ATE411077T1 - Zusammensetzungen, welche gastrin/cck- rezeptorligande und egf-rezeptorligande enthalten,zur induzierung der neogenese von inselzellen - Google Patents
Zusammensetzungen, welche gastrin/cck- rezeptorligande und egf-rezeptorligande enthalten,zur induzierung der neogenese von inselzellenInfo
- Publication number
- ATE411077T1 ATE411077T1 AT02708990T AT02708990T ATE411077T1 AT E411077 T1 ATE411077 T1 AT E411077T1 AT 02708990 T AT02708990 T AT 02708990T AT 02708990 T AT02708990 T AT 02708990T AT E411077 T1 ATE411077 T1 AT E411077T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor ligand
- inducing
- compositions containing
- treatment
- gastrin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH] (Somatotropin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2207—Gastrins; Cholecystokinins [CCK]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26163801P | 2001-01-12 | 2001-01-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE411077T1 true ATE411077T1 (de) | 2008-10-15 |
Family
ID=22994183
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02708990T ATE411077T1 (de) | 2001-01-12 | 2002-01-11 | Zusammensetzungen, welche gastrin/cck- rezeptorligande und egf-rezeptorligande enthalten,zur induzierung der neogenese von inselzellen |
Country Status (13)
Country | Link |
---|---|
US (2) | US6992060B2 (de) |
EP (1) | EP1351742B1 (de) |
JP (1) | JP2004520345A (de) |
KR (1) | KR20040064605A (de) |
CN (1) | CN1486204A (de) |
AT (1) | ATE411077T1 (de) |
AU (1) | AU2002243501B2 (de) |
CA (1) | CA2434330A1 (de) |
DE (1) | DE60229352D1 (de) |
ES (1) | ES2315350T3 (de) |
IL (1) | IL156828A0 (de) |
WO (1) | WO2002055152A2 (de) |
ZA (1) | ZA200305347B (de) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6558952B1 (en) * | 1992-12-14 | 2003-05-06 | Waratah Pharmaceuticals, Inc. | Treatment for diabetes |
GB9409496D0 (en) * | 1994-05-12 | 1994-06-29 | London Health Ass | Method for improving glycaemic control in diabetes |
US20040037818A1 (en) * | 1998-07-30 | 2004-02-26 | Brand Stephen J. | Treatment for diabetes |
US20060014684A1 (en) * | 2000-03-03 | 2006-01-19 | University Technologies International Inc. | Novel uses of EGF |
WO2002055152A2 (en) * | 2001-01-12 | 2002-07-18 | Waratah Pharmaceuticals, Inc. | Composition for inducing islet neogenesis, containing gastrin/cck receptor ligands and egf receptor ligands |
WO2003018782A2 (en) | 2001-08-30 | 2003-03-06 | Stem Cell Therapeutics Inc. | Differentiation of neural stem cells and therapeutic use theeof |
CA2460184A1 (en) | 2001-09-14 | 2003-03-27 | Stem Cell Therapeutics Inc. | Prolactin induced increase in neural stem cell numbers and therapeutical use thereof |
US20030054551A1 (en) * | 2001-09-18 | 2003-03-20 | Stem Cell Therapeutics Inc. | Effect of growth hormone and IGF-1 on neural stem cells |
US7037504B2 (en) * | 2001-10-23 | 2006-05-02 | Waratah Pharmaceuticals, Inc. | Epidermal growth factor protein and gene, and methods of use therefor |
EP1441754A1 (de) * | 2001-10-26 | 2004-08-04 | University Technologies International Inc. | Verwendung von egf zur behandlung von pathogeninfektionen des urogenitalstraktes |
US20060234373A1 (en) * | 2002-05-24 | 2006-10-19 | Alex Rabinovitch | Treatment for diabetes |
CN100448483C (zh) * | 2002-05-24 | 2009-01-07 | 瓦拉塔药品公司 | 糖尿病的治疗 |
KR20050048542A (ko) * | 2002-06-07 | 2005-05-24 | 와라타 파마수티컬즈, 인크. | 당뇨병의 치료를 위한 조성물 및 방법 |
