GR862546B - Flavone derivatives - Google Patents

Flavone derivatives

Info

Publication number
GR862546B
GR862546B GR862546A GR860102546A GR862546B GR 862546 B GR862546 B GR 862546B GR 862546 A GR862546 A GR 862546A GR 860102546 A GR860102546 A GR 860102546A GR 862546 B GR862546 B GR 862546B
Authority
GR
Greece
Prior art keywords
flavone derivatives
flavone
derivatives
Prior art date
Application number
GR862546A
Other languages
English (en)
Inventor
Leonardi Amedeo
Pennini Renzo
Cazzulani Pietro
Dante Nardi
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Publication of GR862546B publication Critical patent/GR862546B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
GR862546A 1985-10-22 1986-10-14 Flavone derivatives GR862546B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22578/85A IT1190405B (it) 1985-10-22 1985-10-22 Derivati del flavone

Publications (1)

Publication Number Publication Date
GR862546B true GR862546B (en) 1987-03-04

Family

ID=11198039

Family Applications (1)

Application Number Title Priority Date Filing Date
GR862546A GR862546B (en) 1985-10-22 1986-10-14 Flavone derivatives

Country Status (26)

Country Link
US (1) US4806534A (el)
EP (1) EP0223744B1 (el)
JP (1) JPH0772186B2 (el)
KR (1) KR910009269B1 (el)
CN (1) CN86107544A (el)
AR (1) AR243883A1 (el)
AT (1) ATE73453T1 (el)
AU (1) AU596382B2 (el)
CA (1) CA1330994C (el)
DE (1) DE3684244D1 (el)
DK (1) DK169408B1 (el)
EG (1) EG18109A (el)
ES (1) ES2002425A6 (el)
FI (1) FI89167C (el)
GR (1) GR862546B (el)
HU (1) HU202863B (el)
IE (1) IE58330B1 (el)
IL (1) IL80229A0 (el)
IT (1) IT1190405B (el)
NO (1) NO167570C (el)
NZ (1) NZ217964A (el)
PH (1) PH22766A (el)
PT (1) PT83604B (el)
SG (1) SG55192G (el)
TN (1) TNSN86144A1 (el)
ZA (1) ZA867941B (el)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4912223A (en) * 1988-01-28 1990-03-27 Nelson Research & Development Co. 1,4-Dihydropyridines
US5580751A (en) * 1990-09-14 1996-12-03 Carlsberg A/S Process for the preparation of C-terminally amidated peptides
US5244602A (en) * 1990-12-03 1993-09-14 Ppg Industries, Inc. Photochromic naphthopyrans
DE4321030A1 (de) * 1993-06-24 1995-01-05 Bayer Ag 4-bicyclisch substituierte Dihydropyridine, Verfahren zu ihrer Herstellung und ihre Verwendung in Arzneimittel
SE9703377D0 (sv) * 1997-09-18 1997-09-18 Astra Ab New compounds
KR100392468B1 (ko) * 2000-09-18 2003-07-22 주식회사 엘지생명과학 사이클린 의존 키나아제의 저해제로서 유용한3-히드록시크로멘-4-온 유도체
IL156595A0 (en) 2001-01-16 2004-01-04 Astrazeneca Ab Therapeutic heterocyclic compounds
DE102005034264A1 (de) 2005-07-22 2007-02-01 Bayer Healthcare Ag 4-Chromenonyl-1,4-dihydropyridincarbonitrile und ihre Verwendung
DE102005034267A1 (de) 2005-07-22 2007-01-25 Bayer Healthcare Ag 4-Chromenonyl-1,4-dihydropyridine und ihre Verwendung
CN103254122B (zh) * 2013-06-19 2015-04-22 湖南师范大学 一种心血管药物尼伐地平的制备方法
AR121719A1 (es) 2020-04-03 2022-06-29 Petra Pharma Corp Inhibidores alostéricos de cromenona del fosfoinosítido 3-quinasa (pi3k) para el tratamiento de enfermedades
KR20240004865A (ko) 2021-05-03 2024-01-11 페트라 파마 코포레이션 질환의 치료를 위한 포스포이노시티드 3-키나제 (pi3k)의 알로스테릭 크로메논 억제제
EP4347040A1 (en) 2021-05-27 2024-04-10 Petra Pharma Corporation Allosteric chromenone inhibitors of phosphoinositide 3-kinase (pi3k) for the treatment of cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2921070A (en) * 1957-11-05 1960-01-12 Recordati Lab Farmacologico S Basic esters of 3-methylflavone-8-carboxylic acid
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3311005A1 (de) * 1983-03-25 1984-09-27 Bayer Ag, 5090 Leverkusen Chromon- und thiochromonsubstituierte 1,4-dihydropyridinderivate, mehrere verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln

Also Published As

Publication number Publication date
DK506386D0 (da) 1986-10-22
EP0223744B1 (en) 1992-03-11
NO167570C (no) 1991-11-20
DK169408B1 (da) 1994-10-24
TNSN86144A1 (fr) 1990-01-01
FI89167B (fi) 1993-05-14
JPH0772186B2 (ja) 1995-08-02
DE3684244D1 (de) 1992-04-16
IT1190405B (it) 1988-02-16
NO864108L (no) 1987-04-23
US4806534A (en) 1989-02-21
NO167570B (no) 1991-08-12
IL80229A0 (en) 1987-01-30
FI864260A (fi) 1987-04-23
IE862768L (en) 1987-04-22
FI864260A0 (fi) 1986-10-21
AU6427386A (en) 1987-04-30
JPS62161781A (ja) 1987-07-17
EG18109A (en) 1992-08-30
NZ217964A (en) 1990-04-26
AU596382B2 (en) 1990-05-03
EP0223744A3 (en) 1988-09-14
ES2002425A6 (es) 1988-08-01
CN86107544A (zh) 1987-11-25
EP0223744A2 (en) 1987-05-27
HU202863B (en) 1991-04-29
IT8522578A0 (it) 1985-10-22
IE58330B1 (en) 1993-09-08
PT83604B (pt) 1988-10-14
FI89167C (fi) 1993-08-25
ATE73453T1 (de) 1992-03-15
NO864108D0 (no) 1986-10-15
KR870004022A (ko) 1987-05-07
DK506386A (da) 1987-04-23
PH22766A (en) 1988-12-12
CA1330994C (en) 1994-07-26
KR910009269B1 (ko) 1991-11-08
PT83604A (en) 1986-11-01
ZA867941B (en) 1987-06-24
SG55192G (en) 1992-07-24
AR243883A1 (es) 1993-09-30
HUT45525A (en) 1988-07-28

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