GR3034631T3 - Treatment of diabetes - Google Patents
Treatment of diabetesInfo
- Publication number
- GR3034631T3 GR3034631T3 GR20000402317T GR20000402317T GR3034631T3 GR 3034631 T3 GR3034631 T3 GR 3034631T3 GR 20000402317 T GR20000402317 T GR 20000402317T GR 20000402317 T GR20000402317 T GR 20000402317T GR 3034631 T3 GR3034631 T3 GR 3034631T3
- Authority
- GR
- Greece
- Prior art keywords
- peptide
- diabetes
- treatment
- glucagon
- insulin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9409496A GB9409496D0 (en) | 1994-05-12 | 1994-05-12 | Method for improving glycaemic control in diabetes |
PCT/CA1995/000287 WO1995031214A1 (en) | 1994-05-12 | 1995-05-12 | Treatment of diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
GR3034631T3 true GR3034631T3 (en) | 2001-01-31 |
Family
ID=10755008
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GR20000402317T GR3034631T3 (en) | 1994-05-12 | 2000-10-16 | Treatment of diabetes |
Country Status (13)
Country | Link |
---|---|
US (3) | US6899883B2 (el) |
EP (1) | EP0762890B1 (el) |
JP (2) | JPH10500114A (el) |
AT (1) | ATE194918T1 (el) |
AU (1) | AU711611B2 (el) |
CA (1) | CA2190112A1 (el) |
DE (1) | DE69518154T2 (el) |
DK (1) | DK0762890T3 (el) |
ES (1) | ES2150566T3 (el) |
GB (1) | GB9409496D0 (el) |
GR (1) | GR3034631T3 (el) |
PT (1) | PT762890E (el) |
WO (1) | WO1995031214A1 (el) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6849708B1 (en) | 1986-05-05 | 2005-02-01 | The General Hospital Corporation | Insulinotropic hormone and uses thereof |
US5614492A (en) * | 1986-05-05 | 1997-03-25 | The General Hospital Corporation | Insulinotropic hormone GLP-1 (7-36) and uses thereof |
US7138486B2 (en) | 1986-05-05 | 2006-11-21 | The General Hospital Corporation | Insulinotropic hormone derivatives and uses thereof |
US6558952B1 (en) * | 1992-12-14 | 2003-05-06 | Waratah Pharmaceuticals, Inc. | Treatment for diabetes |
US6284727B1 (en) | 1993-04-07 | 2001-09-04 | Scios, Inc. | Prolonged delivery of peptides |
GB9409496D0 (en) | 1994-05-12 | 1994-06-29 | London Health Ass | Method for improving glycaemic control in diabetes |
MA24129A1 (fr) * | 1996-08-30 | 1997-10-01 | Novozymes As | Procede pour deformer une matiere textile cellulosique |
US6458924B2 (en) | 1996-08-30 | 2002-10-01 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
US6268343B1 (en) | 1996-08-30 | 2001-07-31 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
US7235627B2 (en) | 1996-08-30 | 2007-06-26 | Novo Nordisk A/S | Derivatives of GLP-1 analogs |
EP1826216A1 (en) * | 1996-08-30 | 2007-08-29 | Novo Nordisk A/S | Glp-1 derivatives |
UA65549C2 (uk) | 1996-11-05 | 2004-04-15 | Елі Ліллі Енд Компані | Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція |
ATE273996T1 (de) * | 1997-09-12 | 2004-09-15 | Pharis Biotec Gmbh | Zusammensetzung zur therapie von diabetes mellitus und fettsucht |
JP2002506792A (ja) * | 1998-02-27 | 2002-03-05 | ノボ ノルディスク アクティーゼルスカブ | N末端修飾glp−1誘導体 |
EP1056774A1 (en) * | 1998-02-27 | 2000-12-06 | Novo Nordisk A/S | N-terminally truncated glp-1 derivatives |