EP1837031B1 (de) * | 2002-06-07 | 2009-10-14 | Waratah Pharmaceuticals, Inc. | Methoden und Kompositionen um Diabetes zu behandeln |
EP1546198A1 (de) * | 2002-07-31 | 2005-06-29 | Stem Cell Therapeutics Inc. | Verfahren zur verbesserung der proliferation, der differenzierung und des berlebens von neuralen stammzellen unter verwendung von pituitary adenylate cyclase activating polypeptide (pacap) |
KR20050074492A (ko) * | 2002-10-22 | 2005-07-18 | 와라타 파마수티컬즈, 인크. | 당뇨병의 치료 |
US20040229810A1 (en) * | 2002-10-22 | 2004-11-18 | Antonio Cruz | Gastrin compositions and formulations, and methods of use and preparation |
US20060009516A1 (en) * | 2002-10-24 | 2006-01-12 | Mcgill University | Use of ingap for reversing diabetes |
MXPA05012605A (es) * | 2003-05-27 | 2006-02-22 | Waratah Pharmaceuticals Inc | Composiciones que comprenden compuestos de gastrina y sus usos en la diabetes. |
US20080039379A1 (en) * | 2003-05-27 | 2008-02-14 | Waratah Pharmaceuticals, Inc. | Compositions Comprising Gastrin Compounds and Their Use in Diabetes |
US20070111932A1 (en) * | 2003-07-31 | 2007-05-17 | Stem Cell Therapeutics Inc. | Method of enhancing and/or inducing neuronal migration using erythropoietin |
US20090202494A1 (en) * | 2004-01-30 | 2009-08-13 | Antonio Cruz | Combined use of glp-1 agonists and gastrin for regulating blood glucose levels |
ES2392282T3 (es) * | 2004-02-13 | 2012-12-07 | Stem Cell Therapeutics Corp. | Uso de la hormona luteinizante (LH) y de la gonadotropina coriónica (hCG) para la proliferación de células precursoras neurales y la neurogénesis |
WO2006002532A1 (en) * | 2004-07-01 | 2006-01-12 | Waratah Pharmaceuticals, Inc. | Methods and compositions using cd3 agonists |
AU2005291810B2 (en) | 2004-10-07 | 2011-12-08 | Stem Cell Therapeutics Corp. | Stimulation of proliferation of pluripotential stem cells through administration of pregnancy associated compounds |
EP1928488A4 (de) | 2005-09-27 | 2009-07-22 | Stem Cell Therapeutics Corp | Regulierung der oligodendrozyten-vorläufer-zellproliferation mit prolactin |
JP2009510134A (ja) * | 2005-10-07 | 2009-03-12 | ワラタ ファーマシューティカルズ, インコーポレイテッド | Dpp−iv阻害剤およびガストリン化合物の組み合わせ使用 |
CA2632550C (en) * | 2005-12-15 | 2017-07-25 | Nestec S.A. | Medium chain triglycerides for preserving cognitive function |
WO2007076371A2 (en) | 2005-12-19 | 2007-07-05 | Pharmain Corporation | Hydrophobic core carrier compositions for delivery of therapeutic agents, methods of making and using the same |
EP2004212A4 (de) * | 2006-03-17 | 2010-07-14 | Stem Cell Therapeutics Corp | Kontinuierliche dosierschemata für neuralstammzellen-proliferierende mittel und neuralstammzellen-differenzierende mittel |
WO2008007933A1 (en) * | 2006-07-14 | 2008-01-17 | Postech Academy-Industry Foundation | Epidermal growth factor increasing insulin secretion and lowering blood glucose |
WO2008106775A1 (en) * | 2007-03-02 | 2008-09-12 | Waratah Pharmaceuticals Inc. | Combination treatment for diabetes using an egf receptor ligand and a gastrin compound |
US7960336B2 (en) * | 2007-08-03 | 2011-06-14 | Pharmain Corporation | Composition for long-acting peptide analogs |
US8563527B2 (en) * | 2007-08-20 | 2013-10-22 | Pharmain Corporation | Oligonucleotide core carrier compositions for delivery of nucleic acid-containing therapeutic agents, methods of making and using the same |
