GR3019179T3 - Flupirtine in combination with antiparkinsonica against muscle bracing - Google Patents

Flupirtine in combination with antiparkinsonica against muscle bracing

Info

Publication number
GR3019179T3
GR3019179T3 GR960400581T GR960400581T GR3019179T3 GR 3019179 T3 GR3019179 T3 GR 3019179T3 GR 960400581 T GR960400581 T GR 960400581T GR 960400581 T GR960400581 T GR 960400581T GR 3019179 T3 GR3019179 T3 GR 3019179T3
Authority
GR
Greece
Prior art keywords
flupirtine
antiparkinsonica
combination
against muscle
muscle bracing
Prior art date
Application number
GR960400581T
Other languages
Greek (el)
English (en)
Inventor
Michael Dr Lobisch
Ralph Dr Venhaus
Bernd Dr Nickel
Istvan Prof Szelenyi
Juergen Prof Engel
Peter Dr Emig
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of GR3019179T3 publication Critical patent/GR3019179T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyrrole Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Golf Clubs (AREA)
  • Details Of Television Scanning (AREA)
  • Paints Or Removers (AREA)
GR960400581T 1990-07-14 1996-03-05 Flupirtine in combination with antiparkinsonica against muscle bracing GR3019179T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4022442 1990-07-14
IN421CA1991 IN172468B (OSRAM) 1990-07-14 1991-06-04

Publications (1)

Publication Number Publication Date
GR3019179T3 true GR3019179T3 (en) 1996-06-30

Family

ID=25895002

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960400581T GR3019179T3 (en) 1990-07-14 1996-03-05 Flupirtine in combination with antiparkinsonica against muscle bracing

Country Status (30)

Country Link
US (2) US5162346A (OSRAM)
EP (2) EP0467164B1 (OSRAM)
KR (1) KR0182811B1 (OSRAM)
CN (1) CN1070700C (OSRAM)
AT (2) ATE133564T1 (OSRAM)
AU (1) AU634073B2 (OSRAM)
CA (1) CA2046943C (OSRAM)
CZ (1) CZ280879B6 (OSRAM)
DE (3) DE59109222D1 (OSRAM)
DK (2) DK0467164T3 (OSRAM)
EG (1) EG19814A (OSRAM)
ES (2) ES2082887T3 (OSRAM)
GR (1) GR3019179T3 (OSRAM)
HR (1) HRP920667B1 (OSRAM)
HU (1) HU206973B (OSRAM)
IE (1) IE74688B1 (OSRAM)
IL (1) IL98810A (OSRAM)
IN (1) IN172468B (OSRAM)
LT (1) LT3593B (OSRAM)
LV (1) LV10048B (OSRAM)
MC (1) MC2272A1 (OSRAM)
MX (1) MX9100160A (OSRAM)
NO (1) NO912758L (OSRAM)
NZ (1) NZ238940A (OSRAM)
PT (1) PT98291B (OSRAM)
RO (1) RO108220B1 (OSRAM)
RU (1) RU2070408C1 (OSRAM)
SI (1) SI9111227B (OSRAM)
SK (1) SK279567B6 (OSRAM)
ZA (1) ZA915466B (OSRAM)

Families Citing this family (39)

