HK1027350A1 - A new process for the preparation of a pharmacologically active substance - Google Patents
A new process for the preparation of a pharmacologically active substanceInfo
- Publication number
- HK1027350A1 HK1027350A1 HK00106408A HK00106408A HK1027350A1 HK 1027350 A1 HK1027350 A1 HK 1027350A1 HK 00106408 A HK00106408 A HK 00106408A HK 00106408 A HK00106408 A HK 00106408A HK 1027350 A1 HK1027350 A1 HK 1027350A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- preparation
- active substance
- pharmacologically active
- new process
- new
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU9700885A HU222283B1 (hu) | 1997-05-13 | 1997-05-13 | Eljárás tieno[3,2-c]piridin-származékok előállítására |
| PCT/HU1998/000048 WO1998051689A1 (en) | 1997-05-13 | 1998-05-11 | A new process for the preparation of a pharmacologically active substance |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1027350A1 true HK1027350A1 (en) | 2001-01-12 |
Family
ID=90014236
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK00106408A HK1027350A1 (en) | 1997-05-13 | 2000-10-10 | A new process for the preparation of a pharmacologically active substance |
Country Status (38)
| Country | Link |
|---|---|
| US (1) | US6180793B1 (ko) |
| EP (1) | EP0981529B1 (ko) |
| KR (1) | KR100428238B1 (ko) |
| CN (1) | CN1109036C (ko) |
| AR (1) | AR014349A1 (ko) |
| AT (1) | ATE212025T1 (ko) |
| AU (1) | AU735702B2 (ko) |
| BR (1) | BR9809112B1 (ko) |
| CA (1) | CA2289623C (ko) |
| CO (1) | CO4950564A1 (ko) |
| CZ (1) | CZ292820B6 (ko) |
| DE (1) | DE69803176T2 (ko) |
| DK (1) | DK0981529T3 (ko) |
| DZ (1) | DZ2487A1 (ko) |
| EE (1) | EE03925B1 (ko) |
| EG (1) | EG21973A (ko) |
| ES (1) | ES2172141T3 (ko) |
| HK (1) | HK1027350A1 (ko) |
| HR (1) | HRP980240B1 (ko) |
| HU (1) | HU222283B1 (ko) |
| ID (1) | ID23018A (ko) |
| IL (1) | IL132774A0 (ko) |
| IS (1) | IS1883B (ko) |
| ME (1) | ME01636B (ko) |
| MY (1) | MY121299A (ko) |
| NO (1) | NO325419B1 (ko) |
| NZ (1) | NZ501577A (ko) |
| PL (1) | PL194859B1 (ko) |
| PT (1) | PT981529E (ko) |
| RS (1) | RS49626B (ko) |
| RU (1) | RU2172315C1 (ko) |
| SA (1) | SA98190583B1 (ko) |
| SK (1) | SK283700B6 (ko) |
| TR (1) | TR199902783T2 (ko) |
| TW (1) | TW552263B (ko) |
| UA (1) | UA66359C2 (ko) |
| WO (1) | WO1998051689A1 (ko) |
| ZA (1) | ZA983921B (ko) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2769313B1 (fr) * | 1997-10-06 | 2000-04-21 | Sanofi Sa | Derives d'esters hydroxyacetiques, leur procede de preparation et leur utilisation comme intermediaires de synthese |
| HU226421B1 (en) | 1998-11-09 | 2008-12-29 | Sanofi Aventis | Process for racemizing optically active 2-(2-chlorophenyl)-2-(2-(2-thienyl)-ethylamino)-acetamides |
| IN191030B (ko) * | 2001-01-24 | 2003-09-13 | Cadila Healthcare Ltd | |
| US6495691B1 (en) | 2001-07-06 | 2002-12-17 | Brantford Chemicals Inc. | Process for the preparation of tetrahydrothieno[3,2-c]pyridine derivatives |
| US6767913B2 (en) | 2001-12-18 | 2004-07-27 | Teva Pharmaceutical Industries Ltd. | Crystal forms iii, iv, v, and novel amorphous form of clopidogrel hydrogensulfate, processes for their preparation, processes for the preparation of form i, compositions containing the new forms and methods of administering the new forms |
| US7074928B2 (en) | 2002-01-11 | 2006-07-11 | Teva Pharmaceutical Industries, Ltd. | Polymorphs of clopidogrel hydrogensulfate |
