US5981485A
(en)
*
|
1997-07-14 |
1999-11-09 |
Genentech, Inc. |
Human growth hormone aqueous formulation
|
US5763394A
(en)
*
|
1988-04-15 |
1998-06-09 |
Genentech, Inc. |
Human growth hormone aqueous formulation
|
WO1994003198A1
(en)
*
|
1992-07-31 |
1994-02-17 |
Genentech, Inc. |
Human growth hormone aqueous formulation
|
US5374620A
(en)
*
|
1990-06-07 |
1994-12-20 |
Genentech, Inc. |
Growth-promoting composition and its use
|
US5126324A
(en)
*
|
1990-06-07 |
1992-06-30 |
Genentech, Inc. |
Method of enhancing growth in patients using combination therapy
|
US5681814A
(en)
*
|
1990-06-07 |
1997-10-28 |
Genentech, Inc. |
Formulated IGF-I Composition
|
US5210017A
(en)
*
|
1990-11-19 |
1993-05-11 |
Genentech, Inc. |
Ligand-mediated immunofunctional hormone binding protein assay method
|
US6326154B1
(en)
*
|
1990-11-19 |
2001-12-04 |
Genentech, Inc. |
Ligand-mediated immunofunctional hormone binding protein assay method
|
DE4040954C2
(de)
|
1990-12-20 |
2001-05-17 |
Max Planck Gesellschaft |
Verfahren zur Erzeugung von pathogen-resistenten Pflanzen
|
SE9201073D0
(sv)
*
|
1992-04-03 |
1992-04-03 |
Kabi Pharmacia Ab |
Protein formulation
|
US5643867A
(en)
*
|
1992-08-26 |
1997-07-01 |
Celtrix Pharmaceuticals, Inc. |
Method for treating catabolic conditions
|
US5444045A
(en)
*
|
1992-09-17 |
1995-08-22 |
Gropep, Pty. Ltd. |
Method of administering IGF-1, IGF-2, and analogs thereof to birds
|
US5273961A
(en)
*
|
1992-09-22 |
1993-12-28 |
Genentech, Inc. |
Method of prophylaxis of acute renal failure
|
ES2095086T3
(es)
*
|
1992-10-29 |
1997-02-01 |
Genentech Inc |
Metodo para el tratamiento y la prevencion de la obesidad.
|
SE9300105D0
(sv)
*
|
1993-01-15 |
1993-01-15 |
Kabi Pharmacia Ab |
Stable protein solution
|
SE9301667D0
(sv)
*
|
1993-05-14 |
1993-05-14 |
Kabi Pharmacia Ab |
New use
|
WO1995002411A1
(en)
*
|
1993-07-16 |
1995-01-26 |
Mallinckrodt Veterinary Limited |
Stabilised polypeptide growth factor formulation at low ph
|
US6046222A
(en)
*
|
1993-09-15 |
2000-04-04 |
Warner-Lambert Company |
Use of thiazolidinedione derivatives in the treatment of polycystic ovary syndrome, gestational diabetes and disease states at risk for progressing to noninsulin-dependent diabetes mellitus
|
US20020049422A1
(en)
*
|
1994-03-31 |
2002-04-25 |
Brewitt Barbara A. |
Homeopathic preparations
|
US6239105B1
(en)
*
|
1994-03-31 |
2001-05-29 |
Barbara A. Brewitt |
Homeopathic preparations of purified growth hormone
|
US5824642A
(en)
*
|
1994-04-07 |
1998-10-20 |
Genentech, Inc. |
Treatment of partial growth hormone insensitivity syndrome
|
US6207640B1
(en)
*
|
1994-04-07 |
2001-03-27 |
Genentech, Inc. |
Treatment of partial growth hormone insensitivity syndrome
|
US5646113A
(en)
*
|
1994-04-07 |
1997-07-08 |
Genentech, Inc. |
Treatment of partial growth hormone insensitivity syndrome
|
US5661122A
(en)
*
|
1994-04-15 |
1997-08-26 |
Genentech, Inc. |
