HK1033309A1 - Glucocorticoid-selective antiinflammatory agents - Google Patents

Glucocorticoid-selective antiinflammatory agents

Info

Publication number
HK1033309A1
HK1033309A1 HK01102795A HK01102795A HK1033309A1 HK 1033309 A1 HK1033309 A1 HK 1033309A1 HK 01102795 A HK01102795 A HK 01102795A HK 01102795 A HK01102795 A HK 01102795A HK 1033309 A1 HK1033309 A1 HK 1033309A1
Authority
HK
Hong Kong
Prior art keywords
glucocorticoid
mammal
antiinflammatory agents
compounds
formula
Prior art date
Application number
HK01102795A
Other languages
English (en)
Inventor
Michael J Coughlan
Michael E Kort
James P Edwards
Todd K Jones
Original Assignee
Abbott Lab
Ligand Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab, Ligand Pharm Inc filed Critical Abbott Lab
Publication of HK1033309A1 publication Critical patent/HK1033309A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
HK01102795A 1998-02-13 2001-04-19 Glucocorticoid-selective antiinflammatory agents HK1033309A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/023,913 US6380207B2 (en) 1998-02-13 1998-02-13 Glucocortiocoid-selective antiinflammatory agents
PCT/US1999/003210 WO1999041257A1 (en) 1998-02-13 1999-02-15 Glucocorticoid-selective antiinflammatory agents

Publications (1)

Publication Number Publication Date
HK1033309A1 true HK1033309A1 (en) 2001-08-24

Family

ID=21817891

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01102795A HK1033309A1 (en) 1998-02-13 2001-04-19 Glucocorticoid-selective antiinflammatory agents

Country Status (24)

Country Link
US (1) US6380207B2 (no)
EP (1) EP1053240B1 (no)
JP (1) JP2002503666A (no)
KR (1) KR20010040940A (no)
CN (1) CN1153771C (no)
AT (1) ATE237620T1 (no)
AU (1) AU760511B2 (no)
BG (1) BG64213B1 (no)
BR (1) BR9907847A (no)
CA (1) CA2320911A1 (no)
DE (1) DE69906938T2 (no)
DK (1) DK1053240T3 (no)
ES (1) ES2197618T3 (no)
HK (1) HK1033309A1 (no)
HU (1) HUP0100846A3 (no)
IL (1) IL137509A0 (no)
NO (1) NO20004052L (no)
NZ (1) NZ506012A (no)
PL (1) PL342999A1 (no)
PT (1) PT1053240E (no)
SK (1) SK284076B6 (no)
TR (1) TR200002345T2 (no)
WO (1) WO1999041257A1 (no)
ZA (1) ZA99533B (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6566372B1 (en) * 1999-08-27 2003-05-20 Ligand Pharmaceuticals Incorporated Bicyclic androgen and progesterone receptor modulator compounds and methods
ES2246292T3 (es) 2000-10-30 2006-02-16 Pfizer Products Inc. Moduladores de receptor glucocorticoide.
US7026484B2 (en) * 2001-02-23 2006-04-11 Ligand Pharmaceuticals Incorporated Tricyclic androgen receptor modulator compounds and methods
CA2473886C (en) 2002-01-22 2012-08-21 The Regents Of The University Of California Non-steroidal ligands for the glucocorticoid receptor, compositions and uses thereof
KR100492913B1 (ko) * 2002-08-23 2005-06-03 주식회사 태평양 피부 감작 및 자극을 완화하는 피부 외용제 조성물
JP2006506445A (ja) 2002-08-28 2006-02-23 ホリス − イーデン ファーマスーティカルズ、 インコーポレイテッド 治療処置の方法
US20040220153A1 (en) * 2002-09-24 2004-11-04 Jost-Price Edward Roydon Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
DE20301728U1 (de) * 2002-10-11 2004-03-11 Ligand Pharmaceuticals, Inc., San Diego 5-substituierte 7,9-Difluor-5H-Chromeno(3,4-f) -Chinolin-Verbindungen als selektive Progesteronrezeptormodulator-Verbindungen
CA2501833A1 (en) * 2002-10-11 2004-04-22 Ligand Pharmaceuticals Incorporated 5-(1',1'-cycloalkyl/alkenyl)methylidene 1,2-dihydro-5h-chromeno[3,4-f]quinolines as selective progesterone receptor modulator compounds
HK1055058A2 (en) * 2002-10-11 2003-12-05 Ligand Pharm Inc 5-CYCLOALKENYL 5H-CHROMENO[3,4-f]QUINOLINE DERIVATIVES AS SELECTIVE PROGESTERONE RECEPTOR MODULATOR COMPOUNDS
US7235662B2 (en) * 2003-06-11 2007-06-26 Bristol-Myers Squibb Company Modulators of the glucocorticoid receptor and method
JP4709759B2 (ja) 2003-08-22 2011-06-22 リガンド・ファーマシューティカルズ・インコーポレイテッド アンドロゲン受容体モジュレーター化合物としての6−シクロアミノ−2−キノリノン誘導体
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
CA2546347A1 (en) 2003-11-21 2005-06-09 Combinatorx, Incorporated Methods and reagents for the treatment of inflammatory disorders
WO2005090282A1 (en) * 2004-03-12 2005-09-29 Ligand Pharmaceuticals Incorporated Androgen receptor modulator compounds and methods
JP5199079B2 (ja) 2005-06-17 2013-05-15 リガンド・ファーマシューティカルズ・インコーポレイテッド アンドロゲン受容体モジュレーター化合物および方法
EP1916896A4 (en) 2005-08-26 2010-08-11 Univ California NOT STEROID-antiandrogens
TWI435729B (zh) 2005-11-09 2014-05-01 Combinatorx Inc 治療病症之方法,組合物及套組
CN101326155B (zh) * 2005-12-09 2012-06-20 霍夫曼-拉罗奇有限公司 作为抗炎剂的丙酰胺化合物
CA2632109A1 (en) * 2005-12-09 2007-06-14 F. Hoffmann-La Roche Ag Glucocorticoid receptor modulators as antiinflammatory agents
US20100092479A1 (en) * 2008-08-18 2010-04-15 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
US9908182B2 (en) 2012-01-30 2018-03-06 Black & Decker Inc. Remote programming of a power tool
US8919456B2 (en) 2012-06-08 2014-12-30 Black & Decker Inc. Fastener setting algorithm for drill driver
US10011006B2 (en) 2013-08-08 2018-07-03 Black & Decker Inc. Fastener setting algorithm for drill driver

