GR880100507A - 1,4-διυδροπυριδινες μεθοδος παρασκευης τους και εφαρμογη τους ως φαρμακα - Google Patents
1,4-διυδροπυριδινες μεθοδος παρασκευης τους και εφαρμογη τους ως φαρμακαInfo
- Publication number
- GR880100507A GR880100507A GR880100507A GR880100507A GR880100507A GR 880100507 A GR880100507 A GR 880100507A GR 880100507 A GR880100507 A GR 880100507A GR 880100507 A GR880100507 A GR 880100507A GR 880100507 A GR880100507 A GR 880100507A
- Authority
- GR
- Greece
- Prior art keywords
- dihydropyridines
- asmedicines
- preparation process
- application therefor
- therefor
- Prior art date
Links
- YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical class C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP87401799A EP0302980B1 (fr) | 1987-08-03 | 1987-08-03 | 1,4-Dihydropyridines, leur procédé de préparation et leur application comme médicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR880100507A true GR880100507A (el) | 1989-05-25 |
Family
ID=8198243
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR880100507A GR880100507A (el) | 1987-08-03 | 1988-08-02 | 1,4-διυδροπυριδινες μεθοδος παρασκευης τους και εφαρμογη τους ως φαρμακα |
| GR91400660T GR3001984T3 (en) | 1987-08-03 | 1991-05-22 | 1,4-dihydropyridines, process for their preparation and their use as medicaments |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR91400660T GR3001984T3 (en) | 1987-08-03 | 1991-05-22 | 1,4-dihydropyridines, process for their preparation and their use as medicaments |
Country Status (34)
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5242933A (en) * | 1990-07-10 | 1993-09-07 | Adir Et Compagnie | Piperidine, tetrahydropyridine and pyrrolidine compounds |
| WO1997004781A1 (en) * | 1995-08-02 | 1997-02-13 | Smithkline Beecham Corporation | Endothelin receptor antagonists |
| RU2168987C2 (ru) * | 1997-04-15 | 2001-06-20 | Санкт-Петербургская Государственная Химико-Фармацевтическая Академия | Гипотензивное средство |
| RU2155036C2 (ru) * | 1998-11-11 | 2000-08-27 | Азад Зияд Оглы Абышев | Средство для лечения ишемической болезни сердца |
| IT1304513B1 (it) * | 1998-12-30 | 2001-03-19 | Endura Spa | Processo per la sintesi di 5-(alfa-idrossialchil)benzo(1,3)diossoli. |
| RU2239432C2 (ru) * | 2000-04-11 | 2004-11-10 | Санкио Компани Лимитед, Убе Индастриз, Лтд. | Стабилизированная фармацевтическая композиция, содержащая блокатор кальция |
| RU2187303C2 (ru) * | 2000-10-12 | 2002-08-20 | Азад Зияд Оглы Абышев | Способ получения таблеток диуманкала - forte по 0,01 г |
| MXPA05001958A (es) | 2002-08-19 | 2005-04-28 | Pfizer Prod Inc | Terapia de combinacion para enfermedades hiperproliferativas. |
| WO2006014930A2 (en) * | 2004-07-26 | 2006-02-09 | Cotherix, Inc. | Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation |
| US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| EP2351569B1 (en) | 2005-10-26 | 2012-08-22 | Asahi Kasei Pharma Corporation | Fasudil in combination therapies for the treatment of pulmonary arterial hypertension |
| ATE551059T1 (de) | 2005-10-26 | 2012-04-15 | Asahi Kasei Pharma Corp | Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| TW200806648A (en) * | 2005-11-29 | 2008-02-01 | Sankyo Co | Acid addition salts of dihydropyridine derivatives |
| TW200736245A (en) * | 2005-11-29 | 2007-10-01 | Sankyo Co | Acid addition salts of optically active dihydropyridine derivatives |
| US7919506B2 (en) | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
