
CA (1) CA2378949C (OSRAM)
CZ (1) CZ200260A3 (OSRAM)
DE (1) DE60038118T2 (OSRAM)
ES (1) ES2300268T3 (OSRAM)
HK (1) HK1046358A1 (OSRAM)
HU (1) HUP0202189A3 (OSRAM)
IL (2) IL147253A0 (OSRAM)
MX (1) MXPA02000404A (OSRAM)
NO (1) NO20020151L (OSRAM)
NZ (1) NZ516507A (OSRAM)
PL (1) PL353238A1 (OSRAM)
SI (1) SI1194170T1 (OSRAM)
SK (1) SK252002A3 (OSRAM)
TR (1) TR200200034T2 (OSRAM)
TW (1) TWI247608B (OSRAM)
WO (1) WO2001003741A1 (OSRAM)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030162711A1 (en) * 1996-04-24 2003-08-28 Soren Bjorn Pharmaceutical formulation
US20070179096A1 (en) * 1996-04-24 2007-08-02 Novo Nordisk A/S Pharmaceutical Formulation
GB2371227A (en) * 2001-01-10 2002-07-24 Grandis Biotech Gmbh Crystallisation - resistant aqueous growth hormone formulations
CA2491685A1 (en) * 2002-07-09 2004-01-15 Sandoz Ag Liquid formulations with high concentration of human growth hormone (hgh) comprising 1,2-prolpylene glycol
JP4949828B2 (ja) * 2003-03-18 2012-06-13 アレス トレーディング ソシエテ アノニム 溶液中での成長ホルモンの安定化
CA2540172A1 (en) * 2003-09-25 2005-03-31 Cangene Corporation Liquid human growth hormone formulation containing polyethylene glycol
US8338374B2 (en) 2003-12-23 2012-12-25 Pharmacia Corporation Stable growth hormone liquid formulation
JP4991522B2 (ja) * 2004-04-07 2012-08-01 アレス トレーディング ソシエテ アノニム 成長ホルモン液剤
US8293532B2 (en) 2009-03-26 2012-10-23 Dow AgroSciences, L.L.C. Method and apparatus for tissue transfer
CA2780554C (en) * 2009-11-17 2017-08-15 Ipsen Pharma S.A.S. Formulation for hgh and rhigf-1 combination
JP6363949B2 (ja) 2011-07-25 2018-07-25 サンド アクチェンゲゼルシャフト 少なくとも中性塩および生物薬学的タンパク質を含む、水性製剤
US20130288968A1 (en) * 2012-04-30 2013-10-31 Sun Pharmaceutical Industries Ltd. Leuprolide injection
JP6001401B2 (ja) * 2012-09-28 2016-10-05 ユニ・チャーム株式会社 ウェットティッシュ用薬液及びウェットティッシュ
US10647819B2 (en) 2015-12-10 2020-05-12 Mitsubishi Gas Chemical Company, Inc. Photocurable composition and optical material
JP6172880B1 (ja) * 2017-02-01 2017-08-02 協和発酵キリン株式会社 ダルベポエチンを含む液体医薬組成物
KR20210024082A (ko) 2018-06-25 2021-03-04 제이씨알 파마 가부시키가이샤 단백질 함유 수성 액제
AU2021379990A1 (en) * 2020-11-16 2023-06-29 W. L. Gore & Associates, Inc. Formulations, methods, and pre-filled multi-dose injection devices without cloud point
CN112494638B (zh) * 2020-12-22 2023-12-19 深圳科兴药业有限公司 一种人生长激素注射剂组合物及其制备方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783441A (en) * 1979-04-30 1988-11-08 Hoechst Aktiengesellschaft Aqueous protein solutions stable to denaturation
DE3325223A1 (de) * 1983-07-13 1985-01-24 Hoechst Ag, 6230 Frankfurt Gegen denaturierung bestaendige, waessrige proteinloesungen, verfahren zu ihrer herstellung und ihre verwendung
JPS6270319A (ja) * 1985-07-30 1987-03-31 インタ−ナシヨナル・ミネラルズ・アンド・ケミカル・コ−ポレイシヨン 成長促進ホルモンの安定化
US4857505A (en) * 1987-03-09 1989-08-15 American Cyanamid Company Sustained release compositions for parenteral administration and their use
IL86799A (en) * 1987-07-02 1993-03-15 Kabi Pharmacia Ab Method and device for injection
US5151265A (en) * 1987-11-03 1992-09-29 Genentech, Inc. Gamma interferon formulation
CA1331133C (en) * 1988-03-01 1994-08-02 Michael Jon Pikal Pharmaceutical growth hormone formulations
US5096885A (en) * 1988-04-15 1992-03-17 Genentech, Inc. Human growth hormone formulation
US5763394A (en) * 1988-04-15 1998-06-09 Genentech, Inc. Human growth hormone aqueous formulation
JPH0383931A (ja) * 1989-08-29 1991-04-09 Sumitomo Pharmaceut Co Ltd 低刺激性ｇｒｆ経鼻投与製剤
US5126324A (en) * 1990-06-07 1992-06-30 Genentech, Inc. Method of enhancing growth in patients using combination therapy
US5681814A (en) * 1990-06-07 1997-10-28 Genentech, Inc. Formulated IGF-I Composition
DE69110290T2 (de) * 1990-09-21 1995-10-19 Novonordisk As Adaptor.
SE9201073D0 (sv) * 1992-04-03 1992-04-03 Kabi Pharmacia Ab Protein formulation
IL106524A (en) * 1992-07-31 2000-08-31 Genentech Inc Human growth hormone aqueous formulation
US5334162A (en) * 1993-03-15 1994-08-02 Eli Lilly And Company Cartridge assembly for a lyophilized compound forming a disposable portion of an injector pen and method for same
US5496801A (en) * 1993-12-23 1996-03-05 Allelix Biopharmaceuticals Inc. Parathyroid hormone formulation
US5610134A (en) * 1994-04-15 1997-03-11 Genentech, Inc. Treatment of congestive heart failure
JPH0892125A (ja) * 1994-09-21 1996-04-09 Nippon Chem Res Kk 水性医薬組成物
SE9502927D0 (sv) * 1995-08-24 1995-08-24 Pharmacia Ab Solution containing IGF-I
AUPN801296A0 (en) * 1996-02-12 1996-03-07 Csl Limited Stabilised growth hormone formulation and method of preparation thereof
ATE210461T1 (de) * 1996-02-13 2001-12-15 Searle & Co Zusammensetzungen mit immunosuppressiven wirkungen, welche 5-lipoxygenase-inhibitoren und cyclooxygenase-2-inhibitoren enthalten
ZA9711731B (en) * 1996-12-31 1998-07-01 Monsanto Co Aqueous glycerol formulations of somatotropin
TW518235B (en) * 1997-01-15 2003-01-21 Akzo Nobel Nv A gonadotropin-containing pharmaceutical composition with improved stability on prolong storage
JP3723857B2 (ja) * 1998-02-04 2005-12-07 日本ケミカルリサーチ株式会社 ヒト成長ホルモン含有水性医薬組成物

