HK1031383A1 - 2-Halo-5-o-substituted ketolide derivatives - Google Patents

2-Halo-5-o-substituted ketolide derivatives

Info

Publication number
HK1031383A1
HK1031383A1 HK01100816A HK01100816A HK1031383A1 HK 1031383 A1 HK1031383 A1 HK 1031383A1 HK 01100816 A HK01100816 A HK 01100816A HK 01100816 A HK01100816 A HK 01100816A HK 1031383 A1 HK1031383 A1 HK 1031383A1
Authority
HK
Hong Kong
Prior art keywords
halo
ketolide derivatives
substituted ketolide
substituted
derivatives
Prior art date
Application number
HK01100816A
Other languages
English (en)
Inventor
Ly Tam Phan
Yat Sun Or
Daniel T Chu
Jacob J Plattner
Richard F Clark
Yan Chen
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of HK1031383A1 publication Critical patent/HK1031383A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
HK01100816A 1997-10-29 2001-02-05 2-Halo-5-o-substituted ketolide derivatives HK1031383A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95988197A 1997-10-29 1997-10-29
US15423998A 1998-09-16 1998-09-16
PCT/US1998/022989 WO1999021871A1 (en) 1997-10-29 1998-10-29 2-halo-6-o-substituted ketolide derivatives

Publications (1)

Publication Number Publication Date
HK1031383A1 true HK1031383A1 (en) 2001-06-15

Family

ID=26851273

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01100816A HK1031383A1 (en) 1997-10-29 2001-02-05 2-Halo-5-o-substituted ketolide derivatives

Country Status (25)

Country Link
EP (1) EP1027362B1 (es)
JP (1) JP2001521039A (es)
KR (1) KR100536420B1 (es)
CN (1) CN1240707C (es)
AR (1) AR015994A1 (es)
AT (1) ATE298760T1 (es)
AU (1) AU751448B2 (es)
BG (1) BG64707B1 (es)
BR (1) BR9813319A (es)
CA (1) CA2307788C (es)
CO (1) CO4990960A1 (es)
CZ (1) CZ300063B6 (es)
DE (1) DE69830739T2 (es)
DK (1) DK1027362T3 (es)
ES (1) ES2244094T3 (es)
HK (1) HK1031383A1 (es)
HU (1) HUP0004282A3 (es)
IL (1) IL135519A0 (es)
NO (1) NO20002190L (es)
NZ (1) NZ503822A (es)
PL (1) PL191453B1 (es)
PT (1) PT1027362E (es)
SK (1) SK286397B6 (es)
TR (1) TR200001142T2 (es)
WO (1) WO1999021871A1 (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39743E1 (en) * 1998-10-15 2007-07-24 Aventis Pharma S.A. 2-halogenated derivatives of 5-0 desosaminyl-erythronolide a, their preparation process and their antibiotic use
FR2784682B1 (fr) 1998-10-15 2002-12-06 Hoechst Marion Roussel Inc Nouveaux derives 2-halogene de 5-0-desosaminylerythronolide a, leur procede de preparation et leur application comme medicaments
KR100710605B1 (ko) 1999-04-16 2007-04-24 코산 바이오사이언시즈, 인코포레이티드 매크롤라이드 항감염제
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
ES2306674T3 (es) * 1999-12-02 2008-11-16 Abbott Laboratories Derivados cetolidos 6-o-alquil-2-nor-2-sustituidos.
US6569836B2 (en) 1999-12-02 2003-05-27 Abbott Laboratories 6-O-alkyl-2-nor-2-substituted ketolide derivatives
JP2001261694A (ja) 2000-03-06 2001-09-26 Pfizer Prod Inc ケトライド抗生物質
US6605707B1 (en) 2000-03-23 2003-08-12 Abbott Laboratories Process for the preparation of 6-O-propargyl erythromycin derivatives
EP1167376B1 (en) 2000-06-30 2004-07-14 Pfizer Products Inc. Macrolide antibiotics
US6472372B1 (en) * 2000-12-06 2002-10-29 Ortho-Mcneil Pharmaceuticals, Inc. 6-O-Carbamoyl ketolide antibacterials
US6713455B2 (en) 2001-09-17 2004-03-30 Ortho-Mcneil Pharmaceutical, Inc. 6-O-carbamate-11,12-lacto-ketolide antimicrobials
HUP0500018A3 (en) 2001-12-05 2009-09-28 Ortho Mcneil Pharm Inc 6-o-acyl ketolide derivatives of erythromycine processes for preparing them and using them as antibacterials
JP2005522453A (ja) * 2002-02-13 2005-07-28 アボット・ラボラトリーズ マクロライド抗菌化合物
WO2003090761A1 (en) * 2002-04-25 2003-11-06 Abbott Laboratories 9-oxime macrolide antibacterials
JP2005528409A (ja) * 2002-04-25 2005-09-22 アボット・ラボラトリーズ オキソリド抗菌薬
WO2004078771A1 (ja) * 2003-03-07 2004-09-16 Taisho Pharmaceutical Co., Ltd. ２－フルオロ－６－ｏ－置換ケトライド誘導体
JP2007254285A (ja) * 2004-03-16 2007-10-04 Taisho Pharmaceut Co Ltd ２−フルオロ−６−ｏ−置換ケトライド誘導体
CN102459296B (zh) * 2009-05-27 2014-10-29 沃克哈特研究中心 具有抗微生物活性的酮内酯类化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
US5591837A (en) * 1992-04-22 1997-01-07 Taisho Pharmaceutical Co., Ltd. 5-O-desosaminylerythronolide a derivative
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments

Also Published As

Publication number Publication date
TR200001142T2 (tr) 2000-09-21
BG104434A (en) 2001-01-31
KR100536420B1 (ko) 2005-12-16
AR015994A1 (es) 2001-05-30
WO1999021871A1 (en) 1999-05-06
JP2001521039A (ja) 2001-11-06
NZ503822A (en) 2002-12-20
AU1288199A (en) 1999-05-17
BR9813319A (pt) 2000-08-22
EP1027362B1 (en) 2005-06-29
DE69830739T2 (de) 2006-04-20
BG64707B1 (bg) 2005-12-30
PT1027362E (pt) 2005-08-31
SK6332000A3 (en) 2000-09-12
ES2244094T3 (es) 2005-12-01
ATE298760T1 (de) 2005-07-15
CA2307788C (en) 2008-05-20
CN1283199A (zh) 2001-02-07
EP1027362A1 (en) 2000-08-16
CZ300063B6 (cs) 2009-01-21
SK286397B6 (sk) 2008-09-05
DK1027362T3 (da) 2005-10-31
HUP0004282A3 (en) 2001-10-29
IL135519A0 (en) 2001-05-20
NO20002190D0 (no) 2000-04-27
CZ20001525A3 (cs) 2000-10-11
PL340290A1 (en) 2001-01-29
DE69830739D1 (de) 2005-08-04
NO20002190L (no) 2000-06-29
AU751448B2 (en) 2002-08-15
CA2307788A1 (en) 1999-05-06
HUP0004282A2 (hu) 2001-04-28
CN1240707C (zh) 2006-02-08
KR20010015793A (ko) 2001-02-26
PL191453B1 (pl) 2006-05-31
CO4990960A1 (es) 2000-12-26

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20101029