Treatment of congestive heart failure
|
US5610134A
(en)
*
|
1994-04-15 |
1997-03-11 |
Genentech, Inc. |
Treatment of congestive heart failure
|
US5444047A
(en)
*
|
1994-06-16 |
1995-08-22 |
Dipasquale; Gene |
Treatment of arthritic and post-surgical orthopedic conditions with Insulin-like Growth Factor-I
|
EP0776213A1
(de)
*
|
1994-09-21 |
1997-06-04 |
Pharmacia & Upjohn Aktiebolag |
Verfahren für die behandlung von hypertonie in trächtigen säugetieren
|
US5824784A
(en)
*
|
1994-10-12 |
1998-10-20 |
Amgen Inc. |
N-terminally chemically modified protein compositions and methods
|
AU693478B2
(en)
*
|
1994-11-10 |
1998-07-02 |
Metabolic Pharmaceuticals Limited |
Treatment of obesity
|
US20020142965A1
(en)
*
|
1994-11-15 |
2002-10-03 |
Metabolic Pharmaceuticals, Ltd. |
Treatment of obesity
|
US6335319B1
(en)
|
1994-11-15 |
2002-01-01 |
Metabolic Pharmaceuticals, Inc. |
Treatment of obesity
|
US5858966A
(en)
*
|
1994-12-21 |
1999-01-12 |
Auckland Uniservices Limited |
Fetal growth
|
ZA96122B
(en)
*
|
1995-01-13 |
1996-07-24 |
Novo Nordisk As |
A pharmaceutical formulation
|
EP0805689A1
(de)
*
|
1995-01-13 |
1997-11-12 |
Novo Nordisk A/S |
Stabilisierte pharmazeutische zubereitung, welche ein wachstumshormon und x-lys enthält
|
US5705482A
(en)
*
|
1995-01-13 |
1998-01-06 |
Novo Nordisk A/S |
Pharmaceutical formulation
|
SE9501472D0
(sv)
*
|
1995-04-21 |
1995-04-21 |
Pharmacia Ab |
Truncated IGF-I
|
US5741776A
(en)
*
|
1995-05-22 |
1998-04-21 |
Genentech, Inc. |
Method of administration of IGF-I
|
US5565428A
(en)
*
|
1995-05-22 |
1996-10-15 |
Genentech, Inc. |
Method of administration of IGF-I
|
ES2163020T3
(es)
*
|
1995-05-26 |
2002-01-16 |
Theratechnologies Inc |
Analogos quimericos de factor liberador de hormona de crecimiento (grf) de cuerpo graso, provistos de mayor potencia biologica.
|
EP0766966A3
(de)
*
|
1995-09-08 |
2001-02-28 |
Eli Lilly And Company |
Methode zur Behandlung der Insulinresistenz
|
JPH10508322A
(ja)
|
1995-10-12 |
1998-08-18 |
スーパーゲン,インコーポレイティド |
5βステロイドのリポソーム配合物
|
AUPN801296A0
(en)
*
|
1996-02-12 |
1996-03-07 |
Csl Limited |
Stabilised growth hormone formulation and method of preparation thereof
|
US5948757A
(en)
*
|
1996-03-01 |
1999-09-07 |
Celtrix Pharmaceuticals, Inc. |
High dose IGF-1 therapy
|
AU2334097A
(en)
*
|
1996-03-21 |
1997-10-10 |
Merck & Co., Inc. |
4-spiroindoline piperidines promote release of growth hormone
|
US20070179096A1
(en)
*
|
1996-04-24 |
2007-08-02 |
Novo Nordisk A/S |
Pharmaceutical Formulation
|
US5783556A
(en)
*
|
1996-08-13 |
1998-07-21 |
Genentech, Inc. |
Formulated insulin-containing composition
|
EP0920518A1
(de)
*
|
1996-08-26 |
1999-06-09 |
Signal Pharmaceuticals, Inc. |
Von einem stimulus induzierbarer i(kappa)b kinase komplex
|
US5855920A
(en)
*
|
1996-12-13 |
1999-01-05 |
Chein; Edmund Y. M. |
Total hormone replacement therapy
|
ZA9711731B
(en)
*
|
1996-12-31 |
1998-07-01 |
Monsanto Co |