US20090176892A1 (en) | 2008-01-09 | 2009-07-09 | Pharmain Corporation | Soluble Hydrophobic Core Carrier Compositions for Delivery of Therapeutic Agents, Methods of Making and Using the Same |
JP5799397B2 (ja) | 2008-06-12 | 2015-10-28 | イプセン・バイオイノベーション・リミテッドIpsen Bioinnovation Limited | 癌の抑制 |
GB0820970D0 (en) | 2008-11-17 | 2008-12-24 | Syntaxin Ltd | Suppression of cancer |
WO2011131646A1 (en) * | 2010-04-20 | 2011-10-27 | Novo Nordisk A/S | Long-acting gastrin derivatives |
KR102027750B1 (ko) * | 2018-05-03 | 2019-10-02 | 연세대학교 산학협력단 | 당 배출용 조성물 |
WO2021002645A1 (ko) * | 2019-07-01 | 2021-01-07 | 연세대학교 산학협력단 | 하이드로겔 및 egfr 리간드를 유효성분으로 포함하는 당 배출용 조성물 |
KR102109385B1 (ko) * | 2019-08-21 | 2020-05-12 | 연세대학교 산학협력단 | 당 배출용 조성물 |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE38892B1 (en) * | 1973-03-28 | 1978-06-21 | Ici Ltd | Pharmaceutical compositions |
JPS6028994A (ja) * | 1983-07-08 | 1985-02-14 | Wakunaga Seiyaku Kk | 〔21―ロイシン〕ヒトウロガストロン |
GB8409961D0 (en) | 1984-04-17 | 1984-05-31 | Searle & Co | Pharmaceutical compositions |
US4686283A (en) * | 1985-04-16 | 1987-08-11 | Syntex (U.S.A.) Inc. | Analogs of transforming and epidermal growth factor fragments for therapy and diagnosis |
US5102789A (en) | 1989-03-15 | 1992-04-07 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Production of epideramal growth factor in pichia pastoris yeast cells |
US5158935A (en) | 1989-05-12 | 1992-10-27 | Chiron Corporation | Human epidermal growth factor having substitution at position 11 |
IE68593B1 (en) * | 1989-12-06 | 1996-06-26 | Sanofi Sa | Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them |
US5434135A (en) | 1990-08-02 | 1995-07-18 | Indu Parikh | Growth factor compositions, preparation and use |
AU2489992A (en) | 1991-08-16 | 1993-03-16 | Chiron Corporation | Muteins of epidermal growth factor exhibiting enhanced binding at low ph |
US6558952B1 (en) | 1992-12-14 | 2003-05-06 | Waratah Pharmaceuticals, Inc. | Treatment for diabetes |
US5885956A (en) * | 1992-12-14 | 1999-03-23 | Research Triangle Pharmaceuticals | Treatment for diabetes using a gastrin/CCK receptor ligand and an EGF receptor ligand |
EP1132091A1 (de) | 1994-01-24 | 2001-09-12 | The General Hospital Corporation | Behandlung von Diabetes |
GB9409496D0 (en) * | 1994-05-12 | 1994-06-29 | London Health Ass | Method for improving glycaemic control in diabetes |
US20040037818A1 (en) | 1998-07-30 | 2004-02-26 | Brand Stephen J. | Treatment for diabetes |
AU2153500A (en) | 1998-11-19 | 2000-06-05 | Millennium Pharmaceuticals, Inc. | Egf-like nucleic acids and polypeptides and uses thereof |
AU780794B2 (en) * | 1999-02-10 | 2005-04-14 | Es Cell International Pte Ltd | Pancreatic progenitor cells, methods and uses related thereto |
US6610535B1 (en) | 2000-02-10 | 2003-08-26 | Es Cell International Pte Ltd. | Progenitor cells and methods and uses related thereto |
WO2002055152A2 (en) * | 2001-01-12 | 2002-07-18 | Waratah Pharmaceuticals, Inc. | Composition for inducing islet neogenesis, containing gastrin/cck receptor ligands and egf receptor ligands |
WO2002079457A1 (en) * | 2001-03-29 | 2002-10-10 | Ixion Biotechnology, Inc. | Method for transdifferentiation of non-pancreatic stem cells to the pancreatic differentiation pathway |
US7037504B2 (en) | 2001-10-23 | 2006-05-02 | Waratah Pharmaceuticals, Inc. | Epidermal growth factor protein and gene, and methods of use therefor |