| ITMI20020933A1 (it) * | 2002-05-03 | 2003-11-03 | Danimite Dipharma S P A | Procedimento per la sintesi di clopidogrel |
| US6800759B2 (en) * | 2002-08-02 | 2004-10-05 | Teva Pharmaceutical Industries Ltd. | Racemization and enantiomer separation of clopidogrel |
| IL166593A0 (en) | 2002-08-02 | 2006-01-15 | Racemization and enantiomer separation of clopidogrel | |
| US6812363B2 (en) * | 2002-10-15 | 2004-11-02 | Usv Limited | Racemization of optically active 2-substituted phenyl glycine esters |
| WO2004081015A1 (en) * | 2003-03-10 | 2004-09-23 | Hetero Drugs Limited | Amorphous clopidogrel hydrogen sulfate |
| US7872019B2 (en) | 2003-03-12 | 2011-01-18 | Cadila Healthcare Limited | Polymorphs and amorphous form of (S)-(+)-clopidogrel bisulfate |
| GB0321256D0 (en) | 2003-09-11 | 2003-10-08 | Generics Uk Ltd | Novel crystalline compounds |
| WO2005063708A2 (en) | 2003-11-03 | 2005-07-14 | Cadila Healthcare Limited | Processes for preparing different forms of (s)-(+)- clopidogrel bisulfate |
| CA2457459A1 (en) * | 2004-02-11 | 2005-08-11 | Brantford Chemicals Inc. | Resolution of racemates of methyl alpha-5-(4,5,6,7-tetrahydro(3,2-c)thienopyridyl)-(2-chlorophenyl) acetate |
| KR100553398B1 (ko) | 2004-03-12 | 2006-02-16 | 한미약품 주식회사 | 티에노[3,2-ｃ]피리딘 유도체의 제조 방법 및 이에사용되는 중간체 |
| JP2007513889A (ja) * | 2004-09-21 | 2007-05-31 | テバ ファーマシューティカル インダストリーズ リミティド | 結晶性クロピドグレル臭酸塩及びその調製方法 |
| MX2007010267A (es) * | 2005-02-24 | 2007-09-11 | Teva Pharma | Base de clopidogrel adecuada para formulacion farmaceutica y preparacion de ella. |
| KR100681512B1 (ko) | 2005-03-08 | 2007-02-09 | 주식회사 한서켐 | 클로피도그렐의 신규한 제조 중간체 및 이를 이용한 클로피도그렐의 제조방법 |
| KR101235117B1 (ko) | 2005-12-26 | 2013-02-20 | 에스케이케미칼주식회사 | 광학분리에 의한 (ｓ)-(＋)-클로피도그렐의 제조방법 |
| WO2007125544A2 (en) * | 2006-04-27 | 2007-11-08 | Ind-Swift Laboratories Limited | Process for the preparation of polymorphic forms of clopidogrel hydrogen sulfate |
| KR20080055860A (ko) * | 2006-08-03 | 2008-06-19 | 테바 파마슈티컬 인더스트리즈 리미티드 | 클로피도그렐 바이설페이트의 제조 방법 |
| US8247558B2 (en) | 2006-09-04 | 2012-08-21 | Ranbaxy Laboratories Limited | Process for the preparation of clopidogrel and its pharmaceutically acceptable salts |
| EP1980563A1 (en) | 2007-04-09 | 2008-10-15 | BATTULA, Srinivasa Reddy | Procedure for the preparation of methyl (+)-(S)-Alpha-(O-chlorophenyl)-6,7-dihydrothieno-[3,2-C]pyridine-5(4H) acetate |
| EP2107061A1 (en) | 2008-04-02 | 2009-10-07 | Krka Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of optically enriched clopidogrel |
| US20090264460A1 (en) * | 2008-04-21 | 2009-10-22 | Mamta Mishra | Clopidogrel pharmaceutical formulations |
| KR100990949B1 (ko) | 2008-06-09 | 2010-10-29 | 엔자이텍 주식회사 | 클로피도그렐 및 그의 유도체의 제조방법 |
| US20110190502A1 (en) * | 2008-10-24 | 2011-08-04 | Sandoz Ag | Process for the preparation of s-clopidogrel |
| US8563690B2 (en) * | 2008-11-03 | 2013-10-22 | The Board Of Trustees Of The University Of Illinois | Modulation of platelet aggregation |
| CN101544655B (zh) * | 2009-05-05 | 2012-07-04 | 上海医药集团股份有限公司 | 噻吩并[3，2-c]吡啶衍生物的制备方法 |
| CN101863899B (zh) * | 2010-06-21 | 2013-03-20 | 常州制药厂有限公司 | 一种提高氯吡格雷樟脑磺酸盐拆分收率的方法 |
| KR20170004282A (ko) | 2015-07-02 | 2017-01-11 | 류종렬 | 수도 지지부가 구비된 쉐이크 핸드형 탁구 라켓 |
| KR20170004283A (ko) | 2015-07-02 | 2017-01-11 | 류종렬 | 그립부가 개선된 쉐이크 핸드형 탁구 라켓 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2530247B1 (fr) | 1982-07-13 | 1986-05-16 | Sanofi Sa | Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique |