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5696127A (en) 1994-12-22 1997-12-09 Ligand Pharmaceuticals Incorporated Steroid receptor modulator compounds and methods
DK0800519T3 (da) 1994-12-22 2004-03-01 Ligand Pharm Inc Steroidreceptormodulatorforbindelser og fremgangsmåder
US5693133A (en) 1995-05-10 1997-12-02 Akzo Nobel Nv Asbestos free roof coatings

Also Published As

Publication number Publication date
EP1053240B1 (en) 2003-04-16
AU760511B2 (en) 2003-05-15
NZ506012A (en) 2003-03-28
PL342999A1 (en) 2001-07-16
BR9907847A (pt) 2001-01-09
DK1053240T3 (da) 2003-08-11
DE69906938D1 (de) 2003-05-22
IL137509A0 (en) 2001-07-24
HUP0100846A2 (hu) 2001-09-28
US6380207B2 (en) 2002-04-30
CN1153771C (zh) 2004-06-16
CN1297451A (zh) 2001-05-30
JP2002503666A (ja) 2002-02-05
WO1999041257A1 (en) 1999-08-19
CA2320911A1 (en) 1999-08-19
DE69906938T2 (de) 2004-02-26
SK284076B6 (sk) 2004-09-08
NO20004052D0 (no) 2000-08-11
BG64213B1 (bg) 2004-05-31
EP1053240A1 (en) 2000-11-22
ATE237620T1 (de) 2003-05-15
ES2197618T3 (es) 2004-01-01
TR200002345T2 (tr) 2000-11-21
ZA99533B (en) 1999-07-26
PT1053240E (pt) 2003-09-30
SK11962000A3 (sk) 2001-03-12
HUP0100846A3 (en) 2003-03-28
BG104698A (en) 2001-05-31
US20010049377A1 (en) 2001-12-06
AU2600399A (en) 1999-08-30
KR20010040940A (ko) 2001-05-15
NO20004052L (no) 2000-10-12

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20070215