Aqueous glycerol formulations of somatotropin
|
FR2758460B1
(fr)
*
|
1997-01-21 |
1999-12-31 |
Sanofi Sa |
Utilisation des agonistes des recepteurs beta-3 adrenergiques pour la preparation de medicaments cicatrisants
|
US6004932A
(en)
*
|
1997-03-06 |
1999-12-21 |
Iowa State University Research Foundation, Inc. |
Use of glucagon as a metabolic conditioner for dairy cows and other ruminants
|
US6121416A
(en)
|
1997-04-04 |
2000-09-19 |
Genentech, Inc. |
Insulin-like growth factor agonist molecules
|
US6420518B1
(en)
|
1997-04-04 |
2002-07-16 |
Genetech, Inc. |
Insulin-like growth factor agonist molecules
|
US5866546A
(en)
*
|
1997-04-18 |
1999-02-02 |
Hadasit Medical Research Services And Development Company Ltd. |
Treatment for diabetes
|
US5840042A
(en)
*
|
1997-05-16 |
1998-11-24 |
St. Luke's-Roosevelt Hospital |
Method of predicting body composition in prepubertal children infected with human immunodenficiency virus
|
RU2223970C2
(ru)
*
|
1997-09-08 |
2004-02-20 |
Метаболик Фармасьютикалз Лтд. |
Лечение ожирения
|
WO1999024061A1
(en)
|
1997-11-07 |
1999-05-20 |
Chiron Corporation |
Method for producing igf-1 sustained-release formulations
|
US6767892B1
(en)
*
|
1997-11-07 |
2004-07-27 |
Chrion Corporation |
Compositions providing for increased IGF-I solubility
|
SE9704405D0
(sv)
*
|
1997-11-28 |
1997-11-28 |
Pharmacia & Upjohn Ab |
New syringe
|
AU3473999A
(en)
*
|
1998-04-03 |
1999-10-25 |
Chiron Corporation |
Injectable igf-formulations containing succinate as buffering agent
|
US6013622A
(en)
*
|
1998-04-15 |
2000-01-11 |
Nutriceutical Technology Corporation |
Method of regulating appetite and metabolism
|
AU779893B2
(en)
*
|
1998-12-10 |
2005-02-17 |
Signal Pharmaceuticals, Llc |
Human ubiquitin ligase E3 for the modulation of NF-Kappa B
|
US6696063B1
(en)
*
|
1998-12-30 |
2004-02-24 |
Applied Research Systems Ars Holding N.V. |
Treatment of HIV-associated dysmorphia/dysmetabolic syndrome (HADDS) with or without lipodystrophy
|
AU762351B2
(en)
*
|
1999-01-06 |
2003-06-26 |
Genentech Inc. |
Insulin-like growth factor (IGF) I mutant variants
|
ATE251466T1
(de)
|
1999-04-08 |
2003-10-15 |
Genentech Inc |
Zusammensetzung auf basis gegensätzlich geladener polypeptide
|
CZ200260A3
(cs)
*
|
1999-07-12 |
2002-04-17 |
Grandis Biotech Gmbh |
Formulace růstového hormonu
|
US6521266B1
(en)
*
|
1999-09-23 |
2003-02-18 |
Morris A. Mann |
Composition for growth hormone production and release, appetite suppression, and methods related thereto
|
WO2001032200A1
(en)
*
|
1999-11-03 |
2001-05-10 |
Novo Nordisk A/S |
Use of a growth hormone or a growth hormone secretagogue for appetite-suppression or induction of satiety
|
WO2001054695A1
(en)
*
|
2000-01-31 |
2001-08-02 |
The University Of Kentucky Research Foundation |
Triazines as appetite suppressor
|
ES2301547T3
(es)
*
|
2000-05-16 |
2008-07-01 |
Genentech, Inc. |
Tratamiento de trastornos del cartilago.