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ES2111659T3 (es) * 1992-03-11 1998-03-16 Asta Medica Ag Comprimidos, granulados y nodulos con alto contenido en sustancias activas para formas de administracion solidas de alta concentracion.
DE4319649A1 (de) * 1993-03-18 1994-09-22 Asta Medica Ag Feste Flupirtin enthaltende orale Darreichungsformen mit kontrollierter Wirkstoffabgabe
DE4327516A1 (de) * 1993-08-17 1995-02-23 Asta Medica Ag Primäre und sekundäre neuroprotektive Wirkung bei neurodegenerativen Erkrankungen von Flupirtin
GB9426079D0 (en) * 1994-12-23 1995-02-22 Orion Yhtymae Oy A gelatine capsule
DE19541405A1 (de) * 1995-11-07 1997-05-15 Asta Medica Ag Verwendung von Flupirtin zur Prophylaxe und Therapie von Erkrankungen, die mit einer Beeinträchtigung des hämatopoetischen Zellsystems einhergehen
US6284794B1 (en) 1996-11-05 2001-09-04 Head Explorer Aps Method for treating tension-type headache with inhibitors of nitric oxide and nitric oxide synthase
US6610324B2 (en) * 1999-04-07 2003-08-26 The Mclean Hospital Corporation Flupirtine in the treatment of fibromyalgia and related conditions
CZ2002411A3 (cs) * 1999-08-03 2003-03-12 Awd. Pharma Gmbh & Co. Kg Farmaceutický prostředek pro léčení bolesti stejně jako prevenci chronických bolestí při degenerativních chorobách kloubů u psů a koček
US6821995B1 (en) 1999-12-01 2004-11-23 Duke University Method of treating batten disease
US20040122090A1 (en) * 2001-12-07 2004-06-24 Lipton Stuart A. Methods for treating neuropsychiatric disorders with nmda receptor antagonists
RU2213565C1 (ru) * 2002-06-24 2003-10-10 Общество с ограниченной ответственностью "Паркинфарм" Способ лечебного воздействия на организм пациента при лечении болезни паркинсона
DE10255415A1 (de) * 2002-11-28 2004-06-09 Bayer Healthcare Ag Dermale Applikation von Flupirtin
DE10327674A1 (de) * 2003-06-20 2005-01-05 Awd.Pharma Gmbh & Co. Kg Injizierbare Darreichungsform von Flupirtin
US20050089559A1 (en) 2003-10-23 2005-04-28 Istvan Szelenyi Combinations of potassium channel openers and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains
DE102004001558A1 (de) * 2004-01-10 2005-08-18 Bayer Healthcare Ag Arzneimittel zur topischen Applikation bei Tieren
US20050196461A1 (en) * 2004-01-14 2005-09-08 Udell Ronald G. Ceramide formulations suitable for oral administration
US20050245617A1 (en) * 2004-01-29 2005-11-03 Meyerson Laurence R Methods and compositions for the treatment of CNS-related conditions
US20050220862A1 (en) 2004-03-31 2005-10-06 Bernstein Joel E Compositions with reduced hepatotoxicity
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
EP1688141A1 (en) * 2005-01-31 2006-08-09 elbion AG The use of flupirtine for the treatment of overactive bladder and associated diseases, and for the treatment of irritable bowel syndrome
MX2007012374A (es) 2005-04-06 2008-02-22 Adamas Pharmaceuticals Inc Metodos y composiciones para el tratamiento de condiciones relacionadas con cns.
JP2009535370A (ja) * 2006-05-02 2009-10-01 クリス ルントフェルト ジストニアおよびジストニア様症状の予防および治療におけるカリウムチャンネル活性剤
US7960436B2 (en) 2006-06-05 2011-06-14 Valeant Pharmaceuticals International Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators
PL2061465T3 (pl) * 2006-08-23 2014-03-31 Valeant Pharmaceuticals Int Pochodne 4-(N-azacykloalkilo) anilidów jako modulatory kanałów potasowych
US8993593B2 (en) * 2006-08-23 2015-03-31 Valeant Pharmaceuticals International N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators
US8722929B2 (en) * 2006-10-10 2014-05-13 Valeant Pharmaceuticals International N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators
JP2010511052A (ja) * 2006-11-28 2010-04-08 バレアント ファーマシューティカルズ インターナショナル カリウムチャネル調節因子としての１，４ジアミノ二環式レチガビンアナログ
US20080279930A1 (en) * 2007-05-07 2008-11-13 Bernd Terhaag Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
CA2694887A1 (en) * 2007-08-01 2009-02-05 Henriette Husum Bak-Jensen Use of kncq potassium channel openers for reducing symptoms of or treating disorders or conditions wherein the dopaminergic system is disrupted
US8563566B2 (en) * 2007-08-01 2013-10-22 Valeant Pharmaceuticals International Naphthyridine derivatives as potassium channel modulators
US7786146B2 (en) * 2007-08-13 2010-08-31 Valeant Pharmaceuticals International Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
ES2347119B2 (es) * 2009-04-22 2011-04-28 Universidad De Santiago De Compostela Nanocapsulas de poliarginina.
DE102010030053A1 (de) 2010-06-14 2011-12-15 Awd.Pharma Gmbh & Co.Kg Injizierbare Darreichungsform von Flupirtin
JP6251667B2 (ja) * 2014-06-03 2017-12-20 アサヒカルピスウェルネス株式会社 錠剤型即放性製剤及びその製造方法
DE102017007385A1 (de) 2017-08-02 2019-02-07 Christoph Hoock Maleatfreie feste Arzneimittelformen
TWI886158B (zh) 2019-10-10 2025-06-11 加拿大商再諾製藥公司 選擇性鉀通道調節劑之固態晶型
BR112022008580A2 (pt) 2019-11-08 2022-08-09 Xenon Pharmaceuticals Inc Métodos para tratar transtornos depressivos
TW202245744A (zh) 2021-02-09 2022-12-01 加拿大商再諾製藥公司 治療失樂症之方法及用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1795858C2 (de) 1968-07-19 1979-01-11 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt Benzylaminopyridine
DE3133519A1 (de) 1980-09-13 1982-06-09 Degussa Ag, 6000 Frankfurt "2-amino-3-carbethoxyamino-6-(p-fluor-benzylamino)-pyridin-maleat"
DE3665538D1 (en) * 1985-01-23 1989-10-19 Asta Pharma Ag Synergistic combination of flupirtin and non-steroidal anti-phlogistics
DE3604575A1 (de) * 1985-02-23 1986-08-28 Degussa Ag, 6000 Frankfurt Kombination von flupirtin und anticholinergisch wirkenden spasmolytika
DE3663775D1 (en) * 1985-02-23 1989-07-13 Asta Pharma Ag Combination of flupirtin with spasmolytics having an anticholinergic effect
FI855016L (fi) * 1985-06-28 1986-12-29 Degussa Synergistisk kombination av flupirtin och 4-acetamido-fenol.

