HK1037879A1 - Separation of antibody monomers from its multimersby use of ion-exchange chromatography. - Google Patents

Separation of antibody monomers from its multimersby use of ion-exchange chromatography.

Info

Publication number
HK1037879A1
HK1037879A1 HK01106713A HK01106713A HK1037879A1 HK 1037879 A1 HK1037879 A1 HK 1037879A1 HK 01106713 A HK01106713 A HK 01106713A HK 01106713 A HK01106713 A HK 01106713A HK 1037879 A1 HK1037879 A1 HK 1037879A1
Authority
HK
Hong Kong
Prior art keywords
exchange chromatography
multimersby
ion
separation
mixture
Prior art date
Application number
HK01106713A
Other languages
English (en)
Inventor
Philip Lester
Deborah Ansaldi
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22206161&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1037879(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of HK1037879A1 publication Critical patent/HK1037879A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK01106713A 1998-06-01 2001-09-21 Separation of antibody monomers from its multimersby use of ion-exchange chromatography. HK1037879A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8760298P 1998-06-01 1998-06-01
PCT/US1999/011598 WO1999062936A1 (fr) 1998-06-01 1999-05-24 Separation des monomeres proteiques des agregats par l'utilisation de la chromatographie d'echange d'ions

Publications (1)

Publication Number Publication Date
HK1037879A1 true HK1037879A1 (en) 2002-02-22

Family

ID=22206161

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01106713A HK1037879A1 (en) 1998-06-01 2001-09-21 Separation of antibody monomers from its multimersby use of ion-exchange chromatography.

Country Status (13)

Country Link
US (2) US6620918B2 (fr)
EP (2) EP1500661A1 (fr)
JP (3) JP2002517406A (fr)
AT (1) ATE274522T1 (fr)
AU (1) AU750977B2 (fr)
CA (1) CA2333747C (fr)
DE (1) DE69919701T2 (fr)
DK (1) DK1084136T3 (fr)
ES (1) ES2228052T3 (fr)
HK (1) HK1037879A1 (fr)
IL (2) IL139609A (fr)
PT (1) PT1084136E (fr)
WO (1) WO1999062936A1 (fr)

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KR101516054B1 (ko) * 2012-11-21 2015-05-06 씨제이헬스케어 주식회사 신규한 지속형 인간 성장호르몬 단량체를 제조하는 방법
CN105073769B (zh) 2013-03-14 2019-09-10 Emd密理博公司 利用基于a蛋白的色谱增加蛋白纯度的方法
AR096713A1 (es) * 2013-06-25 2016-01-27 Cadila Healthcare Ltd Proceso de purificación para anticuerpos monoclonales
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EP3603764B1 (fr) * 2015-04-28 2022-03-30 Hybio Pharmaceutical Co., Ltd. Methode de chromatographie liquide a haute performance pour des melanges de polypeptides
JP2018524595A (ja) * 2015-07-14 2018-08-30 イエダ リサーチ アンド ディベロップメント カンパニー リミテッド 統合失調症の診断で使用するためのペプチドの組み合わせ
JP6749590B2 (ja) * 2015-09-17 2020-09-02 国立大学法人 東京大学 酸化型及び還元型アルブミンの分析方法、酸化型及び還元型アルブミンの分析装置、及び酸化型及び還元型アルブミンの分析キット
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WO2022207615A1 (fr) 2021-03-31 2022-10-06 F. Hoffmann-La Roche Ag Purification d'anticorps par chromatographie en mode mixte

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Also Published As

Publication number Publication date
JP2006071646A (ja) 2006-03-16
AU4205999A (en) 1999-12-20
AU750977B2 (en) 2002-08-01
JP2002517406A (ja) 2002-06-18
ES2228052T3 (es) 2005-04-01
JP2004175806A (ja) 2004-06-24
DK1084136T3 (da) 2005-01-03
DE69919701D1 (de) 2004-09-30
EP1084136B1 (fr) 2004-08-25
ATE274522T1 (de) 2004-09-15
IL139609A (en) 2006-06-11
US20020010319A1 (en) 2002-01-24
EP1084136A1 (fr) 2001-03-21
CA2333747A1 (fr) 1999-12-09
US20040116674A1 (en) 2004-06-17
DE69919701T2 (de) 2005-09-15
EP1500661A1 (fr) 2005-01-26
CA2333747C (fr) 2008-02-19
IL173432A0 (en) 2006-06-11
IL139609A0 (en) 2002-02-10
WO1999062936A1 (fr) 1999-12-09
US6620918B2 (en) 2003-09-16
PT1084136E (pt) 2004-12-31

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20080524