DK1121100T3 - Fremgangsmåde til fremstilling af en opløsning til næsespray indeholdende kønshormoner og et cyclodextrin - Google Patents

Fremgangsmåde til fremstilling af en opløsning til næsespray indeholdende kønshormoner og et cyclodextrin

Info

Publication number
DK1121100T3
DK1121100T3 DK99947567T DK99947567T DK1121100T3 DK 1121100 T3 DK1121100 T3 DK 1121100T3 DK 99947567 T DK99947567 T DK 99947567T DK 99947567 T DK99947567 T DK 99947567T DK 1121100 T3 DK1121100 T3 DK 1121100T3
Authority
DK
Denmark
Prior art keywords
cyclodextrin
preparing
nasal spray
solution
sex hormones
Prior art date
Application number
DK99947567T
Other languages
English (en)
Inventor
Gilles Fonknechten
Patrick Wuthrich
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Application granted granted Critical
Publication of DK1121100T3 publication Critical patent/DK1121100T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK99947567T 1998-10-14 1999-10-13 Fremgangsmåde til fremstilling af en opløsning til næsespray indeholdende kønshormoner og et cyclodextrin DK1121100T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9812836A FR2784584B1 (fr) 1998-10-14 1998-10-14 Procede de preparation d'une solution pour pulverisation nasale contenant une ou plusieurs hormones sexuelles et une cyclodextrine
PCT/FR1999/002480 WO2000021503A1 (fr) 1998-10-14 1999-10-13 Procede de preparation d'une solution pour pulverisation nasale contenant une ou plusieurs hormones sexuelles et une cyclodextrine

Publications (1)

Publication Number Publication Date
DK1121100T3 true DK1121100T3 (da) 2003-07-21

Family

ID=9531516

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99947567T DK1121100T3 (da) 1998-10-14 1999-10-13 Fremgangsmåde til fremstilling af en opløsning til næsespray indeholdende kønshormoner og et cyclodextrin

Country Status (21)

Country Link
EP (1) EP1121100B1 (da)
JP (1) JP3911125B2 (da)
KR (1) KR100462441B1 (da)
CN (1) CN1323198A (da)
AT (1) ATE237310T1 (da)
AU (1) AU756441B2 (da)
BR (1) BR9914532A (da)
CA (1) CA2346567C (da)
DE (1) DE69907005T2 (da)
DK (1) DK1121100T3 (da)
EA (1) EA003069B1 (da)
ES (1) ES2197672T3 (da)
FR (1) FR2784584B1 (da)
HK (1) HK1040201A1 (da)
HU (1) HUP0103968A3 (da)
NO (1) NO20011673D0 (da)
NZ (1) NZ510776A (da)
PL (1) PL347322A1 (da)
PT (1) PT1121100E (da)
WO (1) WO2000021503A1 (da)
ZA (1) ZA200102961B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2827516B1 (fr) * 2001-07-19 2003-09-19 Servier Lab Composition pharmaceutique pour l'administration par voie nasale d'estradiol et de norethisterone
JPWO2005018607A1 (ja) * 2003-08-20 2007-11-01 味の素株式会社 溶解性を改善した医薬品製剤
GB2482868A (en) * 2010-08-16 2012-02-22 Franciscus Wilhelmus Henricus Maria Merkus A testosterone liquid spray formulation for oromucosal administration
AU2012318391A1 (en) * 2011-10-07 2014-05-15 Florida State University Research Foundation Prophylactic and post-acute use of progesterone to better outcomes associated with concussion
BR112014017163A8 (pt) * 2012-01-20 2017-07-04 Aratana Therapeutics Nv composição de colírio
RU2753511C2 (ru) * 2017-05-31 2021-08-17 Аратана Терапьютикс, Инк. Композиция глазных капель

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8801670A (nl) * 1988-07-01 1990-02-01 Walter Adrianus Josephus Johan Farmaceutisch preparaat.
US5376645A (en) * 1990-01-23 1994-12-27 University Of Kansas Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof
GB9012663D0 (en) * 1990-06-07 1990-08-01 Erba Carlo Spa Galenic formulations containing cyclodextrins
DE4207922A1 (de) * 1992-03-13 1993-09-23 Pharmatech Gmbh Wasserloesliche einschlussverbindungen und verfahren zu deren herstellung
BE1007402A5 (nl) * 1993-03-26 1995-06-06 Adir Nasale farmaceutische preparaten met progestagene stof.

Also Published As

Publication number Publication date
EA200100316A1 (ru) 2002-02-28
JP3911125B2 (ja) 2007-05-09
ES2197672T3 (es) 2004-01-01
PT1121100E (pt) 2003-07-31
KR20010073214A (ko) 2001-07-31
PL347322A1 (en) 2002-03-25
HUP0103968A3 (en) 2002-06-28
AU756441B2 (en) 2003-01-16
CA2346567A1 (fr) 2000-04-20
ATE237310T1 (de) 2003-05-15
HUP0103968A2 (hu) 2002-04-29
CN1323198A (zh) 2001-11-21
DE69907005D1 (de) 2003-05-22
CA2346567C (fr) 2005-06-14
FR2784584A1 (fr) 2000-04-21
HK1040201A1 (zh) 2002-05-31
AU6096799A (en) 2000-05-01
WO2000021503A1 (fr) 2000-04-20
JP2002527374A (ja) 2002-08-27
KR100462441B1 (ko) 2004-12-17
DE69907005T2 (de) 2004-03-18
NO20011673L (no) 2001-04-03
ZA200102961B (en) 2001-11-20
EP1121100B1 (fr) 2003-04-16
NZ510776A (en) 2002-10-25
NO20011673D0 (no) 2001-04-03
FR2784584B1 (fr) 2002-09-20
EP1121100A1 (fr) 2001-08-08
BR9914532A (pt) 2001-11-06
EA003069B1 (ru) 2002-12-26

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