US20060234373A1 (en) | 2002-05-24 | 2006-10-19 | Alex Rabinovitch | Treatment for diabetes |
EP1837031B1 (de) | 2002-06-07 | 2009-10-14 | Waratah Pharmaceuticals, Inc. | Methoden und Kompositionen um Diabetes zu behandeln |
KR20050048542A (ko) | 2002-06-07 | 2005-05-24 | 와라타 파마수티컬즈, 인크. | 당뇨병의 치료를 위한 조성물 및 방법 |
KR20050074492A (ko) | 2002-10-22 | 2005-07-18 | 와라타 파마수티컬즈, 인크. | 당뇨병의 치료 |
US20040229810A1 (en) | 2002-10-22 | 2004-11-18 | Antonio Cruz | Gastrin compositions and formulations, and methods of use and preparation |
ES2307932T3 (es) | 2003-04-28 | 2008-12-01 | Pirelli Tyre S.P.A. | Neumatico que incluye una banda de rodadura con varias capas y su metodo de fabricacion. |
MXPA05012605A (es) | 2003-05-27 | 2006-02-22 | Waratah Pharmaceuticals Inc | Composiciones que comprenden compuestos de gastrina y sus usos en la diabetes. |
US20090202494A1 (en) | 2004-01-30 | 2009-08-13 | Antonio Cruz | Combined use of glp-1 agonists and gastrin for regulating blood glucose levels |
WO2006002532A1 (en) | 2004-07-01 | 2006-01-12 | Waratah Pharmaceuticals, Inc. | Methods and compositions using cd3 agonists |
JP2009510134A (ja) | 2005-10-07 | 2009-03-12 | ワラタ ファーマシューティカルズ, インコーポレイテッド | Dpp−iv阻害剤およびガストリン化合物の組み合わせ使用 |
WO2007062531A1 (en) | 2005-12-02 | 2007-06-07 | Waratah Pharmaceuticals, Inc. | Combination treatments with gastrin agonists for diabetes and related diseases |
WO2007095737A1 (en) | 2006-02-21 | 2007-08-30 | Waratah Pharmaceuticals Inc. | Combination therapy for the treatment of diabetes comprising an exendin agonist and a gastrin compound |
-
2002
- 2002-01-11 WO PCT/US2002/000685 patent/WO2002055152A2/en active Application Filing
- 2002-01-11 JP JP2002555881A patent/JP2004520345A/ja active Pending
- 2002-01-11 CN CNA028036824A patent/CN1486204A/zh active Pending
- 2002-01-11 IL IL15682802A patent/IL156828A0/xx unknown
- 2002-01-11 AU AU2002243501A patent/AU2002243501B2/en not_active Ceased
- 2002-01-11 ES ES02708990T patent/ES2315350T3/es not_active Expired - Lifetime
- 2002-01-11 US US10/044,048 patent/US6992060B2/en not_active Expired - Fee Related
- 2002-01-11 CA CA002434330A patent/CA2434330A1/en not_active Abandoned
- 2002-01-11 AT AT02708990T patent/ATE411077T1/de not_active IP Right Cessation
- 2002-01-11 DE DE60229352T patent/DE60229352D1/de not_active Expired - Fee Related
- 2002-01-11 EP EP02708990A patent/EP1351742B1/de not_active Expired - Lifetime
- 2002-01-11 KR KR10-2003-7009347A patent/KR20040064605A/ko not_active Application Discontinuation
-
2003
- 2003-07-10 ZA ZA200305347A patent/ZA200305347B/en unknown
-
2005
- 2005-11-14 US US11/273,615 patent/US7476388B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE60229352D1 (de) | 2008-11-27 |
US6992060B2 (en) | 2006-01-31 |
CN1486204A (zh) | 2004-03-31 |
AU2002243501B2 (en) | 2007-11-22 |
JP2004520345A (ja) | 2004-07-08 |
US20060234932A1 (en) | 2006-10-19 |
US7476388B2 (en) | 2009-01-13 |
ES2315350T3 (es) | 2009-04-01 |
EP1351742B1 (de) | 2008-10-15 |
WO2002055152A9 (en) | 2003-01-23 |
IL156828A0 (en) | 2004-02-08 |
US20020098178A1 (en) | 2002-07-25 |
ZA200305347B (en) | 2004-10-11 |
KR20040064605A (ko) | 2004-07-19 |
WO2002055152A2 (en) | 2002-07-18 |
CA2434330A1 (en) | 2002-07-18 |
EP1351742A2 (de) | 2003-10-15 |
WO2002055152A8 (en) | 2002-11-14 |
WO2002055152A3 (en) | 2003-04-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |