GR3005844T3 - - Google Patents
Info
- Publication number
- GR3005844T3 GR3005844T3 GR920402178T GR920402178T GR3005844T3 GR 3005844 T3 GR3005844 T3 GR 3005844T3 GR 920402178 T GR920402178 T GR 920402178T GR 920402178 T GR920402178 T GR 920402178T GR 3005844 T3 GR3005844 T3 GR 3005844T3
- Authority
- GR
- Greece
- Prior art keywords
- aminobenzothiazole
- antitumor agents
- acyl derivatives
- alkylated analogs
- alkylated
- Prior art date
Links
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Graft Or Block Polymers (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19803488A | 1988-05-24 | 1988-05-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3005844T3 true GR3005844T3 (cg-RX-API-DMAC7.html) | 1993-06-07 |
Family
ID=22731735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR920402178T GR3005844T3 (cg-RX-API-DMAC7.html) | 1988-05-24 | 1992-09-30 |
Country Status (25)
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2790299B2 (ja) * | 1989-02-01 | 1998-08-27 | 保土谷化学工業株式会社 | ペンゾチアゾール誘導体 |
| US5262400A (en) * | 1991-06-20 | 1993-11-16 | Merck & Co., Inc. | 4α-substituted avermectin derivatives |
| PT850221E (pt) * | 1995-08-30 | 2001-11-30 | Searle & Co | Derivados de meta-guanidina ureia tioureia ou acido aminobenzoico azaciclico como antagonistas de integrina |
| US6100423A (en) * | 1995-08-30 | 2000-08-08 | G. D. Searle & Co. | Amino benzenepropanoic acid compounds and derivatives thereof |
| US5716281A (en) * | 1995-11-27 | 1998-02-10 | Sega Enterprises, Ltd. | Game apparatus using a vehicle with an optical image synthesizing system |
| TW513418B (en) * | 1996-07-31 | 2002-12-11 | Otsuka Pharma Co Ltd | Thiazole derivatives, their production and use |
| DE69833224T2 (de) | 1997-11-10 | 2006-09-28 | Bristol-Myers Squibb Co. | Benzothiazole als protein tyrosin-kinase inhibitoren |
| EP0928793B1 (en) * | 1998-01-02 | 2002-05-15 | F. Hoffmann-La Roche Ag | Thiazole derivatives |
| AU3406599A (en) * | 1998-04-09 | 1999-11-01 | Institut Fur Diagnostikforschung Gmbh An Der Freien Universitat Berlin | Novel benzyl guanidine derivatives for therapy and (in-vivo) and (in-vitro) diagnosis |
| ATE385794T1 (de) | 2000-06-21 | 2008-03-15 | Hoffmann La Roche | Benzothiazolderivate zur behandlung von alzheimer und parkinson |
| US6620811B2 (en) * | 2001-11-19 | 2003-09-16 | Hoffmann-La Roche Inc. | Isonicotin- and nicotinamide derivatives of benzothiazoles |
| US6599901B1 (en) * | 2001-11-19 | 2003-07-29 | Hoffman-La Roche Inc. | Pyridone substituted benzothiazole derivatives |
| US6624163B2 (en) * | 2001-11-29 | 2003-09-23 | Hoffman-La Roche Inc. | Benzothiazole derivatives |
| GB0130868D0 (en) | 2001-12-24 | 2002-02-06 | Univ Strathclyde | New compounds |
| CN100357283C (zh) * | 2002-04-02 | 2007-12-26 | 中国科学院上海药物研究所 | 一类甲硫氨酰氨肽酶抑制剂 |
| US7087761B2 (en) | 2003-01-07 | 2006-08-08 | Hoffmann-La Roche Inc. | Cyclization process for substituted benzothiazole derivatives |
| AU2004238508B2 (en) * | 2003-05-13 | 2009-11-19 | F. Hoffmann-La Roche Ag | Imidazo-benzothiazoles |
| PL1636223T3 (pl) * | 2003-05-19 | 2008-07-31 | Hoffmann La Roche | Pochodne benzotiazolu jako ligandy receptora adenozynowego |
| DE602004004776T2 (de) * | 2003-05-21 | 2007-11-22 | F. Hoffmann-La Roche Ag | Benzothiazol derivate und ihre anwendung in der behandlung von adenosin a2a rezeptor vermittelten krankheiten # |
| CA2527174C (en) * | 2003-05-30 | 2014-03-25 | F.Hoffmann-La Roche Ag | Benzothiazole derivatives and use thereof in the treatment of diseases related to the adenosine a2a receptor |
| KR20060054408A (ko) * | 2003-07-28 | 2006-05-22 | 얀센 파마슈티카 엔.브이. | 벤즈이미다졸, 벤즈티아졸 및 벤즈옥사졸 유도체 및ｌｔａ4 ｈ 조정자로서의 그의 용도 |
| ATE382619T1 (de) | 2004-05-24 | 2008-01-15 | Hoffmann La Roche | 4-hydroxy-4-methylpiperidin-1-carbonsäure-(4- methoxy-7-morpholin-4-ylbenzothiazol-2-yl)-amid |
| BRPI0513511A (pt) * | 2004-07-22 | 2008-05-06 | Hoffmann La Roche | derivados de benzotiazol |
| EP1773795A1 (en) * | 2004-07-22 | 2007-04-18 | F.Hoffmann-La Roche Ag | Substituted benzothiazoles |
| CN101056857B (zh) | 2004-11-05 | 2010-12-01 | 弗·哈夫曼-拉罗切有限公司 | 异烟酸衍生物的制备方法 |
| MX2007011483A (es) | 2005-03-23 | 2007-10-12 | Hoffmann La Roche | Derivados de acetilenil-pirazolo-pirimidina como antagonistas de glutamato metabotropico 2. |
| AU2006298829B2 (en) | 2005-09-27 | 2011-03-03 | F. Hoffmann-La Roche Ag | Oxadiazolyl pyrazolo-pyrimidines as mGluR2 antagonists |
| CN101405278A (zh) * | 2006-03-15 | 2009-04-08 | 4Sc股份公司 | 新颖的杂环NF-κB抑制剂 |
| GB0619325D0 (en) | 2006-09-30 | 2006-11-08 | Univ Strathclyde | New compounds |
| US20110178070A1 (en) * | 2008-06-24 | 2011-07-21 | Takeda Pharmaceutical Company Limited | PI3K/mTOR INHIBITORS |
| US9499790B2 (en) | 2010-08-26 | 2016-11-22 | Kyoto University | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells |
| WO2013049407A2 (en) * | 2011-09-30 | 2013-04-04 | Kineta, Inc | Anti-viral compounds |
| WO2013111875A1 (ja) | 2012-01-27 | 2013-08-01 | 国立大学法人京都大学 | 多能性幹細胞の心筋分化誘導法 |
| WO2014136519A1 (ja) | 2013-03-08 | 2014-09-12 | 国立大学法人京都大学 | Ｅｇｆ受容体阻害剤を含む多能性幹細胞の心筋分化促進剤 |
| WO2015037706A1 (ja) * | 2013-09-13 | 2015-03-19 | 国立大学法人京都大学 | 多能性幹細胞の心筋分化を促進する化合物 |
| WO2015182765A1 (ja) | 2014-05-30 | 2015-12-03 | 国立大学法人京都大学 | 低分子化合物を用いた多能性幹細胞の心筋分化誘導法 |
| CN109776486A (zh) * | 2019-02-26 | 2019-05-21 | 武汉松石科技股份有限公司 | 一种硫酸亚丙酯的制备方法 |
| CN110590735B (zh) * | 2019-09-30 | 2021-07-23 | 江苏国泰超威新材料有限公司 | 一种环状硫酸酯的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61225168A (ja) * | 1985-03-30 | 1986-10-06 | Nippon Tokushu Noyaku Seizo Kk | 新規ベンズアミド、その製法及び殺虫剤 |
| KR930005004B1 (ko) * | 1985-04-15 | 1993-06-11 | 쟈안센 파아마슈우티카 엔. 부이. | 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법 |
| GB8611606D0 (en) * | 1986-05-13 | 1986-06-18 | Fbc Ltd | Fungicides |
-
1989
- 1989-05-18 IL IL90337A patent/IL90337A0/xx unknown
- 1989-05-22 EP EP89305141A patent/EP0343893B1/en not_active Expired - Lifetime
- 1989-05-22 JP JP1128600A patent/JPH0678331B2/ja not_active Expired - Lifetime
- 1989-05-22 AT AT89305141T patent/ATE79114T1/de not_active IP Right Cessation
- 1989-05-22 ES ES89305141T patent/ES2043012T3/es not_active Expired - Lifetime
- 1989-05-22 PT PT90622A patent/PT90622B/pt not_active IP Right Cessation
- 1989-05-22 DE DE8989305141T patent/DE68902358T2/de not_active Expired - Lifetime
- 1989-05-23 HU HU892578A patent/HU202507B/hu not_active IP Right Cessation
- 1989-05-23 ZA ZA893862A patent/ZA893862B/xx unknown
- 1989-05-23 CA CA000600370A patent/CA1328871C/en not_active Expired - Fee Related
- 1989-05-23 FI FI892498A patent/FI892498A7/fi not_active Application Discontinuation
- 1989-05-23 MX MX016158A patent/MX173140B/es unknown
- 1989-05-23 DD DD89328832A patent/DD283815A5/de not_active IP Right Cessation
- 1989-05-23 IE IE891667A patent/IE891667L/xx unknown
- 1989-05-23 NO NO892059A patent/NO172389C/no unknown
- 1989-05-23 MY MYPI89000689A patent/MY106035A/en unknown
- 1989-05-23 NZ NZ229234A patent/NZ229234A/en unknown
- 1989-05-23 AU AU35098/89A patent/AU601905B2/en not_active Ceased
- 1989-05-23 DK DK249389A patent/DK249389A/da unknown
- 1989-05-23 KR KR1019890006889A patent/KR910006864B1/ko not_active Expired
- 1989-05-23 SU SU894614242A patent/SU1681728A3/ru active
- 1989-05-24 CN CN89103540A patent/CN1023700C/zh not_active Expired - Fee Related
- 1989-05-24 YU YU105989A patent/YU47019B/sh unknown
- 1989-05-24 PL PL1989279613A patent/PL154875B1/pl unknown
-
1992
- 1992-09-30 GR GR920402178T patent/GR3005844T3/el unknown
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