DE69942306D1 (de) * | 1998-02-27 | 2010-06-10 | Novo Nordisk As | Abkömmlinge von glp-1 analogen |
US20040037818A1 (en) * | 1998-07-30 | 2004-02-26 | Brand Stephen J. | Treatment for diabetes |
ES2335066T3 (es) | 1998-08-10 | 2010-03-18 | The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services | Diferenciacion de celulas no productoras de insulina en celulas productoras de insulina glp-1 o exendina-4 y utilizaciones de las mismas. |
AU5195699A (en) * | 1998-08-11 | 2000-03-06 | Sumitomo Pharmaceuticals Company, Limited | Blood sugar level controlling agent |
WO2000037098A1 (en) * | 1998-12-22 | 2000-06-29 | Eli Lilly And Company | Shelf-stable formulation of glucagon-like peptide-1 |
SI1140148T1 (sl) * | 1998-12-22 | 2006-04-30 | Lilly Co Eli | Stabilna formulacija raztopine glukagonu podobnega peptida-1 |
AU5325200A (en) | 1999-06-21 | 2001-01-09 | Eli Lilly And Company | Synergistic use of thiazolidinediones with glucagon-like peptide-1 and agonists thereof to treat metabolic instability associated with non-insulin dependent diabetes |
MXPA02006118A (es) | 2000-10-20 | 2004-08-23 | Amylin Pharmaceuticals Inc | Tratamiento de la invernacion del miocardio y cardiopatia diabetica con un peptido glp-1. |
ATE411077T1 (de) | 2001-01-12 | 2008-10-15 | Waratah Pharmaceuticals Inc | Zusammensetzungen, welche gastrin/cck- rezeptorligande und egf-rezeptorligande enthalten,zur induzierung der neogenese von inselzellen |
US7576050B2 (en) | 2001-07-31 | 2009-08-18 | The United States Of America As Represented By The Department Of Health And Human Services | GLP-1 exendin-4 peptide analogs and uses thereof |
CN1635900A (zh) * | 2001-08-28 | 2005-07-06 | 伊莱利利公司 | Glp-1和基础胰岛素的预混合物 |
CA2463803A1 (en) | 2001-10-19 | 2003-05-01 | Eli Lilly And Company | Biphasic mixtures of glp-1 and insulin |
US7037504B2 (en) * | 2001-10-23 | 2006-05-02 | Waratah Pharmaceuticals, Inc. | Epidermal growth factor protein and gene, and methods of use therefor |
ES2500918T3 (es) | 2001-12-21 | 2014-10-01 | Human Genome Sciences, Inc. | Proteínas de fusión de albúmina e interferón beta |
US7635463B2 (en) * | 2002-02-27 | 2009-12-22 | Pharmain Corporation | Compositions for delivery of therapeutics and other materials |
CA2476589C (en) * | 2002-02-27 | 2014-02-25 | Pharmain, Ltd. | Compositions for delivery of therapeutics and other materials, and methods of making and using the same |
JP2005527224A (ja) * | 2002-05-24 | 2005-09-15 | ワラタ ファーマシューティカルズ, インコーポレイテッド | 糖尿病の処置 |
EP1837031B1 (en) | 2002-06-07 | 2009-10-14 | Waratah Pharmaceuticals, Inc. | Compositions and methods for treating diabetes |
CA2486584A1 (en) * | 2002-06-07 | 2003-12-18 | Waratah Pharmaceuticals, Inc. | Compositions and methods for treating diabetes |
WO2003105897A1 (en) | 2002-06-14 | 2003-12-24 | Novo Nordisk A/S | Combined use of a modulator of cd3 and a glp-1 compound |
ES2320754T3 (es) * | 2002-10-22 | 2009-05-28 | Waratah Pharmaceuticals, Inc. | Tratamiento de la diabetes. |
US20040229810A1 (en) * | 2002-10-22 | 2004-11-18 | Antonio Cruz | Gastrin compositions and formulations, and methods of use and preparation |
