GR852492B - - Google Patents

Info

Publication number
GR852492B
GR852492B GR852492A GR850102492A GR852492B GR 852492 B GR852492 B GR 852492B GR 852492 A GR852492 A GR 852492A GR 850102492 A GR850102492 A GR 850102492A GR 852492 B GR852492 B GR 852492B
Authority
GR
Greece
Prior art keywords
substantially pure
relates
phosphatidyl
synthetic
phosphatidyl choline
Prior art date
Application number
GR852492A
Other languages
English (en)
Inventor
Lajos Dr Tarcsay
Hansjorg Prof Dr Eibl
Peter Dr Frankhauser
Aniya Dr Peil
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of GR852492B publication Critical patent/GR852492B/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/829Liposomes, e.g. encapsulation
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GR852492A 1984-10-16 1985-10-15 GR852492B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH495184 1984-10-16

Publications (1)

Publication Number Publication Date
GR852492B true GR852492B (el) 1986-02-11

Family

ID=4285361

Family Applications (1)

Application Number Title Priority Date Filing Date
GR852492A GR852492B (el) 1984-10-16 1985-10-15

Country Status (21)

Country Link
US (1) US4971802A (el)
EP (1) EP0178624B1 (el)
JP (2) JPH0618773B2 (el)
KR (1) KR890000908B1 (el)
AT (1) ATE58474T1 (el)
AU (1) AU590221B2 (el)
CA (1) CA1260393A (el)
DD (1) DD239117A5 (el)
DE (1) DE3580648D1 (el)
DK (1) DK165220C (el)
ES (1) ES8700934A1 (el)
FI (1) FI86371C (el)
GR (1) GR852492B (el)
HK (1) HK135793A (el)
HU (1) HU198128B (el)
IE (1) IE58143B1 (el)
IL (1) IL76700A (el)
NO (1) NO171443C (el)
PH (1) PH22978A (el)
PT (1) PT81298B (el)
ZA (1) ZA857888B (el)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH668554A5 (de) * 1984-04-09 1989-01-13 Sandoz Ag Liposomen welche polypeptide mit interleukin-2-aktivitaet enthalten sowie verfahren zu ihrer herstellung.
US5243062A (en) * 1984-10-12 1993-09-07 Ciba-Geigy Corporation Substituted propane-phosphonous acid compounds
JPS61172833A (ja) * 1985-07-17 1986-08-04 Nakanishi Michio 消炎鎮痛性医薬組成物
US5133973A (en) * 1986-08-07 1992-07-28 Medice Chem.-Pharm. Fabrik Putter Gmbh & Co. Kg Pharmaceutical preparations
PT85537B (pt) * 1986-08-18 1990-06-29 Univ Texas Processo para a preparacao de um sistema de administracao farmaceutica contendo peptidos apresentando quimiotaxia
JPH0761940B2 (ja) * 1986-11-17 1995-07-05 株式会社資生堂 外皮用リポソ−ム製剤
EP0274219A3 (en) * 1986-12-04 1988-08-03 Takeda Chemical Industries, Ltd. Interleukin-2-containing liposome composition and method for the production thereof
US4944941A (en) * 1987-08-07 1990-07-31 Genentech, Inc. Methods and compositions for the treatment of lung conditions
US5830498A (en) * 1987-10-16 1998-11-03 Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
US5178875A (en) * 1991-01-14 1993-01-12 The Board Of Regents, The University Of Texas System Liposomal-polyene preliposomal powder and method for its preparation
FI874742A (fi) * 1987-10-28 1989-04-29 K & V Licencing Oy Foerfarande foer framstaellning av liposomer.
EP0331635A3 (en) * 1988-02-29 1990-02-28 The Board of Regents of the University of Texas System Preparations for treating bladder cancer
DE3806852A1 (de) * 1988-03-03 1989-09-14 Knoll Ag Neue (alpha)-aminodicarbonsaeure-derivate, ihre herstellung und verwendung
AU4525589A (en) * 1988-10-27 1990-05-14 Regents Of The University Of Minnesota Liposome immunoadjuvants containing il-2
US5466468A (en) * 1990-04-03 1995-11-14 Ciba-Geigy Corporation Parenterally administrable liposome formulation comprising synthetic lipids
IL97681A (en) * 1990-04-03 1996-01-31 Ciba Geigy Ag Liposome preparations containing synthetic lipids, given parenterally
US5270053A (en) * 1990-04-03 1993-12-14 Ciba-Geigy Corp. Parenterally administerable liposome formulation comprising synthetic lipid
US5162361A (en) * 1990-04-10 1992-11-10 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Method of treating diseases associated with elevated levels of interleukin 1
EP0467838A3 (en) * 1990-07-17 1992-09-02 Ciba-Geigy Ag Process for preparing an injectable liposome dispersion
AU664359B2 (en) * 1990-12-03 1995-11-16 Nexstar Pharmaceuticals, Inc. Prevention of synovial adhesions
AU3423493A (en) * 1991-12-31 1993-07-28 Zymogenetics Inc. Methods and compositions for reducing blood loss
PT100487B (pt) * 1992-05-14 1999-07-30 Univ Texas Formulacoes lipossomais de rifamicinas com elevada estabilidade e eficacia de incorporacao de antibiotico, e processo para a sua preparacao
