GR71704B - - Google Patents

Info

Publication number
GR71704B
GR71704B GR55500A GR780155500A GR71704B GR 71704 B GR71704 B GR 71704B GR 55500 A GR55500 A GR 55500A GR 780155500 A GR780155500 A GR 780155500A GR 71704 B GR71704 B GR 71704B
Authority
GR
Greece
Application number
GR55500A
Other languages
Greek (el)
Inventor
Federico Gennari
Original Assignee
Camozzi & C Biores Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Camozzi & C Biores Sas filed Critical Camozzi & C Biores Sas
Publication of GR71704B publication Critical patent/GR71704B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
GR55500A 1977-02-22 1978-02-20 GR71704B (enrdf_load_stackoverflow)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7290/77A GB1572137A (en) 1977-02-22 1977-02-22 Stable compositions for therapeutic use based on d,1-5-methyltetrahydrofolic acid and its salts

Publications (1)

Publication Number Publication Date
GR71704B true GR71704B (enrdf_load_stackoverflow) 1983-06-21

Family

ID=9830275

Family Applications (1)

Application Number Title Priority Date Filing Date
GR55500A GR71704B (enrdf_load_stackoverflow) 1977-02-22 1978-02-20

Country Status (32)

Country Link
JP (1) JPS5831353B2 (enrdf_load_stackoverflow)
AR (1) AR215162A1 (enrdf_load_stackoverflow)
AT (1) AT380020B (enrdf_load_stackoverflow)
AU (1) AU520715B2 (enrdf_load_stackoverflow)
BE (1) BE863808A (enrdf_load_stackoverflow)
CA (1) CA1093554A (enrdf_load_stackoverflow)
CH (1) CH635344A5 (enrdf_load_stackoverflow)
CZ (1) CZ279815B6 (enrdf_load_stackoverflow)
DD (1) DD134099A5 (enrdf_load_stackoverflow)
DE (1) DE2807393A1 (enrdf_load_stackoverflow)
DK (1) DK144944C (enrdf_load_stackoverflow)
EG (1) EG13399A (enrdf_load_stackoverflow)
ES (1) ES467153A1 (enrdf_load_stackoverflow)
FI (1) FI67082C (enrdf_load_stackoverflow)
FR (2) FR2381047A1 (enrdf_load_stackoverflow)
GB (1) GB1572137A (enrdf_load_stackoverflow)
GR (1) GR71704B (enrdf_load_stackoverflow)
HU (1) HU179422B (enrdf_load_stackoverflow)
IE (1) IE46402B1 (enrdf_load_stackoverflow)
IL (1) IL54052A (enrdf_load_stackoverflow)
IN (1) IN149574B (enrdf_load_stackoverflow)
LU (1) LU79067A1 (enrdf_load_stackoverflow)
MX (1) MX5288E (enrdf_load_stackoverflow)
NL (1) NL190285C (enrdf_load_stackoverflow)
NO (1) NO147793C (enrdf_load_stackoverflow)
NZ (1) NZ186465A (enrdf_load_stackoverflow)
PL (1) PL118654B1 (enrdf_load_stackoverflow)
PT (1) PT67656B (enrdf_load_stackoverflow)
SE (1) SE437028B (enrdf_load_stackoverflow)
SU (1) SU747427A3 (enrdf_load_stackoverflow)
YU (1) YU40505B (enrdf_load_stackoverflow)
ZA (1) ZA78837B (enrdf_load_stackoverflow)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5838285A (ja) * 1981-08-25 1983-03-05 Kanegafuchi Chem Ind Co Ltd ５−メチル−（６ｒｓ）−５，６，７，８−テトラヒドロ−ｌ−葉酸のマグネシウム塩またはその遊離酸の製法
GB8621268D0 (en) * 1986-09-03 1986-10-08 Univ Strathclyde Separation of substances
IT1229517B (it) * 1989-01-31 1991-09-03 Bioresearch Spa Impiego di acido 5-metiltetraidrofolico, di acido 5 formiltetraidrofolico, e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato adatte ad essere impiegate nella terapia dei disordini depressivi e composizioni farmaceutiche relative.
IT1229203B (it) * 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
NL8901432A (nl) * 1989-06-06 1991-01-02 Pharmachemie Bv Bij koelkasttemperatuur stabiele waterige folinaatoplossing, alsmede werkwijze ter bereiding daarvan.
CH680731A5 (enrdf_load_stackoverflow) * 1990-04-12 1992-10-30 Sapec Fine Chemicals
US5217974A (en) * 1991-03-29 1993-06-08 Eli Lilly And Company Method for treating gar-transformylase tumors in mammals and reducing mammalian toxicity
CH683261A5 (it) * 1991-10-10 1994-02-15 Applied Pharma Res Procedimento per la preparazione dell'acido metiltetraidrofolico nella forma (6(R,S)(-))N-5 e separazione del diastereoisomero attivo (6(S)(-))N-5) sotto forma di sali.
CH682665A5 (de) * 1991-10-29 1993-10-29 Sapec Fine Chemicals Verfahren zur Reinigung von rohen Erdalkalimetallsalzen von N(5)-Methyl-5,6,7,8-tetrahydrofolsäure.
US6162914A (en) * 1998-04-24 2000-12-19 Cerbios-Pharma S.A. Process for the reduction of pterins
CH693905A5 (de) * 1999-04-15 2004-04-15 Eprova Ag Stabile kristalline Salze von 5-Methyltetrahydrofolsäure.
CH698729B1 (de) * 2007-05-30 2009-10-15 Cerbios Pharma Sa Stabile, kristalline (6S)-N(5)-Methyl-5, 6,7,8-tetrahydrofolsäure.
CN103214487A (zh) * 2013-04-12 2013-07-24 张家港威胜生物医药有限公司 一种重要医药化工原料(6s)-5-甲基四氢叶酸盐的合成
WO2015193778A1 (en) 2014-06-16 2015-12-23 Mylan Laboratories Ltd. Crystalline form of levomefolate calcium
EP3844145A4 (en) 2018-08-28 2022-05-11 PMC Organometallix, Inc. Low free 2-mercaptoethanol ester and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL80276C (enrdf_load_stackoverflow) *
GB1293541A (en) * 1969-03-18 1972-10-18 John Alexander Blair Folic acid derivatives
US3856959A (en) * 1972-07-24 1974-12-24 Department Of Health Education Inhibition of leukemia utilizing 5-methyltetrahydrohomofolate
US4148999A (en) * 1977-08-22 1979-04-10 The Government Of The United States Of America Preparation and purification of citrovorum factor
CH649550A5 (en) * 1984-02-09 1985-05-31 Eprova Ag Process for the preparation of alkaline earth metal salts of 5-methyltetrahydrofolic acid