US7655618B2 (en) * | 2002-12-27 | 2010-02-02 | Diobex, Inc. | Compositions and methods for the prevention and control of insulin-induced hypoglycemia |
US7314859B2 (en) * | 2002-12-27 | 2008-01-01 | Diobex, Inc. | Compositions and methods for the prevention and control of insulin-induced hypoglycemia |
US20080039379A1 (en) * | 2003-05-27 | 2008-02-14 | Waratah Pharmaceuticals, Inc. | Compositions Comprising Gastrin Compounds and Their Use in Diabetes |
WO2005023291A2 (en) * | 2003-09-11 | 2005-03-17 | Novo Nordisk A/S | Use of glp1-agonists in the treatment of patients with type i diabetes |
US20090202494A1 (en) * | 2004-01-30 | 2009-08-13 | Antonio Cruz | Combined use of glp-1 agonists and gastrin for regulating blood glucose levels |
WO2005112977A2 (en) * | 2004-04-23 | 2005-12-01 | Pharmain, Ltd. | Compositions for treatment with glucagon-like peptide, and methods of making and using the same |
EP1765873A4 (en) * | 2004-07-01 | 2009-07-01 | Waratah Pharmaceuticals Inc | COMBINED USE OF CD3 AGONIST AND GASTRIN FOR THE TREATMENT OF DIABETES |
US20090215069A1 (en) * | 2004-07-28 | 2009-08-27 | Andreas Christ | Pancreatic polypeptide as target/marker of beta cell failure |
WO2006029634A2 (en) * | 2004-09-17 | 2006-03-23 | Novo Nordisk A/S | Pharmaceutical compositions containing insulin and insulinotropic peptide |
JP5248113B2 (ja) * | 2004-11-12 | 2013-07-31 | ノヴォ ノルディスク アー/エス | ペプチドの安定な処方 |
AU2005310367A1 (en) * | 2004-12-03 | 2006-06-08 | Mederio Ag | A medical product comprising a glucagon-like peptide medicament intended for pulmonary inhalation |
SE0402976L (sv) * | 2004-12-03 | 2006-06-04 | Mederio Ag | Medicinsk produkt |
RU2007149288A (ru) * | 2005-05-27 | 2009-07-10 | Асубио Фарма Ко., Лтд. (Jp) | Средство для снижения устойчивости к инсулину |
EP1920061A4 (en) * | 2005-07-27 | 2009-05-13 | Wang Qinghua | GLP / 1 / EXENDIN 4 IGG FC FUSION CONSTRUCTS FOR THE TREATMENT OF DIABETES |
CA2625150A1 (en) * | 2005-10-07 | 2007-04-19 | Waratah Pharmaceuticals, Inc. | Combined use of dpp-iv inhibitors and gastrin compounds |
KR20150125732A (ko) | 2005-12-19 | 2015-11-09 | 파마인 코포레이션 | 치료제를 전달하기 위한 소수성 코어 담체 조성물, 이 조성물의 제조 방법 및 그 조성물의 이용 방법 |
US7960336B2 (en) | 2007-08-03 | 2011-06-14 | Pharmain Corporation | Composition for long-acting peptide analogs |
US8563527B2 (en) * | 2007-08-20 | 2013-10-22 | Pharmain Corporation | Oligonucleotide core carrier compositions for delivery of nucleic acid-containing therapeutic agents, methods of making and using the same |
CA2705821A1 (en) | 2007-11-16 | 2009-05-22 | Novo Nordisk A/S | Pharmaceutical compositions containing insulin and an insulinotropic peptide |
US20090176892A1 (en) | 2008-01-09 | 2009-07-09 | Pharmain Corporation | Soluble Hydrophobic Core Carrier Compositions for Delivery of Therapeutic Agents, Methods of Making and Using the Same |
BR112012012945A2 (pt) | 2009-11-25 | 2020-12-29 | Arisgen Sa | Composição de liberação mucosal, seu método de produção, complexo de peptídeo pré-formado, kit e uso de um agente ativo de peptídeo |
WO2013128003A1 (en) * | 2012-03-01 | 2013-09-06 | Novo Nordisk A/S | N-terminally modified oligopeptides and uses thereof |
