GR3035139T3 - A process for producing immunosuppressives and a novel microbial species to be employed therein. - Google Patents

A process for producing immunosuppressives and a novel microbial species to be employed therein.

Info

Publication number
GR3035139T3
GR3035139T3 GR20000402825T GR20000402825T GR3035139T3 GR 3035139 T3 GR3035139 T3 GR 3035139T3 GR 20000402825 T GR20000402825 T GR 20000402825T GR 20000402825 T GR20000402825 T GR 20000402825T GR 3035139 T3 GR3035139 T3 GR 3035139T3
Authority
GR
Greece
Prior art keywords
producing
immunosuppressives
employed
microbial species
novel microbial
Prior art date
Application number
GR20000402825T
Other languages
English (en)
Inventor
Juhani Lundell
Anja Kopio
Timo Korpela
Matti Ankelo
Original Assignee
Leiras Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leiras Oy filed Critical Leiras Oy
Publication of GR3035139T3 publication Critical patent/GR3035139T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
GR20000402825T 1992-12-30 2000-12-22 A process for producing immunosuppressives and a novel microbial species to be employed therein. GR3035139T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI925940A FI92334C (fi) 1992-12-30 1992-12-30 Menetelmä syklosporiinien tuottamiseksi ja menetelmässä käytettävä uusi Tolypocladium-kanta
PCT/FI1993/000568 WO1994016091A1 (en) 1992-12-30 1993-12-29 A process for producing immunosuppressives and a novel microbial species to be employed therein

Publications (1)

Publication Number Publication Date
GR3035139T3 true GR3035139T3 (en) 2001-04-30

Family

ID=8536483

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000402825T GR3035139T3 (en) 1992-12-30 2000-12-22 A process for producing immunosuppressives and a novel microbial species to be employed therein.

Country Status (20)

Country Link
US (1) US5409816A (el)
EP (1) EP0677116B1 (el)
JP (1) JP3530531B2 (el)
KR (1) KR100283503B1 (el)
AT (1) ATE196655T1 (el)
AU (1) AU674723B2 (el)
CA (1) CA2152963C (el)
DE (1) DE69329500T2 (el)
DK (1) DK0677116T3 (el)
EE (1) EE03114B1 (el)
ES (1) ES2150980T3 (el)
FI (1) FI92334C (el)
GR (1) GR3035139T3 (el)
HK (1) HK1014035A1 (el)
HU (1) HU217683B (el)
PL (1) PL177023B1 (el)
PT (1) PT677116E (el)
RU (1) RU2112807C1 (el)
SG (1) SG49072A1 (el)
WO (1) WO1994016091A1 (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0725076B1 (en) * 1995-02-01 2001-06-06 National Research Development Corporation of India A process for the preparation of cyclosporin A from tolypocladium species
KR100360675B1 (ko) * 1995-02-28 2003-01-14 내셔널 리서어치 디벨럽먼트 코포레이션 사이클로스포린a제조방법
US5709797A (en) * 1996-06-05 1998-01-20 Poli Industria Chimica S.P.A. Method of isolating cyclosporins
US5747330A (en) * 1996-06-05 1998-05-05 Poli Industria Chimica Antibiotic producing microbe
US6423233B1 (en) * 2000-08-15 2002-07-23 Biogal Gyogyszergyar Rt. Purification process
KR100496929B1 (ko) * 1997-03-25 2005-09-30 테바 기오기스제르갸르 레스즈베니타르사사그 시클로스포린의정제방법
HU223054B1 (hu) * 1997-03-25 2004-03-01 BIOGAL Gyógyszergyár Rt. Tisztítási eljárás nagytisztaságú ciklosporin A előállítására
DK0991660T3 (da) 1997-10-08 2006-02-13 Isotechnika Inc Deuterede og udeuterede cyclosporinanaloger og deres anvendelse som immunmodulerende midler
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
DE69939335D1 (de) 1998-12-30 2008-09-25 Dexcel Ltd Dispergierbares konzentrat zur verabreichung von cyclosporin
US7732404B2 (en) * 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
CA2396381A1 (en) * 2000-01-20 2001-07-26 Akira Yanagawa Nasally administrable cyclic peptide compositions
CA2401700A1 (en) * 2000-02-29 2001-09-07 Biocon India Limited Manufacture and purification of cyclosporin a
PL210841B1 (pl) 2001-10-19 2012-03-30 Isotechnika Inc Sposób wytwarzania mieszaniny izomerów (E) i (Z) ISATX247
US7862552B2 (en) * 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
EP2151450A1 (de) * 2008-07-29 2010-02-10 Sandoz AG Verfahren zur Aufarbeitung von mikrobiologisch hergestellten zyklischen Oligopeptiden
WO2019067423A1 (en) * 2017-09-29 2019-04-04 Valent Biosciences Llc NEW TOLYPOCLADIUM ALBUM STRAIN
RU2679051C1 (ru) * 2018-02-16 2019-02-05 Федеральное государственное учреждение Федеральный исследовательский центр "Фундаментальные основы биотехнологии" Российской академии наук Штамм streptomyces hygroscopicus bkm ac-2737d - продуцент антибиотика рапамицина и способ увеличения его продуктивности