DE59406065D1 (de) * 1993-03-24 1998-07-02 Ciba Geigy Ag Verfahren zur Herstellung einer Liposomendispersion im Hochdruckbereich
DE69407292T2 (de) * 1993-06-30 1998-06-25 Genentech Inc Verfahren zur herstellung von liposomen
US5474985A (en) * 1993-12-22 1995-12-12 The Regents Of The University Of California Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors
US6313106B1 (en) * 1995-06-07 2001-11-06 D-Pharm Ltd. Phospholipid derivatives of valproic acid and mixtures thereof
US5674888A (en) * 1995-06-07 1997-10-07 University Of California Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
US5599535A (en) * 1995-06-07 1997-02-04 Regents Of The University Of California Methods for the cyto-protection of the trabecular meshwork
ATE310505T1 (de) * 1996-05-14 2005-12-15 Stanislaw R Burzynski Liposomale antineoplaston therapie mit bemerkenswert verbesserter antineoplastischer aktivität
US6723338B1 (en) * 1999-04-01 2004-04-20 Inex Pharmaceuticals Corporation Compositions and methods for treating lymphoma
GB9921958D0 (en) * 1999-09-16 1999-11-17 Pharmacia & Upjohn Spa Formulations for parenteral use of estramustine phosphate and sulfoalkylether-cyclodextrins
JP4262480B2 (ja) * 2000-11-29 2009-05-13 ブラッコ インターナショナル ビー.ヴイ. 結合能を有するシアリル・ルイスx類似物
WO2007014754A1 (en) * 2005-08-02 2007-02-08 I.D.M. Immuno-Designed Molecules Process for the preparation of liposomal formulations
JP4931527B2 (ja) * 2006-09-20 2012-05-16 富士フイルム株式会社 フッ素化ホスファチジルセリン化合物
WO2008074487A2 (en) * 2006-12-19 2008-06-26 Novosom Ag Lipids and lipid assemblies comprising transfection enhancer elements
US9758536B2 (en) 2011-12-07 2017-09-12 Omega Protein Corporation Phospholipid compositions enriched for palmitoleic, myristoleic or lauroleic acid, their preparation and their use in treating metabolic and cardiovascular disease
MX2015005992A (es) 2012-11-20 2016-03-07 Spectrum Pharmaceuticals Inc Metodo mejorado para la preparacion de la vincristina liposomal encapsulada para el uso terapeutico.
TWI678213B (zh) 2015-07-22 2019-12-01 美商史倍壯製藥公司 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物
CN113995852B (zh) * 2021-11-08 2024-01-30 河北大学 Arg-脂质体微囊、微囊包封的鱼精蛋白-siRNA复合体及其制备方法和应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523965A (en) * 1976-03-19 1978-09-06 Ici Ltd Pharmaceutical compositions containing steroids
USRE30748E (en) * 1976-10-12 1981-09-22 Phosphatidyl quaternary ammonium compounds
DE2647395C2 (de) * 1976-10-20 1984-03-29 A. Nattermann & Cie GmbH, 5000 Köln Verfahren zur Herstellung von Estern des Glycerophosphocholins
GB2026340B (en) * 1978-07-03 1982-12-22 Ash P Stabilising microvesicles
FI75578C (fi) * 1979-07-25 1988-07-11 Ciba Geigy Ag Analogifoerfarande foer framstaellning av farmakologiskt verkande lipofila fosfatidylmuramylpeptider.
US4302459A (en) * 1980-03-19 1981-11-24 The United States Of America As Represented By The Secretary Of The Army Liposome carriers in leishmaniasis chemotherapy with 8-aminoquinoline derivatives
IL64397A0 (en) * 1981-01-07 1982-02-28 Weder Hans G Process for the preparation of liposomal medicaments
US4485045A (en) * 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
EP0088046B1 (de) * 1982-02-17 1987-12-09 Ciba-Geigy Ag Lipide in wässriger Phase
DE3209537A1 (de) * 1982-03-16 1983-09-22 Siemens AG, 1000 Berlin und 8000 München Elektrokleinmotor mit einer vorrichtung zum einstellen des axialspiels
DE3239817A1 (de) * 1982-07-06 1984-01-12 Max Planck Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Neue glycerinderivate zur synthese von phospholipiden
US4666893A (en) * 1983-02-15 1987-05-19 St. Thomas Institute Methods of inducing resistance to bacterial and viral infections
US4515736A (en) * 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
GB8322178D0 (en) * 1983-08-17 1983-09-21 Sterwin Ag Preparing aerosol compositions
DE3346525A1 (de) * 1983-12-22 1985-07-04 A. Nattermann & Cie GmbH, 5000 Köln Pharmazeutische zubereitung mit speziellen 1,2-diacyl-glycero-3-phosphocholinen zur behandlung von erkrankungen im magen-darmbereich
JPS6150912A (ja) * 1984-08-16 1986-03-13 Shionogi & Co Ltd リポソ−ム製剤の製造法
JPS62501631A (ja) * 1985-01-11 1987-07-02 ザ・リ−ジェンツ・オブ・ジ・ユニバ−シィティ・オブ・カリフォルニア リポソ−ムの保持法
US4774085A (en) * 1985-07-09 1988-09-27 501 Board of Regents, Univ. of Texas Pharmaceutical administration systems containing a mixture of immunomodulators