CN104371019B (zh) | 2013-08-13 | 2019-09-10 | 鸿运华宁(杭州)生物医药有限公司 | 一种能与glp-1r特异性结合的抗体及其与glp-1的融合蛋白质 |
JP6731953B2 (ja) | 2015-02-11 | 2020-07-29 | ジーエムエーエックス バイオファーム エルエルシー. | Glp−1r抗体融合タンパク質の安定な医薬溶液製剤 |
WO2018055539A1 (en) | 2016-09-22 | 2018-03-29 | Wockhardt Limited | Pharmaceutical composition containing buffered insulin glargine and glp-1 analogue |
KR102665710B1 (ko) | 2017-08-24 | 2024-05-14 | 노보 노르디스크 에이/에스 | Glp-1 조성물 및 그 용도 |
WO2021142733A1 (en) * | 2020-01-16 | 2021-07-22 | Shanghai Benemae Pharmaceutical Corporation | Combinational therapy comprising glp-1 and/or glp-1 analogs, and insulin and/or insulin analogs |
WO2021142736A1 (en) * | 2020-01-16 | 2021-07-22 | Shanghai Benemae Pharmaceutical Corporation | Dosing regimen of glp-1 |
IL294521A (en) | 2020-02-18 | 2022-09-01 | Novo Nordisk As | glp-1 compounds and their uses |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK283180A (da) | 1980-07-01 | 1982-01-02 | Novo Industri As | Polypeptider og derivater deraf |
NZ202757A (en) | 1981-12-23 | 1985-11-08 | Novo Industri As | Peptides and medicaments |
US5120712A (en) | 1986-05-05 | 1992-06-09 | The General Hospital Corporation | Insulinotropic hormone |
US5118666A (en) | 1986-05-05 | 1992-06-02 | The General Hospital Corporation | Insulinotropic hormone |
DE68929217T2 (de) | 1989-03-20 | 2000-11-30 | The General Hospital Corp., Boston | Insulinotropes hormon |
ES2113879T3 (es) | 1990-01-24 | 1998-05-16 | Douglas I Buckley | Analogos de glp-1 utiles para el tratamiento de diabetes. |
US5187154A (en) * | 1990-12-13 | 1993-02-16 | Board Of Regents, The University Of Texas System | Diagnosis and treatment of humans with diabetes or at risk to develop diabetes |
US5234906A (en) | 1991-01-10 | 1993-08-10 | Amylin Pharmaceuticals, Inc. | Hyperglycemic compositions |
DK36392D0 (da) | 1992-03-19 | 1992-03-19 | Novo Nordisk As | Anvendelse af kemisk forbindelse |
JP2575298B2 (ja) | 1992-06-15 | 1997-01-22 | フアイザー・インコーポレイテツド | グルカゴン様ペプチド及びインシュリノトロピン誘導体 |
US5885956A (en) * | 1992-12-14 | 1999-03-23 | Research Triangle Pharmaceuticals | Treatment for diabetes using a gastrin/CCK receptor ligand and an EGF receptor ligand |
US6558952B1 (en) * | 1992-12-14 | 2003-05-06 | Waratah Pharmaceuticals, Inc. | Treatment for diabetes |
HU225496B1 (en) | 1993-04-07 | 2007-01-29 | Scios Inc | Pharmaceutical compositions of prolonged delivery, containing peptides |
US5424286A (en) * | 1993-05-24 | 1995-06-13 | Eng; John | Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same |
GB9409496D0 (en) | 1994-05-12 | 1994-06-29 | London Health Ass | Method for improving glycaemic control in diabetes |
US5512549A (en) | 1994-10-18 | 1996-04-30 | Eli Lilly And Company | Glucagon-like insulinotropic peptide analogs, compositions, and methods of use |
CA2283834A1 (en) | 1997-03-31 | 1998-10-08 | James Arthur Hoffmann | Glucagon-like peptide-1 analogs |
US20040037818A1 (en) * | 1998-07-30 | 2004-02-26 | Brand Stephen J. | Treatment for diabetes |