|
CA2380423A1
(en)
*
|
2000-05-17 |
2001-11-22 |
Bionebraska, Inc. |
Peptide pharmaceutical formulations
|
US6946243B2
(en)
*
|
2000-07-20 |
2005-09-20 |
Solvay Pharmaceuticals Gmbh |
Method of identifying compounds suitable for treatment and/or prophylaxis of obesity
|
DE10035227A1
(de)
*
|
2000-07-20 |
2002-01-31 |
Solvay Pharm Gmbh |
Verfahren zum Auffinden von Verbindungen, welche zur Behandlung und/oder Prophylaxe von Fettleibigkeit geeignet sind
|
US20060159724A1
(en)
*
|
2000-08-08 |
2006-07-20 |
Bell Stacey J |
Nutritional supplement for the management of weight
|
US7493171B1
(en)
|
2000-11-21 |
2009-02-17 |
Boston Scientific Neuromodulation Corp. |
Treatment of pathologic craving and aversion syndromes and eating disorders by electrical brain stimulation and/or drug infusion
|
US6832114B1
(en)
|
2000-11-21 |
2004-12-14 |
Advanced Bionics Corporation |
Systems and methods for modulation of pancreatic endocrine secretion and treatment of diabetes
|
US6950707B2
(en)
|
2000-11-21 |
2005-09-27 |
Advanced Bionics Corporation |
Systems and methods for treatment of obesity and eating disorders by electrical brain stimulation and/or drug infusion
|
US7440806B1
(en)
|
2000-11-21 |
2008-10-21 |
Boston Scientific Neuromodulation Corp. |
Systems and methods for treatment of diabetes by electrical brain stimulation and/or drug infusion
|
US6922590B1
(en)
|
2000-11-21 |
2005-07-26 |
Advanced Bionics Corporation |
Systems and methods for treatment of diabetes by electrical brain stimulation and/or drug infusion
|
US7118873B2
(en)
|
2000-12-12 |
2006-10-10 |
The University Of Connecticut |
Polynucleotides encoding cellular transporters and methods of use thereof
|
US20030082647A1
(en)
*
|
2000-12-12 |
2003-05-01 |
Reenan Robert A. |
Transporter protein
|
WO2002058724A2
(en)
*
|
2001-01-26 |
2002-08-01 |
Eli Lilly And Company |
Use of lp82 to treat body weight disorders
|
EP1772464B1
(de)
*
|
2001-02-09 |
2009-08-12 |
Genentech, Inc. |
Verfahren zur Identifizierung von indirekten IGF-1-Agonisten
|
US7060675B2
(en)
|
2001-02-15 |
2006-06-13 |
Nobex Corporation |
Methods of treating diabetes mellitus
|
GB0112363D0
(en)
|
2001-05-21 |
2001-07-11 |
Allied Therapeutics Ltd |
Method and apparatus for treating biological fluids
|
US6713452B2
(en)
|
2001-06-04 |
2004-03-30 |
Nobex Corporation |
Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US6828297B2
(en)
*
|
2001-06-04 |
2004-12-07 |
Nobex Corporation |
Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US7713932B2
(en)
|
2001-06-04 |
2010-05-11 |
Biocon Limited |
Calcitonin drug-oligomer conjugates, and uses thereof
|
US6835802B2
(en)
*
|
2001-06-04 |
2004-12-28 |
Nobex Corporation |
Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
|
US6858580B2
(en)
*
|
2001-06-04 |
2005-02-22 |
Nobex Corporation |
Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US6828305B2
(en)
|
2001-06-04 |
2004-12-07 |
Nobex Corporation |
Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
|
US20030072761A1
(en)
*
|
2001-10-16 |
2003-04-17 |
Lebowitz Jonathan |