Also Published As

Publication number Publication date
EP0178624B1 (de) 1990-11-22
NO171443C (no) 1993-03-17
ES8700934A1 (es) 1986-11-16
HU198128B (en) 1989-08-28
DE3580648D1 (de) 1991-01-03
JPS6197215A (ja) 1986-05-15
JPH07238038A (ja) 1995-09-12
EP0178624A3 (en) 1987-05-27
EP0178624A2 (de) 1986-04-23
DK471085D0 (da) 1985-10-15
FI86371B (fi) 1992-05-15
JPH0816067B2 (ja) 1996-02-21
IE58143B1 (en) 1993-07-14
AU4871385A (en) 1986-04-24
PT81298A (en) 1985-11-01
PT81298B (pt) 1988-02-17
NO171443B (no) 1992-12-07
DD239117A5 (de) 1986-09-17
CA1260393A (en) 1989-09-26
DK165220B (da) 1992-10-26
AU590221B2 (en) 1989-11-02
JPH0618773B2 (ja) 1994-03-16
IL76700A0 (en) 1986-02-28
IL76700A (en) 1990-06-10
KR860003015A (ko) 1986-05-19
HUT40332A (en) 1986-12-28
KR890000908B1 (ko) 1989-04-13
DK165220C (da) 1993-03-22
HK135793A (en) 1993-12-17
FI853982A0 (fi) 1985-10-14
ES547889A0 (es) 1986-11-16
IE852527L (en) 1986-04-16
ZA857888B (en) 1986-05-28
FI86371C (fi) 1992-08-25
FI853982L (fi) 1986-04-17
ATE58474T1 (de) 1990-12-15
PH22978A (en) 1989-02-24
US4971802A (en) 1990-11-20
NO854085L (no) 1986-04-17
DK471085A (da) 1986-04-17

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