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE295870C (el) *
US3878047A (en) * 1973-02-02 1975-04-15 Upjohn Co Process for production of AT-125
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
US4215199A (en) * 1978-06-05 1980-07-29 Sandoz Ltd. Antibiotic production
DD298276A5 (de) * 1988-10-11 1992-02-13 Institut Fuer Mikrobiologie Und Experimentelle Therapie,De Verfahren zur herstellung von cyclosporin a
DD295870A5 (de) * 1988-10-11 1991-11-14 Arzneimittelwerk Dresden Gmbh,De Verfahren zur mikrobiellen gewinnung von cyclosporinen
HU201577B (en) * 1988-12-20 1990-11-28 Gyogyszerkutato Intezet Process for producing cyclosporin antibiotics
WO1992013094A1 (fr) * 1991-01-25 1992-08-06 Fujisawa Pharmaceutical Co., Ltd. Procede pour produire de la cyclosporine a et/ou c
DE59106428D1 (de) * 1991-04-06 1995-10-12 Dresden Arzneimittel Verfahren zur fermentativen Herstellung und Isolierung von Cyclosporin A sowie neue Cyclosporin- bildende Stämme.

Also Published As

Publication number Publication date
HK1014035A1 (en) 1999-09-17
AU674723B2 (en) 1997-01-09
KR100283503B1 (ko) 2001-03-02
ES2150980T3 (es) 2000-12-16
AU5701494A (en) 1994-08-15
FI92334B (fi) 1994-07-15
KR960700346A (ko) 1996-01-19
EE03114B1 (et) 1998-08-17
JP3530531B2 (ja) 2004-05-24
EP0677116A1 (en) 1995-10-18
HU9501951D0 (en) 1995-08-28
FI92334C (fi) 1994-10-25
PL177023B1 (pl) 1999-09-30
HUT72702A (en) 1996-05-28
PL309613A1 (en) 1995-10-30
EP0677116B1 (en) 2000-09-27
DE69329500T2 (de) 2001-06-07
FI925940A0 (fi) 1992-12-30
ATE196655T1 (de) 2000-10-15
DK0677116T3 (da) 2000-12-27
CA2152963C (en) 2003-05-27
CA2152963A1 (en) 1994-07-21
RU2112807C1 (ru) 1998-06-10
SG49072A1 (en) 1998-05-18
DE69329500D1 (de) 2000-11-02
WO1994016091A1 (en) 1994-07-21
PT677116E (pt) 2001-01-31
HU217683B (hu) 2000-03-28
US5409816A (en) 1995-04-25
JPH08505059A (ja) 1996-06-04

Similar Documents

Publication Publication Date Title
GR3035139T3 (en) A process for producing immunosuppressives and a novel microbial species to be employed therein.
UA19162A (uk) Спосіб одержаhhя аhтибіотика s541, штами стрептоміцетів - продуцеhти аhтибіотика s541
UA32566C2 (uk) Спосіб одержання штаму мікроорганізму, спосіб продукування триптофану
UA13320A (uk) Спосіб одержаhhя комплексhого аhтибіотика циклоспоріhу та/або його компоhеhтів та штам грибка tolypocladium varium
HU9801420D0 (en) Process for producing l-amino acids by fermentition
GB1474129A (en) Method for the production of d-ribose
DE59105850D1 (de) Mikrobiologisches Verfahren zur Herstellung von hydroxylierten Heterocyclen.
IL83225A (en) Antibiotic a 42867,process for its production and pharmaceutical compositions containing it
JPS55102393A (en) Enzymatic preparation of tyramine
AU3157893A (en) Process for preparing neuraminidase
CA2099857A1 (en) Microbiological process for the production of 5-hydroxypyrazinecarboxylic acid
JPS5750892A (en) Microbial preparation of valeric acid derivative
CA2063225A1 (en) Microbiological process for the production of 6-hydroxypicolinic acid
CA2062667A1 (en) Microbiological process for the production of 6-hydroxynicotinic acid
MY102317A (en) Novel microorganisms and a method for production of glutamic acid using the same.
JPS54129182A (en) Production of bacterial cells
TH12886A (th) กรรมวิธีสำหรับการผลิตแอล-ไลซีนโดยการหมัก
UA24059A (uk) Спосіб утилізації метаhовмісhих шахтhих газів

Legal Events

Date Code Title Description
ML Lapse due to non-payment of fees