Also Published As

Publication number Publication date
EP0467164A2 (de) 1992-01-22
IE74688B1 (en) 1997-07-30
HU912359D0 (en) 1991-12-30
EP0659410B1 (de) 2001-10-17
LTIP919A (en) 1995-03-27
ATE206919T1 (de) 2001-11-15
ATE133564T1 (de) 1996-02-15
LV10048A (lv) 1994-05-10
PT98291A (pt) 1992-05-29
HRP920667A2 (en) 1996-10-31
EP0467164A3 (en) 1992-04-15
DE59107331D1 (de) 1996-03-14
NO912758D0 (no) 1991-07-12
US5284861A (en) 1994-02-08
RO108220B1 (ro) 1994-03-31
US5162346A (en) 1992-11-10
DK0467164T3 (da) 1996-03-04
HRP920667B1 (en) 1998-06-30
NZ238940A (en) 1997-05-26
NO912758L (no) 1992-01-15
LV10048B (en) 1995-06-20
IL98810A0 (en) 1992-07-15
HU206973B (en) 1993-03-01
CZ280879B6 (cs) 1996-04-17
EP0659410A2 (de) 1995-06-28
MX9100160A (es) 1992-02-28
EG19814A (en) 1996-02-29
EP0467164B1 (de) 1996-01-31
AU8040391A (en) 1992-01-16
ES2164111T3 (es) 2002-02-16
CA2046943C (en) 1996-03-12
AU634073B2 (en) 1993-02-11
ZA915466B (en) 1992-04-29
CN1058716A (zh) 1992-02-19
SI9111227A (en) 1995-06-30
MC2272A1 (fr) 1993-06-23
RU2070408C1 (ru) 1996-12-20
HUT59313A (en) 1992-05-28
CN1070700C (zh) 2001-09-12
LT3593B (en) 1995-12-27
CA2046943A1 (en) 1992-01-15
IN172468B (OSRAM) 1993-08-14
IE912451A1 (en) 1992-01-15
SI9111227B (sl) 2000-12-31
SK279567B6 (sk) 1999-01-11
EP0659410A3 (de) 1995-10-25
KR0182811B1 (ko) 1999-05-01
PT98291B (pt) 1999-01-29
DE59109222D1 (de) 2001-11-22
IL98810A (en) 1996-01-19
ES2082887T3 (es) 1996-04-01
DK0659410T3 (da) 2001-12-27
CS210191A3 (en) 1992-02-19
DE4122166A1 (de) 1992-01-16
KR920002147A (ko) 1992-02-28

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