DK1084136T3 - Adskillelse af monomere af et antistof fra dets multimere ved anvendelse af ionbytterchromatografi - Google Patents

Adskillelse af monomere af et antistof fra dets multimere ved anvendelse af ionbytterchromatografi

Info

Publication number
DK1084136T3
DK1084136T3 DK99925856T DK99925856T DK1084136T3 DK 1084136 T3 DK1084136 T3 DK 1084136T3 DK 99925856 T DK99925856 T DK 99925856T DK 99925856 T DK99925856 T DK 99925856T DK 1084136 T3 DK1084136 T3 DK 1084136T3
Authority
DK
Denmark
Prior art keywords
multimers
monomers
exchange chromatography
antibody
separation
Prior art date
Application number
DK99925856T
Other languages
Danish (da)
English (en)
Inventor
Philip Lester
Deborah Ansaldi
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22206161&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1084136(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DK1084136T3 publication Critical patent/DK1084136T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • C07K14/765Serum albumin, e.g. HSA
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4283Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
    • C07K16/4291Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK99925856T 1998-06-01 1999-05-24 Adskillelse af monomere af et antistof fra dets multimere ved anvendelse af ionbytterchromatografi DK1084136T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8760298P 1998-06-01 1998-06-01
EP99925856A EP1084136B1 (fr) 1998-06-01 1999-05-24 Separation des monomeres d'un anticorps de ses multimeres par l'utilisation de la chromatographie echangeuse d'ions

Publications (1)

Publication Number Publication Date
DK1084136T3 true DK1084136T3 (da) 2005-01-03

Family

ID=22206161

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99925856T DK1084136T3 (da) 1998-06-01 1999-05-24 Adskillelse af monomere af et antistof fra dets multimere ved anvendelse af ionbytterchromatografi

Country Status (13)

Country Link
US (2) US6620918B2 (fr)
EP (2) EP1500661A1 (fr)
JP (3) JP2002517406A (fr)
AT (1) ATE274522T1 (fr)
AU (1) AU750977B2 (fr)
CA (1) CA2333747C (fr)
DE (1) DE69919701T2 (fr)
DK (1) DK1084136T3 (fr)
ES (1) ES2228052T3 (fr)
HK (1) HK1037879A1 (fr)
IL (2) IL139609A (fr)
PT (1) PT1084136E (fr)
WO (1) WO1999062936A1 (fr)

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EP2226331A4 (fr) 2007-10-26 2012-02-08 Asahi Kasei Chemicals Corp Methode de purification de proteines
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CN101948528B (zh) * 2010-09-26 2012-02-01 广东工业大学 一种来自斑蝥的纤溶活性蛋白及其制备方法和应用
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PL221899B1 (pl) * 2011-05-06 2016-06-30 Wrocławskie Centrum Badań Eit + Spółka Z Ograniczoną Czysta albumina oraz sposób jej otrzymywania i detekcji
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KR101516054B1 (ko) * 2012-11-21 2015-05-06 씨제이헬스케어 주식회사 신규한 지속형 인간 성장호르몬 단량체를 제조하는 방법
CN105073769B (zh) 2013-03-14 2019-09-10 Emd密理博公司 利用基于a蛋白的色谱增加蛋白纯度的方法
AR096713A1 (es) * 2013-06-25 2016-01-27 Cadila Healthcare Ltd Proceso de purificación para anticuerpos monoclonales
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EP3603764B1 (fr) * 2015-04-28 2022-03-30 Hybio Pharmaceutical Co., Ltd. Methode de chromatographie liquide a haute performance pour des melanges de polypeptides
JP2018524595A (ja) * 2015-07-14 2018-08-30 イエダ リサーチ アンド ディベロップメント カンパニー リミテッド 統合失調症の診断で使用するためのペプチドの組み合わせ
JP6749590B2 (ja) * 2015-09-17 2020-09-02 国立大学法人 東京大学 酸化型及び還元型アルブミンの分析方法、酸化型及び還元型アルブミンの分析装置、及び酸化型及び還元型アルブミンの分析キット
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Also Published As

Publication number Publication date
JP2006071646A (ja) 2006-03-16
AU4205999A (en) 1999-12-20
AU750977B2 (en) 2002-08-01
JP2002517406A (ja) 2002-06-18
ES2228052T3 (es) 2005-04-01
JP2004175806A (ja) 2004-06-24
DE69919701D1 (de) 2004-09-30
EP1084136B1 (fr) 2004-08-25
HK1037879A1 (en) 2002-02-22
ATE274522T1 (de) 2004-09-15
IL139609A (en) 2006-06-11
US20020010319A1 (en) 2002-01-24
EP1084136A1 (fr) 2001-03-21
CA2333747A1 (fr) 1999-12-09
US20040116674A1 (en) 2004-06-17
DE69919701T2 (de) 2005-09-15
EP1500661A1 (fr) 2005-01-26
CA2333747C (fr) 2008-02-19
IL173432A0 (en) 2006-06-11
IL139609A0 (en) 2002-02-10
WO1999062936A1 (fr) 1999-12-09
US6620918B2 (en) 2003-09-16
PT1084136E (pt) 2004-12-31

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