ATE411077T1 (de) * | 2001-01-12 | 2008-10-15 | Waratah Pharmaceuticals Inc | Zusammensetzungen, welche gastrin/cck- rezeptorligande und egf-rezeptorligande enthalten,zur induzierung der neogenese von inselzellen |
US7202080B2 (en) * | 2001-03-29 | 2007-04-10 | Ixion Biotechnology, Inc. | Method for transdifferentiation of non-pancreatic stem cells to the pancreatic differentiation pathway |
US7037504B2 (en) * | 2001-10-23 | 2006-05-02 | Waratah Pharmaceuticals, Inc. | Epidermal growth factor protein and gene, and methods of use therefor |
JP2005527224A (ja) * | 2002-05-24 | 2005-09-15 | ワラタ ファーマシューティカルズ, インコーポレイテッド | 糖尿病の処置 |
EP1837031B1 (en) * | 2002-06-07 | 2009-10-14 | Waratah Pharmaceuticals, Inc. | Compositions and methods for treating diabetes |
CA2486584A1 (en) * | 2002-06-07 | 2003-12-18 | Waratah Pharmaceuticals, Inc. | Compositions and methods for treating diabetes |
US20040229810A1 (en) * | 2002-10-22 | 2004-11-18 | Antonio Cruz | Gastrin compositions and formulations, and methods of use and preparation |
ES2320754T3 (es) * | 2002-10-22 | 2009-05-28 | Waratah Pharmaceuticals, Inc. | Tratamiento de la diabetes. |
-
1994
- 1994-05-12 GB GB9409496A patent/GB9409496D0/en active Pending
-
1995
- 1995-05-12 AT AT95917874T patent/ATE194918T1/de not_active IP Right Cessation
- 1995-05-12 DK DK95917874T patent/DK0762890T3/da active
- 1995-05-12 JP JP7529262A patent/JPH10500114A/ja not_active Withdrawn
- 1995-05-12 DE DE69518154T patent/DE69518154T2/de not_active Expired - Fee Related
- 1995-05-12 EP EP95917874A patent/EP0762890B1/en not_active Revoked
- 1995-05-12 AU AU24044/95A patent/AU711611B2/en not_active Withdrawn - After Issue
- 1995-05-12 PT PT95917874T patent/PT762890E/pt unknown
- 1995-05-12 CA CA002190112A patent/CA2190112A1/en not_active Withdrawn
- 1995-05-12 WO PCT/CA1995/000287 patent/WO1995031214A1/en not_active Application Discontinuation
- 1995-05-12 US US08/737,446 patent/US6899883B2/en not_active Expired - Fee Related
- 1995-05-12 ES ES95917874T patent/ES2150566T3/es not_active Expired - Lifetime
-
1999
- 1999-03-29 US US09/280,020 patent/US6989148B2/en not_active Expired - Fee Related
-
2000
- 2000-10-16 GR GR20000402317T patent/GR3034631T3/el not_active IP Right Cessation
-
2007
- 2007-02-08 JP JP2007029369A patent/JP2007131640A/ja active Pending
- 2007-12-04 US US11/987,771 patent/US20080286301A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
GB9409496D0 (en) | 1994-06-29 |
ES2150566T3 (es) | 2000-12-01 |
US20020119146A1 (en) | 2002-08-29 |
AU2404495A (en) | 1995-12-05 |
US6989148B2 (en) | 2006-01-24 |
JP2007131640A (ja) | 2007-05-31 |
DE69518154T2 (de) | 2000-12-14 |
EP0762890B1 (en) | 2000-07-26 |
EP0762890A1 (en) | 1997-03-19 |
US20080286301A1 (en) | 2008-11-20 |
JPH10500114A (ja) | 1998-01-06 |
WO1995031214A1 (en) | 1995-11-23 |
CA2190112A1 (en) | 1995-05-12 |
DK0762890T3 (da) | 2000-11-13 |
PT762890E (pt) | 2000-11-30 |
DE69518154D1 (de) | 2000-08-31 |
ATE194918T1 (de) | 2000-08-15 |
AU711611B2 (en) | 1999-10-14 |
US6899883B2 (en) | 2005-05-31 |
US20020160008A1 (en) | 2002-10-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ML | Lapse due to non-payment of fees |