Also Published As

Publication number Publication date
DE60038118T2 (de) 2009-03-05
AR024728A1 (es) 2002-10-23
CN1360506A (zh) 2002-07-24
ES2300268T3 (es) 2008-06-16
CA2378949C (en) 2015-03-31
AU775107C (en) 2005-02-24
WO2001003741B1 (en) 2001-04-19
JP5941496B2 (ja) 2016-06-29
EP1194170B1 (en) 2008-02-20
AU5997500A (en) 2001-01-30
US20060029635A1 (en) 2006-02-09
JP2003504346A (ja) 2003-02-04
ATE386501T1 (de) 2008-03-15
NZ516507A (en) 2004-02-27
PL353238A1 (en) 2003-11-03
CA2378949A1 (en) 2001-01-18
AU775107B2 (en) 2004-07-15
SI1194170T1 (sl) 2008-10-31
BR0013162A (pt) 2002-05-28
SK252002A3 (en) 2002-06-04
NO20020151L (no) 2002-03-12
HUP0202189A2 (en) 2002-10-28
NO20020151D0 (no) 2002-01-11
HUP0202189A3 (en) 2003-07-28
KR20020031388A (ko) 2002-05-01
WO2001003741A1 (en) 2001-01-18
MXPA02000404A (es) 2004-05-21
IL147253A0 (en) 2002-08-14
JP2012051891A (ja) 2012-03-15
EP1194170A1 (en) 2002-04-10
JP2014208656A (ja) 2014-11-06
CZ200260A3 (cs) 2002-04-17
TR200200034T2 (tr) 2002-05-21
IL147253A (en) 2007-07-24
TWI247608B (en) 2006-01-21
DE60038118D1 (de) 2008-04-03

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