| ATE547394T1 (de) | 2006-12-01 | 2012-03-15 | Bristol Myers Squibb Co | N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen |
| US8883844B2 (en) | 2010-09-24 | 2014-11-11 | Nitrogenix Inc. | Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions |
| CN105143203A (zh) | 2013-04-17 | 2015-12-09 | 辉瑞大药厂 | 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物 |
| WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
| JOP20210193A1 (ar) | 2019-01-18 | 2023-01-30 | Astrazeneca Ab | مثبطات pcsk9 وطرق استخدامها |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0158211A2 (fr) * | 1984-03-27 | 1985-10-16 | Laboratorios Delagrange S.A. | Nouveaux dérivés de 1,4 dihydropyridine, leur procédé de préparation, et leur application comme médicaments |
| EP0174131A2 (en) * | 1984-09-01 | 1986-03-12 | FISONS plc | Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3441648A (en) * | 1967-02-07 | 1969-04-29 | Smithkline Corp | Compositions and methods for lowering blood pressure with 1,4-dihydropyridines |
| US4031104A (en) * | 1972-04-18 | 1977-06-21 | Bayer Aktiengesellschaft | 1,4-Dihydropyridine carboxylic acid esters |
| JPS5978186A (ja) * | 1982-10-27 | 1984-05-04 | Yoshitomi Pharmaceut Ind Ltd | １，４−ジヒドロピリジン−３，５−ジカルボン酸エステル誘導体 |
| ES531033A0 (es) * | 1984-03-27 | 1985-09-01 | Inst Investigacion Desarrollo | Un procedimiento para la preparacion de nuevas 1,4-dihidropirinas-4-(polioxialquilfenil)-sustituidas |
| JPH068294B2 (ja) * | 1985-02-26 | 1994-02-02 | 富山化学工業株式会社 | 新規な１，４−ジヒドロピリジン誘導体およびその塩 |
| JPH01207267A (ja) * | 1987-03-05 | 1989-08-21 | Yamanouchi Pharmaceut Co Ltd | ピリジン誘導体及び該化合物を含有する肝疾患治療剤 |
-
1987
- 1987-08-03 DE DE8787401799T patent/DE3768658D1/de not_active Expired - Lifetime
- 1987-08-03 EP EP87401799A patent/EP0302980B1/fr not_active Expired - Lifetime
- 1987-08-03 AT AT87401799T patent/ATE61588T1/de active
-
1988
- 1988-07-27 LU LU87297A patent/LU87297A1/fr unknown
- 1988-07-29 YU YU147088A patent/YU46547B/sh unknown
- 1988-07-29 DE DE3825962A patent/DE3825962A1/de not_active Withdrawn
- 1988-07-29 CA CA000573422A patent/CA1306261C/fr not_active Expired - Lifetime
- 1988-08-01 JP JP63192591A patent/JPH0733383B2/ja not_active Expired - Lifetime
- 1988-08-01 FI FI883603A patent/FI91406C/fi not_active IP Right Cessation
- 1988-08-01 MA MA21587A patent/MA21344A1/fr unknown
- 1988-08-01 DD DD88318537A patent/DD282008A5/de not_active IP Right Cessation
- 1988-08-01 NO NO883406A patent/NO170934C/no unknown
- 1988-08-02 GB GB8818356A patent/GB2208861B/en not_active Expired - Lifetime
- 1988-08-02 TN TNTNSN88081A patent/TNSN88081A1/fr unknown
- 1988-08-02 GR GR880100507A patent/GR880100507A/el unknown
- 1988-08-02 IT IT8848259A patent/IT1235013B/it active
- 1988-08-02 SK SK5413-88A patent/SK278775B6/sk unknown
- 1988-08-02 IL IL87321A patent/IL87321A/xx not_active IP Right Cessation
- 1988-08-02 ES ES8802413A patent/ES2007543A6/es not_active Expired
- 1988-08-02 DK DK430288A patent/DK430288A/da not_active Application Discontinuation
- 1988-08-02 BE BE8800893A patent/BE1001055A4/fr not_active IP Right Cessation
- 1988-08-02 KR KR1019880009867A patent/KR960001724B1/ko not_active Expired - Fee Related
- 1988-08-02 CZ CS885413A patent/CZ282077B6/cs not_active IP Right Cessation
- 1988-08-02 PT PT88173A patent/PT88173B/pt not_active IP Right Cessation
- 1988-08-02 HU HU884065A patent/HU204523B/hu not_active IP Right Cessation
- 1988-08-02 CH CH2922/88A patent/CH675999A5/fr not_active IP Right Cessation
