HK1040201A1 - 包含性激素和環糊精的鼻用噴霧溶液的製備方法 - Google Patents

包含性激素和環糊精的鼻用噴霧溶液的製備方法 Download PDF

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Publication number
HK1040201A1
HK1040201A1 HK02102010.0A HK02102010A HK1040201A1 HK 1040201 A1 HK1040201 A1 HK 1040201A1 HK 02102010 A HK02102010 A HK 02102010A HK 1040201 A1 HK1040201 A1 HK 1040201A1
Authority
HK
Hong Kong
Prior art keywords
solution
cyclodextrin
estradiol
process according
hormone
Prior art date
Application number
HK02102010.0A
Other languages
English (en)
Chinese (zh)
Inventor
G‧方克奈什坦
P‧乌斯里希
P‧烏斯裡希
Original Assignee
瑟维尔实验室
瑟維爾實驗室
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 瑟维尔实验室, 瑟維爾實驗室 filed Critical 瑟维尔实验室
Publication of HK1040201A1 publication Critical patent/HK1040201A1/zh

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK02102010.0A 1998-10-14 1999-10-13 包含性激素和環糊精的鼻用噴霧溶液的製備方法 HK1040201A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9812836A FR2784584B1 (fr) 1998-10-14 1998-10-14 Procede de preparation d'une solution pour pulverisation nasale contenant une ou plusieurs hormones sexuelles et une cyclodextrine
FR98/12836 1998-10-14
PCT/FR1999/002480 WO2000021503A1 (fr) 1998-10-14 1999-10-13 Procede de preparation d'une solution pour pulverisation nasale contenant une ou plusieurs hormones sexuelles et une cyclodextrine

Publications (1)

Publication Number Publication Date
HK1040201A1 true HK1040201A1 (zh) 2002-05-31

Family

ID=9531516

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02102010.0A HK1040201A1 (zh) 1998-10-14 1999-10-13 包含性激素和環糊精的鼻用噴霧溶液的製備方法

Country Status (21)

Country Link
EP (1) EP1121100B1 (enExample)
JP (1) JP3911125B2 (enExample)
KR (1) KR100462441B1 (enExample)
CN (1) CN1323198A (enExample)
AT (1) ATE237310T1 (enExample)
AU (1) AU756441B2 (enExample)
BR (1) BR9914532A (enExample)
CA (1) CA2346567C (enExample)
DE (1) DE69907005T2 (enExample)
DK (1) DK1121100T3 (enExample)
EA (1) EA003069B1 (enExample)
ES (1) ES2197672T3 (enExample)
FR (1) FR2784584B1 (enExample)
HK (1) HK1040201A1 (enExample)
HU (1) HUP0103968A3 (enExample)
NO (1) NO20011673L (enExample)
NZ (1) NZ510776A (enExample)
PL (1) PL347322A1 (enExample)
PT (1) PT1121100E (enExample)
WO (1) WO2000021503A1 (enExample)
ZA (1) ZA200102961B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2827516B1 (fr) * 2001-07-19 2003-09-19 Servier Lab Composition pharmaceutique pour l'administration par voie nasale d'estradiol et de norethisterone
WO2005018607A1 (ja) * 2003-08-20 2005-03-03 Ajinomoto Co., Inc. 溶解性を改善した医薬品製剤
GB2482868A (en) * 2010-08-16 2012-02-22 Franciscus Wilhelmus Henricus Maria Merkus A testosterone liquid spray formulation for oromucosal administration
WO2013052849A2 (en) * 2011-10-07 2013-04-11 Florida State University Research Foundation Prophylactic and post-acute use of progesterone to better outcomes associated with concussion
WO2013107515A1 (en) 2012-01-20 2013-07-25 Okapi Sciences Nv Eye drop composition
RU2753511C2 (ru) * 2017-05-31 2021-08-17 Аратана Терапьютикс, Инк. Композиция глазных капель

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8801670A (nl) * 1988-07-01 1990-02-01 Walter Adrianus Josephus Johan Farmaceutisch preparaat.
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
GB9012663D0 (en) * 1990-06-07 1990-08-01 Erba Carlo Spa Galenic formulations containing cyclodextrins
DE4207922A1 (de) * 1992-03-13 1993-09-23 Pharmatech Gmbh Wasserloesliche einschlussverbindungen und verfahren zu deren herstellung
BE1007402A5 (nl) * 1993-03-26 1995-06-06 Adir Nasale farmaceutische preparaten met progestagene stof.

Also Published As

Publication number Publication date
HUP0103968A3 (en) 2002-06-28
FR2784584B1 (fr) 2002-09-20
FR2784584A1 (fr) 2000-04-21
CA2346567A1 (fr) 2000-04-20
ZA200102961B (en) 2001-11-20
NZ510776A (en) 2002-10-25
NO20011673D0 (no) 2001-04-03
PT1121100E (pt) 2003-07-31
ATE237310T1 (de) 2003-05-15
DE69907005D1 (de) 2003-05-22
JP2002527374A (ja) 2002-08-27
KR100462441B1 (ko) 2004-12-17
KR20010073214A (ko) 2001-07-31
EA003069B1 (ru) 2002-12-26
CA2346567C (fr) 2005-06-14
AU756441B2 (en) 2003-01-16
CN1323198A (zh) 2001-11-21
BR9914532A (pt) 2001-11-06
EA200100316A1 (ru) 2002-02-28
AU6096799A (en) 2000-05-01
DE69907005T2 (de) 2004-03-18
EP1121100B1 (fr) 2003-04-16
WO2000021503A1 (fr) 2000-04-20
HUP0103968A2 (hu) 2002-04-29
DK1121100T3 (da) 2003-07-21
ES2197672T3 (es) 2004-01-01
NO20011673L (no) 2001-04-03
JP3911125B2 (ja) 2007-05-09
EP1121100A1 (fr) 2001-08-08
PL347322A1 (en) 2002-03-25

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