Also Published As

Publication number Publication date
AU520715B2 (en) 1982-02-25
ATA90378A (de) 1985-08-15
CA1093554A (en) 1981-01-13
SE437028B (sv) 1985-02-04
PL118654B1 (en) 1981-10-31
YU37978A (en) 1983-01-21
IE46402B1 (en) 1983-06-01
NL190285C (nl) 1994-01-03
FR2381047A1 (fr) 1978-09-15
JPS53124297A (en) 1978-10-30
FR2385397A1 (fr) 1978-10-27
DK76578A (da) 1978-08-23
SE7801973L (sv) 1978-08-23
IN149574B (enrdf_load_stackoverflow) 1982-01-30
BE863808A (fr) 1978-05-29
DK144944C (da) 1982-11-29
NL190285B (nl) 1993-08-02
MX5288E (es) 1983-06-06
EG13399A (en) 1981-12-31
FI780565A7 (fi) 1978-08-23
NO780594L (no) 1978-08-23
AT380020B (de) 1986-03-25
GB1572137A (en) 1980-07-23
PT67656B (en) 1979-07-19
PL204747A1 (pl) 1979-03-12
PT67656A (en) 1978-03-01
IL54052A0 (en) 1978-04-30
DK144944B (da) 1982-07-12
AU3343078A (en) 1979-08-30
CH635344A5 (en) 1983-03-31
FR2385397B1 (enrdf_load_stackoverflow) 1981-07-17
CZ279815B6 (cs) 1995-07-12
ES467153A1 (es) 1978-11-16
DE2807393C2 (enrdf_load_stackoverflow) 1990-06-13
HU179422B (en) 1982-10-28
FR2381047B1 (enrdf_load_stackoverflow) 1981-07-24
ZA78837B (en) 1979-09-26
NO147793B (no) 1983-03-07
CZ112978A3 (en) 1995-02-15
DE2807393A1 (de) 1978-09-07
NZ186465A (en) 1980-10-08
DD134099A5 (de) 1979-02-07
FI67082B (fi) 1984-09-28
IL54052A (en) 1981-07-31
IE780285L (en) 1978-08-22
JPS5831353B2 (ja) 1983-07-05
YU40505B (en) 1986-02-28
LU79067A1 (fr) 1978-06-27
FI67082C (fi) 1985-01-10
AR215162A1 (es) 1979-09-14
SU747427A3 (ru) 1980-07-23
NO147793C (no) 1983-06-15
NL7801775A (nl) 1978-08-24

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