Methods and compositions for targeting proteins across the blood brain barrier
|
US20040162237A1
(en)
*
|
2002-01-15 |
2004-08-19 |
Fox Niles Wayne |
Use of lp82 to treat body weight disorders
|
CA2478183C
(en)
*
|
2002-03-12 |
2010-02-16 |
Merck & Co. Inc. |
Substituted amides
|
AU2003236521A1
(en)
|
2002-06-13 |
2003-12-31 |
Nobex Corporation |
Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus
|
US20040122033A1
(en)
*
|
2002-12-10 |
2004-06-24 |
Nargund Ravi P. |
Combination therapy for the treatment of obesity
|
US8519008B2
(en)
|
2003-01-22 |
2013-08-27 |
Purina Animal Nutrition Llc |
Method and composition for improving the health of young monogastric mammals
|
JP5108303B2
(ja)
*
|
2003-08-21 |
2012-12-26 |
テルシカ インコーポレーティッド |
インスリン様成長因子(igf−i)のレベル上昇による内臓脂肪の低下方法
|
EP1667521B1
(de)
*
|
2003-09-12 |
2011-12-07 |
Tercica, Inc. |
Verfahren zur behandlung von igf-1 (insulin-like growth factor 1)-mangel
|
US8147561B2
(en)
|
2004-02-26 |
2012-04-03 |
Endosphere, Inc. |
Methods and devices to curb appetite and/or reduce food intake
|
US8585771B2
(en)
|
2004-02-26 |
2013-11-19 |
Endosphere, Inc. |
Methods and devices to curb appetite and/or to reduce food intake
|
US7931693B2
(en)
*
|
2004-02-26 |
2011-04-26 |
Endosphere, Inc. |
Method and apparatus for reducing obesity
|
EP1591114A1
(de)
*
|
2004-03-12 |
2005-11-02 |
Fournier Laboratories Ireland Limited |
Verwendung von Metformin und Orlistat zur Behandlung oder Vorbeugung von Obesität
|
EP2626368B1
(de)
|
2004-07-19 |
2016-12-21 |
Biocon Limited |
Insulinoligomerkonjugate, Formulierungen und Verwendungen davon
|
NZ553057A
(en)
*
|
2004-08-30 |
2009-12-24 |
Tercica Inc |
Method and device for diagnosing and treating insulin-like growth factor deficiency disorders
|
US8158582B2
(en)
*
|
2005-06-02 |
2012-04-17 |
Tercica, Inc. |
Methods for treatment of insulin-like growth factor-1 deficiency
|
US10351615B2
(en)
|
2006-02-03 |
2019-07-16 |
Opko Biologics Ltd. |
Methods of treatment with long-acting growth hormone
|
US8946155B2
(en)
|
2006-02-03 |
2015-02-03 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
US20150038413A1
(en)
|
2006-02-03 |
2015-02-05 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
US8759292B2
(en)
|
2006-02-03 |
2014-06-24 |
Prolor Biotech, Llc |
Long-acting coagulation factors and methods of producing same
|
US7553941B2
(en)
|
2006-02-03 |
2009-06-30 |
Modigene Inc |
Long-acting polypeptides and methods of producing same
|
US9249407B2
(en)
|
2006-02-03 |
2016-02-02 |
Opko Biologics Ltd. |
Long-acting coagulation factors and methods of producing same
|
US8048849B2
(en)
|
2006-02-03 |
2011-11-01 |
Modigene, Inc. |
Long-acting polypeptides and methods of producing same
|
US8476234B2
(en)
*
|
2006-02-03 |
2013-07-02 |
Prolor Biotech Inc. |
Long-acting coagulation factors and methods of producing same
|
US20140113860A1
(en)
|
2006-02-03 |
2014-04-24 |
Prolor Biotech Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
US10221228B2
(en)
|
2006-02-03 |
2019-03-05 |
Opko Biologics Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
US9458444B2
(en)
|
2006-02-03 |