| FR2608607B1 (fr) | 1986-12-23 | 1989-04-28 | Sanofi Sa | Procede de preparation de thienylethylamines et dithienylethylamines ainsi obtenues |
| FR2623810B2 (fr) * | 1987-02-17 | 1992-01-24 | Sanofi Sa | Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant |
| FR2652575B1 (fr) * | 1989-09-29 | 1992-01-24 | Sanofi Sa | Procede de preparation d'acides alpha-bromo phenylacetiques. |
| FR2664596B1 (fr) * | 1990-07-10 | 1994-06-10 | Sanofi Sa | Procede de preparation d'un derive n-phenylacetique de tetrahydrothieno [3,2-c] pyridine et son intermediaire de synthese. |
-
1997
- 1997-05-13 HU HU9700885A patent/HU222283B1/hu active IP Right Grant
-
1998
- 1998-05-06 HR HR980240A patent/HRP980240B1/xx not_active IP Right Cessation
- 1998-05-08 ZA ZA983921A patent/ZA983921B/xx unknown
- 1998-05-11 DE DE69803176T patent/DE69803176T2/de not_active Expired - Lifetime
- 1998-05-11 SK SK1516-99A patent/SK283700B6/sk not_active IP Right Cessation
- 1998-05-11 RS YUP-587/99A patent/RS49626B/sr unknown
- 1998-05-11 ES ES98921670T patent/ES2172141T3/es not_active Expired - Lifetime
- 1998-05-11 CZ CZ19993939A patent/CZ292820B6/cs not_active IP Right Cessation
- 1998-05-11 WO PCT/HU1998/000048 patent/WO1998051689A1/en active IP Right Grant
- 1998-05-11 DK DK98921670T patent/DK0981529T3/da active
- 1998-05-11 US US09/423,549 patent/US6180793B1/en not_active Expired - Lifetime
- 1998-05-11 CA CA002289623A patent/CA2289623C/en not_active Expired - Fee Related
- 1998-05-11 NZ NZ501577A patent/NZ501577A/en not_active IP Right Cessation
- 1998-05-11 CN CN98805036A patent/CN1109036C/zh not_active Expired - Lifetime
- 1998-05-11 EE EEP199900488A patent/EE03925B1/xx unknown
- 1998-05-11 KR KR10-1999-7010466A patent/KR100428238B1/ko not_active IP Right Cessation
- 1998-05-11 RU RU99126506/04A patent/RU2172315C1/ru active
- 1998-05-11 EP EP98921670A patent/EP0981529B1/en not_active Expired - Lifetime
- 1998-05-11 TR TR1999/02783T patent/TR199902783T2/xx unknown
- 1998-05-11 IL IL13277498A patent/IL132774A0/xx not_active IP Right Cessation
- 1998-05-11 PL PL336693A patent/PL194859B1/pl unknown
- 1998-05-11 BR BRPI9809112-3A patent/BR9809112B1/pt not_active IP Right Cessation
- 1998-05-11 AT AT98921670T patent/ATE212025T1/de active
- 1998-05-11 AU AU74448/98A patent/AU735702B2/en not_active Expired
- 1998-05-11 PT PT98921670T patent/PT981529E/pt unknown
- 1998-05-11 ME MEP-1999-587A patent/ME01636B/me unknown
- 1998-05-12 MY MYPI98002116A patent/MY121299A/en unknown
- 1998-05-12 EG EG52098A patent/EG21973A/xx active
- 1998-05-12 DZ DZ980098A patent/DZ2487A1/xx active
- 1998-05-13 CO CO98026855A patent/CO4950564A1/es unknown
- 1998-05-13 AR ARP980102220A patent/AR014349A1/es active IP Right Grant
- 1998-06-12 TW TW087109424A patent/TW552263B/zh not_active IP Right Cessation
- 1998-09-27 SA SA98190583A patent/SA98190583B1/ar unknown
- 1998-11-05 ID IDW991592A patent/ID23018A/id unknown
- 1998-11-05 UA UA99126785A patent/UA66359C2/uk unknown
-
1999
- 1999-11-11 IS IS5244A patent/IS1883B/is unknown
- 1999-11-12 NO NO19995533A patent/NO325419B1/no not_active IP Right Cessation
-
2000
- 2000-10-10 HK HK00106408A patent/HK1027350A1/xx not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PF | Patent in force | ||
| PE | Patent expired |
Effective date: 20180510 |