- 1988-08-02 CN CN88106537A patent/CN1038587C/zh not_active Expired - Fee Related
- 1988-08-02 IE IE236488A patent/IE60358B1/en not_active IP Right Cessation
- 1988-08-02 IS IS3378A patent/IS1549B/is unknown
- 1988-08-02 US US07/227,373 patent/US4952592A/en not_active Expired - Fee Related
- 1988-08-02 NZ NZ225661A patent/NZ225661A/xx unknown
- 1988-08-03 ZA ZA885684A patent/ZA885684B/xx unknown
- 1988-08-03 IN IN556/MAS/88A patent/IN167550B/en unknown
- 1988-08-03 PH PH37337A patent/PH25645A/en unknown
-
1990
- 1990-08-28 CA CA000615848A patent/CA1306262C/fr not_active Expired - Lifetime
-
1991
- 1991-05-22 GR GR91400660T patent/GR3001984T3/el unknown
-
1992
- 1992-03-31 RU SU925011204A patent/RU2036922C1/ru active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0158211A2 (fr) * | 1984-03-27 | 1985-10-16 | Laboratorios Delagrange S.A. | Nouveaux dérivés de 1,4 dihydropyridine, leur procédé de préparation, et leur application comme médicaments |
| EP0174131A2 (en) * | 1984-09-01 | 1986-03-12 | FISONS plc | Dihydropyridines, processes and intermediates for their production, and pharmaceutical formulations containing them |
Non-Patent Citations (2)
| Title |
|---|
| CHEMICAL ABSTRACTS, vol. 105, 1986, page 731, abstract no. 172299g, Columbus, Ohio, US; & ES-A-536 537 (INSTITUTO DE INVESTIGACION Y DESARROLLO QUIMICO Y BIOLOGICO S.A.) 01-08-1985 * |
| CLAIMS SEARCHED: ALL * |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GR880100507A (el) | 1,4-διυδροπυριδινες μεθοδος παρασκευης τους και εφαρμογη τους ως φαρμακα | |
| GR880100346A (el) | Μεθοδος βαφης κερατινικων ινων με βασεις οξειδωσεως συνδιαζομενες με ιωδιουχο αλας, βαφικη συνθεση & διαταξη που χρησιμοποιειται | |
| DE3583779D1 (de) | Gelzusammensetzungen von liposomen. | |
| GR900100614A (el) | Μακροκυκλικες νοσοκατασταλτικες ενωσεις. | |
| FI875395A0 (fi) | Substituerade basiska 2-aminotetraliner. | |
| GR900100380A (el) | Μέ?οδος παρασκευής αντι-φλεγμονωδών παραγώγων αμινοφενόλης. | |
| BG38487A3 (en) | Method for preparing peptides | |
| FI884387A7 (fi) | Uudentyyppiset geelikoosteet. | |
| DE3869007D1 (de) | Oxydation von alkanen. | |
| ATE60694T1 (de) | Plasmabrenner. | |
| DE3788846D1 (de) | 1-substituierte laktame enthaltende zusammensetzungen. | |
| NO870212D0 (no) | Fremgangsmaate for fremstilling av stabile nikorandilpreparater. | |
| GR1000631B (el) | Μεθοδος παρασκευης υποκατεστημενων βενζαμιδιων φαρμακολογικως δραστικων. | |
| BG40963A3 (en) | Method for preparing 1, 3- disubstituted 2- oxyindols | |
| DE3877594D1 (de) | Gaserzeugende zusammensetzung. | |
| FI884883A7 (fi) | Ny process. | |
| GR1000460B (el) | Μεθοδος παρασκευης παραγωγων καψαικινης. | |
| ATE41773T1 (de) | 4,5-dihydro-4-oxo-2((2-transphenylcyclopropyl)amino>-3-furancarbonsaeuren und derivate davon. | |
| DE3778614D1 (de) | Hochfrequenz lichtbogenstabilisator. | |
| ATE46518T1 (de) | Sialosylcerebroside und verfahren zu ihrer herstellung. | |
| DE3875986D1 (de) | Zusammenstellung von dialysatorfasern. | |
| IT1216560B (it) | Procedimento per la preparazione di bis(2,2,6,6_tetrametil_4_piperidil)ammina. | |
| DK556885D0 (da) | Fremstilling af substituerede og usubstituerede 2-carbamoyl-nicotin- og 3-quinolincarboxylsyrer | |
| NO885566D0 (no) | Fremgangsmaate for fremstilling av poroese elektroder. | |
| BG90414A (bg) | 2-азабицикло (2,2,1)-хепт-5- ен-2-оцетна киселина и нейни производни, метод за получаване и приложението им |