2016-10-04 |
Opko Biologics Ltd. |
Long-acting coagulation factors and methods of producing same
|
US8450269B2
(en)
*
|
2006-02-03 |
2013-05-28 |
Prolor Biotech Ltd. |
Long-acting growth hormone and methods of producing same
|
US9060835B2
(en)
*
|
2006-05-26 |
2015-06-23 |
Endosphere, Inc. |
Conformationally-stabilized intraluminal device for medical applications
|
US8748419B2
(en)
*
|
2006-06-16 |
2014-06-10 |
Theracos, Inc. |
Treating obesity with muscarinic receptor M1 antagonists
|
US20080220104A1
(en)
*
|
2007-03-08 |
2008-09-11 |
Cappello John V |
Compositions for producing satiety
|
US20110137227A1
(en)
*
|
2007-07-16 |
2011-06-09 |
Mckinley James T |
Methods and devices for delivering or delaying lipids within a duodenum
|
RU2453332C2
(ru)
*
|
2007-10-16 |
2012-06-20 |
Байокон Лимитид |
Твердая фармацевтическая композиция (варианты) и способ контроля концентрации глюкозы с ее помощью, способ получения твердой фармацевтической композиции (варианты), таблетка (варианты) и способ получения амфорных частиц
|
US8986253B2
(en)
|
2008-01-25 |
2015-03-24 |
Tandem Diabetes Care, Inc. |
Two chamber pumps and related methods
|
US8408421B2
(en)
|
2008-09-16 |
2013-04-02 |
Tandem Diabetes Care, Inc. |
Flow regulating stopcocks and related methods
|
WO2010033878A2
(en)
|
2008-09-19 |
2010-03-25 |
David Brown |
Solute concentration measurement device and related methods
|
US9663778B2
(en)
|
2009-07-09 |
2017-05-30 |
OPKO Biologies Ltd. |
Long-acting coagulation factors and methods of producing same
|
EP3284494A1
(de)
|
2009-07-30 |
2018-02-21 |
Tandem Diabetes Care, Inc. |
Tragbares infusionspumpensystem
|
CA2780554C
(en)
*
|
2009-11-17 |
2017-08-15 |
Ipsen Pharma S.A.S. |
Formulation for hgh and rhigf-1 combination
|
US20110152188A1
(en)
*
|
2009-12-23 |
2011-06-23 |
Hanns-Christian Mahler |
Pharmaceutical compositions of igf/i proteins
|
MY167814A
(en)
|
2012-04-19 |
2018-09-26 |
Opko Biologics Ltd |
Long-acting oxyntomodulin variants and methods of producing same
|
US9180242B2
(en)
|
2012-05-17 |
2015-11-10 |
Tandem Diabetes Care, Inc. |
Methods and devices for multiple fluid transfer
|
BR122020018510B1
(pt)
|
2012-11-20 |
2023-03-14 |
Opko Biologics Ltd |
Método para aumentar incrementalmente o tamanho hidrodinâmico de um fator de coagulação ativado viia
|
US9173998B2
(en)
|
2013-03-14 |
2015-11-03 |
Tandem Diabetes Care, Inc. |
System and method for detecting occlusions in an infusion pump
|
US20150158926A1
(en)
|
2013-10-21 |
2015-06-11 |
Opko Biologics, Ltd. |
Long-acting polypeptides and methods of producing and administering same
|
ES2893616T3
(es)
|
2015-06-19 |
2022-02-09 |
Opko Biologics Ltd |
Factores de coagulación de acción prolongada y métodos para la producción de los mismos
|
AU2017296352A1
(en)
|
2016-07-11 |
2019-02-21 |
Opko Biologics Ltd. |
Long-acting coagulation factor VII and methods of producing same
|
KR102245539B1
(ko)
|
2018-02-12 |
2021-04-29 |
주식회사 지앤피바이오사이언스 |
코어-쉘 구조의 마이크로 입자를 유효성분으로 포함하는 성장인자 유전자 발현 증가용 조성물
|
KR20210024082A
(ko)
|
2018-06-25 |
2021-03-04 |
제이씨알 파마 가부시키가이샤 |
단백질 함유 수성 액제
|